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  1. Vulnerability, Insecurity and the Pathologies of Trust and Distrust.Catriona Mackenzie - 2020 - International Journal of Philosophical Studies:624-643.
    While some trust theorists have adverted to the vulnerabilities involved in trust, especially vulnerability to betrayal, the literature on trust has not engaged with recent work on the ethics of vulnerability. This paper initiates a dialogue between these literatures, and in doing so begins to explore the complex interrelations between vulnerability and trust. More specifically, it aims to show how trust can both mitigate and compound vulnerability. Through a discussion of two examples drawn from literary sources, the paper also investigates (...)
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  • Why bioethics needs a concept of vulnerability.Wendy Rogers, Catriona Mackenzie & Susan Dodds - 2012 - International Journal of Feminist Approaches to Bioethics 5 (2):11-38.
    Concern for human vulnerability seems to be at the heart of bioethical inquiry, but the concept of vulnerability is under-theorized in the bioethical literature. The aim of this article is to show why bioethics needs an adequately theorized and nuanced conception of vulnerability. We first review approaches to vulnerability in research ethics and public health ethics, and show that the bioethical literature associates vulnerability with risk of harm and exploitation, and limited capacity for autonomy. We identify some of the challenges (...)
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  • Eschewing Definitions of the Therapeutic Misconception: A Family Resemblance Analysis.D. S. Goldberg - 2011 - Journal of Medicine and Philosophy 36 (3):296-320.
    Twenty-five years after the term "therapeutic misconception’ (TM) first entered the literature, most commentators agree that it remains widespread. However, the majority of scholarly attention has focused on the reasons why a patient cum human subject might confuse the goals of research with the goals of therapy. Although this paper addresses the social and cultural factors that seem to animate the TM among subjects, it also fills a niche in the literature by examining why investigators too might operate under a (...)
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  • Vulnerability in research and health care; describing the elephant in the room?Samia A. Hurst - 2008 - Bioethics 22 (4):191–202.
    Despite broad agreement that the vulnerable have a claim to special protection, defining vulnerable persons or populations has proved more difficult than we would like. This is a theoretical as well as a practical problem, as it hinders both convincing justifications for this claim and the practical application of required protections. In this paper, I review consent-based, harm-based, and comprehensive definitions of vulnerability in healthcare and research with human subjects. Although current definitions are subject to critique, their underlying assumptions may (...)
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  • Rethinking the Belmont Report?Phoebe Friesen, Lisa Kearns, Barbara Redman & Arthur L. Caplan - 2017 - American Journal of Bioethics 17 (7):15-21.
    This article reflects on the relevance and applicability of the Belmont Report nearly four decades after its original publication. In an exploration of criticisms that have been raised in response to the report and of significant changes that have occurred within the context of biomedical research, five primary themes arise. These themes include the increasingly vague boundary between research and practice, unique harms to communities that are not addressed by the principle of respect for persons, and how growing complexity and (...)
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  • (26 other versions)CQ Sources/Bibliography.Bette Anton - 1999 - Cambridge Quarterly of Healthcare Ethics 8 (4):348-350.
    These CQ Sources were compiled by Bette Anton.
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  • A Regulatory Argument Against Human Embryonic Stem Cell Research.S. Napier - 2009 - Journal of Medicine and Philosophy 34 (5):496-508.
    This article explores the plausibility of an argument against embryonic stem cell research based on what the regulations already say about research on pregnant women and fetuses. The center of the argument is the notion of vulnerability and whether such a concept is applicable to human embryos. It is argued that such an argument can be made plausible. The article concludes by responding to several important objections.
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  • IRBs and the Protection-Inclusion Dilemma: Finding a Balance.Phoebe Friesen, Luke Gelinas, Aaron Kirby, David H. Strauss & Barbara E. Bierer - 2022 - American Journal of Bioethics 23 (6):75-88.
    Institutional review boards, tasked with facilitating ethical research, are often pulled in competing directions. In what we call the protection-inclusion dilemma, we acknowledge the tensions IRBs face in aiming to both protect potential research participants from harm and include under-represented populations in research. In this manuscript, we examine the history of protectionism that has dominated research ethics oversight in the United States, as well as two responses to such protectionism: inclusion initiatives and critiques of the term vulnerability. We look at (...)
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  • Beyond Consent in Research.Emily Bell, Eric Racine, Paula Chiasson, Maya Dufourcq-Brana, Laura B. Dunn, Joseph J. Fins, Paul J. Ford, Walter Glannon, Nir Lipsman, Mary Ellen Macdonald, Debra J. H. Mathews & Mary Pat Mcandrews - 2014 - Cambridge Quarterly of Healthcare Ethics 23 (3):361-368.
