Are physics and chemistry sufficient to provide a basis for a theory of everything? The worldview of materialist naturalism that forms the foundation of NeoDarwinian evolution, Big Bang cosmogony, and molecular biology in general has been subjected to challenge for its monumental failure to explain life, consciousness and other mind-related aspects of reality. Two recent books, Why Evolution is True by Jerry Coyne [1], and Thomas Nagel’s Mind and Cosmos: Why the Materialist NeoDarwinian Conception of Nature Is Almost Certainly False (...) [2], both authors being atheists, reflect the deep rift we find, not only in the religious conflict between creation and evolution, but in the fundamental awareness we all have that we are more than just molecular matter. This common sense understanding can only escape the notice of a particularly shallow ideological dogmatism that insists it has all the answers based solely on its unprecedented technological success. Science has come to represent two different things: (a) a body of knowledge, and (b) a method for acquiring knowledge. The problem arises when it is forgotten that there is no independent body of knowledge for science apart from its method – it keeps changing according to the results of the latest findings of the scientific method. The method is not to be abandoned because of those who would like to replace it with a fixed body of knowledge, which then becomes ideology. If biogenesis is hypothesized as the law of Nature, and we observe that life comes from pre-existing life in all our experience, while the hypothesis of abiogenesis, that life comes from matter, is never backed by any observation, then according to the scientific method—which one is to be accepted as true scientific knowledge? Obviously, the one backed by empirical observation. It is necessary to get free of ideological “knowledge,” and return to science as a method for gathering evidence that may lead to conclusions beyond the material naturalist view of Nature, and conforms to what we experience and rationally understand about the world in which we live. (shrink)

Origin of life studies have presented one of the most serious challenges to the mechanistic conception that life can be explained scientifically as a mere product of chemistry and physics. Hypotheses about the origin of life can be divided into two categories: (1) biogenesis – life comes from life, and (2) abiogenesis – life comes from non-living matter. The theory of the spontaneous generation of life from inanimate matter had been held even by the ancient Greeks and by numerous (...) scientists well into the 19th century. The theory of abiogenesis poses many problems for understanding the origin of life on Earth, and the appearance of life early in Earth’s history. Numerous chemical, mathematical and informational problems arise which make random mechanical processes of cellular formation and function unlikely. Fossil evidence contradicts a gradualist evolutionary mechanism of development of life, especially the well-known Cambrian explosion, in which highly developed metazoan species suddenly appear in the geological column without intermediate predecessors. But the physical conundrums that mechanistic theories of chemistry and physics face are only one side of the problem. Along with a rising chorus of philosophers, Thomas Nagel, an atheist philosopher, has protested that essential questions about the origin of life, and features such as mind, intelligence and morality are completely left unexplained by mechanistic evolutionary theories. In Mind and Cosmos: Why the Materialist Neo-Darwinian Conception of Nature Is Almost Certainly False, Nagel plainly lays out his argument that the modern materialist approach to life has conspicuously failed to explain something so integral to nature as mind or consciousness, thereby threatening to unravel the entire naturalistic world picture of biology, evolutionary theory and cosmology. [13] As an alternative he argues that at least natural teleological principles must be admitted to play a role in our view of science. He writes: “Each of our lives is a part of the lengthy process of the universe gradually waking up and becoming aware of itself.” The Vedantic view of the Absolute as sentient conceives of Bhagavan as the conscious and consequently personal source of the universe. This view holds that life is fundamental, and not merely coextensive with matter. It is thus consistent with the law of biogenesis which is scientifically established in agreement with empirical evidence. Life is the basis of Nature, not matter, and Nature is a system in which the different species are nodes or niches, each possessed of variety and adaptability. Evolution is of consciousness, not of the bodies of organisms. The sedimentary fossils are the result of catastrophic deposits, and are thus not indicative of gradual evolution which is concluded only on the questionable assumption of uniformitarianism. (shrink)

