Objective: The coronoid fossa and the olecranon fossa located on the distal end of the humerus are separated by a thin bone septum. This septum may be translucent or opaque. In some cases, this septum may become perforated, and it is called supratrochlear foramen. The aim of the present study was to describe the morphology of the supratrochlear foramen of the humerus. Methods: This study was conducted on 108 dry humeri (right (R): 56, left (L): 52) belonging to adults whose (...) age, gender, and racial properties are unknown. They were examined to determine the presence of the supratrochlear foramen. The shapes of the supratrochlear foramen were determined, and their diameters were measured. Results: The supratrochlear foramen was observed in 11 cases on the right side and 11 cases on the left side. On the right side, 5 foramens were detected to be round-shaped, 3 oval-shaped, and 3 kidney-shaped, whereas on the left side, 6 foramens were detected to be oval-shaped and 5 round-shaped. Of the 86 dry humeri with no supratrochlear foramen, 57 (R: 30, L: 27) had a translucent septum, and 29 (R: 15, L: 14) had an opaque septum. Conclusion: It is apparent that the supratrochlear foramen has been evaluated on bones generally in the literature, and there are differences in incidence rates. Owing to the clinical significance of this formation, it is thought that studying on a wider population of living individuals using radiologic imaging methods will contribute to the literature. In addition, although there are different terms used to express this formation in the literature, it is thought that adopting the name, which is commonly used as supratrochlear foramen, is most appropriate. (shrink)

Because psychological studies of attention and cognition are most commonly performed within the strict confines of the laboratory or take cognitively impaired patients as subjects, it is difficult to be sure that resultant models of attention adequately account for the phenomenon of effortless attention. The problem is not only that effortless attention is resistant to laboratory study. A further issue is that because the laboratory is the most common way to approach attention, models resulting from such studies are naturally the (...) most widely propagated, these models naturally tend to be biased toward features of attention most amenable to laboratory study, and these models by their implications set the agenda for future study that leads back to the laboratory. In this self-reinforcing system, features of attention not amenable to laboratory study are naturally neglected by researchers. In this chapter, I suggest an alternative model of attention as a heuristic for opening paths to further profitable research. The features of attention emphasized in this model are not new, but the synthesis is novel and sheds some light on issues relevant to the topic of effortless attention. I begin with the five following observations: -/- 1. One naturally pays attention to a task of current interest. 2. There are (at least) two distinct modes of attention—selective and diffuse. 3. Attention is a constantly shifting avenue for the assimilation of information. 4. Information is not forced in from outside but is captured through internal sensitization. 5. Human information processing is fundamentally syntactic. -/- Combining these five observations yields an explanatory model of attention that is not only consistent with the data from the many studies on attention in recent decades but also allows us to investigate the neglected phenomenon of effortless attention. The model relies on the notions of apertures, draw, and syntax and is explicated by addressing each of the above observations in turn. In the final part of the chapter, I explore how the model expands our understanding of effortless attention. (shrink)

In formal epistemology, we use mathematical methods to explore the questions of epistemology and rational choice. What can we know? What should we believe and how strongly? How should we act based on our beliefs and values? We begin by modelling phenomena like knowledge, belief, and desire using mathematical machinery, just as a biologist might model the fluctuations of a pair of competing populations, or a physicist might model the turbulence of a fluid passing through a small aperture. Then, (...) we explore, discover, and justify the laws governing those phenomena, using the precision that mathematical machinery affords. For example, we might represent a person by the strengths of their beliefs, and we might measure these using real numbers, which we call credences. Having done this, we might ask what the norms are that govern that person when we represent them in that way. How should those credences hang together? How should the credences change in response to evidence? And how should those credences guide the person’s actions? This is the approach of the first six chapters of this handbook. In the second half, we consider different representations—the set of propositions a person believes; their ranking of propositions by their plausibility. And in each case we ask again what the norms are that govern a person so represented. Or, we might represent them as having both credences and full beliefs, and then ask how those two representations should interact with one another. This handbook is incomplete, as such ventures often are. Formal epistemology is a much wider topic than we present here. One omission, for instance, is social epistemology, where we consider not only individual believers but also the epistemic aspects of their place in a social world. Michael Caie’s entry on doxastic logic touches on one part of this topic, but there is much more. Relatedly, there is no entry on epistemic logic, nor any on knowledge more generally. There are still more gaps. These omissions should not be taken as ideological choices. This material is missing, not because it is any less valuable or interesting, but because we v failed to secure it in time. Rather than delay publication further, we chose to go ahead with what is already a substantial collection. We anticipate a further volume in the future that will cover more ground. Why an open access handbook on this topic? A number of reasons. The topics covered here are large and complex and need the space allowed by the sort of 50 page treatment that many of the authors give. We also wanted to show that, using free and open software, one can overcome a major hurdle facing open access publishing, even on topics with complex typesetting needs. With the right software, one can produce attractive, clear publications at reasonably low cost. Indeed this handbook was created on a budget of exactly £0 (≈ $0). Our thanks to PhilPapers for serving as publisher, and to the authors: we are enormously grateful for the effort they put into their entries. (shrink)

