Kuhn (1962) proposed an evolutionary model to explain how scientific knowledge is built, based on the concept of paradigm. Even though Kuhn’s model is general, it has been applied to only a few topics in evolutionary biology, almost exclusively to broad-based paradigms. We analyze here, through the lens of Kuhn’s theory, a small-scale paradigm change that occurred with the resolution of the controversy about the mating system of a Mediterranean shrub Phillyrea angustifolia (Oleaceae). We first summarize the different steps of (...) the paradigm change and replace them in the more general context of sex ratio theory. Second, we show how the different steps of the paradigm change can be interpreted by Kuhnian concepts and tools. Finally, we discuss the actual and future status of the new paradigm. (shrink)

This article argues that historical epistemology offers the history of philosophy and science more than a mere tool to write the history of concepts. It does this, first of all, by rereading historical epistemology through Michel Foucault's “techniques of the self.” Second, it turns to the work of Léon Brunschvicg and Gaston Bachelard. In their work we see a proposal for what the subjectivity of scientists and philosophers should be. The article thus argues that their work is driven by a (...) normative psychology: a set of prescriptions for which mental constitution a scholarly self has to have. In the Conclusion, it returns to existing analyses of “open‐mindedness” as a virtue and explores in what way these cases challenge these analyses, as well as to what extent Foucault's “techniques of the self” can be applied to other cases in the history of French philosophy. (shrink)

Raymond Aron was a student of Léon Brunschvicg, a representative of French historical epistemology. This article explores Aron’s relation to this tradition through three claims. First of all, it contests that Raymond Aron’s philosophy of history constituted a complete break with this tradition. Secondly, resituating Aron in this tradition is valuable, because it highlights how Aron’s own philosophy of history is to be understood as a normative project, seen as an alternative to that of Brunschvicg. Finally, Aron’s philosophy can still (...) hold valuable lessons for present-day historical epistemology and history and philosophy of science in general. (shrink)

This essay—a contribution to the Common Knowledge symposium on contextualism—is concerned with the gradual rise of awareness of the existence of modes of thought or systems of belief that are different from those that are dominant in one's own culture. The awareness can be found in the seventeenth and eighteenth centuries but was developed further in the early to mid-twentieth century. Its main consequence has been to encourage individuals to distance themselves from their own system—to criticize and change it.

In Seminar XVII, entitled The reverse side of psychoanalysis, Jacques Lacan presents his famous theorem of the four discourses. In this rereading I propose to demonstrate that Lacan’s theorem entails a transferable dialectical method for studying processes of knowledge production, enabling contemporary scholars to develop a diagnostic of the present, notably scholars interested in issues such as the vicissitudes of knowledge production under capitalism, the crisis of the university and the proliferation of electronic gadgets. In short, I will argue that (...) Lacan’s theorem of the four discourses entails a dialectical diagnostic of technoscientific knowledge during late capitalism. First, the four discourses will be briefly outlined, emphasising the extent to which they entail, albeit in an ambivalent manner, a return or detour to the logic of Hegel. Subsequently, each discourse will be presented in more detail, emphasising how they allow us to come to terms with the current status of technoscientific knowledge. Special attention will be given to the political backdrop of the seminar: the crisis of the university. Finally, I will discuss the historical dimension, outlining both the predecessor of the four discourses and their current predicament under neoliberal/capitalist conditions. (shrink)

