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The impending collapse of the whole-brain definition of death

In John P. Lizza (ed.), Defining the beginning and end of life: readings on personal identity and bioethics. Baltimore, Md: Johns Hopkins University Press. pp. 18-24 (2009)

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  1. Changing the Conversation About Brain Death.Robert D. Truog & Franklin G. Miller - 2014 - American Journal of Bioethics 14 (8):9-14.
    We seek to change the conversation about brain death by highlighting the distinction between brain death as a biological concept versus brain death as a legal status. The fact that brain death does not cohere with any biologically plausible definition of death has been known for decades. Nevertheless, this fact has not threatened the acceptance of brain death as a legal status that permits individuals to be treated as if they are dead. The similarities between “legally dead” and “legally blind” (...)
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  • Bioethics and the Culture Wars.Ana S. Iltis - 2011 - Christian Bioethics 17 (1):9-24.
    The term ‘culture wars’ has been used to describe deep, apparently intractable, disagreements between groups for many years. In contemporary discourse, it refers to disputes regarding significant moral matters carried out in the public square and for which there appears to be no way to achieve consensus or compromise. One set of battle lines is drawn between those who hold traditional Christian commitments and those who do not. Christian bioethics is nested in a set of moral and metaphysical understandings that (...)
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  • Reviving Brain Death: A Functionalist View. [REVIEW]Samuel H. LiPuma & Joseph P. DeMarco - 2013 - Journal of Bioethical Inquiry 10 (3):383-392.
    Recently both whole brain death (WBD) and higher brain death (HBD) have come under attack. These attacks, we argue, are successful, leaving supporters of both views without a firm foundation. This state of affairs has been described as “the death of brain death.” Returning to a cardiopulmonary definition presents problems we also find unacceptable. Instead, we attempt to revive brain death by offering a novel and more coherent standard of death based on the permanent cessation of mental processing. This approach (...)
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  • Death, dying and donation: organ transplantation and the diagnosis of death.I. H. Kerridge - 2002 - Journal of Medical Ethics 28 (2):89.
    Refusal of organ donation is common, and becoming more frequent. In Australia refusal by families occurred in 56% of cases in 1995 in New South Wales, and had risen to 82% in 1999, becoming the most important determinant of the country's very low organ donation rate .Leading causes of refusal, identified in many studies, include the lack of understanding by families of brain death and its implications, and subsequent reluctance to relegate the body to purely instrumental status. It is an (...)
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  • Agreeing to disagree: Indigenous pluralism from human rights to bioethics.Chris Durante - 2009 - Journal of Religious Ethics 37 (3):513-529.
    David Hollenbach, working within the context of human rights theory, has developed the notion of "indigenous pluralism" as a means of coping with the problems that arise when different religious traditions hold distinct or incompatible interpretations of human rights. It will be argued that indigenous pluralism is a theoretically and practically useful concept for bioethics as well and hence should be incorporated into bioethical methodology and processes of bioethical policy formation. Subsequently, the notion of indigenous pluralism will be discussed in (...)
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  • Inconsistency between the Circulatory and the Brain Criteria of Death in the Uniform Determination of Death Act.Alberto Molina-Pérez, James L. Bernat & Anne Dalle Ave - 2023 - Journal of Medicine and Philosophy 48 (5):422-433.
    The Uniform Determination of Death Act (UDDA) provides that “an individual who has sustained either (1) irreversible cessation of circulatory and respiratory functions or (2) irreversible cessation of all functions of the entire brain, including the brain stem, is dead.” We show that the UDDA contains two conflicting interpretations of the phrase “cessation of functions.” By one interpretation, what matters for the determination of death is the cessation of spontaneous functions only, regardless of their generation by artificial means. By the (...)
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  • The intractable problems with brain death and possible solutions.Ari R. Joffe, Gurpreet Khaira & Allan R. de Caen - 2021 - Philosophy, Ethics and Humanities in Medicine 16 (1):1-27.
    Brain death has been accepted worldwide medically and legally as the biological state of death of the organism. Nevertheless, the literature has described persistent problems with this acceptance ever since brain death was described. Many of these problems are not widely known or properly understood by much of the medical community. Here we aim to clarify these issues, based on the two intractable problems in the brain death debates. First, the metaphysical problem: there is no reason that withstands critical scrutiny (...)
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  • (3 other versions)Defining Death: Beyond Biology.John P. Lizza - 2018 - Diametros 55:1-19.
    The debate over whether brain death is death has focused on whether individuals who have sustained total brain failure have satisfied the biological definition of death as “the irreversible loss of the integration of the organism as a whole.” In this paper, I argue that what it means for an organism to be integrated “as a whole” is undefined and vague in the views of those who attempt to define death as the irreversible loss of the integration of the organism (...)
