The meaning of scientific propositions is not always expressible in terms of observable phenomena. Such propositions involve generalizations, and also terms that are theoretical constructs. I study here how to assess the meaning of scientific propositions, that is, the specific import of theoretical terms. Empiricists have expressed a concern that scientific propositions, and theoretical terms, should always be, to some degree, related to observable consequences. We can see that the former empiricist criterion of meaning only implies for theoretical terms not (...) to be definable in terms of observable, but that their use put a constraint on the observable consequences of a theory. To that effect, Ramsey's method of formal elimination of theoretical terms can be an interesting tool. It has faced important logical objections, which have mostly been addressed with respect to the problem of the ontological commitment of the second-order quantification they imply. I show here that these criticisms can be overcome, and that there can be a successful Ramsey elimination of theoretical terms with first order sentences, making Ramsey's method a relevant tool to assess the empirical meaning of scientific propositions. (shrink)

What is the status of a cat in a virtual reality environment? Is it a real object? Or part of a fiction? Virtual realism, as defended by D. J. Chalmers, takes it to be a virtual object that really exists, that has properties and is involved in real events. His preferred specification of virtual realism identifies the cat with a digital object. The project of this paper is to use a comparison between virtual reality environments and scientific computer simulations to (...) critically engage with Chalmers’s position. I first argue that, if it is sound, his virtual realism should also be applied to objects that figure in scientific computer simulations, e.g. to simulated galaxies. This leads to a slippery slope because it implies an unreasonable proliferation of digital objects. A philosophical analysis of scientific computer simulations suggests an alternative picture: The cat and the galaxies are parts of fictional models for which the computer provides model descriptions. This result motivates a deeper analysis of the way in which Chalmers builds up his realism. I argue that he buys realism too cheap. For instance, he does not really specify what virtual objects are supposed to be. As a result, rhetoric aside, his virtual realism isn’t far from a sort of fictionalism. (shrink)

Computer simulations and experiments share many important features. One way of explaining the similarities is to say that computer simulations just are experiments. This claim is quite popular in the literature. The aim of this paper is to argue against the claim and to develop an alternative explanation of why computer simulations resemble experiments. To this purpose, experiment is characterized in terms of an intervention on a system and of the observation of the reaction. Thus, if computer simulations are experiments, (...) either the computer hardware or the target system must be intervened on and observed. I argue against the first option using the non-observation argument, among others. The second option is excluded by e.g. the over-control argument, which stresses epistemological differences between experiments and simulations. To account for the similarities between experiments and computer simulations, I propose to say that computer simulations can model possible experiments and do in fact often do so. (shrink)

The issue of the conservatism of scientific research questions the nature and the role of the internal and external forces controlling the emergence of new research questions or problems, the exploration of risky directions of research, or the use of risky research methods. This issue has recently gained a new framing in connection with the growing importance of the peer-review process and of the social and economic pressures weighing on the funding of scientific research. Current literature then interrogates the external (...) and internal features that promote what are described as conservative tendencies in scientific research. In this paper, I propose to contribute to this debate by clarifying what might be internal sources of conservatism in science; that is, that are inherent to the research process itself. I distinguish two possible understandings of the sources and manifestations of this internal conservatism. I first present a representational description of the nature and origin of conservatism in science, which brings to the fore the difficulties researchers find in setting aside their conceptual framework. I then offer for consideration a larger perspective on conservatism by arguing for the existence of a practical conservatism generated by all the dimensions of scientific activities. In this framework, conservatism in science can be explained by the tendency of all practices to close in on their own local objectives. I illustrate this view by reference to an historical episode: the discovery of the chemical nature of genes by Avery. (shrink)

The question of the division of cognitive labor has given rise to various models characterizing the way scientists should distribute their efforts. These models often consider the scientific community as a self-governed sphere constituted by rational agents making choices on the basis of fixed rules. Such models have recently been criticized for not taking into account the real mechanisms of science funding. Hence, the question of the utility of the DCL models in guiding science policy remains an open one. In (...) this paper, we show that two unconsidered dimensions would have to be taken into account. First, DCL studies miss the existence of distinct levels of epistemic objectives organizing the research process. Indeed, the scientific field is structured as a system of hierarchical, interconnected practices which are defined both by their inherent purposes and by various superposed external functions. Second, I criticize the absence of ontological considerations, since the epistemological significance of pluralism is highly dependent on the nature of the object under study. Because of these missing dimensions, current DCL models might have a limited usefulness to identify good practices of research governance. (shrink)

