Objections to the computational theory of cognition, inspired by twentieth century phenomenology, have tended to fixate on the embodiment and embeddedness of intelligence. In this paper I reconstruct a line of argument that focusses primarily on the abstract nature of scientific models, of which computational models of the brain are one sort. I observe that the critique of scientific abstraction was rather commonplace in the philosophy of the 1920s and 30s and that attention to it aids the reading of The (...) Organism ([1934] 1939) by the neurologist Kurt Goldstein. With this background in place, we see that some brief but spirited criticisms of cybernetics by two later thinkers much influenced by Goldstein, Georges Canguilhem (1963) and Maurice Merleau-Ponty (1961), show continuity with the earlier discussions of abstraction in science. (shrink)

The aim of this paper is to present Duhem’s critical view of the dynamical development of mechanics according to two principles of his theory of the development of physics: the continuous and the rational development of physics. These two principles impose a formal conception of physics that aims at demarcating physics from the metaphysical view on the one hand and the pragmatist/conventionalist view on the other hand. Duhem pursues an intermediary conception of physics, a representational system of empirical laws based (...) upon formal principles. This formal conception of physics will adjust to his idea of scientific progress in the form of a sequence of representational systems as structures of increasing comprehensiveness of empirical laws, which leads him to defend a convergent structural realism pointing to an ideal physical theory. (shrink)

The intuition of the naı¨ve realist, miracle arguments notwithstanding, is countered forcefully by a host of considerations, including the possibility of underdetermination, and criticisms of abductive inferences to explanatory hypotheses. Some have suggested that an induction may be performed, from the perspective of present theories, on their predecessors. Past theories are thought to be false, strictly speaking; it is thus likely that present-day theories are also false, and will be taken as such at an appropriate future time.

Structural realism has recently re-entered mainstream discussions in the philosophy of science. The central notion of structure, however, is contested by both advocates and critics. This paper briefly reviews currently prominent structuralist accounts en route to proposing a metaphysics of structure that is capable of supporting the epistemic aspirations of realists, and that is immune to the charge most commonly levelled against structuralism. This account provides an alternative to the existing epistemic and ontic forms of the position, incorporating elements of (...) both. Structures are here identified with relations between first order, causal properties: properties that confer specific dispositions for relations. This form of structuralism constitutes an explicit proposal for what seem implicit structuralist tendencies in sophisticated but more traditional characterizations of realism. An outline of the proposal's response to the anti-realist's pessimistic induction on the history of scientific theories is considered. (shrink)

IntroductionScientific pluralism is generally understood in the backdrop of scientific monism. So is mathematical pluralism. Though there are many culture-dependent mathematical practices, mathematical concepts and theories are generally taken to be culture invariant. We would like to explore in this paper whether mathematical pluralism is admissible or not.Materials and methodsMathematical pluralism may be approached at least from five different perspectives. 1. Foundational: The view would claim that different issues within mathematics need support of different foundations, apparently incompatible with one another. (...) 2. Ontological: The world itself is dappled—the mathematical counterpart of which can be traced to the admission of non-Euclidean spaces and also in simultaneous acceptance of set-theoretic and category theoretic entities in the ontology of mathematics. 3. The third route is epistemological. It follows from the view that the nature of reality is so complex that different aspects of it require alternative modes of representation and explanation sometimes severally, sometimes simultaneously, e.g., classical, constructivist, computer-aided and different finitist mathematics can be used depending on the knowledge situation. 4. The fourth route is semantic. Fuzzy mathematics, we know, gives up bivalence in theory of truth, and ascribes truth to mathematical propositions in degrees. 5. The last one is Programmatic: for some, mathematical pluralism is a stance, a programme. It provides a framework which strikes at the root of cultural hegemony and nourishes a climate of intellectual humility and tolerance. It is not my intention to hold the brief of any of these versions. I just want to present to the readers a more or less complete picture of the scenario, though not an exhaustive one. ConclusionUnlike monism, mathematical pluralism does not rule out any possibility—even the possibility of having a unitary over-arching framework of interpretation remains as an open option. This paper highlights the fact that motivations for upholding pluralism in mathematics have been many and one can be a pluralist just by subscribing to any of the views listed above. (shrink)