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  • How (not) to think of the ‘dead-donor’ rule.Adam Omelianchuk - 2018 - Theoretical Medicine and Bioethics 39 (1):1-25.
    Although much has been written on the dead-donor rule in the last twenty-five years, scant attention has been paid to how it should be formulated, what its rationale is, and why it was accepted. The DDR can be formulated in terms of either a Don’t Kill rule or a Death Requirement, the former being historically rooted in absolutist ethics and the latter in a prudential policy aimed at securing trust in the transplant enterprise. I contend that the moral core of (...)
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  • Doubts about Death: The Silence of the Institute of Medicine.Jerry Menikoff - 1998 - Journal of Law, Medicine and Ethics 26 (2):157-165.
    Traditionally, organ retrieval from cadavers has taken place only in cases where the declaration of death has occurred using “brain death” criteria. Under these criteria, specific tests are performed to demonstrate directly a lack of brain activity. Recently, as a result of efforts to increase organ procurement, attention has been directed at the use of so-called “non-heart-beating” donors : individuals who are declared dead not as a result of direct measurements of brain function, but rather as a result of the (...)
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  • Abortion and the Beginning and End of Human Life.Don Marquis - 2006 - Journal of Law, Medicine and Ethics 34 (1):16-25.
    How can the abortion issue be resolved? Many believe that the issue can be resolved if, and only if, we can determine when human life begins. Those opposed to abortion choice typically say that human life begins at conception. Many who favor abortion choice say that we will never know when human life begins. The importance of the when-does-human-life-begin issue is not so much argued for as it is taken to be self-evident. Furthermore, belief that this issue is fundamental is (...)
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  • “Brain Death,” “Dead,” and Parental Denial.John J. Paris, Brian M. Cummings & M. Patrick Moore - 2014 - Cambridge Quarterly of Healthcare Ethics 23 (4):371-382.
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  • Postmodern Personhood: A Matter of Consciousness.Ben A. Rich - 1997 - Bioethics 11 (3-4):206-216.
    The concept of person is integral to bioethical discourse because persons are the proper subject of the moral domain. Nevertheless, the concept of person has played no role in the prevailing formulation of human death because of a purported lack of consensus concerning the essential attributes of a person. Beginning with John Locke's fundamental proposition that person is a ‘forensic term’, I argue that in Western society we do have a consensus on at least one necessary condition for personhood, and (...)
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  • The ethics of donation and transplantation: are definitions of death being distorted for organ transplantation?Ari R. Joffe - 2007 - Philosophy, Ethics, and Humanities in Medicine 2:28.
    A recent commentary defends 1) the concept of 'brain arrest' to explain what brain death is, and 2) the concept that death occurs at 2–5 minutes after absent circulation. I suggest that both these claims are flawed. Brain arrest is said to threaten life, and lead to death by causing a secondary respiratory then cardiac arrest. It is further claimed that ventilation only interrupts this way that brain arrest leads to death. These statements imply that brain arrest is not death (...)
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  • Death and transplantation: Let's try to get things methodologically straight.Giovanni Boniolo - 2006 - Bioethics 21 (1):32–40.
    The purpose of this paper is methodological. I begin by showing the methodological frailties of both the heart and brain approach to the criteria of death used in connection with organ transplantation. I then clarify what a definition is. Finally, I propose to abandon the definition of death, and suggest a pragmatic definition of ‘explantability window’.
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  • Against abandoning the dead donor rule: reply to Smith.Adam Omelianchuk - 2023 - Journal of Medical Ethics 49 (10):715-716.
    Smith argues that death caused by transplant surgery will not harm permanently unconscious patients, because they will not suffer a setback to their interests in the context of donation. Therefore, so the argument goes, the dead donor rule can be abandoned, because requiring a death declaration before procurement does not protect any relevant interest from being thwarted. Smith contends that a virtue of his argument is that it avoids the controversies over defining and determining death. I argue that it does (...)
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  • Conscientious of the Conscious: Interactive Capacity as a Threshold Marker for Consciousness.David B. Fischer & Robert D. Truog - 2013 - American Journal of Bioethics Neuroscience 4 (4):26-33.
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  • Lockwood on human identity and the primitive streak.A. A. Howsepian - 1997 - Journal of Medical Ethics 23 (1):38-41.
    Michael Lockwood has recently concluded that it can be morally permissible to perform potentially damaging non-therapeutic experiments on live human (pre)embryos. The reasons he provides in support of this conclusion commit him inter alia to the following controversial theses: (i) an organism's potential for twinning bears critically on the identity conditions for that organism; and (ii) functionally intact mentality-mediating neurological structures play a critical role in establishing the identity conditions for human organisms. I argue that Lockwood has given us no (...)
