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  1. Instruments, agents, and artificial intelligence: novel epistemic categories of reliability.Eamon Duede - 2022 - Synthese 200 (6):1-20.
    Deep learning (DL) has become increasingly central to science, primarily due to its capacity to quickly, efficiently, and accurately predict and classify phenomena of scientific interest. This paper seeks to understand the principles that underwrite scientists’ epistemic entitlement to rely on DL in the first place and argues that these principles are philosophically novel. The question of this paper is not whether scientists can be justified in trusting in the reliability of DL. While today’s artificial intelligence exhibits characteristics common to (...)
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  • Homepage Eckhart Arnold.Eckhart Arnold (ed.) - 2001 - Munich: Preprint.
    This is my personal homepage. Find my philosophical papers under "Philosophy".
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  • Computer simulation and the philosophy of science.Eric Winsberg - 2009 - Philosophy Compass 4 (5):835-845.
    There are a variety of topics in the philosophy of science that need to be rethought, in varying degrees, after one pays careful attention to the ways in which computer simulations are used in the sciences. There are a number of conceptual issues internal to the practice of computer simulation that can benefit from the attention of philosophers. This essay surveys some of the recent literature on simulation from the perspective of the philosophy of science and argues that philosophers have (...)
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  • Evidence for personalised medicine: mechanisms, correlation, and new kinds of black box.Mary Jean Walker, Justin Bourke & Katrina Hutchison - 2019 - Theoretical Medicine and Bioethics 40 (2):103-121.
    Personalised medicine has been discussed as a medical paradigm shift that will improve health while reducing inefficiency and waste. At the same time, it raises new practical, regulatory, and ethical challenges. In this paper, we examine PM strategies epistemologically in order to develop capacities to address these challenges, focusing on a recently proposed strategy for developing patient-specific models from induced pluripotent stem cells so as to make individualised treatment predictions. We compare this strategy to two main PM strategies—stratified medicine and (...)
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  • Building Blocks in Search of a Theory: Primates and Philosophers: How Morality Evolved, Frans de Waal . Princeton, NJ: Princeton University Press, 2006, (209 pp; $22.95 hbk; ISBN 0691124477). [REVIEW]Tomislav Bracanović - 2007 - Biological Theory 2 (4):422-424.
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  • Knowledge Building Expertise: Nanomodellers’ Education as an Example.Suvi Tala - 2013 - Science & Education 22 (6):1323-1346.
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  • The Everyday World of Simulation Modeling: The Development of Parameterizations in Meteorology.Mikaela Sundberg - 2009 - Science, Technology, and Human Values 34 (2):162-181.
    This article explores the practice of simulation modeling by investigating how parameterizations are constructed and integrated into existing frameworks. Parameterizations are simplified process descriptions adapted for simulation models. On the basis of a study of meteorological research, the article presents predictive and representative construction as two different ways of developing parameterizations and the trade-offs involved in this work. Because the overall aim in predictive construction is to improve weather forecasts, the most practical solutions are chosen over the best theoretical solutions. (...)
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  • Creating Convincing Simulations in Astrophysics. [REVIEW]Mikaela Sundberg - 2012 - Science, Technology, and Human Values 37 (1):64-87.
    Numerical simulations have come to be widely used in scientific work. Like experiments, simulations generate large quantities of numbers that require analysis and constant concern with uncertainty and error. How do simulationists convince themselves, and others, about the credibility of output? The present analysis reconstructs the perspectives related to performing numerical simulations, in general, and the situations in which simulationists deal with uncertain output, in particular. Starting from a distinction between idealized and realistic simulations, the paper presents the principal methods (...)
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  • Why is There No Successful Whole Brain Simulation (Yet)?Klaus M. Stiefel & Daniel S. Brooks - 2019 - Biological Theory 14 (2):122-130.
    With the advent of powerful parallel computers, efforts have commenced to simulate complete mammalian brains. However, so far none of these efforts has produced outcomes close to explaining even the behavioral complexities of animals. In this article, we suggest four challenges that ground this shortcoming. First, we discuss the connection between hypothesis testing and simulations. Typically, efforts to simulate complete mammalian brains lack a clear hypothesis. Second, we treat complications related to a lack of parameter constraints for large-scale simulations. To (...)
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  • Why Computer Simulation Cannot Be an End of Thought Experimentation.N. K. Shinod - 2021 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 52 (3):431-453.
    Computer simulation and thought experiments seem to produce knowledge about the world without intervening in the world. This has called for a comparison between the two methods. However, Chandrasekharan et al. argue that the nature of contemporary science is too complex for using TEs. They suggest CS as the tool for contemporary sciences and conclude that it will replace TEs. In this paper, by discussing a few TEs from the history of science, I show that the replacement thesis about TE (...)
