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  1. Preservative realism and its discontents: Revisiting caloric.Hasok Chang - 2003 - Philosophy of Science 70 (5):902-912.
    A popular and plausible response against Laudan's “pessimistic induction” has been what I call “preservative realism,” which argues that there have actually been enough elements of scientific knowledge preserved through major theory‐change processes, and that those elements can be accepted realistically. This paper argues against preservative realism, in particular through a critical review of Psillos's argument concerning the case of the caloric theory of heat. Contrary to his argument, the historical record of the caloric theory reveals that beliefs about the (...)
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  • Consciousness and the Philosophy of Signs: How Peircean Semiotics Combines Phenomenal Qualia and Practical Effects.Marc Champagne - 2018 - Cham: Springer.
    It is often thought that consciousness has a qualitative dimension that cannot be tracked by science. Recently, however, some philosophers have argued that this worry stems not from an elusive feature of the mind, but from the special nature of the concepts used to describe conscious states. Marc Champagne draws on the neglected branch of philosophy of signs or semiotics to develop a new take on this strategy. The term “semiotics” was introduced by John Locke in the modern period – (...)
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  • Looking for structure in all the wrong places: Ramsey sentences, multiple realisability, and structure.Angelo Cei & Steven French - 2006 - Studies in History and Philosophy of Science Part A 37 (4):633-655.
    ‘Epistemic structural realism’ (ESR) insists that all that we know of the world is its structure, and that the ‘nature’ of the underlying elements remains hidden. With structure represented via Ramsey sentences, the question arises as to how ‘hidden natures’ might also be represented. If the Ramsey sentence describes a class of realisers for the relevant theory, one way of answering this question is through the notion of multiple realisability. We explore this answer in the context of the work of (...)
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  • Structural Distinctions: Entities, Structures, and Changes in Science.Angelo Cei - 2005 - Philosophy of Science 72 (5):1385-1396.
    Abstract. I argue that pessimistic meta-induction (PMI) seems to point an ontological priority of the relations over the objects of the scientific theories of the kind suggested by French and Ladyman (French and Ladyman 2003). My strategy will involve a critical examination of epistemic structural realism (ESR) and historical case-study: the prediction of Zeeman’s effect in Lorentz’s theory of electron.
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  • Symmetries and Paraparticles as a Motivation for Structuralism.Adam Caulton & Jeremy Butterfield - 2012 - British Journal for the Philosophy of Science 63 (2):233-285.
    This article develops an analogy proposed by Stachel between general relativity (GR) and quantum mechanics (QM) as regards permutation invariance. Our main idea is to overcome Pooley's criticism of the analogy by appeal to paraparticles. In GR, the equations are (the solution space is) invariant under diffeomorphisms permuting spacetime points. Similarly, in QM the equations are invariant under particle permutations. Stachel argued that this feature—a theory's ‘not caring which point, or particle, is which’—supported a structuralist ontology. Pooley criticizes this analogy: (...)
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  • The Challenge of Scientific Realism to Intelligent Design.Christian Carman - 2022 - European Journal for Philosophy of Religion 14 (4):42-69.
    Intelligent Design (ID) argues for the existence of a designer, postulating it as a theoretical entity of a scientific theory aiming to explain specific characteristics in nature that seems to show design. It is commonly accepted within the Scientific Realism debate, however, that asserting that a scientific theory is successful is not enough for accepting the extramental existence of the entities it postulates. Instead, scientific theories must fulfill additional epistemic requirements, one of which is that they must show successful novel (...)
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  • Did Ptolemy make novel predictions? Launching Ptolemaic astronomy into the scientific realism debate.Christián Carman & José Díez - 2015 - Studies in History and Philosophy of Science Part A 52:20-34.
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  • What structures could not be.Jacob Busch - 2003 - International Studies in the Philosophy of Science 17 (3):211 – 225.
    James Ladyman has recently proposed a view according to which all that exists on the level of microphysics are structures "all the way down". By means of a comparative reading of structuralism in philosophy of mathematics as proposed by Stewart Shapiro, I shall present what I believe structures could not be. I shall argue that, if Ladyman is indeed proposing something as strong as suggested here, then he is committed to solving problems that proponents of structuralism in philosophy of mathematics (...)
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  • The Indispensability Argument for Mathematical Realism and Scientific Realism.Jacob Busch - 2012 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 43 (1):3-9.