Gaston Bachelard occupies a unique position in the history of European thinking. As a philosopher of science, he developed a profound interest in genres of the imagination, notably poetry and novels. While emphatically acknowledging the strength, precision and reliability of scientific knowledge compared to every-day experience, he saw literary phantasies as important supplementary sources of insight. Although he significantly influenced authors such as Lacan, Althusser, Foucault and others, while some of his key concepts are still widely used, his oeuvre tends (...) to be overlooked. And yet, as I will argue, Bachelard’s extended series of books opens up an intriguing perspective on contemporary science. First, I will point to a remarkable duality that runs through Bachelard’s oeuvre. His philosophy of science consists of two sub-oeuvres: a psychoanalysis of technoscience, complemented by a poetics of elementary imagination. I will point out how these two branches deal with complementary themes: technoscientific artefacts and literary fictions, two realms of human experience separated by an epistemological rupture. Whereas Bachelard’s work initially entails a panegyric in praise of scientific practice, he becomes increasingly intrigued by the imaginary and its basic images, such as the Mother Earth archetype. (shrink)

This paper analyses the technoscientific objective of building a synthetic cell from a Jungian perspective. After decades of fragmentation and specialisation, the synthetic cell symbolises a turn towards restored wholeness, both at the object pole and at the subject pole. From a Jungian perspective, it is no coincidence that visual representations of synthetic cells often reflect an archetypal, mandala-like structure. As a symbol of restored unity, the synthetic cell mandala compensates for technoscientific fragmentation via active imagination, providing a visual aid (...) for the technoscientific turn towards reintegration. Although the biotechnological desire to reconstruct life in vitro has been compared to alchemy before, a Jungian analysis allows us to make this comparison more specific and precise. The problem of archetypal images, however, is that alluring prospects of reintegration may underestimate and obfuscate the deficiencies and tensions at work in the current situation. As a projection of a future wholeness, it fosters optimism, but may also function as a misleading façade, covering up collisions and complexities. This can be averted by the conscious employment of the mandala as a symbolic scaffold fostering processes of individuation and working through. (shrink)

In recent years, Nietzsche’s views on (natural) science attracted a considerable amount of scholarly attention. Overall, his attitude towards science tends to be one of suspicion, or ambivalence at least. My article addresses the “Nietzsche and science” theme from a slightly different perspective, raising a somewhat different type of question, more pragmatic if you like, namely: how to be a Nietzschean philosopher of science today? What would the methodological contours of a Nietzschean approach to present-day research areas (such as neuroscience, (...) astrophysics, synthetic biology or climate studies) amount to? In other words, my paper reflects a shift of focus from author studies to extrapolation. The design of my article is as follows. I will start with the question (already widely discussed in the expert literature) to what extent Friedrich Nietzsche (a classical philologist by training) managed to familiarise himself with the natural sciences of his epoch. Subsequently, I will outline some basic methodological and conceptual ingredients of Nietzsche’s philosophy of science, focussing on core issues such as “genealogy”, “interpretation”, “enhancement” and “truth”. Next, I will elucidate Nietzsche’s genealogical methodology with the help of three case studies (three representative samples if you will) taken from Nietzsche’s writings and dealing with physiology, astronomy and neuro-psychology respectively. Finally, I will present the methodological contours of a Nietzschean understanding of contemporary technoscience. (shrink)

The work of Gaston Bachelard is known for two crucial concepts, that of the epistemological rupture and that of phenomenotechnique. A crucial question is, however, how these two concepts relate to one another. Are they in fact essentially connected or must they be seen as two separate elements of Bachelard’s thinking? This paper aims to analyse the relation between these two Bachelardian moments and the significance of the concept of phenomenotechnique for today. This will be done by examining how the (...) concepts of Bachelard have been used from the 1960s on. From this historical perspective, one gets the impression that these two concepts are relatively independent from each other. The Althusserian school has exclusively focused on the concept of ‘epistemological break’, while scholars from Science & Technology Studies, such as Bruno Latour, seem to have only taken up the concept of phenomenotechnique. It in fact leads to two different models of how to think about science, namely the model of purification and the model of proliferation. The former starts from the idea that sciences are rational to the extent that they are purified and free from obstacles. Scientific objectivity, within this later model, is not achieved by eradicating all intermediaries, obstacles and distortions, but rather exactly by introducing as many relevant technical mediators as possible. Finally, such a strong distinction will be criticized and the argument will be made that both in Bachelard’s and Latour's thought both concepts are combined. This leads to a janus-headed view on science, where both the element of purification and the element of proliferation are combined. (shrink)