Research devoted to characterizing phenomena is underappreciated in philosophical accounts of scientific inquiry. This paper develops a diachronic analysis of research over 100 years that led to the recognition of two related electrophysiological phenomena, the membrane potential and the action potential. A diachronic perspective allows for reconciliation of two threads in philosophical discussions of phenomena—Hacking’s treatment of phenomena as manifest in laboratory settings and Bogen and Woodward’s construal of phenomena as regularities in the world. The diachronic analysis also reveals the (...) epistemic tasks that contribute to establishing phenomena, including the development of appropriate investigative techniques and concepts for characterizing them. (shrink)

According to a common belief concerning the Mach-Boltzmann debate on atoms, the new experiments performed in microphysics at the turn of the 19th and 20th centuries confirmed Boltzmann's atomic hypothesis and disproved Mach's anti-atomic view. This paper intends to show that this belief is partially unjustified. Mach's view on atoms consists in fact of different kinds of arguments. While the new experiments in microphysics refute indeed his scientific arguments against the atomic hypothesis, his epistemological arguments are unaffected. In this regard, (...) Mach's epistemological approach remains relevant for today's discussion on the status of the notion of atom. (shrink)

Putnam's ``model-theoretic'' argument against metaphysical realism presupposes that an ideal scientific theory is expressible in a first order language. The central aim of this paper is to show that Putnam's ``first orderization'' of science, although unchallenged by numerous critics, makes his argument unsound even for adequate theories, never mind an ideal one. To this end, I will argue that quantitative theories, which dominate the natural sciences, can be adequately interpreted and evaluated only with the help of so-called theories of measurement (...) whose epistemological and methodological purpose is to justify systematic assignments of quantitative values to objects in the world. And, in order to fulfill this purpose, theories of measurement must have an essentially higher order logical structure. As a result, Putnam's argument fails because much of science turns out to rest on essentially higher order theoretical assumptions about the world. (shrink)

When Ron Giere introduced perspectivism into philosophy of science, he provided a perspectivist analysis of both scientific instruments and scientific theorizing. Today, there is a burgeoning literature that extends Giere’s analysis of theorizing, with many philosophers examining the perspectivist approach to aspects of theorizing such as models, laws, explanations, and so on. However, relatively little attention has been paid to Giere’s analysis of instruments. In this article, I hope to fill this gap. I argue that the perspectivist analysis of instruments (...) should be rejected. First, I give a general account of the kind of instrumentation relevant to instrumental perspectivism, drawing on Cartwright’s notion of nomological machines, which forms the basis of my criticism of Giere’s argument for instrumental perspectivism. Next, I present the case against instrumental perspectivism. I argue that instrumental perspectivism is dependent on theoretical perspectivism in a way that robs it of philosophical significance, and that it introduces new puzzles while adding little to our understanding of instruments. (shrink)

Social Epistemology, as formulated by Steve Fuller, is based on the suggestion that rational knowledge policy must be held accountable to ‘brute facts’ about the nature of our human cognitive pursuits, whatever these may be. One difficulty for Fuller concerns the conception of the social which underwrites social epistemology. I argue that social epistemology conflates the social with human psychological properties that are available for public scrutiny and, accordingly, that social epistemology is best viewed as a brand of psychologism. Though (...) Fuller's proposal signifies an important step in the ongoing attempt by scholars to eradicate the last traces of Descartes' epistemological device of a disembodiedres cogitans, I conclude that his conception of the social is too weak to serve as the basis for a socially-embedded discipline in anything but name only. (shrink)

Multidisciplinary models aggregating ‘lower-level’ biological and ‘higher-level’ psychological and social determinants of a phenomenon raise a puzzle. How is the interaction between the physical, the psychological and the social conceptualized and explained? Using biopsychosocial models of pain as an illustration, I argue that these models are in fact level-neutral compilations of empirical findings about correlated and causally relevant factors, and as such they neither assume, nor entail a conceptual or ontological stratification into levels of description, explanation or reality. If inter-level (...) causation is deemed problematic or if debates about the superiority of a particular level of description or explanation arise, these issues are fueled by considerations other than empirical findings. (shrink)