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  • A New Defense of Brain Death as the Death of the Human Organism.Andrew McGee, Dale Gardiner & Melanie Jansen - 2023 - Journal of Medicine and Philosophy 48 (5):434-452.
    This paper provides a new rationale for equating brain death with the death of the human organism, in light of well-known criticisms made by Alan D Shewmon, Franklin Miller and Robert Truog and a number of other writers. We claim that these criticisms can be answered, but only if we accept that we have slightly redefined the concept of death when equating brain death with death simpliciter. Accordingly, much of the paper defends the legitimacy of redefining death against objections, before (...)
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  • Good and not so good medical ethics.Rosamond Rhodes - 2015 - Journal of Medical Ethics 41 (1):71-74.
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  • Maybe Whole-Brain Death Was Never the Point.Stephen S. Hanson - 2023 - American Journal of Bioethics Neuroscience 14 (3):277-279.
    As Nair-Collins and Joffe note, the concern that our tests for brain death do not successfully show that all brain functions have stopped is not new (Nair-Collins and Joffe 2023). As our abilities...
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  • Death pluralism: a proposal.Gonzalo Díaz-Cobacho, Alberto Molina-Pérez & David Rodríguez-Arias - 2023 - Philosophy, Ethics, and Humanities in Medicine 18 (1):1-12.
    The debate over the determination of death has been raging for more than fifty years. Since then, objections against the diagnosis of brain death from family members of those diagnosed as dead-have been increasing and are causing some countries to take novel steps to accommodate people’s beliefs and preferences in the determination of death. This, coupled with criticism by some academics of the brain death criterion, raises some questions about the issues surrounding the determination of death. In this paper, we (...)
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  • The Whole-Brain Concept of Death Remains Optimum Public Policy.James L. Bernat - 2006 - Journal of Law, Medicine and Ethics 34 (1):35-43.
    “Brain death,” the determination of human death by showing the irreversible loss of all clinical functions of the brain, has become a worldwide practice. A biophilosophical account of brain death requires four sequential tasks: agreeing on the paradigm of death, a set of preconditions that frame the discussion; determining the definition of death by making explicit the consensual concept of death; determining the criterion of death that proves the definition has been fulfilled by being both necessary and sufficient for death; (...)
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  • A dualist analysis of abortion: personhood and the concept of self qua experiential subject.K. E. Himma - 2005 - Journal of Medical Ethics 31 (1):48-55.
    There is no issue more central to the abortion debate than the controversial issue of whether the fetus is a moral person. Abortion-rights opponents almost universally claim that abortion is murder and should be legally prohibited because the fetus is a moral person at the moment of conception. Abortion-rights proponents almost universally deny the crucial assumption that the fetus is a person; on their view, whatever moral disvalue abortion involves does not rise to the level of murder and hence does (...)
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  • Minds, brains, and hearts: an empirical study on pluralism concerning death determination.Vilius Dranseika & Ivars Neiders - 2020 - Monash Bioethics Review 38 (1):35-48.
    Several authors in bioethics literature have expressed the view that a whole brain conception of death is philosophically indefensible. If they are right, what are the alternatives? Some authors have suggested that we should go back to the old cardiopulmonary criterion of death and abandon the so-called Dead Donor Rule. Others argue for a pluralist solution. For example, Robert Veatch has defended a view that competent persons should be free to decide which criterion of death should be used to determine (...)
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  • Why psychological accounts of personal identity can accept a brain death criterion and biological definition of death.David B. Hershenov - 2019 - Theoretical Medicine and Bioethics 40 (5):403-418.
    Psychological accounts of personal identity claim that the human person is not identical to the human animal. Advocates of such accounts maintain that the definition and criterion of death for a human person should differ from the definition and criterion of death for a human animal. My contention is instead that psychological accounts of personal identity should have human persons dying deaths that are defined biologically, just like the deaths of human animals. Moreover, if brain death is the correct criterion (...)
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  • Toward a General Theory of Persons.A. A. Howsepian - 2000 - Christian Bioethics 6 (1):15-35.
    The fundamental question I consider is the following: What is it that makes one thing a person and another thing not? I do not provide a complete answer; rather I begin to develop a framework for answering the question. In this essay I do the following: (1) distinguish between the powers possessed by persons and the constitutions of persons, and propose some metaphysical conjectures concerning the relationship between persons' powers and their constitutions; (2) propose for Christians, as well as for (...)