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  • Metaphysics within Chemical Physics: The Case of Ab Initio Molecular Dynamics. [REVIEW]Carsten Seck - 2012 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 43 (2):361-375.
    This paper combines naturalized metaphysics and a philosophical reflection on a recently evolving interdisciplinary branch of quantum chemistry, ab initio molecular dynamics. Bridging the gaps among chemistry, physics, and computer science, this cutting-edge research field explores the structure and dynamics of complex molecular many-body systems through computer simulations. These simulations are allegedly crafted solely by the laws of fundamental physics, and are explicitly designed to capture nature as closely as possible. The models and algorithms employed, however, involve many approximations and (...)
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  • Model Organisms as Scientific Representations.Lorenzo Sartori - forthcoming - British Journal for the Philosophy of Science.
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  • What is a Computer Simulation? A Review of a Passionate Debate.Nicole J. Saam - 2017 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 48 (2):293-309.
    Where should computer simulations be located on the ‘usual methodological map’ which distinguishes experiment from theory? Specifically, do simulations ultimately qualify as experiments or as thought experiments? Ever since Galison raised that question, a passionate debate has developed, pushing many issues to the forefront of discussions concerning the epistemology and methodology of computer simulation. This review article illuminates the positions in that debate, evaluates the discourse and gives an outlook on questions that have not yet been addressed.
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  • Approximations, idealizations and ‘experiments’ at the physics–biology interface.Darrell Patrick Rowbottom - 2008 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 42 (2):145-154.
    This paper, which is based on recent empirical research at the University of Leeds, the University of Edinburgh, and the University of Bristol, presents two difficulties which arise when condensed matter physicists interact with molecular biologists: the former use models which appear to be too coarse-grained, approximate and/or idealized to serve a useful scientific purpose to the latter; and the latter have a rather narrower view of what counts as an experiment, particularly when it comes to computer simulations, than the (...)
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  • The hermeneutics of ecological simulation.Steven L. Peck - 2008 - Biology and Philosophy 23 (3):383-402.
    Computer simulation has become important in ecological modeling, but there have been few assessments on how complex simulation models differ from more traditional analytic models. In Part I of this paper, I review the challenges faced in complex ecological modeling and how models have been used to gain theoretical purchase for understanding natural systems. I compare the use of traditional analytic simulation models and point how that the two methods require different kinds of practical engagement. I examine a case study (...)
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  • Evidence and Knowledge from Computer Simulation.Wendy S. Parker - 2020 - Erkenntnis 87 (4):1521-1538.
    Can computer simulation results be evidence for hypotheses about real-world systems and phenomena? If so, what sort of evidence? Can we gain genuinely new knowledge of the world via simulation? I argue that evidence from computer simulation is aptly characterized as higher-order evidence: it is evidence that other evidence regarding a hypothesis about the world has been collected. Insofar as particular epistemic agents do not have this other evidence, it is possible that they will gain genuinely new knowledge of the (...)
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  • Computing the uncomputable; or, The discrete charm of second-order simulacra.Matthew W. Parker - 2009 - Synthese 169 (3):447-463.
    We examine a case in which non-computable behavior in a model is revealed by computer simulation. This is possible due to differing notions of computability for sets in a continuous space. The argument originally given for the validity of the simulation involves a simpler simulation of the simulation, still further simulations thereof, and a universality conjecture. There are difficulties with that argument, but there are other, heuristic arguments supporting the qualitative results. It is urged, using this example, that absolute validation, (...)
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  • Building Simulations from the Ground Up: Modeling and Theory in Systems Biology.Miles MacLeod & Nancy J. Nersessian - 2013 - Philosophy of Science 80 (4):533-556.
    In this article, we provide a case study examining how integrative systems biologists build simulation models in the absence of a theoretical base. Lacking theoretical starting points, integrative systems biology researchers rely cognitively on the model-building process to disentangle and understand complex biochemical systems. They build simulations from the ground up in a nest-like fashion, by pulling together information and techniques from a variety of possible sources and experimenting with different structures in order to discover a stable, robust result. Finally, (...)
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  • Holism, entrenchment, and the future of climate model pluralism.Johannes Lenhard & Eric Winsberg - 2010 - Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics 41 (3):253-262.
    In this paper, we explore the extent to which issues of simulation model validation take on novel characteristics when the models in question become particularly complex. Our central claim is that complex simulation models in general, and global models of climate in particular, face a form of confirmation holism. This holism, moreover, makes analytic understanding of complex models of climate either extremely difficult or even impossible. We argue that this supports a position we call convergence skepticism: the belief that the (...)
