With the aid of the Cahiers de laboratoire, the Correspondance and, of course, the Oeuvre de Pasteur, this work reconstructs the extraordinary scientific undertakings of the great French scientist in his study of silkworm diseases. The focus of this study consists in the attempt to explain the initial perplexing behaviour of Pasteur, even in the presence of correct interpretations regarding the causes of these diseases (cfr. the results obtained by Béchamp); for a good three years he insisted on maintaining that (...) the aetiology of silkworm diseases could not be attributed to pathogenetic germs from outside. And this was in spite of the fact that previously (through fermentation and spontaneous generation) he had been able to demonstrate the importance of micro-organisms in biological processes. Finally it is intended to highlight the extraordinary methodological depth of that initial 'error', which was capable of paving the way for the future conquests of Pasteur in the field of aetiology and the prevention of infectious diseases. (shrink)

No one has a well developed solution to Duhem's problem, the problem of how experimental evidence warrants revision of our theories. Deborah Mayo proposes a solution to Duhem's problem in route to her more ambitious program of providing a philosophical account of inductive inference and experimental knowledge. This paper is a response to Mayo's Error Statistics (ES) program, paying particular attention to her response to Duhem's problem. It turns out that Mayo's purported solution to Duhem's problem is very significant to (...) her project, for the epistemic license claimed by ES and the philosophical underpinnings to her account of experimental knowledge depend on this solution. By introducing the partition problem, I argue that ES fails to solve Duhem's problem and therefore fails to provide an adequate account of experimental knowledge. (shrink)

It is sometimes held that facts confirm a hypothesis only if they were not used in the construction of that hypothesis. This requirement of "use novelty" introduces a historical aspect into the assessment of evidence claims. I examine a methodological principle invoked by physicists in the experimental search for the top quark that bears a striking resemblance to this view. However, this principle is better understood, both historically and philosophically, in terms of the need to conduct a severe test than (...) in terms of use novelty. Nevertheless, a historical factor remains in the assessment of some evidence claims. (shrink)

It is sometimes held that facts confirm a hypothesis only if they were not used in the construction of that hypothesis. This requirement of "use novelty" introduces a historical aspect into the assessment of evidence claims. I examine a methodological principle invoked by physicists in the experimental search for the top quark that bears a striking resemblance to this view. However, this principle is better understood, both historically and philosophically, in terms of the need to conduct a severe test than (...) in terms of use novelty. Nevertheless, a historical factor remains in the assessment of some evidence claims. (shrink)

Romantic Naturphilosophie has been at the centre of almost every account of early nineteenth-century sciences, be it as an obstacle or as an aid for scientific advancement. The following paper suggests a change of perspective. I seek to read Naturphilosophie as one manifestation among others of a more general concern with the question of how experience enables the subject to acquire knowledge about objects. To illustrate such an approach, I focus on Johannes Muller's early work. Here one finds two contrasting (...) images of microscopical observation, its set-up, and the observer: the embryological study of 1830 demands a 'philosophical grasp' of the appearances. In contrast, the investigations of blood of 1832 are presented as a series of controlled experiments. I argue that an interpretation of this contrast in terms of an appropriation and casting aside of Naturphilosophie is not altogether convincing. Instead, both images of microscopy are manifestations of a more general problem, namely, the problem of exactly how subject and object came together in experience. I show how this concern not only shaped the methodological sensibilities particular to Muller's embryology and the investigation of bodily liquids but also provided the epistemological principles and the target for his sense-physiological experiments. It bound Muller's work together with Naturphilosophie and linked Naturphilosophie with other contemporaneous projects in philosophy. All of these enterprises sought to contribute to ongoing debates about how experience allowed the subject to acquire knowledge about the world. (shrink)

: Bayesians and error statisticians have relied heavily upon examples from physics in developing their accounts of scientific inference. The present essay demonstrates it is possible to analyze H.B.D. Kettlewell's classic study of natural selection from Deborah Mayo's error statistical point of view (Mayo 1996). A comparison with a previous analysis of this episode from a Bayesian perspective (Rudge 1998) reveals that the error statistical account makes better sense of investigations such as Kettlewell's because it clarifies how core elements in (...) the design of experiments are used to minimize erroneous inferences rather than dwelling on whether the strategies used are reasonable. (shrink)

This paper is concerned with the problem of experimental error. The prevalent view that experimental errors can be dismissed as a tiresome but trivial blemish on the method of experimentation is criticized. It is stressed that the occurrence of errors in experiments constitutes a permanent feature of the attempt to test theories in the physical world, and this feature deserves proper attention. It is suggested that a classification of types of experimental error may be useful as a heuristic device in (...) studying the nature of these errors. However, the standard classification of systematic and random errors is mathematically based does not focus on the causes of the errors, their origins, or the contexts in which they arise. A new typology of experimental errors is therefore proposed whose criterion is epistemological. This typology reflects the various stages that can be discerned in the execution of an experiment, each stage constituting a category of a certain type of experimental error. The proposed classification consists of four categories which are illustrated by historical cases. (shrink)

SummaryThis paper is an account of Kepler's explicit awareness of the problem of experimental error. As a study of the Astronomia nova shows, Kepler exploited his awareness of the occurrences of experimental errors to guide him to the right conclusion. Errors were thus employed, so to speak, perhaps for the first time, to bring about a major physical discovery: Kepler's laws of planetary motion. ‘Know then’, to use Kepler's own words, ‘that errors show us the way to truth.’ With a (...) survey of Kepler's revolutionary contribution to optics, the paper demonstrates that Kepler's awareness of the problem of experimental error extended beyond discrepancies between calculations and observations to types of error which pertain to observations and instruments. It emerges that Kepler's belief in the unity of knowledge and physical realism, facilitated—indeed created—the right philosophical posture for comprehending the problem of error in an entirely novel way. (shrink)

: During the "institutional revolution" between 1870 and 1910 almost two dozen physics institutes were newly erected in Germany. The design of these buildings was largely determined by sets of precautions against various sorts of disturbances. These undertakings were by no means unique. Recent historical studies have identified similar attempts in physics institutes outside Germany. But as yet, hardly a word has been wasted on the necessity of these precautionary measures. It seems to be self-explanatory that disturbances should be precluded (...) from scientific investigations. My paper criticizes this approach. The evidential nature of this assertion rests on the questionable assumption that disturbances are "external factors," which hinder physical research. I examine the 'architecture of disturbance' and show that it is the set of precautions itself which sometimes produces 'disturbing' effects. I then focus on particular sources of disturbance that were taken into account in the design of the buildings, and analyze the aporias that characterize the 'external' definition of disturbances. In conclusion, an alternative understanding of disturbances is offered. Following Michel Serres's concept of the parasite, I suggest that disturbances indicate the "being of relation" in physics research around 1900. From this point of view I finally sketch two novel features that governed the design of physics institutes after the turn of the century. (shrink)

: Errors in science range along a spectrum from those relatively local to the phenomenon (usually easily remedied in the laboratory) to those more conceptually derived (involving theory or cultural factors, sometimes quite long-term). One may classify error types broadly as material, observational, conceptual or discoursive. This framework bridges philosophical and sociological perspectives, offering a basis for interfield discourse. A repertoire of error types also supports error analytics, a program for deepening reliability through strategies for regulating and probing error.

It is ironic that the prototype of the oscilloscope--for that is what Hertz's apparatus amounted to--should be instrumental in demonstrating that cathode rays have no closer relation to electricity than has light produced by an electric lamp. Indeed, Hertz argued that since "cathode rays are electrically indifferent,... the phenomenon most nearly allied to them is light.".