I argue for an idealist ontology consistent with empirical observations, which seeks to explain the facts of nature more parsimoniously than physicalism and bottom-up panpsychism. This ontology also attempts to offer more explanatory power than both physicalism and bottom-up panpsychism, in that it does not fall prey to either the ‘hard problem of consciousness’ or the ‘subject combination problem’, respectively. It can be summarized as follows: spatially unbound consciousness is posited to be nature’s sole ontological primitive. We, as well as (...) all other living organisms, are dissociated alters of this unbound consciousness. The universe we see around us is the extrinsic appearance of phenomenality surrounding—but dissociated from—our alter. The living organisms we share the world with are the extrinsic appearances of other dissociated alters. As such, the challenge to artificially create individualized consciousness becomes synonymous with the challenge to artificially induce abiogenesis. (shrink)

In the abiogenesis hypothesis, self-replicating RNA is generally assumed to have arisen out of a primordial soup of amino acids no later than 500 million years before life on Earth. Recently, prebiotic molecules such as glycolaldehyde and amino acetonitrile were found to be abundant in nebulas such as Sagittarius B2. In this paper I propose that icy grains within nebulas can act as tiny primordial soups, and I investigate the consequences of such. I further argue that a typical nebula (...) would be astronomically more likely to create a self-replicator than the combined iterative power available in Earth’s primitive oceans. Finding the first self-replicator could be a problem significantly more difficult than previously envisioned, requiring the contribution of a larger primordial soup spread across a nebula and operating for billions of years prior to life on Earth. Finally, we discuss the Fermi paradox in the context of a mechanism by which life could be expected to lag the Big Bang by 10 billion years, hence suggesting that we may not only be alone, but also not inconceivably the first. (shrink)

In the past, philosophers, scientists, and even the general opinion, had no problem in accepting the existence of consciousness in the same way as the existence of the physical world. After the advent of Newtonian mechanics, science embraced a complete materialistic conception about reality. Scientists started proposing hypotheses like abiogenesis (origin of first life from accumulation of atoms and molecules) and the Big Bang theory (the explosion theory for explaining the origin of universe). How the universe came to be (...) what it is now is a key philosophical question. The hypothesis that it came from Nothing (as proposed by Stephen Hawking, among others), proves to be dissembling, since the quantum vacuum can hardly be considered a void. In modern science, it is generally assumed that matter existed before the universe came to be. Modern science hypothesizes that the manifestation of life on Earth is nothing but a mere increment in the complexity of matter — and hence is an outcome of evolution of matter (chemical evolution) following the Big Bang. After the manifestation of life, modern science believed that chemical evolution transformed itself into biological evolution, which then had caused the entire biodiversity on our planet. The ontological view of the organism as a complex machine presumes life as just a chance occurrence, without any inner purpose. This approach in science leaves no room for the subjective aspect of consciousness in its attempt to know the world as the relationships among forces, atoms, and molecules. On the other hand, the Vedāntic view states that the origin of everything material and nonmaterial is sentient and absolute (unconditioned). Thus, sentient life is primitive and reproductive of itself – omne vivum ex vivo – life comes from life. This is the scientifically verified law of experience. Life is essentially cognitive and conscious. And, consciousness, which is fundamental, manifests itself in the gradational forms of all sentient and insentient nature. In contrast to the idea of objective evolution of bodies, as envisioned by Darwin and followers, Vedānta advocates the idea of subjective evolution of consciousness as the developing principle of the world. In this paper, an attempt has been made to highlight a few relevant developments supporting a sentient view of life in scientific research, which has caused a paradigm shift in our understanding of life and its origin. (shrink)

Life on Earth descends from a common ancestor. However, it is likely that there are other instances of life in the universe. If so, each abiogenesis event will have given rise to an independently originated life clade, of which Earth-life is an example. In this paper, I argue that the set of all IOLCs in the universe forms a Darwinian population subject to natural selection, with more widely dispersed IOLCs being less likely to face extinction. As a result, we (...) should expect that, over time, more planets will become inhabited by fewer, more successful IOLCs. (shrink)