    Confirmational holism is central to a traditional formulation of the indispensability argument for mathematical realism (IA). I argue that recent strategies for defending scientific realism are incompatible with confirmational holism. Thus a traditional formulation of IA is incompatible with recent strategies for defending scientific realism. As a consequence a traditional formulation of IA will only have limited appeal.
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  • Scientific Realism and the Indispensability Argument for Mathematical Realism: A Marriage Made in Hell.Jacob Busch - 2011 - International Studies in the Philosophy of Science 25 (4):307-325.
    An emphasis on explanatory contribution is central to a recent formulation of the indispensability argument for mathematical realism. Because scientific realism is argued for by means of inference to the best explanation, it has been further argued that being a scientific realist entails a commitment to IA and thus to mathematical realism. It has, however, gone largely unnoticed that the way that IBE is argued to be truth conducive involves citing successful applications of IBE and tracing this success over time. (...)
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  • Is the Indispensability Argument Dispensable?Jacob Busch - 2011 - Theoria 77 (2):139-158.
    When the indispensability argument for mathematical entities (IA) is spelled out, it would appear confirmational holism is needed for the argument to work. It has been argued that confirmational holism is a dispensable premise in the argument if a construal of naturalism, according to which it is denied that we can take different epistemic attitudes towards different parts of our scientific theories, is adopted. I argue that the suggested variety of naturalism will only appeal to a limited number of philosophers. (...)
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  • A structuralist interpretation of the relational interpretation.Giovanni Buonocore - 2022 - Theoria 88 (4):733-742.
    Theoria, Volume 88, Issue 4, Page 733-742, August 2022.
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  • What is structural empiricism? Scientific change in an empiricist setting.Otávio Bueno - 1999 - Erkenntnis 50 (1):55-81.
    In this paper a constructive empiricist account of scientific change is put forward. Based on da Costa's and French's partial structures approach, two notions of empirical adequacy are initially advanced (with particular emphasis on the introduction of degrees of empirical adequacy). Using these notions, it is shown how both the informativeness and the empirical adequacy requirements of an empiricist theory of scientific change can then be met. Finally, some philosophical consequences with regard to the role of structures in this context (...)
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  • Structural Realism, Scientific Change, and Partial Structures.Otávio Bueno - 2008 - Studia Logica 89 (2):213-235.
    Scientific change has two important dimensions: conceptual change and structural change. In this paper, I argue that the existence of conceptual change brings serious difficulties for scientific realism, and the existence of structural change makes structural realism look quite implausible. I then sketch an alternative account of scientific change, in terms of partial structures, that accommodates both conceptual and structural changes. The proposal, however, is not realist, and supports a structuralist version of van Fraassen’s constructive empiricism (structural empiricism).
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  • Realism and Anti-Realism about Science.Otávio Bueno - 2015 - International Journal for the Study of Skepticism 5 (2):145-167.
    Pyrrhonists provide a way of investigating the world in which conflicting views about a given topic are critically compared, assessed, and juxtaposed. Since Pyrrhonists are ultimately unable to decide between these views, they end up suspending judgment about the issues under examination. In this paper, I consider the question of whether Pyrrhonists can be realists or anti-realists about science, focusing, in particular, on contemporary philosophical discussions about it. Althoughprima faciethe answer seems to be negative, I argue that if realism and (...)
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  • Empiricism, scientific change and mathematical change.Otávio Bueno - 2000 - Studies in History and Philosophy of Science Part A 31 (2):269-296.
    The aim of this paper is to provide a unified account of scientific and mathematical change in a thoroughly empiricist setting. After providing a formal modelling in terms of embedding, and criticising it for being too restrictive, a second modelling is advanced. It generalises the first, providing a more open-ended pattern of theory development, and is articulated in terms of da Costa and French's partial structures approach. The crucial component of scientific and mathematical change is spelled out in terms of (...)
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  • Dispensing with Facts, Substances, and Structures.Otávio Bueno - 2023 - American Philosophical Quarterly 60 (1):49-61.
    Despite the alleged roles played by structures, substances, and facts in mathematical and metaphysical theorizing, in this paper I provide a strategy to dispense with them. It is argued that one need not be committed to the existence of these posits nor with the metaphysically inflationary interpretations that support them. An alternative, deflationary approach is then sketched.
