In this paper, we offer a descriptive theory of analogical reasoning in mathematics, stating general conditions under which an analogy may provide genuine inductive support to a mathematical conjecture (over and above fulfilling the merely heuristic role of ‘suggesting’ a conjecture in the psychological sense). The proposed conditions generalize the criteria of Hesse in her influential work on analogical reasoning in the empirical sciences. By reference to several case studies, we argue that the account proposed in this paper does a (...) better job in vindicating the use of analogical inference in mathematics than the prominent alternative defended by Bartha. (shrink)

This paper proposes a framework for representing in Bayesian terms the idea that analogical arguments of various degrees of strength may provide inductive support to yet untested scientific hypotheses. On this account, contextual information plays a crucial role in determining whether, and to what extent, a given similarity or dissimilarity between source and target may confirm an empirical hypothesis over a rival one. In addition to showing confirmation by analogy compatible with the adoption of a Bayesian standpoint, the proposal outlined (...) in this paper reveals a close agreement between the fulfillment of Hesse’s (Models and analogies in science, University of Notre Dame Press, 1963) criteria for analogical arguments capable of inductive support and the attribution of confirmatory power by the lights of Bayesian confirmation theory. In this sense, the Bayesian representation not only enriches a framework, Hesse’s, of enduring relevance for understanding scientific activity, but may offer something akin to a proof of concept of it. (shrink)

Arguments from non-causal analogy form a distinctive class of analogical arguments in science not recognized in authoritative classifications by, e.g., Hesse and Bartha. In this paper, I illustrate this novel class of scientific analogies by means of historical examples from physics, biology and economics, at the same time emphasizing their broader significance for contemporary debates in epistemology.

Although the recent emphasis on models in philosophy of science has been an important development, the consequence has been a shift away from more traditional notions of theory. Because the semantic view defines theories as families of models and because much of the literature on “scientific” modeling has emphasized various degrees of independence from theory, little attention has been paid to the role that theory has in articulating scientific knowledge. This paper is the beginning of what I hope will be (...) a redress of the imbalance. I begin with a discussion of some of the difficulties faced by various formulations of the semantic view not only with respect to their account of models but also with their definition of a theory. From there I go on to articulate reasons why a notion of theory is necessary for capturing the structure of scientific knowledge and how one might go about formulating such a notion in terms of different levels of representation and explanation. The context for my discussion is the BCS account of superconductivity, a `theory' that was, and still is, sometimes referred to as a `model'. BCS provides a nice focus for the discussion because it illuminates various features of the theory/model relationship that seem to require a robust notion of theory that is not easily captured by the semantic account. (shrink)

Mary Hesse's well-known work on models and analogies gives models a creative role to play in science, which rests on developing certain analogical properties considered neutral between the two fields. Case study material from Irving Fisher's work (The Purchasing Power of Money, 1911), in which he used analogies to construct models of monetary relations and the monetary system, highlights certain omissions in Hesse's account. The analysis points to the importance of taking account of the negative properties in the analogies and (...) to certain differences between "ready-made" analogies (models of systems based on existing analogical structures) and "designed" analogies (models built up from separate analogical features). (shrink)

The provocative paper by John Forrester ‘If p, Then What? Thinking in Cases’ opened up the question of case thinking as a separate mode of reasoning in the sciences. Case-based reasoning is certainly endemic across a number of sciences, but it has looked different according to where it has been found. This article investigates this mode of science – namely thinking in cases – by questioning the different interpretations of ‘If p?’ and exploring the different interpretative responses of what follows (...) in ‘Then What?’. The aim is to characterize how ‘reasoning in, within, with, and from cases’ forms a mode of scientific investigation for single cases, for runs of cases, and for comparative cases, drawing on materials from a range of different fields in which case-based reasoning appears. (shrink)