This article examines the origins and development of J. J. Thomson's chemical thought, and the reception of his theories by chemists. Thomson's interest in chemical combination and atomic theories of matter dates from his formative schooldays at Owens College, Manchester. These themes constituted a persistent leitmotif in the development of Thomson's style of thought, and provided a powerful stimulus which enabled him to enunciate the concept of electrons as fundamental particles. Thomson's influence on chemists during the years 1903 to 1923 (...) reflects the richness and fertility of his chemical thought. He influenced the absorption of the Victorian physical tradition by American chemists, thus adding a mechanistic, picture-embedded style to theoretical chemistry. Thomson's style of thought resonated with the needs of American chemists, but was ignored in Germany. (shrink)

. The present study applies results and methods of psychobiology to intellectual history. Pascal's syndrome is a depressive neurosis associated with morbid effects of scientific certainty. The syndrome is characterized by self‐mortification and conversion experience that represses distressing certainties. The dynamics of the syndrome are assessed from Blake Pascal's psychosis. The ideation of the syndrome is evaluated by reference to the neurology of altered states of consciousness and the biogenic amine hypothesis of depression and mania. The evaluation yields a description (...) of the relation between psychogenic and biogenic factors in the syndrome's etiology. (shrink)

This article provides an overview of the historical and philosophical context from which originated G. Bachelard's concept of "phenomenotechnique". It analyzes why phenomenotechnique is crucial for science studies. By incorporating the concept of phenomenotechnique into Hacking's and Galison's models of science, I argue that we can avoid the radicalism of both while also preventing the analysis of scientific practices from collapsing into the interpretive frames mandated by social constructivists.

Duhem—Quine underdetermination plays a constructive role in epistemology by pinpointing the impact of non-empirical virtues or cognitive values on theory choice. Underdetermination thus contributes to illuminating the nature of scientific rationality. Scientists prefer and accept one account among empirical equivalent alternatives. The non-empirical virtues operating in science are laid open in such theory choice decisions. The latter act as an epistemological test tube in making explicit commitments to how scientific knowledge should be like.

While endorsing Gopnik's proposal that studies of the emergence and modification of scientific theories and studies of cognitive development in children are mutually illuminating, we offer a different picture of the beginning points of cognitive development from Gopnik's picture of "theories all the way down." Human infants are endowed with several distinct core systems of knowledge which are theory-like in some, but not all, important ways. The existence of these core systems of knowledge has implications for the joint research program (...) between philosophers and psychologists that Gopnik advocates and we endorse. A few lessons already gained from this program of research are sketched. (shrink)

The final chapter of Elgin’s defends the claim that some mistakes mark significant epistemic achievements. Here, I extend Elgin’s analysis of the informativeness of mistakes for epistemic policing. I also examine the type of theory of competence that Elgin’s view requires, and suggest some directions in which this can be taken.

Wolfgang Spohn’s Frege prize lecture, like the work on which it is based, is a tour de force of rich, elegant, coherent argument about how the projected world that we experience is constructed. But we do not live in this projected world nor reason about it. The things Spohn constructs are there from the start—or so my Stanford School pragmatism teaches. This paper explores a deep difference in philosophical approaches—Spohn’s elegant proofs versus the stocky, tangled arguments I advocate—and illustrates how (...) these play out in far more detailed disputes about the nature of causality and causal inference. (shrink)

This chapter contains sections titled: Relationism, Substantivalism and Space‐time Conventionalism about Space‐time Black Holes and Singularities Horizons and Uniformity Conclusion.