This paper addresses the cultural impact of genomics and the Human Genome Project on human self-understanding. Notably, it addresses the claim made by Francis Collins that the genome is the language of God and the claim made by Max Delbrück that Aristotle must be credited with having predicted DNA as the soul that organises bio-matter. From a continental philosophical perspective I will argue that human existence results from a dialectical interaction between two types of texts: the language of molecular biology (...) and the language of civilisation; the language of the genome and the language of our socio-cultural, symbolic ambiance. Whereas the former ultimately builds on the alphabets of genes and nucleotides, the latter is informed by primordial texts such as the Bible and the Quran. In applied bioethics deliberations on genomics, science is easily framed as liberating and progressive, religious world-views as conservative an... (shrink)

This monograph contributes to the scientific misconduct debate from an oblique perspective, by analysing seven novels devoted to this issue, namely: Arrowsmith by Sinclair Lewis (1925), The affair by C.P. Snow (1960), Cantor’s Dilemma by Carl Djerassi (1989), Perlmann’s Silence by Pascal Mercier (1995), Intuition by Allegra Goodman (2006), Solar by Ian McEwan (2010) and Derailment by Diederik Stapel (2012). Scientific misconduct, i.e. fabrication, falsification, plagiarism, but also other questionable research practices, have become a focus of concern for academic communities (...) worldwide, but also for managers, funders and publishers of research. The aforementioned novels offer intriguing windows into integrity challenges emerging in contemporary research practices. They are analysed from a continental philosophical perspective, providing a stage where various voices, positions and modes of discourse are mutually exposed to one another, so that they critically address and question one another. They force us to start from the admission that we do not really know what misconduct is. Subsequently, by providing case histories of misconduct, they address integrity challenges not only in terms of individual deviance but also in terms of systemic crisis, due to current transformations in the ways in which knowledge is produced. Rather than functioning as moral vignettes, the author argues that misconduct novels challenge us to reconsider some of the basic conceptual building blocks of integrity discourse. (shrink)

This article deals with some aspects of the study of the mind between the 1920s and 1940s at the University of Paris. Traditionally the domain of philosophy, the study of the mind was encroached upon by other disciplines such as history of science, ethnology, sociology and psychology. These disciplines all had weak institutional status and were struggling to constitute themselves as autonomous. History of science did not as a rule reject its relationship with philosophy, whereas ethnology, sociology and psychology were (...) constructing their identities by breaking away from philosophy. A discussion about Lévy-Bruhl’s La mentalité primitive, hosted by the Société Française de Philosophie in 1923, showed that the positions of philosophers, sociologists and psychologists about the questions posed by the book, namely the fixity and universality of the mind, were strictly linked with their views about the ‘scientificity’ of ethnology. A compromise between fixity and historical transformation of the mind was put forward by Gaston Bachelard, who institutionally represented the discipline of history and philosophy of science. This discipline was institutionally linked to ethnology, psychology and sociology, but, unlike them, had no claim to ‘scientificity’. Bachelard realized this compromise by breaking the unity of the mind and by employing an extra-institutional discipline: psychoanalysis. His freedom of choice corresponded with an increasingly weak institutional position for the discipline of history and philosophy of science. (shrink)

In this paper, I will reread the history of molecular genetics from a psychoanalytical angle, analysing it as a case history. Building on the developmental theories of Freud and his followers, I will distinguish four stages, namely: (1) oedipal childhood, notably the epoch of model building (1943–1953); (2) the latency period, with a focus on the development of basic skills (1953–1989); (3) adolescence, exemplified by the Human Genome Project, with its fierce conflicts, great expectations and grandiose claims (1989–2003) and (4) (...) adulthood (2003–present) during which revolutionary research areas such as molecular biology and genomics have achieved a certain level of normalcy—have evolved into a normal science. I will indicate how a psychoanalytical assessment conducted in this manner may help us to interpret and address some of the key normative issues that have been raised with regard to molecular genetics over the years, such as ‘relevance’, ‘responsible innovation’ and ‘promise management’. (shrink)