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  • Intellectualizing Medicine: A Reply to Commentaries on “Prediction, Understanding, and Medicine”.Alex Broadbent - 2018 - Journal of Medicine and Philosophy 43 (3):325-341.
    This article is a reply to two critics of my “Prediction, Understanding, and Medicine,” published elsewhere in this journal issue. In that essay, I argued that medicine is best understood not as essentially a curative enterprise, but rather as one essentially oriented towards prediction and understanding. Here, I defend this position from several criticisms made of it.
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  • Functionalism and The Independence Problems.Darren Bradley - 2013 - Noûs 47 (1):545-557.
    The independence problems for functionalism stem from the worry that if functional properties are defined in terms of their causes and effects then such functional properties seem to be too intimately connected to these purported causes and effects. I distinguish three different ways the independence problems can be filled out – in terms of necessary connections, analytic connections and vacuous explanations. I argue that none of these present serious problems. Instead, they bring out some important and over-looked features of functionalism.
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  • Ventajas y tensiones en la perspectiva del Estructuralismo Empirista.Bruno Borge & Susana Lucero - 2018 - Revista de Filosofía 43 (2):315-338.
    En el presente trabajo analizamos críticamente el modo en que el Estructuralismo Empirista de van Fraassen caracteriza la relación de representación entre las teorías y los fenómenos. Nuestro objetivo es ofrecer argumentos que destaquen el papel del objeto en la construcción de modelos de datos. Asimismo, nos proponemos mostrar que la opción metodológica sugerida en su obra reciente resulta insuficiente para recuperar un vínculo plausible entre los modelos de datos y los fenómenos.
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  • Hacia una ontología sin objetos: una defensa del realismo estructural óntico en el nivel metodológico.Bruno José Borge - 2013 - Filosofia Unisinos 14 (1).
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  • Epistemic structural realism, modality and laws of nature.Bruno Borge - 2018 - Theoria: Revista de Teoría, Historia y Fundamentos de la Ciencia 33 (3):447-468.
    According to epistemic structural realism scientific theories provide us only with knowledge about the structure of the unobservable world, but not about its nature. The most significant objection that this posi- tion has faced is the so-called Newman’s problem. In this paper I offer an alternative objection to EER. I argue that its formulation leads to undesirable skeptical positions in two fields close to scientific realism: the debates on modality and laws of nature. I also show that there is an (...)
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  • Two Styles of Reasoning in Scientific Practices: Experimental and Mathematical Traditions.Mieke Boon - 2011 - International Studies in the Philosophy of Science 25 (3):255 - 278.
    This article outlines a philosophy of science in practice that focuses on the engineering sciences. A methodological issue is that these practices seem to be divided by two different styles of scientific reasoning, namely, causal-mechanistic and mathematical reasoning. These styles are philosophically characterized by what Kuhn called ?disciplinary matrices?. Due to distinct metaphysical background pictures and/or distinct ideas of what counts as intelligible, they entail distinct ideas of the character of phenomena and what counts as a scientific explanation. It is (...)
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  • Realism versus anti-realism: philosophical problem or scientific concern?Jesús P. Zamora Bonilla - 2019 - Synthese 196 (10):3961-3977.
    The decision whether to have a realist or an anti-realist attitude towards scientific hypotheses is interpreted in this paper as a choice that scientists themselves have to face in their work as scientists, rather than as a ‘philosophical’ problem. Scientists’ choices between realism and instrumentalism are interpreted in this paper with the help of two different conceptual tools: a deflationary semantics grounded in the inferentialist approach to linguistic practices developed by some authors, and an epistemic utility function that tries to (...)
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  • The Positive Argument Against Scientific Realism.Florian J. Boge - 2023 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 54 (4):535-566.
    Putnam coined what is now known as the no miracles argument “[t]he positive argument for realism”. In its opposition, he put an argument that by his own standards counts as negative. But are there no positive arguments against scientific realism? I believe that there is such an argument that has figured in the back of much of the realism-debate, but, to my knowledge, has nowhere been stated and defended explicitly. This is an argument from the success of quantum physics to (...)
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  • Quantum reality: A pragmaticized neo-Kantian approach.Florian J. Boge - 2021 - Studies in History and Philosophy of Science Part A 87 (C):101-113.