Modelling became one of the primary tools of mathematical economic research in the twentieth century, but when we look at examples of how nonanalogical models were first built in economics, both the process of making representations and aspects of the representing relation remain opaque. Like early astronomers, economists have to imagine how the hidden parts of their world are arranged and to make images, that is, create models, to represent how they work. The case of the Edgeworth Box, a model (...) widely used for theoretical work in twentieth-century economics, provides a good example to explore the process of making mathematical representations of the economy. It shows how, in making these new representations, conceptual elements were developed which could not have been represented in the older verbal forms of economics. (shrink)

Is rhetoric just a new and trendy way toépater les bourgeois?Unfortunately, I think that the newfound interest of some economists in rhetoric, and particularly Donald McCloskey in his new book and subsequent responses to critics, gives that impression. After economists have worked so hard for the past five decades to learn their sums, differential calculus, real analysis, and topology, it is a fair bet that one could easily hector them about their woeful ignorance of the conjugation of Latin verbs or (...) Aristotle's Six Elements of Tragedy. Moreover, it has certainly become an academic cliché that economists write as gracefully and felicitously as a hundred monkeys chained to broken typewriters. The fact that economists still trot out Keynes's prose in their defense is itself an index of the inarticulate desperation of an inarticulate profession. (shrink)

It is now a widespread opinion among interpreters that Aristotle’s History of Animals is not a mere collection of empirical data but has its own theoretical framework; however, there is still disagreement as to exactly what this framework is. To address the problem, the article analyzes in detail the diairetic schemes of HA I 1, attempting to overturn the common opinion that this chapter is a mere expository introduction to the study of animals’ differences. On the contrary, it will be (...) shown that in this chapter Aristotle not only applies the method of ‘multiple division’ theorized in Parts of Animals I 2–4, but also uses dividing criteria that are informed by his causal theory and his hylomorphist ontology. This analysis will therefore lead to the more controversial conclusion that HA is not an ‘early’ work by Aristotle but a mature treatise with its own specific theoretical aim: the aitiological explanation of the anatomical, eco-physiological and ethological differences among animals. (shrink)

Meynell’s contention is that feminists should attend to pictures in science as distinctive bearers of epistemic content that cannot be reduced to propositions. Remarks on the practice and function of medical illustration—specifically, images Nancy Tuana used in her discussion of the construction of ignorance of women’s sexual function (2004)—show pictures to be complex and powerful epistemic devices. Their affinity with perennial feminist concerns, the relation between epistemic subject and object, and the nature of social knowledge, are of particular interest.

Presented here is an overview from the standpoints of sociology, history of science, philosophy of science and “pure science” of the lingering question of whether sociology is a form of scientific pursuit. The conclusion is drawn that sociology barely meets any of the rigid criteria traditionally associated with the natural sciences. Sociology is viewed as having a position of theory and argument which is labeled “inconoclastic scepticism.”.

Koriat & Goldsmith's thesis is provocative but has three problems: First, quantity and accuracy are not simply related, they are complementary. Second, the storehouse metaphor is not the driving force behind contemporary theories of memory and may not be viable. Third, the taxonomy is incomplete, leaving unclassified several extremely influential methods and measures, such as priming and response latency.

This commentary deals with criteria for assigning truth values to memory contents. A parallel with perception shows how truth values can be assigned by considering subjects' beliefs about the truth state of the memory content. This topic is also relevant to the study of processes of control over retrieval.

The value of accuracy and quantity as memory measures is assessed. It is argued that (1) accuracy does not measure correspondence (monitoring) because it ignores omissions and correct rejections, (2) quantity is confounded with monitoring in recall, and (3) in recognition, if targets and foils are unequal, both measures, even together, still ignore correct rejections.