This discussion paper proposes that a meaningful distinction between science and technoscience can be found at the level of the objects of research. Both notions intermingle in the attitudes, intentions, programs and projects of researchers and research institutions—that is, on the side of the subjects of research. But the difference between science and technoscience becomes more explicit when research results are presented in particular settings and when the objects of research are exhibited for the specific interest they hold. When an (...) experiment is presented as scientific evidence which confirms or disconfirms a hypothesis, this agrees with traditional conceptions of science. When organic molecules are presented for their capacity to serve individually as electric wires that carry surprisingly large currents, this would be a hallmark of technoscience. Accordingly, we propose research on the ontology of research objects. The focus on the character and significance of research objects makes this a specifically philosophical project. (shrink)

Le mathématicien au travail sait faire un geste que l'on appelle la« pulsation mathématique», qui s'exprime en tennes de bougé créatif nécessaire dans les diagrammes de pensée et d'interprétation des écrits mathématiques. Dans cette perspective Je statut d'objet est définitivement en révision, sous condition du jeu des relations. Le but ici est de construire aujourd'hui cette pulsation à partir de ce que Bachelard proposait hier comme épistémologie, aussi bien de la mathématique que de la science dite physique mathématique. Les liens (...) entre la pensée bachelardienne et les propositions plus récentes de Gilles Châtelet, Charles Alunni, ou René Guitart, sont mis en relief ainsi que ceux d'autres auteurs comme Jacques Lacan, Arthur Koestler, Alfred N. Whitehead, Charles S. Peirce. Nous proposons que le travail mathématique soit pensable comme du mouvement dans l'espace des diagrammes, du bougé pulsatif en icelui, et que cette manière de voir soit éminemment compatible avec la vue bacheJardienne suivant laquelle la forme intellectuelle précède l'objet empirique, lequel provient in fine, comme d'une concrétion de la pulsation de la pensée. Nous terminons donc sur un schème catégoricien de la pulsation. (shrink)

This article provides an overview of the historical and philosophical context from which originated G. Bachelard's concept of "phenomenotechnique". It analyzes why phenomenotechnique is crucial for science studies. By incorporating the concept of phenomenotechnique into Hacking's and Galison's models of science, I argue that we can avoid the radicalism of both while also preventing the analysis of scientific practices from collapsing into the interpretive frames mandated by social constructivists.

According to a defense of scientific realism known as the “divide et impera move”, mature scientific theories enjoying predictive success are partially true. This paper investigates a paradigmatic historical case: the prediction, based on Fresnel’s wave theory of light, that a bright spot should figure in the shadow of a disc. Two different derivations of this prediction have been given by both Poisson and Fresnel. I argue that the details of these derivations highlight two problems of indispensability arguments, which state (...) that only the indispensable constituents of this success are worthy of belief and retained through theory-change. The first problem is that, contrary to a common claim, Fresnel’s integrals are not needed to predict the bright spot phenomenon. The second problem is that the hypotheses shared by to these two derivations include problematic idealizations. I claim that this example leads us to be skeptical about which aspects of our current theories are worthy of belief. (shrink)

Buddhism has always produced epistemological systems, and those of the Mahāyāna, in particular, always showed knowledge and perception to be inherently delusive. “Higher” forms of Buddhism have a degenerative philosophy of history according to which a sort of Golden Age was disrupted by the rise and gradual development of knowledge and the delusion inherent in it, which have reached their apex in our time – the final phase of the “Era of Darkness.” From this standpoint, this paper intends to show (...) science, in which Marcuse saw an inherent instrumental/technological interest, to have been developed by delusion and to have simultaneously furthered the development of delusion, to the point at which they begot the deadly ecological crisis proper to this concluding phase of the Era of Darkness – which reveals as such the delusion at its root, achieving the latter’s empirical reductio ad absurdum and offering us the possibility of eradicating it and thus healing our minds and, hopefully, our world. (shrink)