This essay considers how scholarly approaches to the development of molecular biology have too often narrowed the historical aperture to genes, overlooking the ways in which other objects and processes contributed to the molecularization of life. From structural and dynamic studies of biomolecules to cellular membranes and organelles to metabolism and nutrition, new work by historians, philosophers, and STS scholars of the life sciences has revitalized older issues, such as the relationship of life to matter, or of physicochemical inquiries (...) to biology. This scholarship points to a novel molecular vista that opens up a pluralist view of molecularizations in the twentieth century and considers their relevance to current science. (shrink)

Objective: The aim of this study is to evaluate relationship between ostiomeatal complex variations (OMC) and maxillary sinus pathologies in children and adolescents using cone-beam computed tomography (CBCT). -/- Methods: CBCT images of 72 patients (44 males and 28 females) aged 7-18 years were evaluated retrospectively. Presence of nasal septal deviation (NSD), nasal septal pneumatization (NSP), concha bullosa (CB), accessory maxillary ostium (AMO), agger nasi cell (ANC), Haller cell (HC), Onodi cell (OC), ethmoid sinusitis and maxillary sinus pathologies (...) were investigated. Maxillary sinus pathologies were classified. Correlations of OMC variations with each other, maxillary sinus pathologies and ethmoid sinusitis were investigated. Chi-square test was used to analyze relationships among variables and distribution of parameters. -/- Results: NSD was determined in 70.8%, NSP in 40.3%, ethmoid sinusitis in 75%, maxillary sinus pathology in 34.8% of images. OMC variations rates were detected as CB 31.3%, AMO 16%, ANC 16%, HC 24.3% and OC 18.8%. The most common maxillary sinus pathology was localized mucosal thickening, with a rate of 15.3% on right and 22.2% on left. Statistically significant differences were determined between almost all OMC variations with each other, and between anatomical variations in OMC with maxillary sinus pathologies except for NSP and AMO (p < 0.05). The presence of ethmoid sinusitis was more common in males (p =0.026). -/- Conclusion: Anatomical variations in OMC had no significant effect on maxillary sinus pathology except for NSP and AMO. Besides, most of anatomical variations in OMC were statistically significantly correlated with each other. CBCT visualization of these variations is important for sinonasal surgery and is an effective method in children and adolescents with low radiation dose and high image quality compared to computed tomography. (shrink)

Despite the seemingly neutral vantage of using nature for widely-distributed computational purposes, neither post-biological nor post-humanist teleology simply concludes with the real "end of nature" as entailed in the loss of the specific ontological status embedded in the identifier "natural." As evinced by the ecological crises of the Anthropocene—of which the 2019 Brazil Amazon rainforest fires are only the most recent—our epoch has transfixed the “natural order" and imposed entropic artificial integration, producing living species that become “anoetic,” made to serve (...) as automated exosomatic residues, or digital flecks. I further develop Gilles Deleuze’s description of control societies to upturn Foucauldian biopower, replacing its spacio-temporal bounds with the exographic excesses in psycho-power; culling and further detailing Bernard Stiegler’s framework of transindividuation and hyper-control, I examine how becoming-subject is predictively facilitated within cognitive capitalism and what Alexander Galloway terms “deep digitality.” Despite the loss of material vestiges qua virtualization—which I seek to trace in an historical review of industrialization to postindustrialization—the drive-based and reticulated "internet of things" facilitates a closed loop from within the brain to the outside environment, such that the aperture of thought is mediated and compressed. The human brain, understood through its material constitution, is susceptible to total datafication’s laminated process of “becoming-mnemotechnical,” and, as neuroplasticity is now a valid description for deep-learning and neural nets, we are privy to the rebirth of the once-discounted metaphor of the “cybernetic brain.” Probing algorithmic governmentality while posing noetic dreaming as both technical and pharmacological, I seek to analyze how spirit is blithely confounded with machine-thinking’s gelatinous cognition, as prosthetic organ-adaptation becomes probabilistically molded, networked, and agentially inflected (rather than simply externalized). (shrink)