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  • Organ Donation, Brain Death and the Family: Valid Informed Consent.Ana S. Iltis - 2015 - Journal of Law, Medicine and Ethics 43 (2):369-382.
    I argue that valid informed consent is ethically required for organ donation from individuals declared dead using neurological criteria. Current policies in the U.S. do not require this and, not surprisingly, current practices inhibit the possibility of informed consent. Relevant information is withheld, opportunities to ensure understanding and appreciation are extremely limited, and the ability to make and communicate a free and voluntary decision is hindered by incomplete disclosure and other practices. Current practices should be revised to facilitate valid informed (...)
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  • Public Reason.Jonathan Quong - 2013 - Stanford Encyclopedia of Philosophy.
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  • The death of whole-brain death: The plague of the disaggregators, somaticists, and mentalists.Robert M. Veatch - 2005 - Journal of Medicine and Philosophy 30 (4):353 – 378.
    In its October 2001 issue, this journal published a series of articles questioning the Whole-Brain-based definition of death. Much of the concern focused on whether somatic integration - a commonly understood basis for the whole-brain death view - can survive the brain's death. The present article accepts that there are insurmountable problems with whole-brain death views, but challenges the assumption that loss of somatic integration is the proper basis for pronouncing death. It examines three major themes. First, it accepts the (...)
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  • Distinguishing Minimal Consciousness From Decisional Capacity: Clinical, Ethical, and Legal Implications.Ben A. Rich - 2013 - American Journal of Bioethics Neuroscience 4 (1):56-57.
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  • The Demise of Brain Death.Lukas J. Meier - 2022 - British Journal for the Philosophy of Science 73 (2):487-508.
    Fifty years have passed since brain death was first proposed as a criterion of death. Its advocates believe that with the destruction of the brain, integrated functioning ceases irreversibly, somatic unity dissolves, and the organism turns into a corpse. In this article, I put forward two objections against this assertion. First, I draw parallels between brain death and other pathological conditions and argue that whenever one regards the absence or the artificial replacement of a certain function in these pathological conditions (...)
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  • In Defense of Brain Death: Replies to Don Marquis, Michael Nair-Collins, Doyen Nguyen, and Laura Specker Sullivan.John P. Lizza - 2018 - Diametros 55:68-90.
    In this paper, I defend brain death as a criterion for determining death against objections raised by Don Marquis, Michael Nair-Collins, Doyen Nguyen, and Laura Specker Sullivan. I argue that any definition of death for beings like us relies on some sortal concept by which we are individuated and identified and that the choice of that concept in a practical context is not determined by strictly biological considerations but involves metaphysical, moral, social, and cultural considerations. This view supports acceptance of (...)
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  • Constructing the Legal Concept of Death: The Counterhegemonic Option.Miran Epstein - 2014 - American Journal of Bioethics 14 (8):45-47.
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  • The problematic symmetry between brain birth and brain death.D. G. Jones - 1998 - Journal of Medical Ethics 24 (4):237-242.
    The possible symmetry between the concepts of brain death and brain birth (life) is explored. Since the symmetry argument has tended to overlook the most appropriate definition of brain death, the fundamental concepts of whole brain death and higher brain death are assessed. In this way, a context is provided for a discussion of brain birth. Different writers have placed brain birth at numerous points: 25-40 days, eight weeks, 22-24 weeks, and 32-36 weeks gestation. For others, the concept itself is (...)
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  • In defense of a pluralistic policy on the determination of death.Ivars Neiders & Vilius Dranseika - 2018 - Ethics and Bioethics (in Central Europe) 8 (3-4):179-188.
    In his paper “The challenge of brain death for the sanctity of life ethic”, Peter Singer advocates two options for dealing with death criteria in a way that is compatible with efficient organ transplantation policy. He suggests that we should either redefine death as cortical death or go back to the old cardiopulmonary criterion and scrap the Dead Donor Rule. We welcome Singer’s line of argument but raise some concerns about the practicability of the two alternatives advocated by him. We (...)
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  • Diagnosing death 50 years after the Harvard brain death report.Francis J. O’Keeffe & George L. Mendz - 2021 - The New Bioethics 27 (1):46-64.
    More than 50 years after the publication of the Harvard Committee Report that sought to define death according to whole-brain function criteria, this document continues to generate a diversity of o...
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  • Mind Perception and Willingness to Withdraw Life Support.Jeffrey M. Rudski, Benjamin Herbsman, Eric D. Quitter & Nicole Bilgram - 2016 - Neuroethics 9 (3):235-242.