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  • How Digital Computer Simulations Explain Real‐World Processes.Ulrich Krohs - 2008 - International Studies in the Philosophy of Science 22 (3):277 – 292.
    Scientists of many disciplines use theoretical models to explain and predict the dynamics of the world. They often have to rely on digital computer simulations to draw predictions fromthe model. But to deliver phenomenologically adequate results, simulations deviate from the assumptions of the theoretical model. Therefore the role of simulations in scientific explanation demands itself an explanation. This paper analyzes the relation between real-world system, theoretical model, and simulation. It is argued that simulations do not explain processes in the real (...)
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  • Epistemological Framework for Computer Simulations in Building Science Research: Insights from Theory and Practice.Amos Kalua & James Jones - 2020 - Philosophies 5 (4):30.
    Computer simulations are widely used within the area of building science research. Building science research deals with the physical phenomena that affect buildings, including heat and mass transfer, lighting and acoustic transmission. This wide usage of computer simulations, however, is characterized by a divergence in thought on the composition of an epistemological framework that may provide guidance for their deployment in research. This paper undertakes a fundamental review of the epistemology of computer simulations within the context of the philosophy of (...)
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  • The Elusive Basis of Inferential Robustness.James Justus - 2012 - Philosophy of Science 79 (5):795-807.
    Robustness concepts are often invoked to manage two obstacles confronting models of ecological systems: complexity and uncertainty. The intuitive idea is that any result derived from many idealized but credible models is thereby made more reliable or is better confirmed. An appropriate basis for this inference has proven elusive. Here, several representations of robustness analysis are vetted, paying particular attention to complex models of ecosystems and the global climate. The claim that robustness is itself confirmatory because robustness analysis employs a (...)
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  • Modeling molecules: Computational nanotechnology as a knowledge community.Ann Johnson - 2009 - Perspectives on Science 17 (2):pp. 144-173.
    I propose that a sociological and historical examination of nanotechnologists can contribute more to an understanding of nanotechnology than an ontological definition. Nanotechnology emerged from the convergent evolution of numerous "technical knowledge communities"-networks of tightly-interconnected people who operate between disciplines and individual research groups. I demonstrate this proposition by sketching the co-evolution of computational chemistry and computational nanotechnology. Computational chemistry arose in the 1950s but eventually segregated into an ab initio, basic research, physics-oriented flavor and an industry-oriented, molecular modeling and (...)
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  • Computer Image Processing: An Epistemological Aid in Scientific Investigation.Vincent Israel-Jost - 2016 - Perspectives on Science 24 (6):669-695.
    In many scientific fields, today’s practices of empirical enquiry rely heavily on the production of images that display the investigated phenomena. And while scientific images of phenomena have been important for a long time, what is striking now is that scientists have found ways to visualize such widely different types of phenomena. In the past twenty or thirty years, we have become accustomed to seeing images of galaxies, of cells, of the human brain but also of blood flow or of (...)
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  • The philosophy of simulation: hot new issues or same old stew?Roman Frigg & Julian Reiss - 2009 - Synthese 169 (3):593-613.
    Computer simulations are an exciting tool that plays important roles in many scientific disciplines. This has attracted the attention of a number of philosophers of science. The main tenor in this literature is that computer simulations not only constitute interesting and powerful new science , but that they also raise a host of new philosophical issues. The protagonists in this debate claim no less than that simulations call into question our philosophical understanding of scientific ontology, the epistemology and semantics of (...)
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  • Computer Simulations as Experiments.Anouk Barberousse, Sara Franceschelli & Cyrille Imbert - 2009 - Synthese 169 (3):557 - 574.
    Whereas computer simulations involve no direct physical interaction between the machine they are run on and the physical systems they are used to investigate, they are often used as experiments and yield data about these systems. It is commonly argued that they do so because they are implemented on physical machines. We claim that physicality is not necessary for their representational and predictive capacities and that the explanation of why computer simulations generate desired information about their target system is only (...)
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  • Simulated experiments: Methodology for a virtual world.Winsberg Eric - 2003 - Philosophy of Science 70 (1):105-125.
    This paper examines the relationship between simulation and experiment. Many discussions of simulation, and indeed the term "numerical experiments," invoke a strong metaphor of experimentation. On the other hand, many simulations begin as attempts to apply scientific theories. This has lead many to characterize simulation as lying between theory and experiment. The aim of the paper is to try to reconcile these two points of viewto understand what methodological and epistemological features simulation has in common with experimentation, while at the (...)