The article analyses in detail the Meselson–Stahl experiment, identifying two novel difficulties for the crucial experiment account, namely, the fragility of the experimental results and the fact that the hypotheses under scrutiny were not mutually exclusive. The crucial experiment account is rejected in favour of an experimental-mechanistic account of the historical significance of the experiment, emphasizing that the experiment generated data about the biochemistry of DNA replication that is independent of the testing of the semi-conservative, conservative, and dispersive hypotheses. _1_ (...) Introduction _2_ The Meselson–Stahl Experiment _3_ Some Difficulties for the Crucial Experiment Account _3.1_ Additional experiments were required _3.2_ Simplicity considerations are unconvincing _3.3_ The fragility of the experimental results _3.4_ The problematic interpretation of falsifyng results _3.5_ Not all possible hypotheses considered or tested _3.6_ The tested hypotheses were not mutually exclusive _4_ The Historical and Scientific Significance of the Meselson–Stahl Experiment _4.1_ The challenge for the crucial experiment account _4.2_ A mechanistic perspective on the experiment _4.3_ The experimental design and its independence from theoretical speculations _4.4_ The advantages of a ‘bottom-up’ mechanistic account _5_ Conclusion. (shrink)

I argue that informational models of consciousness, including those proposed by the Integrated Information Theory, don’t presuppose or entail any particular view about the physical or metaphysical nature of consciousness. Such models only tell us how certain properties of consciousness can be mathematically described, thus providing a quantitative characterization of the phenomenon of consciousness that may contribute to the development of new methods of assessment and guide the explanatory project by supplying additional constraints on theoretical proposals. While informational models are (...) in principle compatible with multiple physical interpretations, a preliminary argument in favour of the continuity between informational approaches and the mechanistic project in neuroscience can be made based on historical precedents. (shrink)

Causal mediation mechanisms are well supported by available experimental evidence and provide a practicable way to reductive physicalism. According to the causal mediation account of mechanistic explanation, descriptions as diverse as ‘black-box’ phenomena, mechanistic sketches and schemas mixing physically interpreted and operationalized biological, psychological and social variables, and detailed descriptions of mechanisms refer to the same causal structure circumscribed within the spatiotemporal boundaries of a replicable experimental setup. The coreference of coarser- and finer-grained descriptions of causal structures opens new possibilities (...) for testing the reductive physicalism conjecture. I discuss experimental designs supporting the causal mediation account and show how recent studies demonstrating the biological mediation of mind-mind causal processes can provide evidence for reductive physicalism. (shrink)

This essay raises the question of material hermeneutics in Heelan’s philosophy of techno-science. For Heelan, a continental philosophy of technoscience, referring to Husserl and Heidegger and especially to Merleau-Ponty, features hermeneutic contexts of mathematics and measurement as well as laboratory observation, including what the later Heelan spoke of as “portable laboratories,” for the sake of objectivity and “meaning making.” For Paul Feyerabend, this material practice corresponded to the use of both techniques of observation and instrumentation, and not less “propaganda” in (...) the case of Galileo which practice for Heelan included the ontological status of measures and numbers as well as apprenticeship in what Heelan called “contingent local practical cultural milieus.” The essay includes a discussion of Heidegger on mathematics and Bruno Latour on pasteurization. (shrink)

This article argues that the limited influence of Ludwik Fleck's ideas on philosophy of science is due not only to their indirect dissemination by way of Thomas Kuhn, but also to an incommensurability between the standard conceptual framework of history and philosophy of science and Fleck's own more integratedly historico-social and praxis-oriented approach to understanding the evolution of scientific discovery. What Kuhn named "paradigm" offers a periphrastic rendering or oblique translation of Fleck's Denkstil/Denkkollektiv , a derivation that may also account (...) for the lability of the term "paradigm". This was due not to Kuhn's unwillingness to credit Fleck but rather to the cold war political circumstances surrounding the writing of The Structure of Scientific Revolutions . Following a discussion of Fleck's anatomical allusions, I include a brief discussion of Aristotle (on menstruation and darkened mirrors) and conclude with a reference to the productivity of error in Mach and Nietzsche. (shrink)