Over the last few decades, theoretical discussions about metaphors have appeared with increasing frequency in the literature and, during the last fifteen years or so, such discussions have become more and more common in the methodology of economics. But what exactly is a metaphor? According to a tradition which dates back to Aristotle, a metaphor is the attribution to one object, A, of the name of another object, B, while this name or these qualities do not properly or normally belong (...) to A. Thus, a metaphor is present when a term used to describe A is a term which is already commonly used to name B. Defined in such a way, one must admit that metaphors are frequently found in economics as well as in other sciences. Let us consider, for example, a term like ‘elasticity’ which is extensively used by economists. According to the ordinary dictionary definition, this word designates a property of bodies by which they recover their initial form after having been submitted to a pressure; in a less technical sense, it refers to the flexibility of some bodies or to their responsiveness to pressures. (shrink)

In this paper I demonstrate how certain contemporary atheists have problematically conflatedatheismwithagnosticism(knowingly or unknowingly). The first type of conflation issemantic fusion, where the lack of belief in God is combined with the outright denial of God, under the single label of ‘atheism’. The second ismorphological fissionwhich involves the separation of atheism into two subcategories where lack of belief in God is labelled asnegativeatheism and outright denial of God aspositiveatheism – and while here they are more explicitly demarcated, they are still (...) positioned under the broad notion of atheism. I argue in this paper that atheism should be better used as thepropositional denialof God and thatuncertaintyandunknowability about Godshould be reserved to characterise agnosticism. Conflating these positions under the single term ‘atheism’ mischaracterises agnostics and inflates the territory of atheists. In clarifying these terms, I review how the nuances in the prefixa-in atheism have potentially contributed towards these misnomers. I also suggest the use of the categories ‘local atheism’ and ‘global atheism’ to clarify on whom the burden of proof lies within the discourse. (shrink)

In place of earlier instrumentalist and phenomenalist interpretations of science both Quine and Sellars have developed highly influential realist positions centering around the doctrine that accepting a theory as explanatory and irreducible rationally entails accepting the entities posited by the theory. A growing reaction against this realism is partially based on perceived inadequacies in the doctrines of Quine and Sellars, but even more on reconstructions of scientific explanations which do not involve such ontic commitments. Three types of anti-realistic positions are (...) considered and criticized. Hesse's neo-Duhemian position couples a statistical theory of inference to a downgrading of purely theoretical statements. Sneed uses the method of axiomatrization through set-theoretic predicates to supply a reconstruction of Kuhn's account of scientific development. Here Ramsey-reduction sentences serve to eliminate purely theoretical terms. The longest section deals with van Fraassen's semantic model based on a state-space representation of scientific theories and the use of this model in interpreting quantum mechanics. It is argued that the model is valuable, but that the anti-realist interpretation accorded it is not justified and entails serious inconsistencies. (shrink)

The purpose of this paper is to analyze the structure and the defeasibility conditions of argument from analogy, addressing the issues of determining the nature of the comparison underlying the analogy and the types of inferences justifying the conclusion. In the dialectical tradition, different forms of similarity were distinguished and related to the possible inferences that can be drawn from them. The kinds of similarity can be divided into four categories, depending on whether they represent fundamental semantic features of the (...) terms of the comparison or non-semantic ones, indicating possible characteristics of the referents. Such distinct types of similarity characterize different kinds of analogical arguments, all based on a similar general structure, in which a common genus is abstracted. Depending on the nature of the abstracted common feature, different rules of inference will apply, guaranteeing the attribution of the analogical predicate to the genus and to the primary subject. This analysis of similarity and the relationship thereof with the rules of inference allows a deeper investigation of the defeasibility conditions. (shrink)

The question is discussed how noise gained a functional meaning in the context of biology. According to the common view, noise is considered a disturbance or perturbation. I analyze how this understanding changed and what kind of developments during the last 10 years contributed to the emergence of a new understanding of noise. Results gained during a field study in a synthetic biology laboratory show that the emergence of this new research discipline—its highly interdisciplinary character, its new technologies and novel (...) modeling strategies—provided essential impulses, which led to the observed change in the concept of noise. The laboratory study is combined with a historical analysis, which explores the general question as to how concepts travel between disciplines and, specifically, how noise was transferred from engineering and physics into biology. In the past, scientists, such as Lotka and Goodwin, tried to introduce a statistical mechanics into biology and discussed the problem of “unfitting” concepts. The change in the meaning of the concept can be interpreted as a way of making it fit to the novel context in which it is applied. (shrink)