It is claimed that the indispensability argument for the existence of mathematical entities (IA) works in a way that allows a proponent of mathematical realism to remain agnostic with regard to how we establish that mathematical entities exist. This is supposed to be possible by virtue of the appeal to confirmational holism that enters into the formulation of IA. Holism about confirmation is supposed to be motivated in analogy with holism about falsification. I present an account of how holism about (...) falsification is supposed to be motivated. I argue that the argument for holism about falsification is in tension with how we think about confirmation and with two principles suggested by Quine for construing a plausible variety of holism. Finally, I show that one of Quine's principles does not allow a proponent of mathematical realism to remain agnostic with regard to how we establish that mathematical entities exist. (shrink)

Quine, taking the molecular constitution of matter as a paradigmatic example, offers an account of the relation between theory confirmation and ontology. Elsewhere, he deploys a similar ontological methodology to argue for the existence of mathematical objects. Penelope Maddy considers the atomic/molecular theory in more historical detail. She argues that the actual ontological practices of science display a positivistic demand for “direct observation,” and that fulfillment of this demand allows us to distinguish molecules and other physical objects from mathematical abstracta. (...) However, the confirmation of the atomic/molecular theory and the development of scientists’ ontological attitudes towards atoms was more complicated and subtle than even Maddy supposes. The present paper argues that the history of the theory in fact supports neither Quine’s and Maddy’s accounts of scientific ontology. There was no general demand from scientists to “see” atoms before they were reckoned to be real; but neither did the indispensable appearance of atoms in the best theory of chemical combination suffice to convince scientists of their reality. (shrink)

In the static field configuration, a spatially-Variable Speed of Light (VSL) scalar gravity model with Lorentz-Poincaré interpretation was shown to reproduce the phenomenology implied by the Schwarzschild metric. In the present development, we effectively cover configurations with source kinematics due to an induced sweep velocity field w. The scalar-vector model now provides a Hamiltonian description for particles and photons in full accordance with the first Post-Newtonian (1-PN) approximation of General Relativity Theory (GRT). This result requires the validity of Poincaré’s Principle (...) of Relativity, i.e. the unobservability of ‘preferred’ frame movement. Poincaré’s principle fixes the amplitude of the sweep velocity field of the moving source, or equivalently the ‘vector potential’ ξ of GRT (e.g.; S. Weinberg, Gravitation and cosmology, [1972]), and provides the correct 1-PN limit of GRT. The implementation of this principle requires acceleration transformations derived from gravitationally modified Lorentz transformations. A comparison with the acceleration transformation in GRT is done. The present scope of the model is limited to weak-field gravitation without retardation and with gravitating test particles. In conclusion the model’s merits in terms of a simpler space, time and gravitation ontology—in terms of a Lorentz-Poincaré-type interpretation—are explained (e.g. for ‘frame dragging’, ‘harmonic coordinate condition’). (shrink)

Implementing Poincaré’s geometric conventionalism a scalar Lorentz-covariant gravity model is obtained based on gravitationally modified Lorentz transformations (or GMLT). The modification essentially consists of an appropriate space-time and momentum-energy scaling (“normalization”) relative to a nondynamical flat background geometry according to an isotropic, nonsingular gravitational affecting function Φ(r). Elimination of the gravitationally unaffected S 0 perspective by local composition of space–time GMLT recovers the local Minkowskian metric and thus preserves the invariance of the locally observed velocity of light. The associated energy-momentum (...) GMLT provides a covariant Hamiltonian description for test particles and photons which, in a static gravitational field configuration, endorses the four ‘basic’ experiments for testing General Relativity Theory: gravitational (i) deflection of light, (ii) precession of perihelia, (iii) delay of radar echo, (iv) shift of spectral lines. The model recovers the Lagrangian of the Lorentz–Poincaré gravity model by Torgny Sjödin and integrates elements of the precursor gravitational theories, with spatially Variable Speed of Light (VSL) by Einstein and Abraham, and gravitationally variable mass by Nordström. (shrink)

Duhem first expounds the holistic thesis, according to which an experimental test always involves several hypotheses, in articles dating from the 1890s. Poincaré's analysis of a recent experiment in optics provides the incentive, but Duhem generalizes this analysis and develops a highly original methodological position. He is led to reject inductivism. I will endeavor to show the crucial role history of science comes to play in the development of Duhem's holism.