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  • What is a Simulation Model?Juan M. Durán - 2020 - Minds and Machines 30 (3):301-323.
    Many philosophical accounts of scientific models fail to distinguish between a simulation model and other forms of models. This failure is unfortunate because there are important differences pertaining to their methodology and epistemology that favor their philosophical understanding. The core claim presented here is that simulation models are rich and complex units of analysis in their own right, that they depart from known forms of scientific models in significant ways, and that a proper understanding of the type of model simulations (...)
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  • Simulaciones computacionales: un análisis de dos concepciones antagónicas.Juan Manuel Duran - 2017 - Principia: An International Journal of Epistemology (April):125-140.
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  • Toward a Philosophy of Systems Biology.Jonathan F. Davies & Maureen A. O’Malley - 2007 - Biological Theory 2 (4):420-422.
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  • Building Blocks in Search of a Theory: Primates and Philosophers: How Morality Evolved Frans de Waal Princeton, NJ: Princeton University Press, 2006 (209 pp; $22.95 hbk; ISBN 0691124477). [REVIEW]Tomislav Bracanović - 2007 - Biological Theory 2 (4):422-424.
    A critical review of Frans de Waal's book on evolution of morality (Frans de Waal, Primates and Philosophers: How Morality Evolved, Princeton, NJ: Princeton University Press, 2006).
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  • Adding logic to the toolbox of molecular biology.Giovanni Boniolo, Marcello D’Agostino, Mario Piazza & Gabriele Pulcini - 2015 - European Journal for Philosophy of Science 5 (3):399-417.
    The aim of this paper is to argue that logic can play an important role in the “toolbox” of molecular biology. We show how biochemical pathways, i.e., transitions from a molecular aggregate to another molecular aggregate, can be viewed as deductive processes. In particular, our logical approach to molecular biology — developed in the form of a natural deduction system — is centered on the notion of Curry-Howard isomorphism, a cornerstone in nineteenth-century proof-theory.
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  • Polycratic hierarchies and networks: what simulation-modeling at the LHC can teach us about the epistemology of simulation.Florian J. Boge & Christian Zeitnitz - 2020 - Synthese 199 (1-2):445-480.
    Large scale experiments at CERN’s Large Hadron Collider rely heavily on computer simulations, a fact that has recently caught philosophers’ attention. CSs obviously require appropriate modeling, and it is a common assumption among philosophers that the relevant models can be ordered into hierarchical structures. Focusing on LHC’s ATLAS experiment, we will establish three central results here: with some distinct modifications, individual components of ATLAS’ overall simulation infrastructure can be ordered into hierarchical structures. Hence, to a good degree of approximation, hierarchical (...)
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  • Virtual Realism: Really Realism or only Virtually so? A Comment on D. J. Chalmers’s Petrus Hispanus Lectures.Claus Beisbart - 2019 - Disputatio 11 (55):297-331.
    What is the status of a cat in a virtual reality environment? Is it a real object? Or part of a fiction? Virtual realism, as defended by D. J. Chalmers, takes it to be a virtual object that really exists, that has properties and is involved in real events. His preferred specification of virtual realism identifies the cat with a digital object. The project of this paper is to use a comparison between virtual reality environments and scientific computer simulations to (...)
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  • How can computer simulations produce new knowledge?Claus Beisbart - 2012 - European Journal for Philosophy of Science 2 (3):395-434.
    It is often claimed that scientists can obtain new knowledge about nature by running computer simulations. How is this possible? I answer this question by arguing that computer simulations are arguments. This view parallels Norton’s argument view about thought experiments. I show that computer simulations can be reconstructed as arguments that fully capture the epistemic power of the simulations. Assuming the extended mind hypothesis, I furthermore argue that running the computer simulation is to execute the reconstructing argument. I discuss some (...)
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  • Social Epistemology and Validation in Agent-Based Social Simulation.David Anzola - 2021 - Philosophy and Technology 34 (4):1333-1361.
    The literature in agent-based social simulation suggests that a model is validated when it is shown to ‘successfully’, ‘adequately’ or ‘satisfactorily’ represent the target phenomenon. The notion of ‘successful’, ‘adequate’ or ‘satisfactory’ representation, however, is both underspecified and difficult to generalise, in part, because practitioners use a multiplicity of criteria to judge representation, some of which are not entirely dependent on the testing of a computational model during validation processes. This article argues that practitioners should address social epistemology to achieve (...)