This article argues for an anti-deflationist view of scientific representation. Our discussion begins with an analysis of the recent Callender–Cohen deflationary view on scientific representation. We then argue that there are at least two radically different ways in which a thing can be represented: one is purely symbolic, and therefore conventional, and the other is epistemic. The failure to recognize that scientific models are epistemic vehicles rather than symbolic ones has led to the mistaken view that whatever distinguishes scientific models (...) from other representational vehicles must merely be a matter of pragmatics. It is then argued that even though epistemic vehicles also contain conventional elements, they do their job of demonstration in spite of such elements. (shrink)

The paper, as Part I of a two-part series, argues for a hybrid formulation of the semantic view of scientific theories. For stage-setting, it first reviews the elements of the model theory in mathematical logic (on whose foundation the semantic view rests), the syntactic and the semantic view, and the different notions of models used in the practice of science. The paper then argues for an integration of the notions into the semantic view, and thereby offers a hybrid semantic view, (...) which at once secures the view's logical foundations and enhances its applicability. The dilemma of either losing touch with the practice of science or yielding up the benefits of the model theory is thus avoided. (shrink)

In this paper, a criticism of the traditional theories of approximation and idealization is given as a summary of previous works. After identifying the real purpose and measure of idealization in the practice of science, it is argued that the best way to characterize idealization is not to formulate a logical model – something analogous to Hempel's D-N model for explanation – but to study its different guises in the praxis of science. A case study of it is then made (...) in thermostatistical physics. After a brief sketch of the theories for phase transitions and critical phenomena, I examine the various idealizations that go into the making of models at three difference levels. The intended result is to induce a deeper appreciation of the complexity and fruitfulness of idealization in the praxis of model-building, not to give an abstract theory of it. (shrink)

Mathematical models and their modeling frameworks developed to advance knowledge in one discipline are sometimes sourced to answer questions or solve problems in another discipline. Studying this aspect of cross-disciplinary transfer of knowledge objects, philosophers of science have weighed in on the question of whether knowledge about how a mathematical model is previously applied in one discipline is necessary for the success of reapplying said model in a different discipline. However, not much has been said about whether the answer to (...) that epistemological question applies to the reapplication of a modeling framework. More generally, regarding the nature of the production of knowledge in science, a metaphysical question remains to be explored whether historical contingencies associated with a mathematical construct have a genuine impact on the nature—as opposed to sociological practices or individual psychology—of advancing scientific knowledge with said construct. Focusing on this metaphysical question, this paper analyzes the use of mathematical logic in the development of the Chomsky hierarchy and subsequent reapplications of said hierarchy; with these examples, this paper develops the notion of “spillovers” as a way to detect cross-disciplinary justifications for better understanding the relations between reapplications of the same mathematical construct across disciplines. (shrink)

Nineteenth and twentieth century philosophies of science have consistently failed to identify any rational basis for the compelling character of scientific analogies. This failure is particularly worrisome in light of the fact that the development and diffusion of certain scientific analogies, e.g. Darwin’s analogy between domestic breeds and naturally occurring species, constitute paradigm cases of good science. It is argued that the interactivist model, through the notion of a partition epistemology, provides a way to understand the persuasive character of compelling (...) scientific analogies without consigning them to an irrational or arational context of discovery. (shrink)