Traditionally, empiricism has relied on the specialness of human observation, yet science is rife with sophisticated instrumentation and techniques. The present article advances a conception of empirical evidence applicable to actual scientific practice. I argue that this conception elucidates how the results of scientific research can be repurposed across diverse epistemic contexts: it helps to make sense of how evidence accumulates across theory change, how different evidence can be amalgamated and used jointly, and how the same evidence can be used (...) to constrain competing theories in the service of breaking local underdetermination. (shrink)

Social constructivist approaches to science have often been dismissed as inaccurate accounts of scientific knowledge. In this article, we take the claims of robust social constructivism (SC) seriously and attempt to find a theory which does instantiate the epistemic predicament as described by SC. We argue that Freudian psychoanalysis, in virtue of some of its well-known epistemic complications and conceptual confusions, provides a perfect illustration of what SC claims is actually going on in science. In other words, the features SC (...) mistakenly ascribes to science in general correctly characterize the epistemic status of Freudian psychoanalysis. This sheds some light on the internal disputes in the field of psychoanalysis, on the sociology of psychoanalytic movement, and on the “war” that has been waged over Freud's legacy with his critics. In addition, our analysis offers an indirect and independent argument against SC as an account of bona fide science, by illustrating what science would look like if it were to function as SC claims it does. (shrink)

_ Source: _Page Count 25 The familiar challenges to historiographical knowledge turn on epistemological concerns having to do with the unobservability of historical events, or with the problem of establishing a sufficiently strong inferential connection between evidence and the historiographical claim one wishes to convert from a true belief into knowledge. This paper argues that these challenges miss a deeper problem, viz., the lack of obvious truth-makers for historiographical claims. The metaphysical challenge to historiography is that reality does not appear (...) to co-operate in our cognitive endeavours by providing truth-makers for claims about historical entities and events. Setting out this less familiar, but more fundamental, challenge to the very possibility of historiography is the first aim of this paper. The various ways in which this challenge might be met are then set out, including ontologically inflationary appeals to abstract objects of various kinds, or to “block” theories of time. The paper closes with the articulation of an ontologically parsimonious solution to the metaphysical challenge to historiography. The cost of this approach is a revision to standard theories of truth. The central claim here is that the standard theories of truth have mistaken distinct causes of truth for truth itself. This mistake leads to distorted expectations regarding truth-makers for historiographical claims. The truth-makers of historiographical claims are not so much the historical events themselves but atemporal modal facts about the order of things of which those events were a part. (shrink)

_ Source: _Page Count 25 The familiar challenges to historiographical knowledge turn on epistemological concerns having to do with the unobservability of historical events, or with the problem of establishing a sufficiently strong inferential connection between evidence and the historiographical claim one wishes to convert from a true belief into knowledge. This paper argues that these challenges miss a deeper problem, viz., the lack of obvious truth-makers for historiographical claims. The metaphysical challenge to historiography is that reality does not appear (...) to co-operate in our cognitive endeavours by providing truth-makers for claims about historical entities and events. Setting out this less familiar, but more fundamental, challenge to the very possibility of historiography is the first aim of this paper. The various ways in which this challenge might be met are then set out, including ontologically inflationary appeals to abstract objects of various kinds, or to “block” theories of time. The paper closes with the articulation of an ontologically parsimonious solution to the metaphysical challenge to historiography. The cost of this approach is a revision to standard theories of truth. The central claim here is that the standard theories of truth have mistaken distinct causes of truth for truth itself. This mistake leads to distorted expectations regarding truth-makers for historiographical claims. The truth-makers of historiographical claims are not so much the historical events themselves but atemporal modal facts about the order of things of which those events were a part. (shrink)

Current debate on Structural Realism starts when Worrall suggest this position is capable of accounting for the central intuitions of both Scientific Realism and Antirealism. Since then, it has become a rich field of debate in which complex disputes have emerged. In this paper I maintain that, despite its recent appearance on the philosophical scene, SR constitutes the crowning of an epistemological trend I propose to call ‘structuralist tradition’. I take as its central feature to put the focus on the (...) relations that exist in the natural world, rather than in the nature of the entities that maintain those relations. But despite this common feature, the various positions that have constituted that tradition in general, and the variants of RE in particular, have not offered a precise and uniform notion of structure. (shrink)

