This paper gives a formalization of general topology in second-order arithmetic using countably based MF spaces. This formalization is used to study the reverse mathematics of general topology. For each poset P we let MF denote the set of maximal filters on P endowed with the topology generated by {Np | p ∈ P}, where Np = {F ∈ MF | p ∈ F}. We define a countably based MF space to be a space of the form MF for some (...) countable poset P. The class of countably based MF spaces includes all complete separable metric spaces as well as many nonmetrizable spaces. The following reverse mathematics results are obtained. The proposition that every nonempty Gδ subset of a countably based MF space is homeomorphic to a countably based MF space is equivalent to [Formula: see text] over ACA0. The proposition that every uncountable closed subset of a countably based MF space contains a perfect set is equivalent over [Formula: see text] to the proposition that [Formula: see text] is countable for all A ⊆ ℕ. The proposition that every regular countably based MF space is homeomorphic to a complete separable metric space is equivalent to [Formula: see text] over [Formula: see text]. (shrink)