Speaking: from Intention to Articulation Willem J. M. Levelt, 1989 (1993 paperback) Cambridge, MA: MIT Press ISBN: 0–262–12137–9(hb), 0–262–62089–8(pb)Rules for Reasoning Richard E. Nisbett (Ed.), 1993 Hillsdale, NJ, Lawrence Erlbaum Associates ISBN: 0–8058–1256–3(hb), 0–8085–1257–1 (pb)Readings in Philosophy and Cognitive Science Alvin I. Goldman, 1993 Cambridge, MA, MIT Press ISBN: 0–262–07153–3(hb), 0–262–57100–5(pb)Language Comprehension in Ape and Child, Monographs of the Society for Research in Child Development, Serial No. 233, Vol. 58, Nos 3–4 Sue Savage‐Rumbaugh, Jeannine Murphy, Rose A. Sevcik, Karen E. (...) Brakke, Shelly L. Williams & Duane M. Rumbaugh, with commentary by Elizabeth Bates, and a reply by the authors, 1993 Chicago: University of Chicago Press ISBN: 0–226–73542–7Language, Music and Mind Diana Raffman, 1993 Cambridge, MIT Press/Bradford Books ISBN: 0–262–18150–9Psychology of Proof Lance J. Rips, 1994 Cambridge, MA, MIT Press ISBN: 0–262–18153–3Human and Machine Thinking P. Johnson‐Laird, 1993 Hillsdale, NJ, Erlbaum ISBN: 0–8058–0921‐XIntelligent Behavior in Animals and Robots David McFarland & Thomas Bosser, 1993 Cambridge, MA and London, UK: MIT Press/ Bradford Books ISBN: 0–262–13293–1The Eye and the Mind: Reflections on Perception and the Problem of Knowledge Charles Landesman, 1993 Dordrecht: Kluwer Academic Publishers ISBN: 0–7923–2586–9The Moral Self GilG. Noam & Thomas E. Wren (Eds), in cooperation with Gertud Nunner‐Winkler & Wolfgang Edelstein, 1993 Cambridge, MA: MIT Press ISBN: 0–262–14052–1The Logic of Discovery: A Theory of the Rationality of Scientific Research Scott A. Kleiner, 1993 Dordrecht: Kluwer Academic Publishers ISBN: 0–7923–2371–8Folk Psychology and the Philosophy of Mind S.M. Christenson & D.R. Turner (Eds), 1993 Hillsdale, NJ: Lawrence Erlbaum ISBN: 0–805–80931–7. (shrink)

The concepts and powerful mathematical tools of Dynamical Systems Theory (DST) yield illuminating methods of studying cognitive processes, and are even claimed by some to enable us to bridge the notorious explanatory gap separating mind and matter. This article includes an analysis of some of the conceptual and empirical progress Dynamical Systems Theory is claimed to accomodate. While sympathetic to the dynamicist program in principle, this article will attempt to formulate a series of problems the proponents of the approach in (...) question will need to face if they wish to prolong their optimism. The main points to be addressed involve the reductive tendencies inherent in Dynamical Systems Theory, its somewhat muddled position relative to connectionism, the metaphorical nature DST-C exhibits which hinders its explanatory potential, and DST-C's problematic account of causality. Brief discussions of the mathematical and philosophical backgrounds of DST, seminal experimental work and possible adaptations of the theory or alternative suggestions (dynamicist connectionism, neurophenomenology, R&D theory) are included. (shrink)

The correspondence view of memory is not a metaphor. However, correspondence is the essential feature of the archaeology metaphor, which harks back to Freud and Neisser. A modern version of this metaphor and some of its implications are briefly described. The archaeology metaphor integrates the idea of stored traces in a nonmechanistic framework.