The complex societal challenges of the twenty-first Century require scientific researchers and academically educated professionals capable of conducting scientific research in complex problem contexts. Our central claim is that educational approaches inspired by a traditional empiricist epistemology insufficiently foster the required deep conceptual understanding and higher-order thinking skills necessary for epistemic tasks in scientific research. Conversely, we argue that constructivist epistemologies provide better guidance to educational approaches to promote research skills. We also argue that teachers adopting a constructivist learning theory (...) do not necessarily embrace a constructivist epistemology. On the contrary, in educational practice, novel educational approaches that adopt constructivist learning theories often maintain traditional empiricist epistemologies. Philosophers of science can help develop educational designs focused on learning to conduct scientific research, combining constructivist learning theory with constructivist epistemology. We illustrate this by an example from a bachelor’s program in Biomedical Engineering, where we introduce conceptual models and modeling as an alternative to the traditional focus on hypothesis testing in conducting scientific research. This educational approach includes the so-called B&K method for constructing scientific models to scaffold teaching and learning conceptual modeling. (shrink)

In this paper we will propose an empirical analysis of spatial and temporal boundaries. Unlike other proposals, which deal mainly with the commonsense level of the subject, we will ground our explication on well-established scientific practice and language. In this way we show how to reconsider in an innovative way questions such as the distinction between the bona fide boundaries and the fiat boundaries, the thickness and the ownership of the boundaries. At the same time we propose a division between (...) ex mensura boundaries and qui vulgo dicuntur boundaries. What is it, therefore,that divides the atmosphere from the water?[Leonardo da Vinci, Notebooks]. (shrink)

: An examination of two thought experiments in contemporary physics reveals that the same thought experiment can be reanalyzed from the perspective of different and incompatible theories. This fact undermines those accounts of thought experiments that claim their justificatory power comes from their ability to reveal the laws of nature. While thought experiments do play a genuine evaluative role in science, they do so by testing the nonempirical virtues of a theory, such as consistency and explanatory power. I conclude that, (...) while their interpretation presupposes a whole set of background theories and putative laws, thought experiments nonetheless can evolve and be retooled for different theories and ends. (shrink)

Scientists obtain a great deal of the evidence they use by observingnatural and experimentally generated objects and effects. Much of thestandard philosophical literature on this subject comes from20th century logical positivists and empiricists, theirfollowers, and critics who embraced their issues and accepted some oftheir assumptions even as they objected to specific views. Theirdiscussions of observational evidence tend to focus on epistemologicalquestions about its role in theory testing. This entry follows theirlead even though observational evidence also plays important andphilosophically interesting roles (...) in other areas including scientificdiscovery and the application of scientific theories to practicalproblems. (shrink)

Empiricists claim that in accepting a scientific theory one should not commit oneself to claims about things that are not observable in the sense of registering on human perceptual systems (according to Van Fraassen’s constructive empiricism) or experimental equipment (according to what I call liberal empiricism ). They also claim scientific theories should be accepted or rejected on the basis of how well they save the phenomena in the sense delivering unified descriptions of natural regularities among things that meet their (...) conditions for observability. I argue that empiricism is both unfaithful to real world scientific practice, and epistemically imprudent, if not incoherent. To illuminate scientific practice and save regularity phenomena one must commit oneself to claims about causal mechanisms that can be detected from data, but do not register directly on human perceptual systems or experimental equipment. I conclude by suggesting that empiricists should relax their standards for acceptable beliefs. (shrink)

This is the second of a pair of papers, of which the first showed how each of the main late phlogistic theories effectively reached impasses due to internal problems or included features which made them unacceptable even to other phlogistians. This paper deals with theory comparison and theory change. It gives an unprecedentedly detailed comparison between the available theories in 1790–1791, and shows that this was overwhelmingly in favour of the new chemistry. This time period correlates well with many chemists (...) changing to the new theory. There was a plurality of views held by individuals and there was freedom of individual choice concerning theories, yet there was also a widespread and rational change to the new chemistry. (shrink)