    Despite remarkable efforts, it remains notoriously difficult to equip quantum theory with a coherent ontology. Hence, Healey (2017, 12) has recently suggested that ‘‘quantum theory has no physical ontology and states no facts about physical objects or events’’, and Fuchs et al. (2014, 752) similarly hold that ‘‘quantum mechanics itself does not deal directly with the objective world’’. While intriguing, these positions either raise the question of how talk of ‘physical reality’ can even remain meaningful, or they must ultimately embrace (...)
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  • Incompatibility and the pessimistic induction: a challenge for selective realism.Florian J. Boge - 2021 - European Journal for Philosophy of Science 11 (2):1-31.
    Two powerful arguments have famously dominated the realism debate in philosophy of science: The No Miracles Argument (NMA) and the Pessimistic Meta-Induction (PMI). A standard response to the PMI is selective scientific realism (SSR), wherein only the working posits of a theory are considered worthy of doxastic commitment. Building on the recent debate over the NMA and the connections between the NMA and the PMI, I here consider a stronger inductive argument that poses a direct challenge for SSR: Because it (...)
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  • The rationale behind Pierre Duhem's natural classification.Sindhuja Bhakthavatsalam - 2015 - Studies in History and Philosophy of Science Part A 51:11-21.
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  • Meta-Incommensurability between Theories of Meaning: Chemical Evidence.Nicholas W. Best - 2015 - Perspectives on Science 23 (3):361-378.
    Attempting to compare scientific theories requires a philosophical model of meaning. Yet different scientific theories have at times—particularly in early chemistry—pre-supposed disparate theories of meaning. When two theories of meaning are incommensurable, we must say that the scientific theories that rely upon them are meta-incommensurable. Meta- incommensurability is a more profound sceptical threat to science since, unlike first-order incommensurability, it implies complete incomparability.
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  • The world is either digital or analogue.Francesco Berto & Jacopo Tagliabue - 2014 - Synthese 191 (3):481-497.
    We address an argument by Floridi (Synthese 168(1):151–178, 2009; 2011a), to the effect that digital and analogue are not features of reality, only of modes of presentation of reality. One can therefore have an informational ontology, like Floridi’s Informational Structural Realism, without commitment to a supposedly digital or analogue world. After introducing the topic in Sect. 1, in Sect. 2 we explain what the proposition expressed by the title of our paper means. In Sect. 3, we describe Floridi’s argument. In (...)
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  • The Downward Path to Epistemic Informational Structural Realism.Majid Davoody Beni - 2018 - Acta Analytica 33 (2):181-197.
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  • The Benacerraf Problem as a Challenge for Ontic Structural Realism.Majid Davoody Beni - 2020 - Philosophia Mathematica 28 (1):35-59.
    Benacerraf has presented two problems for the philosophy of mathematics. These are the problem of identification and the problem of representation. This paper aims to reconstruct the latter problem and to unpack its undermining bearing on the version of Ontic Structural Realism that frames scientific representations in terms of abstract structures. I argue that the dichotomy between mathematical structures and physical ones cannot be used to address the Benacerraf problem but strengthens it. I conclude by arguing that versions of OSR (...)
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  • Structural Realism, Metaphysical Unification, and the Ontology and Epistemology of Patterns.Majid Davoody Beni - 2017 - International Studies in the Philosophy of Science 31 (3):285-300.
    ABSTRACTLadyman and Ross’s account of the metaphysical component of ontic structural realism was associated with a unificationist view of the connection between fundamental physics and special sciences. The aim of the present article is to assess the sense of unification that is at issue in Ladyman and Ross’s definition of metaphysics. Given the ontic core of Ladyman and Ross’s version of structural realism, it should be assumed that the unifying endeavour is worthwhile only if the connective links that underpin unification (...)
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  • Selective Realism and the Framework/Interaction Distinction: A Taxonomy of Fundamental Physical Theories.Federico Benitez - 2019 - Foundations of Physics 49 (7):700-716.
    Following the proposal of a new kind of selective structural realism that uses as a basis the distinction between framework and interaction theories, this work discusses relevant applications in fundamental physics. An ontology for the different entities and properties of well-known theories is thus consistently built. The case of classical field theories—including general relativity as a classical theory of gravitation—is examined in detail, as well as the implications of the classification scheme for issues of realism in quantum mechanics. These applications (...)
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  • Structural realism and theory classification.Federico Benitez - 2023 - Theoria 89 (5):734-747.