    Discussions of withdrawal of life support often revolve around a patient’s perceived level of suffering or lack of experience. Personhood, however, is often linked to personal agency. In the present study, 279 laypeople estimated the amount of agency and experience in hypothetical patients differing in degree of consciousness. Participants also indicated whether they would choose to maintain or terminate life support. Patients were more likely to terminate life support for a patient in a persistent vegetative state, followed by one with (...)
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  • Toward a Science of Brain Death.Andrew Peterson, Loretta Norton, Lorina Naci, Adrian M. Owen & Charles Weijer - 2014 - American Journal of Bioethics 14 (8):29-31.
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  • The Sources of Uncertainty in Disorders of Consciousness.L. Syd M. Johnson & Christos Lazaridis - 2018 - American Journal of Bioethics Neuroscience 9 (2):76-82.
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  • Rethinking “Disease”: a fresh diagnosis and a new philosophical treatment.Russell Powell & Eric Scarffe - 2019 - Journal of Medical Ethics 45 (9):579-588.
    Despite several decades of debate, the concept of disease remains hotly contested. The debate is typically cast as one between naturalism and normativism, with a hybrid view that combines elements of each staked out in between. In light of a number of widely discussed problems with existing accounts, some theorists argue that the concept of disease is beyond repair and thus recommend eliminating it in a wide range of practical medical contexts. Any attempt to reframe the ‘disease’ discussion should answer (...)
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  • On Life, Death, and Abortion.D. W. Haslett - 1996 - Utilitas 8 (2):159-189.
    Morally speaking, is abortion murder? This is what I am calling the ‘abortion problem’. I claim that neither pro-life nor pro-choice advocates have the correct solution; that the correct solution is instead one considered correct by relatively few people. But if this solution really is correct, then why, after years of intense debate, is this solution not more widely accepted? Many, no doubt, are precluded from accepting it by religious dogma. But others, I think, fail to arrive at a correct (...)
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  • Beyond Transplantation: Considering Brain Death as a Hard Clinical Endpoint.Michelle J. Clarke, Megan S. Remtema & Keith M. Swetz - 2014 - American Journal of Bioethics 14 (8):43-45.
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  • Ethics Consultation: Persistent Brain Death and Religion: Must a Person Believe in Death to Die?Jeffrey Spike & Jane Greenlaw - 1995 - Journal of Law, Medicine and Ethics 23 (3):291-294.
    We first heard about this case from nurses in one of our intensive care units while we were conducting an inservice. When the session was over, we discussed it between ourselves, and decided that it must have been misrepresented. The case had been presented as one of a teenager who was brain dead, had been so for six months, yet had been brought into the ICU for treatment. We have run into this before, we thought: medical professionals confusing brain death (...)
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  • Presidential address: Is the sanctity of life ethic terminally ill?Peter Singer - 1995 - Bioethics 9 (3):327–343.
    Our growing technical capacity to keep human beings alive has brought the sanctity of life ethic to the point of collapse. The shift to a concept of brain death was already an implicit abandonment of the traditional ethic, though this has only recently become apparent. The 1993 decision of the British House of Lords in the case of Anthony Bland is an even more decisive shift towards an ethic that does not ask or seek to preserve human life as such, (...)
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  • Metaphysics and morality at the boundaries of life.Philip Robichaud - 2006 - Journal of Medicine and Philosophy 31 (2):97 – 105.
    (2006). Metaphysics and Morality at the Boundaries of Life. Journal of Medicine and Philosophy: Vol. 31, No. 2, pp. 97-105.
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  • Structuring Conversations on the Fact and Fiction of Brain Death.Ben A. Rich - 2014 - American Journal of Bioethics 14 (8):31-33.
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  • Loss of faith in brain death: Catholic controversy over the determination of death by neurological criteria.David Albert Jones - 2012 - Clinical Ethics 7 (3):133-141.
    The diagnosis of death by neurological criteria (colloquially known as ‘brain death’) is accepted in some form in law and medical practice throughout the world, and has been endorsed in principle by the Catholic Church. However, the rationale for this acceptance has been challenged by the accumulation of evidence of integrated vital activity in bodies diagnosed dead by neurological criteria. This paper sets out 10 different Catholic responses to the current crisis of confidence and assesses them in relation to a (...)
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  • Tracing the Soul: Medical Decisions at the Margins of Life.Walter Glannon - 2000 - Christian Bioethics 6 (1):49-69.
    Most religious traditions hold that what makes one a person is the possession of a soul and that this gives one moral status. This status in turn gives persons interests and rights that delimit the set of actions that are permitted to be done to them. In this paper, I identify the soul with the capacity for consciousness and mental life and examine the ethical aspects of medical decision-making at the beginning and end of life in cases of patients who (...)
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