The monograph (Luisi P.L. "The Emergence of Life: From Chemical Origins to Synthetic Biology", 2010, Cambridge University Press, Cambridge, New York etc., 315 p.) is a well-written, informative book providing a novel view on the interrelation between the abiogenesis as the natural origin of life and synthetic biology as the artificial synthesis of life. This concept is specially known as autopoiesis. As its name implies, it is a correlate of self-organization, but this word has quite a broad meaning in (...) the literature. Consequently, some further restriction is required for this term in abiogenetic, as well as in "biogenetic" applications. There is, in fact, one basic reason for considering the abiogenetic problem in terms of self-organization theory. It follows from the extremely boundless complexity of biological systems. (shrink)

Abstract. The presumptuous philosopher (PP) thought experiment lends more credence to the hypothesis which postulates the existence of a larger number of observers than other hypothesis. The PP was suggested as a purely speculative endeavor. However, there is a class of real world observer-selection effects where it could be applied, and one of them is the possibility of interstellar panspermia (IP). There are two types of anthropic reasoning: SIA and SSA. SIA implies that my existence is an argument that larger (...) total number of observers exists; SSA implies that I should find myself in a region with larger number of observers. However, as S. Armstrong showed, SIA can’t distinguish between different ways how larger number of observers appeared, so it can’t favor IP compared with other ways to get many observers. SSA application here is less controversial as it tells only about relation between regions size: e.g. I am more likely to live in a larger country than in a small one, conditioning that the total number of small countries is also small. Anthropic considerations suggest that the universes in the multiverse with interstellar panspermia will have orders of magnitude more civilizations than universes without IP, and thus we are likely to be in such a universe. This is a strong counterargument against a variant of the Rare Earth hypothesis based on the difficulty of abiogenesis: even if abiogenesis is difficult, IP will disseminate life over billions of planets, meaning we are likely to find ourselves in a universe where IP has happened. This implies that there should be many planets with life in our galaxy, and renders the Fermi paradox even sharper. Either the Great Filter is ahead of us and there are high risks of anthropogenic extinction, or there are many alien civilizations nearby and of the same age as ours—which is itself a global catastrophic risk, as in that case the wave of alien colonization could arrive between 25-500 ky from now. -/- . (shrink)

Humanity may underestimate the rate of natural global catastrophes because of the survival bias (“anthropic shadow”). But the resulting reduction of the Earth’s future habitability duration is not very large in most plausible cases (1-2 orders of magnitude) and thus it looks like we still have at least millions of years. However, anthropic shadow implies anthropic fragility: we are more likely to live in a world where a sterilizing catastrophe is long overdue and could be triggered by unexpectedly small human (...) actions. In the same way, an over-inflated toy balloon, which will soon burst, is very fragile. Anthropic fragility can manifest itself in the higher chances of runaway global warming. It has often been suggested that the Earth's atmosphere remained life-supporting for billions of years by sheer chance. Therefore, the survival bias can be strong. It is also known that Earth-like water worlds could experience transitions into deadly moisture greenhouse (mean T = 65C). This means that relatively small anthropogenic actions could put the climate above an unpredictable tipping point, which could lead to the moisture greenhouse. Thus, it is necessary to carry out urgent geoengineering studies and prepare to prevent an unexpected climate catastrophe. There are three main counterarguments against the existence of the anthropic shadow: self-indication assumption (SIA), past observers and the Gaia hypothesis; we show that they fail. It was proposed that SIA exactly compensates the anthropic shadow as an observer unlikely to find herself in a world with a strong anthropic shadow; however, there is a baseline level of the anthropic shadow for all habitable planets, similar to the rate of evolutionary transitions like abiogenesis. There are no “past observers” as qualified observers appeared only 50 years ago. Gaia hypothesis assumes existence of self-stabilizing feedback in climate, but new types of events like quick CO2 growth could override its coping ability. We present a list of other catastrophes that may have been underestimated because of the anthropic shadow, including collider catastrophes, nuclear war and even an alien invasion. We also hypothesized that human intelligence is more likely to emerge in an unstable world that is nearing its end and thus we get a new form of Doomsday argument. (shrink)