    Abstract:Vulnerability is an important criterion to assess the ethical justification of the inclusion of participants in research trials. Currently, vulnerability is often understood as an attribute inherent to a participant by nature of a diagnosed condition. Accordingly, a common ethical concern relates to the participant’s decisionmaking capacity and ability to provide free and informed consent. We propose an expanded view of vulnerability that moves beyond a focus on consent and the intrinsic attributes of participants. We offer specific suggestions for how (...)
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  • Beyond Consent in Research.Emily Bell, Eric Racine, Paula Chiasson, Maya Dufourcq-Brana & Laura Macdonald - 2014 - Cambridge Quarterly of Healthcare Ethics 23 (3):361-368.
    Abstract:Vulnerability is an important criterion to assess the ethical justification of the inclusion of participants in research trials. Currently, vulnerability is often understood as an attribute inherent to a participant by nature of a diagnosed condition. Accordingly, a common ethical concern relates to the participant’s decisionmaking capacity and ability to provide free and informed consent. We propose an expanded view of vulnerability that moves beyond a focus on consent and the intrinsic attributes of participants. We offer specific suggestions for how (...)
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  • Patient Advocacy in Vascularized Composite Allotransplantation.James Benedict - 2022 - Frontiers in Psychology 13.
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  • The concept of vulnerability in aged care: a systematic review of argument-based ethics literature.Chris Gastmans, Roberta Sala & Virginia Sanchini - 2022 - BMC Medical Ethics 23 (1):1-20.
    BackgroundVulnerability is a key concept in traditional and contemporary bioethics. In the philosophical literature, vulnerability is understood not only to be an ontological condition of humanity, but also to be a consequence of contingent factors. Within bioethics debates, vulnerable populations are defined in relation to compromised capacity to consent, increased susceptibility to harm, and/or exploitation. Although vulnerability has historically been associated with older adults, to date, no comprehensive or systematic work exists on the meaning of their vulnerability. To fill this (...)
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  • (1 other version)Vulnerability of pregnant women in clinical research.Indira S. E. van der Zande, Rieke van der Graaf, Martijn A. Oudijk & Johannes J. M. van Delden - 2017 - Journal of Medical Ethics 43 (10):657-663.
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  • Ethical aspects of vulnerability in research.Elisabeth Weisser-Lohmann - 2012 - Poiesis and Praxis 9 (1):157-162.
    In connection with research on humans, the term “vulnerability” is only appropriate to identify the special need for protection of certain sections of the population and individuals, if this term refers to the additional risk of certain groups of subjects. Authors who focus on the additional risk suffering of a subject group when defining vulnerability succeed in considering the specific worthiness of protection in a context-sensitive way. The attempt to define the risk–benefit assessment for vulnerable subject groups on a binding (...)
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  • Mental health, big data and research ethics: Parity of esteem in mental health research from a UK perspective.Julie Morton & Michelle O’Reilly - 2019 - Clinical Ethics 14 (4):165-172.
    Central to ethical debates in contemporary mental health research are the rhetoric of parity of esteem, challenges underpinned by the social construct of vulnerability and the tendency to homogenis...
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  • (1 other version)Vulnerability of pregnant women in clinical research.Indira S. E. Van der Zande, Rieke van der Graaf, Martijn A. Oudijk & Johannes J. M. Van Delden - 2017 - Journal of Medical Ethics 43 (10):657-663.
    Background Notwithstanding the need to produce evidence-based knowledge on medications for pregnant women, they remain underrepresented in clinical research. Sometimes they are excluded because of their supposed vulnerability, but there are no universally accepted criteria for considering pregnant women as vulnerable. Our aim was to explore whether and if so to what extent pregnant women are vulnerable as research subjects. Method We performed a conceptual and empirical analysis of vulnerability applied to pregnant women. Analysis A conceptual analysis supports Hurst's definition (...)
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  • Health within illness: The negativity of vulnerability revised.Ivana Zagorac & Barbara Stamenković Tadić - 2022 - Medicine, Health Care and Philosophy 25 (2):207-217.
    This paper attempts to philosophically articulate empirical evidence on the positive effects of illness within the wider context of a discussion of the positive aspects of vulnerability. The conventional understanding holds that to be vulnerable is to be open to harms and wrongs; it is to be fragile, defenseless, and of compromised autonomy. In this paper, we challenge the assumption that vulnerability consists of nothing but powerlessness and dependence on others. This paper attempts to: (1) outline the theoretical conceptualisation of (...)
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  • (26 other versions)CQ Sources/Bibliography.Bette Anton - 2009 - Cambridge Quarterly of Healthcare Ethics 18 (2):155-158.
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