A normative constraint on theories about objects which we take to be real is explored: such theories are required to track the properties of the objects which they are theories of. Epistemic views in which observation (and generalizations of it) play a central role, and holist views which see epistemic virtues as applicable only to whole theories, are contrasted in the light of this constraint. It's argued that global-style epistemic virtues can't meet the constraint, although (certain) epistemic views within which (...) observation (and, more generally, thick epistemic access) are centralized do meet it. (shrink)

All sides in the recent debates over the Quine‐Putnam Indispensability thesis presuppose Quine's criterion for determining what a discourse is ontologically committed to. I subject the criterion to scrutiny, especially in regard to the available competitor‐criteria, asking what means of evaluation there are for comparing alternative criteria against each other. Finding none, the paper concludes that ontological questions, in a certain sense, are philosophically indeterminate.

The ramifications are explored of taking physical theories to commit their advocates only to ‘physically real’ entities, where ‘physically real’ means ‘causally efficacious’ (e.g., actual particles moving through space, such as dust motes), the ‘physically significant’ (e.g., centers of mass), and the merely mathematical—despite the fact that, in ordinary physical theory, all three sorts of posits are quantified over. It's argued that when such theories are regimented, existential quantification, even when interpreted ‘objectually’ (that is, in terms of satisfaction via variables, (...) rather than by substitution-instances) need not imply any ontological commitments. (shrink)

This essay argues that the really useful character of reflexivity is that it enables a radical critique of representation and its conventional material and rhetorical practices. It is uniquely able to produce paradox and thus disrupt discourses by undermining authorial privilege. Because Fuller's social epistemology is insensitive to its own reflexive implications, and limits itself to normative questions about knowledge policy, it is too limited — and limiting — to provide a context that can nurture reflexivity.

Scientific realism and anti-realism are most frequently discussed as global theses: theses that apply equally well across the board to all the various sciences. Against this status quo I defend the localist alternative, a methodological stance on scientific realism that approaches debates on realism at the level of individual sciences, rather than at science itself. After identifying the localist view, I provide a number of arguments in its defense, drawing on the diversity and disunity found in the sciences, as well (...) as problems with other approaches (such as basing realism debates on the aim of science). I also show how the view is already at work, explicitly or implicitly, in the work of several philosophers of science. After meeting the objections that localism collapses either into globalism or hyperlocalism, I conclude by sketching what sorts of impacts localism can have in the philosophy of science. (shrink)

The historical variation of scientific knowledge has lent itself to the development of historical epistemology, which attempts to historicize the origin and establishment of knowledge claims. The questions I address in this paper revolve around the historicity of the objects of those claims: How and why do new scientific objects appear? What exactly comes into being in such cases? Do scientific objects evolve over time and in what ways? I put forward and defend two theses: First, the ontology of science (...) is so rich and variegated that there are no universally valid answers to these questions. Second, we need a pluralist account of scientific objects, a pluralist metaphysics that can do justice to their rich diversity and their various modes of being and becoming. I then focus on hidden objects, which are supposed to be part of the permanent furniture of the universe, and I discuss their birth and historicity: They emerge when various phenomena coalesce as manifestations of a single hidden cause and their representations change over time. Finally, I examine the conditions under which an evolving representation may still refer to the same object and I illustrate my argument drawing upon the early history of electrons. (shrink)

This paper takes part in the methodological debate concerning the nature and the justification of hypotheses about computational systems in software engineering by providing an epistemological analysis of Software Testing, the practice of observing the programs’ executions to examine whether they fulfil software requirements. Property specifications articulating such requirements are shown to involve falsifiable hypotheses about software systems that are evaluated by means of tests which are likely to falsify those hypotheses. Software Reliability metrics, used to measure the growth of (...) probability that given failures will occur at specified times as new executions are observed, is shown to involve a Bayesian confirmation of falsifiable hypotheses on programs. Coverage criteria, used to select those input values with which the system under test is to be launched, are understood as theory-laden principles guiding software tests, here compared to scientific experiments. Redundant computations, fault seeding models and formal methods used in software engineering to evaluate test results are taken to be instantiations of some epistemological strategies used in scientific experiments to distinguish between valid and non-valid experimental outcomes. The final part of the paper explores the problem, advanced in the context of the philosophy of technology, of defining the epistemological status of software engineering by conceiving it as a scientifically attested technology. (shrink)

b>. Recent findings in cognitive science suggest that the epistemic subject is more complex and epistemically porous than is generally pictured. Human knowers are open to the world via multiple channels, each operating for particular purposes and according to its own logic. These findings need to be understood and addressed by the philosophical community. The current essay argues that one consequence of the new findings is to invalidate certain arguments for epistemic anti-realism.