    Ontic structural realism constitutes a promising take on scientific realism, one that avoids the well‐known issues that realist stances have with underdetermination and theory change. In its most radical versions, ontic structural realism proposes a type of eliminativism about theoretical entities, ascribing ontological commitment only to the structures, and not to the objects appearing in our theories. More moderate versions of ontic structural realism have also been proposed, allowing for ‘thin’ objects in the ontology. This work connects these takes on (...)
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  • Structural Realism About the Free Energy Principle, the Best of Both Worlds.Majid D. Beni - forthcoming - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie:1-15.
    There are realist and antirealist interpretations of the free energy principle (FEP). This paper aims to chart out a structural realist interpretation of FEP. To do so, it draws on Worrall’s (Dialectica 43(1–2): 99–124, 1989) proposal. The general insight of Worrall’s paper is that there is progress at the level of the structure of theories rather than their content. To enact Worrall’s strategy in the context of FEP, this paper will focus on characterising the formal continuity between fundamental equations of (...)
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  • Structures in Physics and Neuroscience.Majid Davoody Beni & Georg Northoff - 2021 - Axiomathes 31 (4):479-495.
    We offer to extend structural realism into the field of mind and brain studies. The naturalised metaphysics of structural realism has been defined in terms of unification of sciences. The unification program has been carried out nicely in fields of Quantum Mechanics and General Relativity. But for the structural realist metaphysics to receive a recommendation, the unification program needs to be extended to the fields of especial sciences. Our aim in the paper is twofold. On the one hand, we present (...)
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  • Syntactical Informational Structural Realism.Majid Davoody Beni - 2018 - Minds and Machines 28 (4):623-643.
    Luciano Floridi’s informational structural realism takes a constructionist attitude towards the problems of epistemology and metaphysics, but the question of the nature of the semantical component of his view remains vexing. In this paper, I propose to dispense with the semantical component of ISR completely. I outline a Syntactical version of ISR. The unified entropy-based framework of information has been adopted as the groundwork of SISR. To establish its realist component, SISR should be able to dissolve the latching problem. We (...)
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  • Reconstructing the upward path to structural realism.Majid Davoody Beni - 2017 - European Journal for Philosophy of Science 7 (3):393-409.
    In his Analysis of Matter, Russell advocated an epistemic form of Epistemic Structural Realism which held that our knowledge of the external world is structural. This approach has been criticised by M.H.A. Newman, 137–148, 1928) and Stathis Psillos, S13–S24, 2001). The paper aims to reconstruct Russell’s version of ESR, and defend its experimental and philosophical plausibility. The basic assumption is that without getting a viable experimental handle on the linkage between the structure of perceptions and causal structure of the stimuli, (...)
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  • Reconstructing Probabilistic Realism: Re-enacting Syntactical Structures.Majid Davoody Beni - 2020 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 51 (2):293-313.
    Probabilistic realism and syntactical positivism were two among outdated theories that Feigl criticised on account of their semantical poverty. In this paper, I argue that a refined version of probabilistic realism, which relies on what Feigl specified as the pragmatic description of the symbolic behaviour of scientists’ estimations and foresight, is defendable. This version of statistical realism does not need to make the plausibility of realist thesis dependent on the conventional acceptance of a constructed semantic metalanguage. I shall rely on (...)
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  • On the Thinking Brains and Tinkering with the Scientific Models.Majid Davoody Beni - 2018 - Axiomathes 28 (1):37-51.
    The paper aims to provide a detailed assessment of Tim Crane’s recent invocation of the notion of scientific models in the way of dealing with the issue of the brain’s representational states. In this paper, I assess Crane’s proposal under a charitable and a less charitable reading. I argue that Crane’s use of scientific models is at best compatible with his expression of psychological realism. However, Crane’s use of model-based strategy by no means underlay, support, or strengthen his psychological realism. (...)
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  • Much Ado About Nothing: Toward a Structural Realist Theory of Intentionality.Majid Davoody Beni - 2018 - Axiomathes 28 (3):293-308.
    Building upon Brentano’s Psychology from an empirical standpoint. Routledge, London, [1874] Brentano 1995) reintroduction of the concept of intentionality to the contemporary philosophy, Tim Crane has famously presented the intentionality as the mark of the mental. Accordingly, the problem of “intentional existence” has resurfaced in Crane’s revival of the Brentanoian theme. Here, I revise Crane’s construal of Brentano’s notion of intentional inexistence and reinterpret it in terms of a moderate version of relationalism. My relationalist theory of intentionality is inspired by (...)