In recent years, there have been some attempts to defend the legitimacy of a non-inductive generative logic of discovery whose strategy is to analyze a variety of constraints on the actual generation of explanatory hypotheses. These proposed new theories, however, are only weakly generative (relying on sophisticated processes of elimination) rather than strongly generative (embodying processes of correction).This paper develops a strongly generative theory which holds that we can come to know something new only as a variant of what we (...) already know — and that the novelty of this variant is not thereby eliminated nor beyond our powers of characterization, a double requirement that is vital for resolving the Meno paradox. In this light, the discovery of a new hypothesis is taken as the correction of an antecedent hypothesis in response to the discrepancies between the predictions generated by that antecedent hypothesis and the desired result (e.g. the actual data to be explained). This process comprises two parallel operations: the first, which demonstrates the positive role of the facts in generating new explanations, involves a mapping between multiple hypotheses and sets of predictions generated from those hypotheses, for the purpose of taking the actual data as a determinable variant of neighboring sets of predictions. This mapping permits the facts to indicate how corrective adjustments in the working hypothesis should be made; the second operation, which demonstrates the positive role of explanations in generating new facts, involves a mapping between differently construed versions of the actual data and the conceptualizations derived from those perceptual versions, for the purpose of taking the working hypothesis as a determinable variant of these neighboring conceptualizations. This mapping permits a given hypothesis to generate predictions increasingly closer to the actual facts. (shrink)

Teaching false theories goes against the general pedagogical and philosophical belief that we must only teach and learn what is true. In general, the goal of pedagogy is taken to be epistemic: to gain knowledge and avoid ignorance. In this article, I argue that for realists and antirealists alike, epistemological and pedagogical goals have to come apart. I argue that the falsity of a theory does not automatically make it unfit for being taught. There are several good reasons for teaching (...) false theories in school science. These are false theories can bring about genuine understanding of the world; teaching some false theories from the history of science that line up with children’s ideas can provide students “intellectual empathy” and also aid in better grasp of concepts; teaching false theories from the history of science can sharpen students’ understanding of the nature of science; scientists routinely use false theories and models in their practice and it is good sense for science education to mirror scientific practice; and learning about patently non-scientific and antiscientific ideas will prepare students to face and respond to them. In making arguments for the foregoing five points, I draw upon the work of a variety of philosophers and historians of science, cognitive scientists, science education scholars, and scientists. My goal here is not only to justify theories considered false already being taught, but also to actively endorse the teaching of some theories considered false that are by and large not currently taught. (shrink)

Stump argued for a virtue epistemological reading of Duhem's good sense: according to him Duhem advanced good sense as a source of justified beliefs about theory choice and as a mark of the cognitive character of the physicist. Ivanova argues that Duhem proposed good sense as a post hoc explanation of theory choice rather than as a justification of it. I contend that Ivanova’s reading of Duhem is inaccurate and that good sense can indeed be accommodated within virtue epistemology. However (...) Stump’s account is incomplete: I propose that within virtue epistemology, agent reliabilism best accommodates Duhemian good sense. (shrink)

This paper construes various positions in the philosophy of science and the philosophy of law as responses to the problem of underdetermination in science and in law. We begin by drawing a close analogy between the successive approaches to this problem in the two fields. In particular, we stress the analogy between conventionalism as a philosophy of science and legal realism as a philosophy of law, and between Putnam's and Dworkin's critiques of these positions. We then challenge the Putnam-Dworkin strategy, (...) arguing that their attempts to combat underdetermination are unsuccessful. We are thus led to scepticism regarding the outlook underlying the celebrated maxim, “ruled by law, not by men”. (shrink)

This paper examines the epistemological significance of the present situation of underdetermination in quantum mechanics. After analyzing this underdetermination at three levels---formal, ontological, and methodological---the paper considers implications for a number of variants of the thesis of scientific realism in fundamental physics and reassesses Lakatos‘ characterization of progress in physical theory in light of the present situation. Next, this paper considers the implications of underdetermination for Weinberg’s ‘‘dream of a final theory.’’ Finally, the paper concludes by suggesting how one might (...) still think of realism and progress in fundamental physics despite the possibility of persistent underdetermination in quantum mechanics. (shrink)

The question to be addressed is, In what sense and to what extent do quantum statistics for, and the standard formal quantum-mechanical description of, systems of many identical particles entail that identical quantum particles are indistinguishable? This paper argues that whether or not we consider identical quantum particles as indistinguishable is a matter of theory choice underdetermined by logic and experiment.