Since the Enlightenment critique has played an overarching role in how western society understands itself and its basic institutions. However, opinions differ widely concerning the understanding and evaluation of critique. To understand such differences and clarify a viable understanding of critique, the article turns to Kant’s critical philosophy, inaugurating the “age of criticism”. While generalizing and making critique unavoidable, Kant coins an unambiguously positive understanding of critique as an affirmative, immanent activity. Not only does this positive conception prevail in the (...) critique of pure and practical reason and the critique of judgment; these modalities of critique set the agenda for three major strands of critique in contemporary thought, culminating in among others Husserl, Popper Habermas, Honneth, and Foucault. Critique affirms and challenges cognition and its rationality, formulates ethical ideals that regulate social interaction, and further articulates normative guidelines underway in the on-going experimentations of a post-natural history of human nature. In contradistinction to esoteric Platonic theory, philosophy at the threshold of modernity becomes closely linked to an outward-looking critique that examines and pictures what human forms of life are in the process of making of themselves and challenges them, by reflecting upon what they can and what they should make of themselves. As a very widely diffused practice, however, critique may also become a self-affirming overarching end in itself. (shrink)

In inter-war France, history of philosophy was a very important academic discipline, but nevertheless its practitioners thought it necessary to defend its identity, which was threatened by its vicinity to many other disciplines, and especially by the emergent social sciences and history of science. I shall focus on two particular issues that divided traditional historians of philosophy from historians of science, ethnologists and sociologists, and that became crucial in the definition of the identity of their disciplines: the conception of history (...) and the interpretation of texts. By analysing representative discussions and positions, I shall show that traditional historians of philosophy needed to reassert their own approach to history, which, borrowing the term from Bergson, I define as ‘snapshot’. This approach is focused on a particular idea or text rather than a narrative. I shall also show that history of philosophy, in its traditional form, would have been undermined both intellectually and institutionally by the opposite ‘narrative’ approach of history of science and of the social sciences. Social scientists openly attacked history of philosophy’s methods and, in the eyes of traditional philosophers, its existence as an academic discipline. The same opposition is to be found in evaluation of past texts, which for traditional historians of philosophy were to be read as timeless documents, while for historians of science, ethnologists and sociologists were to be considered as documents exhibiting a particular mentality. However, between these alternatives there were intermediate positions. I shall in particular consider that of Léon Brunschvicg: he embraced a narrative approach and considered texts as documents of different ways of thinking, but at the same time carried on employing philosophical methods and defending the institutional position of philosophy. I shall argue that this was possible partly because of the considerable amount of power he enjoyed at the Sorbonne. (shrink)

In this article I assess Georges Canguilhem's historical epistemology with both theoretical and historical questions in mind. From a theoretical point of view, I am concerned with the relation between history and philosophy, and in particular with the philosophical assumptions and external norms that are involved in history writing. Moreover, I am concerned with the role that history can play in the understanding and evaluation of philosophical concepts. From a historical point of view, I regard historical epistemology, as developed by (...) Gaston Bachelard and Georges Canguilhem, as a conception and practice which came out of the project, elaborated in France from the 1920s to the 1940s, of combining history of science and philosophy. I analyse in particular Canguilhem's epistemology in his theory and practice of history of science. What he called 'normative history' is the focus of my analysis. I evaluate the question of the nature and provenience of the norm employed in normative history, and I compare it with the norm as discussed by Canguilhem in Le normal et le pathologique. While I am critical of Canguilhem's treatment of history, I conclude that his philosophical suggestion to analyse the formation of scientific concepts 'from below' represents a useful model for history and philosophy of science, and that it can be very profitably extended to philosophical concepts. (shrink)