The monistic worldview aims at a uniform description of nature based on scientific models. Quantum physical systems are mutually part of the other quantum physical systems. An aperture distributes the subsystems and the wave front in all possible ways. The system only takes one of the possible paths, as measurements show. Conclusion from Bell's theorem: Before the quantum physical measurement, there is no point-like location in the universe where all the information that explains the measurement is available. Distributed information (...) is possible. Movement of the particle and measuring process are deterministic. The oscillation between location uncertainty and momentum uncertainty leads photons to determine their own location at short intervals. The uncertainty principle focuses the systems. The fields of the surrounding matter influence the location of the new formation. The effect of all fields is based on a common mechanism. (shrink)

Importance: Patients with remitted major depressive disorder (MDD) were previously found to display abnormal functional magnetic resonance imaging connectivity (fMRI) between the right superior anterior temporal lobe (RSATL) and the subgenual cingulate cortex and adjacent septal region (SCSR) when experiencing self-blaming emotions relative to emotions related to blaming others (eg, "indignation or anger toward others"). This finding provided the first neural signature of biases toward overgeneralized self-blaming emotions (eg, "feeling guilty for everything"), known to have a key role in (...) cognitive vulnerability to MDD. It is unknown whether this neural signature predicts risk of recurrence, a crucial step in establishing its potential as a prognostic biomarker, which is urgently needed for stratification into pathophysiologically more homogeneous subgroups and for novel treatments. -/- Objective: To use fMRI in remitted MDD at baseline to test the hypothesis that RSATL-SCSR connectivity for self-blaming relative to other-blaming emotions predicts subsequent recurrence of depressive episodes. -/- Design, setting, and participants: A prospective cohort study from June 16, 2011, to October 10, 2014, in a clinical research facility completed by 75 psychotropic medication-free patients with remitted MDD and no relevant comorbidity. In total, 31 remained in stable remission, and 25 developed a recurring episode over the 14 months of clinical follow-up and were included in the primary analysis. Thirty-nine control participants with no personal or family history of MDD were recruited for further comparison. -/- Main outcomes and measures: Between-group difference (recurring vs stable MDD) in RSATL connectivity, with an a priori SCSR region of interest for self-blaming vs other-blaming emotions. -/- Results: We corroborated our hypothesis that during the experience of self-blaming vs other-blaming emotions, RSATL-SCSR connectivity predicted risk of subsequent recurrence. The recurring MDD group showed higher connectivity than the stable MDD group (familywise error-corrected P < .05 over the a priori SCSR region of interest) and the control group. In addition, the recurring MDD group also exhibited RSATL hyperconnectivity with the right ventral putamen and claustrum and the temporoparietal junction. Together, these regions predicted recurrence with 75% accuracy. -/- Conclusions and relevance: To our knowledge, this study is the first to provide a robust demonstration of an fMRI signature of recurrence risk in remitted MDD. Additional studies are needed for its further optimization and validation as a prognostic biomarker. (shrink)

As a philosophical paradigm, differential heterogenesis offers us a novel descriptive vantage with which to inscribe Deleuze’s virtuality within the terrain of “differential becoming,” conjugating “pure saliences” so as to parse economies, microhistories, insurgencies, and epistemological evolutionary processes that can be conceived of independently from their representational form. Unlike Gestalt theory’s oppositional constructions, the advantage of this aperture is that it posits a dynamic context to both media and its analysis, rendering them functionally tractable and set in relation to (...) other objects, rather than as sedentary identities. Surveying the genealogy of differential heterogenesis with particular interest in the legacy of Lautman’s dialectic, I make the case for a reading of the Deleuzean virtual that departs from an event-oriented approach, galvanizing Sarti and Citti’s dynamic a priori vis-à-vis Deleuze’s philosophy of difference. Specifically, I posit differential heterogenesis as frame with which to examine our contemporaneous epistemic shift as it relates to multi-scalar computational modeling while paying particular attention to neuro-inferential modes of inductive learning and homologous cognitive architecture. Carving a bricolage between Mark Wilson’s work on the “greediness of scales” and Deleuze’s “scales of reality”, this project threads between static ecologies and active externalism vis-à-vis endocentric frames of reference and syntactical scaffolding. (shrink)

