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Explaining the Brain

Oxford, GB: Oxford University Press (2007)

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  1. Mechanisms as Modal Patterns.Joseph Rouse - unknown
    Philosophical discussions of mechanisms and mechanistic explanation have often been framed by contrast to laws and deductive-nomological explanation. A more adequate conception of lawfulness and nomological necessity, emphasizing the role of modal considerations in scientific reasoning, circumvents such contrasts and enhances understanding of mechanisms and their scientific significance. The first part of the paper sketches this conception of lawfulness, drawing upon Haugeland, Lange, and Rouse. This conception emphasizes the role of lawful stability under relevant counterfactual suppositions in scientific reasoning across (...)
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  • Naturalizing the Mind.Marcin Miłkowski & Konrad Talmont-Kamiński - 2013 - In Marcin Miłkowski & Konrad Talmont-Kamiński (eds.), Regarding Mind, Naturally. Cambridge Scholars Press.
    The introduction to the volume and the overview of the idea of naturalizing the mind.
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  • Variedades de la explicación en evo-devo.María Alejandra Petino Zappala & Sergio Daniel Barberis - 2018 - Epistemologia E Historia de la Ciencia 3 (1):18-31.
    The aim of this paper lies in characterizing the explanations and models used in the field of evolutionary developmental biology throughout its history. While manipulative experiments in controlled conditions have been useful to set the bases of the discipline and are still routinely performed, this approach supposes a tension between the reliability and the representativity of the conclusions. Given the recent changes in the understanding of evolutionary phenomena, different authors currently emphasize the need of avoiding excessive simplifications in experimental approaches, (...)
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  • Mechanisms and Laws: Clarifying the Debate.Marie I. Kaiser & C. F. Craver - 2013 - In H.-K. Chao, S.-T. Chen & R. Millstein (eds.), Mechanism and Causality in Biology and Economics. Dordrecht: Springer. pp. 125-145.
    Leuridan (2011) questions whether mechanisms can really replace laws at the heart of our thinking about science. In doing so, he enters a long-standing discussion about the relationship between the mech-anistic structures evident in the theories of contemporary biology and the laws of nature privileged especially in traditional empiricist traditions of the philosophy of science (see e.g. Wimsatt 1974; Bechtel and Abrahamsen 2005; Bogen 2005; Darden 2006; Glennan 1996; MDC 2000; Schaffner 1993; Tabery 2003; Weber 2005). In our view, Leuridan (...)
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  • Rethinking unification : unification as an explanatory value in scientific practice.Merel Lefevere - 2018 - Dissertation, University of Ghent
    This dissertation starts with a concise overview of what philosophers of science have written about unification and its role in scientific explanation during the last 50 years to provide the reader with some background knowledge. In order to bring unification back into the picture, I have followed two strategies, resulting respectively in Parts I and II of this dissertation. In Part I the idea of unification is used to refine and enrich the dominant causalmechanist and causal-interventionist accounts of scientific explanation. (...)
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  • The Ethical Gravity Thesis: Marrian Levels and the Persistence of Bias in Automated Decision-making Systems.Atoosa Kasirzadeh & Colin Klein - 2021 - Proceedings of the 2021 AAAI/ACM Conference on AI, Ethics, and Society (AIES '21).
    Computers are used to make decisions in an increasing number of domains. There is widespread agreement that some of these uses are ethically problematic. Far less clear is where ethical problems arise, and what might be done about them. This paper expands and defends the Ethical Gravity Thesis: ethical problems that arise at higher levels of analysis of an automated decision-making system are inherited by lower levels of analysis. Particular instantiations of systems can add new problems, but not ameliorate more (...)
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  • Psa 2012.-Preprint Volume- - unknown
    These preprints were automatically compiled into a PDF from the collection of papers deposited in PhilSci-Archive in conjunction with the PSA 2012.
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  • Mental Imagery, Emotion, and Literary Task Sets Clues Towards a Literary Neuroart.Federico Langer - 2012 - Journal of Consciousness Studies 19 (7-8):168-215.