Problem setting. The structure of the legal life phenomenological model, alongside the social experience and legal values, always contains subjective measurements that reflect legal person’s specific features. In particular, the point is in the legal duties, powers and the capability of legal reasoning. Their consideration provides an opportunity to show the integral phenomenological model of law via restored bonds of all its elements, and also enables us to extend the semantic field of social-philosophical aspect of the research through creating theoretical (...) pre-conditions for studying burning issues and specific manifestations of the modern law. Recent research and publications analysis. In phenomenology the person is traditionally recognized as the essential being, while the process of sense generation ensures, inter alia, contextual opportunities to study law. The contemporary experience of the legal person phenomenological understanding may be complemented by the research into the abilities of the legal person as an element of the legal life phenomenological model. Paper aim. This work aims to study the features of the legal person as a structural element of the legal life phenomenological model. Paper results and discussion. The paper shows that the law lifeworld is deeply rooted in social experience. It confirms that owing to the legal person the law lifeworld is constituted and “extended” with interpretations. Its activity as to the given social experience provides grounds to declare the equality of the following modalities: “be the carrier of legal awareness”, “be a legal agent” and “be a recognized and legally protected value”. These theoretical statements enable us to formulate certain social-philosophical issues of legal standing, and outline the ways of their solving. For instance, there is a problem of the symbolic status of a legal entity, found in its relations with the state and citizens; the issue of possible legal person’s recognition as a value in the conditions of his/her minimalized rights and hypertrophy of the legal duties is considered; the nature of a legal conflict and the mechanism of its solution is studied through recognizing the value of various communicative perspectives; it is stated that the differences between the intentional experiences of a legal person and the person with duties are a precondition to form legal nihilism and ignorance. The legal person is also considered in the context of his or her ability to be engaged in the discourse practices, embedded in the mechanisms of interpersonal constitution of senses inherent in the social being. The purpose of the legal discourse in the modern world is defined as a field to identify problems and “tension zones” in the implementation of liberal values and the rule of law. Following the analysis of the approaches to identifying the legal discourse core, its main strategies were discussed: legal discourse is focused on searching and developing socially important topics and sound arguments, confirming positive suggestions for the solving social problems (after J. Habermas); legal discourse implies the use of the power of language to fight against the arbitrary rule, including that of the legitimate power (М. Foucault); the specifics of the legal discourse are in creating linguistic tools and developing the procedures, owing to which legal enforcement is transferred to the speech space (P. Ricoeur). Conclusion. The study showed that the activity of the person who has his or her own legal opinion is in the fact that their generated texts and individual statements are not limited to the formal logical regulations, but are the means of expressing their social experience, the measure of balancing between the person’s claims and his or her social recognition. (shrink)

Le mathématicien au travail sait faire un geste que l'on appelle la« pulsation mathématique», qui s'exprime en tennes de bougé créatif nécessaire dans les diagrammes de pensée et d'interprétation des écrits mathématiques. Dans cette perspective Je statut d'objet est définitivement en révision, sous condition du jeu des relations. Le but ici est de construire aujourd'hui cette pulsation à partir de ce que Bachelard proposait hier comme épistémologie, aussi bien de la mathématique que de la science dite physique mathématique. Les liens (...) entre la pensée bachelardienne et les propositions plus récentes de Gilles Châtelet, Charles Alunni, ou René Guitart, sont mis en relief ainsi que ceux d'autres auteurs comme Jacques Lacan, Arthur Koestler, Alfred N. Whitehead, Charles S. Peirce. Nous proposons que le travail mathématique soit pensable comme du mouvement dans l'espace des diagrammes, du bougé pulsatif en icelui, et que cette manière de voir soit éminemment compatible avec la vue bacheJardienne suivant laquelle la forme intellectuelle précède l'objet empirique, lequel provient in fine, comme d'une concrétion de la pulsation de la pensée. Nous terminons donc sur un schème catégoricien de la pulsation. (shrink)