While there are many examples of metaphysical theorising being heuristically and intellectually important in the progress of scientific knowledge, many people wonder how metaphysics not closely informed and inspired by empirical science could lead to rival or even supplementary knowledge about the world. This paper assesses the merits of a popular defence of the a priori methodology of metaphysics that goes as follows. The first task of the metaphysician, like the scientist, is to construct a hypothesis that accounts for the (...) phenomena in question. It is then argued that among the possible metaphysical theories, the empirical evidence underdetermines the right one, just as the empirical evidence underdetermines the right scientific theory. In the latter case it is widely agreed that we must break the underdetermination by appeal to theoretical virtues, and this is just what should be and largely is done in metaphysics. This is part of a more general line of argument that defends metaphysics on the basis of its alleged continuity with highly theoretical science. In what follows metaphysics and theoretical science are compared in order to see whether the above style of defence of a priori metaphysics is successful. (shrink)

In this paper, I take a critical look at the Davidsonian argument that metaphorical sentences do not express propositions because of the phenomenological experience—seeing one thing as another thing—involved in understanding them as metaphors. According to Davidson, seeing-as is not seeing-that. This verdict is aimed at dislodging metaphor from the position of being assessed with the semantic notions of propositions, meaning, and truth. I will argue that the phenomenological or perceptual experience associated with metaphors does not determine the propositional contentfulness (...) or truth-evaluability of metaphors. Truth-evaluability is not inconsistent but compatible with a perceptual model for metaphors. I argue for this partly by showing that seeing-as does not constitute understanding of metaphors when understanding is appropriately construed in terms of being able to use an expression. (shrink)

In this paper, I take a critical look at the Davidsonian argument that metaphorical sentences do not express propositions because of the phenomenological experience—seeing one thing as another thing—involved in understanding them as metaphors. According to Davidson, seeing-as is not seeing-that. This verdict is aimed at dislodging metaphor from the position of being assessed with the semantic notions of propositions, meaning, and truth. I will argue that the phenomenological or perceptual experience associated with metaphors does not determine the propositional contentfulness (...) or truth-evaluability of metaphors. Truth-evaluability is not inconsistent but compatible with a perceptual model for metaphors. I argue for this partly by showing that seeing-as does not constitute understanding of metaphors when understanding is appropriately construed in terms of being able to use an expression. (shrink)

In this paper, I take a critical look at the Davidsonian argument that metaphorical sentences do not express propositions because of the phenomenological experience—seeing one thing as another thing—involved in understanding them as metaphors. According to Davidson, seeing-as is not seeing-that. This verdict is aimed at dislodging metaphor from the position of being assessed with the semantic notions of propositions, meaning, and truth. I will argue that the phenomenological or perceptual experience associated with metaphors does not determine the propositional contentfulness (...) or truth-evaluability of metaphors. Truth-evaluability is not inconsistent but compatible with a perceptual model for metaphors. I argue for this partly by showing that seeing-as does not constitute understanding of metaphors when understanding is appropriately construed in terms of being able to use an expression. (shrink)

In contrast to its aims, Koriat & Goldsmith's article vividly demonstrates(1) the complementarity of ecological and traditional approaches and (2) the difficulty of characterising the growing diversity of memory research with a single set of distinctions. Moreover, the contrast between correspondence and storehouse metaphors is important enough to stand alone without reference to an everyday/laboratory controversy, which is neither acute nor necessary.

The novel correspondence metaphor outlined by Koriat & Goldsmith offers important advantages for studying critical issues of memory-accuracy. It also fits well with the current emphasis on the reconstructive nature of memory and on the role of cognitive, metacognitive, and motivational factors in memory performance. These positive features notwithstanding, the storehouse/correspondence framework faces potential perils having to do with its implied linkage to the laboratory/real-life controversy and its proposal of studying correspondence issues in isolation from memory phenomena captured by the (...) storehouse paradigm. (shrink)

Structural analogies between physical laws have received considerable attention from philosospheres of science. This paper, however, focusses on structural analogies between physical systems; this type of analogy plays an important role in the physical and technological sciences. A formal, set-theoretic description of structural analogies between physical systems is presented, and it is shown that a structural analogy between systems does not require a structural analogy with regard to the laws involved, nor conversely.