The Galilean explanatory style is characterized by the search for the underlying structure of phenomena, the positing of "deep" explanatory principles, and a view of the relation between theory and data, on which the search for "crucial data" is of primary importance. In this paper, I trace the dynamics of adopting the Galilean style, focusing on the science of episodic memory. I argue that memory systems, such as episodic and semantic memory, were posited as underlying competences producing the observable phenomena (...) of memory. Considered in idealized isolation from other systems, episodic memory was taken to underlay the ability of individuals to remember events from their personal past. Yet, in reality, memory systems regularly interact, standing in many-to-many relations to actual memory tasks and experiences. Upon this backdrop, I explore a puzzle about the increasing prominence of the notion of autonoetic consciousness in Tulving's theory of episodic memory. I argue that, contrary to widespread belief, the prominence is not best explained by the purported essential link between autonoetic consciousness and episodic memory. Rather, it is explained by the fact that autonoetic consciousness, hypothesized to uniquely accompany episodic retrieval, was considered a source of crucial data, predictable only from theories positing a functionally distinct episodic memory system. However, with the emergence of a new generation of theories, positing wider memory systems for remembering and imagination, the question of the relation between episodic memory and autonoetic consciousness has been reopened. This creates a pressing need for de-idealization, triggering a new search for crucial data. (shrink)

Putnam originally developed his causal theory of meaning in order to support scientific realism and reject the notion of incommensurability. Later he gave up this position and adopted instead what he called ‘internal realism’, but apparently without changing his mind on topics related to his former philosophy of language. The question must arise whether internal realism, which actually is a species of antirealism, is compatible with the causal theory of meaning. In giving an answer I begin with an analysis of (...) the content and metaphysical background of scientific realism. I show that it presupposes metaphysical realism and that Putnam's philosophical conversion is due to his becoming aware of the latter's incoherence. After giving a brief sketch of internal realism I conclude by arguing that within this new theoretical framework the causal theory of meaning loses its force as a weapon against incommensurability. (shrink)

The ideas of interdisciplinarity and transdisciplinarity have been widely applied to the relationship between sciences. This article is an attempt to discuss the reasons why scientific interdisciplinarity and transdisciplinarity pose specific problems. First of all, certain questions about terminology are taken into account in order to clarify the meaning of the word ?discipline? and its cognates. Secondly, we argue that the specificity of sciences does not lie in becoming disciplines. Then, we focus on the relationship between sciences, and between sciences (...) and technologies: we argue that multidisciplinarity and interdisciplinarity are a common practice among strict sciences and technologies. Finally, we discuss the different meanings of transdisciplinarity when it is applied to sciences. (shrink)

Paul Boyer shared a Nobel Prize in 1997 for his work on the mechanism of ATP synthase. His earlier work, though (which contributed indirectly to his triumph), included major errors, both experimental and theoretical. Two benchmark cases offer insight into how scientists err and how they deal with error. Boyer's work also parallels and illustrates the emergence of bioenergetics in the second half of the twentieth century, rivaling achievements in evolution and molecular biology.

Indigenous cultures of North America confronted a problem of knowledge different from that of canonical European philosophy. The European problem is to identify and overcome obstacles to the perfection of knowledge as science, while the Indigenous problem is to conserve a legacy of practice fused with a territory. Complicating the difference is that one of these traditions violently colonized the other, and with colonization the Indigenous problem changes. The old problem of inter-generational stability cannot be separated from the post-colonial problem (...) of sovereignty in the land where the knowledge makes sense. I differentiate the question of the value of knowledge (Part One), and its content (Part Two). The qualities these epistemologies favor define what I call ceremonial knowledge, that is, knowledge that sustains a ceremonial community. The question of content considers the interdisciplinary research of Indigenous and Traditional Ecological Knowledge, as well as the issue of epistemic decolonization. (shrink)