Since the Enlightenment, critique has played an overarching role in how Western society understands itself and its basic institutions. However, opinions differ widely concerning the understanding and evaluation of critique. To understand such differences and clarify a viable understanding of critique, the article turns to Kant’s critical philosophy, inaugurating the “age of criticism”. While generalizing and making critique unavoidable, Kant coins an unambiguously positive understanding of critique as an affirmative, immanent activity. Not only does this positive conception prevail in the (...) critique of pure and practical reason and the critique of judgment; these modalities of critique set the agenda for three major strands of critique in contemporary thought, culminating in among others Husserl, Popper, Habermas, Honneth, and Foucault. Critique affirms and challenges cognition and its rationality, formulates ethical ideals that regulate social interaction, and further articulates normative guidelines underway in the ongoing experimentations of a post-natural history of human nature. In contradistinction to esoteric Platonic theory, philosophy at the threshold of modernity becomes closely linked to an outward-looking critique that examines and pictures what human forms of life are in the process of making of themselves and challenges them, by reflecting upon what they can and what they should make of themselves. As a very widely diffused practice, however, critique may also become a self-affirming overarching end in itself. (shrink)

Roy Bhaskar, Reclaiming Reality: a Critical Introduction to Contemporary Philosophy, London: Verso, 1989, £24.95, paper £8.95, ix + 218 pp.

.The article deals with the difference between some forms of legal positivism. It is argued that, even in continental legal systems which are typically “rule bound,” there is some space left for principles in the legal system. The author tries to explain how this space can be filled and what methods should be used by a judge to do so.

Written in the form of a dialogue with Brussels sociologist Dieter Vandebroeck, this article retraces the social and intellectual trajectory of Loïc Wacquant as stepping stone to reviewing and discussing the major concepts coined and theoretical propositions elaborated in the course of his research on comparative urban marginality, racial domination, the ghetto, the penal state, neoliberalism, and carnality. This provides an opportunity to specify the relationships between ethnography, history and theory; the dialectic of domination and resistance; the role of public (...) (dis)honor in social life; the uses of Bourdieu's bureaucratic field; and the social and academic conditions of incubation, diffusion, and death of scholarly myths such as the “underclass.” The article closes on a call to clearly distinguish the rhetorical, metaphorical, and analytical usages of concepts and reaffirms the need for epistemic reflexivity as sine qua non for the articulation of robust scientific problematics. (shrink)

Since the practice turn, the role technologies play in the production of scientific knowledge has become a prominent topic in science studies. Much existing scholarship, however, either limits technology to merely mechanical instrumentation or uses the term for a wide variety of items. This article argues that technologies in scientific practice can be understood as a result of past scientific knowledge becoming sedimented in materials, like model organisms, synthetic reagents or mechanical instruments, through the routine use of these materials in (...) subsequent research practice. The proposed theoretical interpretation of technology is examined through a case where a model organism—Drosophila melanogaster—acted as a technology for investigating a contested biological effect of a mechanical instrument: Hermann J. Muller’s experiments on X-ray mutagenicity in the 1920s. The article reconstructs how Muller employed two synthetic Drosophila stocks as tests for measuring X-rays’ capacity to cause genetic aberration. It argues that past scientific knowledge sedimented in the Drosophila stocks influenced Muller’s perception of X-ray-induced mutation. It further describes how Muller’s concept of X-ray mutagenicity sedimented through the adoption of X-ray machines as a ready-made resource for producing mutants by other geneticists, for instance George Beadle and Edward Tatum in their experiments on Neurospora crassa, despite ongoing disputes surrounding Muller’s conclusions. Technological sedimentation is proposed as a potential explanation why sedimentation and disputation may often coexist in the history of science. (shrink)