This two-part article presents the research program for a theory and empirical analysis of religious evolution. It is assumed that religion isprimarilya co-evolution to societal evolution, which in turn is a co-evolution to mental, organic, and physical evolution. The theory of evolution is triangulated with the systems theory and the semiotically informed theory of communication, so that knowledge can be gained that would not be acquired by only one of the three theories: The differentiation between religion and its environment can (...) be reconstructed based on the theory of evolution. The elements of the theory of evolution can be understood as the formation of systems. The semiotically informed theory of communication clarifies the conditions of the combination of both the systems theory and the theory of evolution as well as its objects. In turn, the combination of the systems theory and the theory of evolution can describe how communication—including religion and science—evolves and is structured. (shrink)

Our response to the commentators covers four general issues: (1) How useful is our proposed conceptualization of the real-life/laboratory controversy in terms of the contrast between the correspondence and storehouse metaphors? (2) What is the relationship between these two metaphors? (3) What are the unique implications of the correspondence metaphor for memory assessment and theory? (4) What are the nature and role of memory metaphors in memory research? We stress that the correspondence metaphor can be usefully exploited independent of the (...) real-life/laboratory controversy, but that a variety of other metaphors, including the storehouse, should also be utilized in order to more fully capture the myriad facets and functions of memory in everyday life. (shrink)

The study of memory is witnessing a spirited clash between proponents of traditional laboratory research and those advocating a more naturalistic approach to the study of “real-life” or “everyday” memory. The debate has generally centered on the “what” (content), “where” (context), and “how” (methods) of memory research. In this target article, we argue that the controversy discloses a further, more fundamental breach between two underlying memory metaphors, each having distinct implications for memory theory and assessment: Whereas traditional memory research has (...) been dominated by thestorehousemetaphor, leading to a focus on thenumberof items remaining in store and accessible to memory, the recent wave of everyday memory research has shifted toward acorrespondencemetaphor, focusing on theaccuracyof memory in representing past events. The correspondence metaphor calls for a research approach that differs from the traditional one in important respects: in emphasizing the intentional –representational function of memory, in addressing the wholistic and graded aspects of memory correspondence, in taking an output-bound assessment perspective, and in allowing more room for the operation of subject-controlled metamemory processes and motivational factors. This analysis can help tie together soine of the what, where, and how aspects of the “real-life/laboratory” controversy. More important, however, by explicating the unique metatheoretical foundation of the accuracy-oriented approach to memory we aim to promote a more effective exploitation of the correspondence metaphor inbothnaturalistic and laboratory research contexts. (shrink)

The use of idealized models in science is by now well-documented. Such models are typically constructed in a “top-down” fashion: starting with an intractable theory or law and working down toward the phenomenon. This view of model-building has motivated a family of confirmation schemes based on the convergence of prediction and observation. This paper considers how chaotic dynamics blocks the convergence view of confirmation and has forced experimentalists to take a different approach to model-building. A method known as “phase space (...) reconstruction” not only reveals a lacuna in the philosophical literature on models, it also fails to conform to conventional views about how models are used to confirm a theory. (shrink)

The picture of synthetic biology as a kind of engineering science has largely created the public understanding of this novel field, covering both its promises and risks. In this paper, we will argue that the actual situation is more nuanced and complex. Synthetic biology is a highly interdisciplinary field of research located at the interface of physics, chemistry, biology, and computational science. All of these fields provide concepts, metaphors, mathematical tools, and models, which are typically utilized by synthetic biologists by (...) drawing analogies between the different fields of inquiry. We will study analogical reasoning in synthetic biology through the emergence of the functional meaning of noise, which marks an important shift in how engineering concepts are employed in this field. The notion of noise serves also to highlight the differences between the two branches of synthetic biology: the basic science-oriented branch and the engineering-oriented branch, which differ from each other in the way they draw analogies to various other fields of study. Moreover, we show that fixing the mapping between a source domain and the target domain seems not to be the goal of analogical reasoning in actual scientific practice. (shrink)