The questions that have been looming at the thoughts of many African theologians for years have been: How can the Christian faith be made to be at home in Africa, in such a way that it harmo nizes with African beliefs and practices, thus becoming the religion of the African people? What is the relationship between African traditional religion and culture with the Christian faith? Does being a Christian mean that I should distance myself from m y traditional religious and (...) cultural heritages? It is from this background that Igwebuike theology emerges as an African theology , posting that effort towards evangelization must begin from the understanding of the African worldview and the incorporation of such in the processes of the communication and learning of the Christian faith. This work presented the theology of African typo logy ( u di, meaning type, kind or nature) within the context of Igwebuike theology , with a view to creating a balance in the midst of the conflicts between Christianity and African religion and culture by connecting the events of the New Testament to events and persons in African traditional religion and culture. This connection is such that the events, persons, realities, etc., in African traditional religion and culture find meaning and fulfillment in the New Testament Scriptures. The Igwebuike theology of u di has created an aperture for further dialogue of culture with faith. It provided a deeper meaning and wider capacity for the application of the concept , ‘typology’. It has contributed to the continuous search for better ways of making the Christian fai th feel at home in Africa, and also making it possible for the redemption of the African culture through its interaction with faith. For the purpose of this study, the Igwebuike theoretical framework , which emphasizes beginning from and valuing what is kno wn, and using what is already known as a stepping stone to get to the unknown , was adopted. (shrink)