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  • Epistemic causality and evidence-based medicine.Federica Russo & Jon Williamson - 2011 - History and Philosophy of the Life Sciences 33 (4).
    Causal claims in biomedical contexts are ubiquitous albeit they are not always made explicit. This paper addresses the question of what causal claims mean in the context of disease. It is argued that in medical contexts causality ought to be interpreted according to the epistemic theory. The epistemic theory offers an alternative to traditional accounts that cash out causation either in terms of “difference-making” relations or in terms of mechanisms. According to the epistemic approach, causal claims tell us about which (...)
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  • Causal webs in epidemiology.Federica Russo - unknown
    The notion of ‘causal web’ emerged in the epidemiological literature in the early Sixties and had to wait until the Nineties for a thorough critical appraisal. Famously, Nancy Krieger argued that such a notion isn’t helpful unless we specify what kind of spiders create the webs. This means, according to Krieger, (i) that the role of the spiders is to provide an explanation of the yarns of the web and (ii) that the sought spiders have to be biological and social. (...)
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  • Natural Selection and Causal Productivity.Roberta L. Millstein - 2013 - In Hsiang-Ke Chao, Szu-Ting Chen & Roberta L. Millstein (eds.), Mechanism and Causality in Biology and Economics,. Springer.
    In the recent philosophical literature, two questions have arisen concerning the status of natural selection: (1) Is it a population-level phenomenon, or is it an organism-level phenomenon? (2) Is it a causal process, or is it a purely statistical summary of lower-level processes? In an earlier work (Millstein, Br J Philos Sci, 57(4):627–653, 2006), I argue that natural selection should be understood as a population-level causal process, rather than a purely statistical population-level summation of lower-level processes or as an organism-level (...)
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  • Wyjaśnianie w kognitywistyce.Marcin Miłkowski - 2013 - Przeglad Filozoficzny - Nowa Seria 86 (2):151-166.
    The paper defends the claim that the mechanistic explanation of information processing is the fundamental kind of explanation in cognitive science. These mechanisms are complex organized systems whose functioning depends on the orchestrated interaction of their component parts and processes. A constitutive explanation of every mechanism must include both appeal to its environment and to the role it plays in it. This role has been traditionally dubbed competence. To fully explain how this role is played it is necessary to explain (...)
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  • When is it Mental?Stuart Glennan - 2015 - Humana Mente 8 (29).
    Most philosophical debate over mental causation has been concerned with reconciling commonsense intuitions that there are causal interactions between the mental and the physical with philosophical theories of the nature of the mental that seem to suggest otherwise. My concern is with a different and more practical problem. We often confront some cognitive, affective, or bodily phenomenon, and wonder about its source – its etiology or its underlying causal basis. For instance, you might wonder whether your queasiness due to something (...)
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  • A pragmatic-ontic account of mechanistic explanation.Daniel Sirtes - unknown
    Craver’s (2007) account of explanation in neurobiology offers one of the most sophisticated explications of the mechanism concept. This paper argues that despite groundbreaking advances in understanding mechanistic explanation, serious challenges remain. The first goal of this paper is to address the notorious problem of explanatory relevance concerning mechanistic explanation. I argue that Craver underestimates the importance of pragmatic constraints on the individuation of mechanisms, and that his suggestion for a solution of the explanatory relevance problem is therefore insufficient on (...)
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  • Methodological Problems on the Way to Integrative Human Neuroscience.Kotchoubey Boris, Tretter Felix, A. Braun Hans, Buchheim Thomas, Draguhn Andreas, Fuchs Thomas, Hasler Felix, Hastedt Heiner, Hinterberger Thilo, Northoff Georg, Rentschler Ingo, Schleim Stephan, Sellmaier Stephan, Van Elst Ludger Tebartz & Tschacher Wolfgang - unknown
    Neuroscience is a multidisciplinary effort to understand the structures and functions of the brain and brain-mind relations. This effort results in an increasing amount of data, generated by sophisticated technologies. However, these data enhance our descriptive knowledge, rather than improve our understanding of brain functions. This is caused by methodological gaps both within and between subdisciplines constituting neuroscience, and the atomistic approach that limits the study of macro- and mesoscopic issues. Whole-brain measurement technologies do not resolve these issues, but rather (...)