Indigenous cultures of North America confronted a problem of knowledge different from that of canonical European philosophy. The European problem is to identify and overcome obstacles to the perfection of knowledge as science, while the Indigenous problem is to conserve a legacy of practice fused with a territory. Complicating the difference is that one of these traditions violently colonized the other, and with colonization the Indigenous problem changes. The old problem of inter-generational stability cannot be separated from the post-colonial problem (...) of sovereignty in the land where the knowledge makes sense. I differentiate the question of the value of knowledge (Part 1), and its content (Part 2). The qualities these epistemologies favor define what I callceremonial knowledge, that is, knowledge that sustains a ceremonial community. The question of content considers the interdisciplinary research of Indigenous and Traditional Ecological Knowledge, as well as the issue of epistemic decolonization. (shrink)

: Errors in science range along a spectrum from those relatively local to the phenomenon (usually easily remedied in the laboratory) to those more conceptually derived (involving theory or cultural factors, sometimes quite long-term). One may classify error types broadly as material, observational, conceptual or discoursive. This framework bridges philosophical and sociological perspectives, offering a basis for interfield discourse. A repertoire of error types also supports error analytics, a program for deepening reliability through strategies for regulating and probing error.

It has been argued that the fundamental laws of physics are deceitful in that they give the impression of greater unity and coherence in our theories than is actually found to be the case. Causal stories and phenomenological relationships are claimed to provide a more acceptable account of the world, and only theoretical entities — not laws — are considered as perhaps corresponding to real features of the world.This paper examines these claims in the light of the author's own field (...) of research: high energy physics. Some of the distinctions upon which the above conclusions are based are found not to be tenable in practice. Examples from experimental particle physics are presented which suggest an important role of the underlying theoretical structure which cannot be overlooked. It is argued that the fundamental theories must, in fact, be treated as being as worthy or unworthy of ontological commitment as the entities they postulate or the phenomenological relationships they inspire. Whilst it is conceded that aspects of the current theoretical formalism belie literal interpretation, it is maintained that revision in these particular areas need not affect the symmetry principles, particle spectra, or coupling strengths that largely determine the empirical content of the theory. (shrink)

In the 1950s–60s biochemists searched intensively for a series of high-energy molecules in the cell. Although we now believe that these molecules do not exist, biochemists claimed to have isolated or identified them on at least sixteen occasions. The episode parallels the familiar eighteenth-century case of phlogiston, in illustrating how error is not simply the loss of facts but, instead, must be actively constructed. In addition, the debates surrounding each case demonstrate how revolutionary-scale disagreement is sometimes resolved by differentiating or (...) partitioning empirical domains, rather than by replacement of one theory by another. (shrink)

The empirical underdetermination of theories is a philosophical problem which until the last century has not seriously troubled actual science. The reason is that confirmation does not depend only on empirical consequences, and theoretical virtues allow to choose among empirically equivalent theories. Moreover, I argue that the theories selected in this way are not just pragmatically or aesthetically better, but more probably true. At present in quantum mechanics not even theoretical virtues allow to choose among many competing theories and interpretations, (...) but this is because none of them possess those virtues to a sufficient degree. However, first, we can hope for some future advancement. Second, even if no further progress came forth, all the most credited competitors agree on a substantial core of theoretical assumptions. Therefore underdetermination does not show that we cannot be realist on unobservable entities in general, but at most that in particular fields our inquiry may encounter some de facto limits. (shrink)

On the basis of Levin’s claim that truth is not a scientific explanatory factor, Michel Ghins argues that the “no miracle” argument (NMA) is not scientific, therefore scientific realism is not a scientific hypothesis, and naturalism is wrong. I argue that there are genuine senses of ‘scientific’ and ‘explanation’ in which truth can yield scientific explanations. Hence, the NMA can be considered scientific in the sense that it hinges on a scientific explanation, it follows a typically scientific inferential pattern (IBE), (...) and it is based on an empirical fact (the success of science). Scientific realism, in turn, is scientific in the sense that it is supported both by a meta-level scientific argument (the NMA), and by first level scientific arguments through semantic ascent and generalization. However, both the NMA and scientific realism are not purely scientific, since they go beyond properly scientific concerns, and require additional philosophical reasoning. In turn, naturalism is correct in the sense that philosophy is continuous with science, partly based on it, and potentially equally well warranted. Beside denying the scientific nature of the NMA, Ghins raises some objections to its cogency , to which I reply in the final section. (shrink)