"Una Pedagogía del Nosotros" pretende mostrar la esencia de la educación como punto de encuentro, compatible con todas las cosmovisiones. La pedagogía del nosotros invita a habitar la educación con originalidad, pero con un criterio más allá de la propia originalidad. Se trata de tener sensibilidad ante el peligro de manipulación, pero también ante el peligro de no educar, por temor a manipular. Los grandes problemas de la Humanidad no se producen por conflictos y crisis, sino por el egocentrismo. Las (...) dificultades, errores, debilidades, conflictos y crisis son humanos, y cuando se gestionan con nosicentrismo, suponen una oportunidad para crecer, pero si se gestionan con egocentrismo, no solo no se resuelven, sino que se agravan, y si se logra un equilibrio de egocentrismos que aporte apariencia de paz, en el fondo, no hay autorrealización porque los sujetos no están sabiendo madurar; simplemente viven para aplacar a su egocentrismo. El nosicentrismo es la maduración original de sí más allá de sí, que tiende a la autorrealización apoteósica entregándose al nosotros-maduro. Para que las comunidades sean vivencias de “nosotros” felices, es primordial que los sujetos se dispongan de forma nosicéntrica en cuerpo, mente y apertura. Cultivando el carácter, desarrollando las competencias y madurando la sensibilidad. De este modo, la unidad de sujetos forma un nosotros-maduro donde cada sí-mismo es más sí-mismo desplegándose hacia fuera, colaborando, sirviendo o dándose sin devorar y sin dejarse devorar. Es un salir para dar o darse, de modo que el sujeto se hace grande haciendo grandes a los demás y se enriquece interiormente, enriqueciendo lo otro. Cuando los sujetos desde su egocentrismo forman un nosotros, en realidad es un falso-nosotros. La educación apertural, libera del falsos-nosotros, cicatriza la originalidad y la despliega por medio de una pedagogía del nosotros-maduro. ¿Y cómo se educa la apertura? Aportando motivos por los que vale la pena abrirse, madurando la conciencia y capacitando al sujeto para una libertad consciente. El sentido es clave para dar, para darse y para saber a quién vale la pena darse por entero, por qué y para qué. ¿Y cómo descubrir el sentido de darse por entero? La clave está en enseñar a cada sujeto a mirar hacia su propio sentido original, que se encuentra en su conciencia. Y así es como realmente uno se hace original y creativo. La educación apertural no es un forzar hacia fuera “porque es bueno”, sino invitar a buscar hacia dentro para reconocerse en su origen y desplegar el sí-mismo original. Pero el sí-mismo no podrá ser plenamente sí-mismo sin el tú, así que será una educación de comunidad, comenzando por la familia. Desde esta interpretación, la acción educativa tiene mucho de acompañar a cada sujeto en la aventura de conocerse a sí mismo, descubrir su propia originalidad y disponerle para que la despliegue con sensibilidad y empatía. No se tratará de imponer desde fuera, sino invitar a sacar; ayudar a crecer. Desde la pedagogía del nosotros se busca el entendimiento de todas las cosmovisiones y de ellas entre sí, para ayudarnos a madurar y habitar en un nosotros-maduro. Así, se considera que lo más práctico es ir al fondo: ¿Cuál es el fin último de la educación? ¿Cuál es la esencia de la autorrealización máxima a la que puede aspirar un sujeto? Para sintetizar la respuesta, se tomará el concepto “apoteosis” del griego apothéōsis “deificación”, “divinización”, “endiosar”. Según cada cosmovisión, la apoteosis supone “estar en la gloria”, disfrutando del máximo bien, al que cada cual aspirará, según sus prioridades vitales: Placer, Poder, Sentido u Originalidad (se explica en el libro). Sea como fuere la cosmovisión del sujeto, el “tú” endiosa, pero es la propia conciencia la que está llamando a ser “dios” y si no se encuentra en el camino de la apoteosis, siente una especie de vacío interior, como que algo no va bien. No termina de vivir colmado; ni cuando prospera con actividades exitosas, ni en una situación general de bienestar, ni en una actitud vital de servicio a los demás, nada colma. La apoteosis es la máxima autorrealización de un sujeto en el “nosotros” o la mejor realización de la Humanidad como “nosotros total”. La educación apoteósica consiste en ayudar a descubrir o redescubrir, en conciencia, el sabor de las alegrías originales de la vida. La pedagogía del nosotros no plantea ninguna fórmula absoluta para educar ni para vivir. Sencillamente se considera el vivir humano como un vivir-con, que sorprende con descubrimientos constantes. Desde la Pedagogía del nosotros todas las instituciones intermedias: familia, escuela, etc., y la sociedad en su conjunto, contribuyen a la educación de cada sujeto, más o menos egocéntrico y más o menos abierto a la aventura de habitar la vida con mayor conciencia. La Pedagogía del nosotros invita a cada sujeto a que apueste toda su existencia a la exploración y experimentación de lo auténtico. Cada sujeto solo puede crecer y desarrollarse, una vez que ha aprendido a vivir en relación con los demás, a reconocer las posibilidades del espacio entre sus “nosotros”. El medio fundamental es el diálogo al que se ha llamado amor, que es lo que sucede cuando dos sujetos comparten en conciencia, algo o todo de sus vidas al mismo tiempo. Dice Antoine de Saint-Exúpery: "amor no es mirarse el uno al otro, sino mirar los dos en la misma dirección". Este compartir en conciencia es convivir en realidad. Dice Buber: "Toda vida real es reunión" y la sociedad, la familia y la escuela tienen la llave para reunirnos y enseñarnos a dialogar. Solo se vive la vida real, la vida auténtica desde la originalidad compartida, cohabitada. Ahí es donde los sujetos pueden ser más sí mismos, creativos y auténticamente felices. (shrink)

Myocardial geometric remodeling is a response to increased stress which includes increased afterload situations during clinical conditions. In this review, we have focused on early and late geometric features in aortic stenosis, importance of recognition of these findings and consequences due to progression of valve disease. We have also pointed out the similarities in early focal and global myocardial geometric remodeling in acute and chronic conditions as hypertension and acute stress cardiomypathy which are associated with myocardial functional and geometric response (...) to acute or chronic stress exposure and relevant increased afterload. In aortic stenosis, target organ involvement in disease progression has been evaluated and discussed in the report. In addition to quantitative evaluation of valve disease, importance of myocardial involvement and global assessment of patients with aortic stenosis also have been mentioned in the report. Finally, we have discussed the importance of global myocardial geometric changes and timing for surgery before development of heart failure in this specific group of patients. (shrink)

The paper is focused on the intedermination in compositive processes. In particular on John Cage. The art and the thought of Cage were a response to the growing complexity of the world through a practice and a reflection that focuses heavily on the concept of emptiness, understood as technical decentralization of: the author of the musical structure and the individual and of the same identification of sounds. This complexity results from a network of independent nodes, subjects, activities and institutions that (...) interact in no particular order. You can no longer assume the existence of an ultimate subject for whose wisdom assumes all sense. There is no longer any author. Events happen randomly. Relinquishing control is one of the main themes running through the compositional work of Cage. (shrink)