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  • Sculpting the space of actions. Explaining human action by integrating intentions and mechanisms.Machiel Keestra - 2014 - Dissertation, University of Amsterdam
    How can we explain the intentional nature of an expert’s actions, performed without immediate and conscious control, relying instead on automatic cognitive processes? How can we account for the differences and similarities with a novice’s performance of the same actions? Can a naturalist explanation of intentional expert action be in line with a philosophical concept of intentional action? Answering these and related questions in a positive sense, this dissertation develops a three-step argument. Part I considers different methods of explanations in (...)
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  • Sensorimotor Laws, Mechanisms, and Representations.Alfredo Vernazzani - 2014 - Proceedings of the 36th Meeting of the Cognitive Science Society.
    According to the sensorimotor account, vision does not imply theconstruction of internally generated representations of the environment, butit isthe skillful exercise of the sensorimotor contingencies obeying sense-specific laws. In this short study, I focus on the notion of “sensorimotor law” and characterize the kind of explanation providedby the sensorimotor theory as a form of covering law model. I then question the nature of such sensorimotor laws and describe them as mechanisms. I show that a mechanistic interpretation provides a better account (...)
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  • Manipulating the Contents of Consciousness.Alfredo Vernazzani - 2015 - Proceedings of the 37th Meeting of the Cognitive Science Society.
    I argue for a manipulationist-mechanistic framework for content-NCC research in the case of visual consciousness (Bechtel 2008; Neisser 2012). Reference to mechanisms is common in the NCC research. Furthermore, recent developments in non-invasive brain stimulation techniques (NIBS) lend support to a manipulationist standpoint. The crucial question is to understand what is changed after manipulation of a brain mechanism. In the second part of the paper I review the literature on intentionalism, and argue that intervention on the neural mechanism is likely (...)
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  • L'explication en biologie.Marie I. Kaiser - 2014 - In F. Merlin & T. Hoquet (eds.), Précis de Philosophie de la biologie [Handbook Philosophy of Biology]. Paris, France: Vuibert Press. pp. 143-155.
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  • The Meta-Explanatory Question.L. R. Franklin-Hall - manuscript
    Philosophical theories of explanation characterize the difference between correct and incorrect explanations. While remaining neutral as to which of these ‘first-order’ theories is right, this paper asks the ‘meta-explanatory’ question: is the difference between correct and incorrect explanation real, i.e., objective or mind-independent? After offering a framework for distinguishing realist from anti-realist views, I sketch three distinct paths to explanatory anti-realism.
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  • Against Explanatory Minimalism in Psychiatry.Tim Thornton - 2015 - Frontiers of Psychiatry 6.
    The idea that psychiatry contains, in principle, a series of levels of explanation has been criticised both as empirically false but also, by Campbell, as unintelligible because it presupposes a discredited pre-Humean view of causation. Campbell’s criticism is based on an interventionist-inspired denial that mechanisms and rational connections underpin physical and mental causation respectively and hence underpin levels of explanation. These claims echo some superficially similar remarks in Wittgenstein’s Zettel. But attention to the context of Wittgenstein’s remarks suggests a reason (...)
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  • The Continuing Relevance of 19th-Century Philosophy of Psychology: Brentano and the Autonomy of Psychological Methods.Uljana Feest - 2014 - In M. C. Galavotti & F. Stadler (eds.), New Directions in the Philosophy of Science, The Philosophy of Science in a European Perspective 5. Springer. Springer. pp. 693-709.
    This paper provides an analysis of Franz Brentano’s thesis that psychology employs a distinctive method, which sets it apart from physiology. The aim of the paper is two-fold: First, I situate Brentano’s thesis (and the broader metaphysical system that underwrites it) within the context of specific debates about the nature and status of psychology, arguing that we regard him as engaging in a form of boundary work. Second, I explore the relevance of Brentano’s considerations to more recent debates about autonomy (...)