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  • Structures in Real Theory Application: A Study in Feasible Epistemology.Robert H. C. Moir - 2013 - Dissertation, University of Western Ontario
    This thesis considers the following problem: What methods should the epistemology of science use to gain insight into the structure and behaviour of scientific knowledge and method in actual scientific practice? After arguing that the elucidation of epistemological and methodological phenomena in science requires a method that is rooted in formal methods, I consider two alternative methods for epistemology of science. One approach is the classical approaches of the syntactic and semantic views of theories. I show that typical approaches of (...)
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  • International Handbook of Research in History, Philosophy and Science Teaching.Michael R. Matthews (ed.) - 2014 - Springer.
    This inaugural handbook documents the distinctive research field that utilizes history and philosophy in investigation of theoretical, curricular and pedagogical issues in the teaching of science and mathematics. It is contributed to by 130 researchers from 30 countries; it provides a logically structured, fully referenced guide to the ways in which science and mathematics education is, informed by the history and philosophy of these disciplines, as well as by the philosophy of education more generally. The first handbook to cover the (...)
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  • Computer Simulations in Science.Eric Winsberg - forthcoming - Stanford Encyclopedia of Philosophy.
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  • Generative Modelling in Physics and in Physics Education: From Aspects of Research Practices to Suggestions for Education.Ismo T. Koponen & Suvi Tala - 2014 - In Michael R. Matthews (ed.), International Handbook of Research in History, Philosophy and Science Teaching. Springer. pp. 1143-1169.
    The extensive use of modelling in physics research has many implications on how it is used in physics education. An interesting case is the use of models in producing of new knowledge, which we here refer to as generative modelling. Generative modelling can serve as a cognitive tool bridging conceptual reality and real phenomena by mutually fitting of simulations and experiments. In this fitting process of fitting, pursuing partial mimetic similarity in simulations and experiments acquires a central epistemological role. At (...)
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  • A priori measurable worlds.Ulrich Krohs - unknown
    Part of the scientific enterprise is to measure the material world and to explain its dynamics by means of models. However, not only is measurability of the world limited, analyzability of models is so, too. Most often, computer simulations offer a way out of this epistemic bottleneck. They instantiate the model and may help to analyze it. In relation to the material world a simulation may be regarded as a kind of a “non-material scale model”. Like any other scale model, (...)
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  • Explaining simulated phenomena. A defense of the epistemic power of computer simulations.Juan M. Durán - 2013 - Dissertation, University of Stuttgart
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  • Degrees of Epistemic Opacity.Iñaki San Pedro - manuscript
    The paper analyses in some depth the distinction by Paul Humphreys between "epistemic opacity" —which I refer to as "weak epistemic opacity" here— and "essential epistemic opacity", and defends the idea that epistemic opacity in general can be made sense as coming in degrees. The idea of degrees of epistemic opacity is then exploited to show, in the context of computer simulations, the tight relation between the concept of epistemic opacity and actual scientific (modelling and simulation) practices. As a consequence, (...)
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  • Tools or toys? On specific challenges for modeling and the epistemology of models and computer simulations in the social sciences.Eckhart Arnold - manuscript
    Mathematical models are a well established tool in most natural sciences. Although models have been neglected by the philosophy of science for a long time, their epistemological status as a link between theory and reality is now fairly well understood. However, regarding the epistemological status of mathematical models in the social sciences, there still exists a considerable unclarity. In my paper I argue that this results from specific challenges that mathematical models and especially computer simulations face in the social sciences. (...)
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  • When can a Computer Simulation act as Substitute for an Experiment? A Case-Study from Chemisty.Johannes Kästner & Eckhart Arnold - manuscript
    In this paper we investigate with a case study from chemistry under what conditions a simulation can serve as a surrogate for an experiment. The case-study concerns a simulation of H2-formation in outer space. We find that in this case the simulation can act as a surrogate for an experiment, because there exists comprehensive theoretical background knowledge in form of quantum mechanics about the range of phenomena to which the investigated process belongs and because any particular modelling assumptions as can (...)
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  • Tools for Evaluating the Consequences of Prior Knowledge, but no Experiments. On the Role of Computer Simulations in Science.Eckhart Arnold - manuscript
    There is an ongoing debate on whether or to what degree computer simulations can be likened to experiments. Many philosophers are sceptical whether a strict separation between the two categories is possible and deny that the materiality of experiments makes a difference (Morrison 2009, Parker 2009, Winsberg 2010). Some also like to describe computer simulations as a “third way” between experimental and theoretical research (Rohrlich 1990, Axelrod 2003, Kueppers/Lenhard 2005). In this article I defend the view that computer simulations are (...)
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