If cosmology is to obtain knowledge about the whole universe, it faces an underdetermination problem: Alternative space-time models are compatible with our evidence. The problem can be avoided though, if there are good reasons to adopt the Cosmological Principle (CP), because, assuming the principle, one can confine oneself to the small class of homogeneous and isotropic space-time models. The aim of this paper is to ask whether there are good reasons to adopt the Cosmological Principle in order to avoid underdetermination (...) in cosmology. Various strategies to justify the CP are examined. For instance, arguments to the effect that the truth of the CP follows generically from a large set of initial conditions; an inference to the best explanation; and an inductive strategy are assessed. I conclude that a convincing justification of the CP has not yet been established, but this claim is contingent on a number of results that may have to be revised in the future. (shrink)

Computer simulations and experiments share many important features. One way of explaining the similarities is to say that computer simulations just are experiments. This claim is quite popular in the literature. The aim of this paper is to argue against the claim and to develop an alternative explanation of why computer simulations resemble experiments. To this purpose, experiment is characterized in terms of an intervention on a system and of the observation of the reaction. Thus, if computer simulations are experiments, (...) either the computer hardware or the target system must be intervened on and observed. I argue against the first option using the non-observation argument, among others. The second option is excluded by e.g. the over-control argument, which stresses epistemological differences between experiments and simulations. To account for the similarities between experiments and computer simulations, I propose to say that computer simulations can model possible experiments and do in fact often do so. (shrink)

The notion of a severe test has played an important methodological role in the history of science. But it has not until recently been analyzed in any detail. We develop a generally Bayesian analysis of the notion, compare it with Deborah Mayo’s error-statistical approach by way of sample diagnostic tests in the medical sciences, and consider various objections to both. At the core of our analysis is a distinction between evidence and confirmation or belief. These notions must be kept separate (...) if mistakes are to be avoided; combined in the right way, they provide an adequate understanding of severity. Those who think that the weight of the evidence always enables you to choose between hypotheses “ignore one of the factors (the prior probability) altogether, and treat the other (the likelihood) as though it ...meant something other than it actually does. This is the same mistake as is made by someone who has scruples about measuring the arms of a balance (having only a tape measure at his disposal ...), but is willing to assert that the heavier load will always tilt the balance (thereby implicitly assuming, although without admitting it, that the arms are of equal length!). (Bruno de Finetti, Theory of Probability)2. (shrink)

The article analyses in detail the Meselson–Stahl experiment, identifying two novel difficulties for the crucial experiment account, namely, the fragility of the experimental results and the fact that the hypotheses under scrutiny were not mutually exclusive. The crucial experiment account is rejected in favour of an experimental-mechanistic account of the historical significance of the experiment, emphasizing that the experiment generated data about the biochemistry of DNA replication that is independent of the testing of the semi-conservative, conservative, and dispersive hypotheses. _1_ (...) Introduction _2_ The Meselson–Stahl Experiment _3_ Some Difficulties for the Crucial Experiment Account _3.1_ Additional experiments were required _3.2_ Simplicity considerations are unconvincing _3.3_ The fragility of the experimental results _3.4_ The problematic interpretation of falsifyng results _3.5_ Not all possible hypotheses considered or tested _3.6_ The tested hypotheses were not mutually exclusive _4_ The Historical and Scientific Significance of the Meselson–Stahl Experiment _4.1_ The challenge for the crucial experiment account _4.2_ A mechanistic perspective on the experiment _4.3_ The experimental design and its independence from theoretical speculations _4.4_ The advantages of a ‘bottom-up’ mechanistic account _5_ Conclusion. (shrink)