It is not that scientists make an hypothesis first, and then try to find the data to fit that hypothesis. Rather, the process is first observation, then an hypothes is made to describe the data, then conclude that the data has been described by the hypothesis. But this is not an explanation of the phenomenon. It is merely a description of the data in different terms, usually mathematics. It is essentially a tautology. Thus to observe various points and connect them (...) by a line or curve, then to find the mathematical formula that will construct that curve is said to be the law of the curve or the law governing the data points. If those data points happen to be the positions of a planet in space at different times, then the mathematical equation that produces the points on that curve is called the law of motion of the planets. Now, in origin of life studies, observation reveals that life comes from life only. There is no evidence whatsoever to indicate that life is produced out of non-living matter. It was Louis Pasteur who disproved this theory of abiogenesis. From a purely empirical viewpoint, therefore, we have no justification for stating that life comes from inanimate matter. The evidence is that throughout the entire history of modern science such a production of life from matter has never been observed. The question is: Why make a hypothesis about something that has never been observed? If we want to be scientific, then our hypothesis must match the data. Life comes from life is observed all over the Earth, and we might say, all over the universe as far as we have observed it. So where is the justification for claiming otherwise? Rather, we must conclude that the claim that life comes from matter is completely unscientific because it is not a conclusion based on any empirical observation at all. It is purely wishful thinking — a “naturalistic” or materialistic ideology that is masquerading as science. It is thus doubly deceitful since it is not only an unproven belief but an ideology that poses as a scientific theory. (shrink)

Gregor Mendel (1822-1884) was the first to explain that certain 'traits' were inherited in plants from one generation to the next. These would later become known as genes. Frederich Miescher in 1869 analyzed a substance from the nucleus of cells, which he therefore called nuclein. Further study of nuclein revealed that it contained elements like hydrogen, oxygen, nitrogen and phosphorous, with a specific ratio of nitrogen to phosphorous. Then in 1878 Albrecht Kossel determined that nuclein contained nucleic acid, from which (...) he isolated five nucleobases (nitrogen compounds now referred to by the letters C, G, A, T, U representing cytosine, guanine, adenine, thymine, and uracil). It was also discovered that ribose, a sugar was present in the nuclein compound. What Miescher had isolated from the cell nucleus was actually what would latter be identified as DNA (Deoxyribonucleic acid). C. H. Waddington (1905 - 1975) first proposed the term “epigenetics” in 1942 to describe the region between the gene and the whole organism (phenotype) [3]. Today, what is called the epigenome refers to all the chromosomal modifications, DNA modifications, chromatin protein modifications and their complexes. It is the epigenome that determines both the expression of the genes and their inheritance. R. A. Jorgenson reports [4], "Many of these modifications appear to be “programmable” and to be “read out” to influence chromosomal functions." Nobel laureate Barbara McClintock stated this revolutionary proposal more clearly in her Nobel lecture [5], “to determine the extent of knowledge the cell has of itself, and how it utilizes this knowledge in a ‘thoughtful’ manner when challenged.” In 1960 R. A. Brinks suggested that chromosomes possess a paragenetic function in addition to their genetic function [7]. The physical nature of the paragenetic function is characterized by the variety of forms or states of chromatin that can reside at any genetic locus. While the genetic function is stable, the paragenetic function is labile and programmable in ontogeny. It is this latter function that allows organisms to transfer informational macromolecules (RNA and proteins) in a systematic and regulated manner over what is known as the “RNA information superhighway.” Given this capacity, organisms may be able to store information at numerous genetic loci in the form of paragenetic chromatin states, which can be reprogrammed during ontogeny or environmental stress [8]. This reprogrammable system could operate over the whole organism as a storage device, allowing it to make informed ‘decisions' during growth and development, or in response to the environment. Such processing capacity could be considered a form of ‘intelligence,' which also could be passed on to future generations. The study of the flow of information within and between cells and organisms represents the cutting edge of modern biological research. While physical correlates of cognitive behavior in living organisms are being discovered, it does not spell reduction to such correlates. The electronic activity within the physical components of a radio, for example, may be minutely determined, but ultimately it is not merely the electrical activity that produces the intelligent speech that is heard. Only the intelligent person whose voice is being broadcast through the radio can explain that. Without the broadcaster, the radio would sit silently even though fully functional. An organism without its living agency also appears to be devoid of metabolic activity although all the chemical components are fully present. How to connect life to matter will be the ultimate challenge that has to be met. This will prove to be a philosophical problem we hope to address in the near future. (shrink)