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  • Mechanisms and psychological explanation.Cory Wright & William Bechtel - 2007 - In Paul Thagard (ed.), Handbook of the Philosophy of Psychology and Cognitive Science. Elsevier.
    As much as assumptions about mechanisms and mechanistic explanation have deeply affected psychology, they have received disproportionately little analysis in philosophy. After a historical survey of the influences of mechanistic approaches to explanation of psychological phenomena, we specify the nature of mechanisms and mechanistic explanation. Contrary to some treatments of mechanistic explanation, we maintain that explanation is an epistemic activity that involves representing and reasoning about mechanisms. We discuss the manner in which mechanistic approaches serve to bridge levels rather than (...)
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  • Addiction-as-a-kind hypothesis.Petri Ylikoski & Samuli Pöyhönen - 2015 - International Journal of Addiction and Drug Research 4 (1):21-25.
    The psychiatric category of addiction has recently been broadened to include new behaviors. This has prompted critical discussion about the value of a concept that covers so many different substances and activities. Many of the debates surrounding the notion of addiction stem from different views concerning what kind of a thing addiction fundamentally is. In this essay, we put forward an account that conceptualizes different addictions as sharing a cluster of relevant properties (the syndrome) that is supported by a matrix (...)
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  • Causal graphs and biological mechanisms.Alexander Gebharter & Marie I. Kaiser - 2014 - In Marie I. Kaiser, Oliver Scholz, Daniel Plenge & Andreas Hüttemann (eds.), Explanation in the special sciences: The case of biology and history. Dordrecht: Springer. pp. 55-86.
    Modeling mechanisms is central to the biological sciences – for purposes of explanation, prediction, extrapolation, and manipulation. A closer look at the philosophical literature reveals that mechanisms are predominantly modeled in a purely qualitative way. That is, mechanistic models are conceived of as representing how certain entities and activities are spatially and temporally organized so that they bring about the behavior of the mechanism in question. Although this adequately characterizes how mechanisms are represented in biology textbooks, contemporary biological research practice (...)
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  • Making Naturalised Epistemology (Slightly) Normative.Marcin Miłkowski - 2010 - In Konrad Talmont-Kaminski & Marcin Miłkowski (eds.), Beyond Description. Naturalism and Normativity.
    The standard objection against naturalised epistemology is that it cannot account for normativity in epistemology (Putnam 1982; Kim 1988). There are different ways to deal with it. One of the obvious ways is to say that the objection misses the point: It is not a bug; it is a feature, as there is nothing interesting in normative principles in epistemology. Normative epistemology deals with norms but they are of no use in prac-tice. They are far too general to be guiding (...)
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  • Situatedness and Embodiment of Computational Systems.Marcin Miłkowski - 2017 - Entropy 19 (4):162.
    In this paper, the role of the environment and physical embodiment of computational systems for explanatory purposes will be analyzed. In particular, the focus will be on cognitive computational systems, understood in terms of mechanisms that manipulate semantic information. It will be argued that the role of the environment has long been appreciated, in particular in the work of Herbert A. Simon, which has inspired the mechanistic view on explanation. From Simon’s perspective, the embodied view on cognition seems natural but (...)
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  • The power of possible causation.Phil Dowe - unknown
    In this paper I consider possible causation, specifically, would-cause counterfactuals of the form ‘had an event of kind A occurred, it would have caused an event of kind B’. I outline some difficulties for the Lewis program for understanding would-cause counterfactuals, and canvass an alternative. I then spell out a view on their significance, in relation to (i) absence causation, where claims such as ‘A’s not occurring caused B’s not occurring’ seem to make sense when understood in terms of the (...)