Epistemologists have debated at length whether scientific discovery is a rational and logical process. If it is, according to the Artificial Intelligence hypothesis, it should be possible to write computer programs able to discover laws or theories; and if such programs were written, this would definitely prove the existence of a logic of discovery. Attempts in this direction, however, have been unsuccessful: the programs written by Simon's group, indeed, infer famous laws of physics and chemistry; but having found no new (...) law, they cannot properly be considered discovery machines. The programs written in the Turing tradition, instead, produced new and useful empirical generalization, but no theoretical discovery, thus failing to prove the logical character of the most significant kind of discoveries. A new cognitivist and connectionist approach by Holland, Holyoak, Nisbett and Thagard, looks more promising. Reflection on their proposals helps to understand the complex character of discovery processes, the abandonment of belief in the logic of discovery by logical positivists, and the necessity of a realist interpretation of scientific research. (shrink)

In his recent book on Darwinism, Daniel Dennett has offered up a species of a priori selectionism that he calls algorithmic. He used this view to challenge a number of positions advocated by Stephen J. Gould. I examine his algorithmic conception, review his unqualified enthusiasm for the a priori selectionist position, challenge Dennett's main metaphors (cranes vs. skyhooks and a design space), examine ways in which his position has lead him to misunderstand or misrepresent Gould (spandrels, exaptation, punctuated equilibrium, contingency (...) and disparity), and discuss recent results in developmental biology that suggest that an a priori position does not fill the demands of an evolutionary biology. I conclude by insisting that evolutionary biology is many leveled, complicated, and is carried on an ever shifting and expanding empirical base that when disregarded results in caricature. (shrink)

O presente artigo se propõe a confrontar uma leitura antirrealista da obra do fenomenólogo Edmund Husserl e a sugerir que ela pode ser interpretada mais adequadamente como marco do realismo científico. Para tanto, primeiramente, será exposto um dos mais recentes e elaborados projetos nos quais Husserl se relaciona ao Empirismo Construtivo de Van Fraassen. Posteriormente, serão assinaladas as dificuldades encontradas para interpretar algumas teses de Husserl desde o marco antirrealista, enfocando, principalmente, a discussão sobre os inobserváveis, mostrando como a sua (...) existência não é uma tese indiferente à fenomenologia husserliana. Por fim, será indicado como Husserl poderia estar mais próximo do marco realista. In this paper I confront an anti-realistic approach to Edmund Husserl's Phenomenological work and I suggest that this work could most suitably constitute into the Scientific Realistic framework. In order to this, I will first show one of most recent and elaborate claims which relates Husserl with Van Fraassen's Constructive Empiricism. Later, I will point out some existing difficulties to interpret the Husserlian thesis using the anti-realist framework. I will specially focus on the discussion about unobservable entities, arguing how the existence of the unobservable is not an alien thesis to the Phenomenology of Husserl. Finally, I will point out how Husserl is closer to the Realistic framework. (shrink)

It is a widely shared view among philosophers of science that the theory-dependence (or theory-ladenness) of observations is worrying, because it can bias empirical tests in favour of the tested theories. These doubts are taken to be dispelled if an observation is influenced by a theory independent of the tested theory and thus circularity is avoided, while (partially) circular tests are taken to require special attention. Contrary to this consensus, it is argued that the epistemic value of theory-dependent tests has (...) nothing to do with the circularity or non-circularity of the test, but is instead based on the minimal empiricality and reliability of observations. Since theory-dependence does not in general prevent observations fulfilling these requirements, it should not be regarded as a phenomenon that is basically detrimental, but as neutral with respect to successful scientific knowledge gathering. (shrink)

Rational drug design is a method for developing new pharmaceuticals that typically involves the elucidation of fundamental physiological mechanisms. It thus combines the quest for a scientific understanding of natural phenomena with the design of useful technology and hence integrates epistemic and practical aims of research and development. Case studies of the rational design of the cardiovascular drugs propranolol, captopril and losartan provide insights into characteristics and conditions of this integration. Rational drug design became possible in the 1950s when theoretical (...) knowledge of drug-target interaction and experimental drug testing could interlock in cycles of mutual advancement. The integration does not, however, diminish the importance of basic research for pharmaceutical development. Rather, it can be shown that still in the 1990s, linear processes of innovation and the close combination of practical and epistemic work were interdependent. (shrink)