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  • Are Systems Neuroscience Explanations Mechanistic?Carlos Zednik - unknown
    Whereas most branches of neuroscience are thought to provide mechanistic explanations, systems neuroscience is not. Two reasons are traditionally cited in support of this conclusion. First, systems neuroscientists rarely, if ever, rely on the dual strategies of decomposition and localization. Second, they typically emphasize organizational properties over the properties of individual components. In this paper, I argue that neither reason is conclusive: researchers might rely on alternative strategies for mechanism discovery, and focusing on organization is often appropriate and consistent with (...)
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  • Scientific realism and historical evidence: Shortcomings of the current state of debate.Juha Saatsi - 2010 - In Henk W. de Regt (ed.), EPSA Philosophy of Science: Amsterdam 2009. Springer. pp. 329--340.
    This paper discusses three shortcomings of the current state of the debate regarding historical evidence against scientific realism. Attending to these issues will direct the debate away from over-generalising wholesale arguments.
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  • Heuristics, Descriptions, and the Scope of Mechanistic Explanation.Carlos Zednik - 2015 - In P. Braillard & C. Malaterre (eds.), Explanation in Biology. An Enquiry into the Diversity of Explanatory Patterns in the Life Sciences. Dordrecht: Springer. pp. 295-318.
    The philosophical conception of mechanistic explanation is grounded on a limited number of canonical examples. These examples provide an overly narrow view of contemporary scientific practice, because they do not reflect the extent to which the heuristic strategies and descriptive practices that contribute to mechanistic explanation have evolved beyond the well-known methods of decomposition, localization, and pictorial representation. Recent examples from evolutionary robotics and network approaches to biology and neuroscience demonstrate the increasingly important role played by computer simulations and mathematical (...)
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  • Functional Analyses, Mechanistic Explanations, and Explanatory Tradeoffs.Sergio Daniel Barberis - 2013 - Journal of Cognitive Science 14:229-251.
    Recently, Piccinini and Craver have stated three theses concerning the relations between functional analysis and mechanistic explanation in cognitive sciences: No Distinctness: functional analysis and mechanistic explanation are explanations of the same kind; Integration: functional analysis is a kind of mechanistic explanation; and Subordination: functional analyses are unsatisfactory sketches of mechanisms. In this paper, I argue, first, that functional analysis and mechanistic explanations are sub-kinds of explanation by scientific (idealized) models. From that point of view, we must take into account (...)
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  • Naturalism and the Enlightenment ideal : rethinking a central debate in the philosophy of social science.Daniel Steel & S. Kedzie Hall - 2010 - In P. D. Magnus & Jacob Busch (eds.), New Waves in Philosophy of Science. Palgrave-Macmillan.
    The naturalism versus interpretivism debate the in philosophy of social science is traditionally framed as the question of whether social science should attempt to emulate the methods of natural science. I show that this manner of formulating the issue is problematic insofar as it presupposes an implausibly strong unity of method among the natural sciences. I propose instead that what is at stake in this debate is the feasibility and desirability of what I call the Enlightenment ideal of social science. (...)
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  • Large-scale simulations of brain mechanisms: beyond the synthetic method.Edoardo Datteri & Federico Laudisa - unknown
    In recent years, a number of research projects have been proposed whose goal is to build large-scale simulations of brain mechanisms at unprecedented levels of biological accuracy. Here it is argued that the roles these simulations are expected to play in neuroscientific research go beyond the “synthetic method” extensively adopted in Artificial Intelligence and biorobotics. In addition we show that, over and above the common goal of simulating brain mechanisms, these projects pursue various modelling ambitions that can be sharply distinguished (...)
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  • Psycho-neural reduction through functional sub-types.Patrice Soom, Christian Sachse & Michael Esfeld - unknown
    The paper argues that a functional reduction of ordinary psychology to neuropsychology is possible by means of constructing fine-grained functional, mental sub-types that are coextensive with neuropsychological types. We establish this claim by means of considering as examples the cases of the disconnection syndrome and schizophrenia. We point out that the result is a conservative reduction, vindicating the scientific quality of the mental types of ordinary psychology by systematically linking them with neuroscience. That procedure of conservative reduction by means of (...)
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