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  • Causal Informational Structural Realism.Majid D. Beni - 2020 - International Studies in the Philosophy of Science 33 (2):117-134.
    ABSTRACT The debate between proponents and opponents of causal foundationalism has recently surfaced as a disparity between causal structuralism and causal anti-foundationalism in the structural realist camp. The paper outlines and dissolves the problem of disparity for structural realism. I follow John Collier to specify causation in terms of the transmission of information. Unlike them, I built upon the reverse quantum data-processing inequality to show how this approach models causation as a symmetric process at the level of fundamental physics. I (...)
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  • An outline of a unified theory of the relational self: grounding the self in the manifold of interpersonal relations.Majid Davoody Beni - 2019 - Phenomenology and the Cognitive Sciences 18 (3):473-491.
    The paper outlines a structuralist unification between two existing relational theories of the self, i.e., Beni's Structural Realist theory of the Self and Gallese's Embodied Relational Self. Each one of these theories provides a structuralist account of some aspects of the self but leaves out some other aspects which are indispensable to a comprehensive account of the self. SRS accounts for the reflective aspects of the self, and ERS accounts for the environmental and social aspects of the self. In this (...)
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  • An Empiricist Criterion of Meaning.Yann Benétreau-Dupin - 2011 - South African Journal of Philosophy 30 (2):95-108.
    The meaning of scientific propositions is not always expressible in terms of observable phenomena. Such propositions involve generalizations, and also terms that are theoretical constructs. I study here how to assess the meaning of scientific propositions, that is, the specific import of theoretical terms. Empiricists have expressed a concern that scientific propositions, and theoretical terms, should always be, to some degree, related to observable consequences. We can see that the former empiricist criterion of meaning only implies for theoretical terms not (...)
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  • A critical analysis of Markovian monism.Majid D. Beni - 2021 - Synthese 199 (3-4):6407-6427.
    Free Energy Principle underlies a unifying framework that integrates theories of origins of life, cognition, and action. Recently, FEP has been developed into a Markovian monist perspective. The paper expresses scepticism about the validity of arguments for Markovian monism. The critique is based on the assumption that Markovian models are scientific models, and while we may defend ontological theories about the nature of scientific models, we could not read off metaphysical theses about the nature of target systems from our theories (...)
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  • Underdetermination, Realism, and Theory Appraisal: An Epistemological Reflection on Quantum Mechanics.Darrin W. Belousek - 2005 - Foundations of Physics 35 (4):669-695.
    This paper examines the epistemological significance of the present situation of underdetermination in quantum mechanics. After analyzing this underdetermination at three levels---formal, ontological, and methodological---the paper considers implications for a number of variants of the thesis of scientific realism in fundamental physics and reassesses Lakatos‘ characterization of progress in physical theory in light of the present situation. Next, this paper considers the implications of underdetermination for Weinberg’s ‘‘dream of a final theory.’’ Finally, the paper concludes by suggesting how one might (...)
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  • Scientific Theories and Philosophical Stances: Themes from van Fraassen.Claus Beisbart & Michael Frauchiger (eds.) - 2024 - De Gruyter.
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  • Scientific Realism in the Wild: An Empirical Study of Seven Sciences and History and Philosophy of Science.James R. Beebe & Finnur Dellsén - 2020 - Philosophy of Science 87 (2):336-364.
    We report the results of a study that investigated the views of researchers working in seven scientific disciplines and in history and philosophy of science in regard to four hypothesized dimensions of scientific realism. Among other things, we found that natural scientists tended to express more strongly realist views than social scientists, that history and philosophy of science scholars tended to express more antirealist views than natural scientists, that van Fraassen’s characterization of scientific realism failed to cluster with more standard (...)
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  • The manipulability of what? The history of G-protein coupled receptors.Ann-Sophie Barwich & Karim Bschir - 2017 - Biology and Philosophy 32 (6):1317-1339.
    This paper tells the story of G-protein coupled receptors, one of the most important scientific objects in contemporary biochemistry and molecular biology. By looking at how cell membrane receptors turned from a speculative concept into a central element in modern biochemistry over the past 40 years, we revisit the role of manipulability as a criterion for entity realism in wet-lab research. The central argument is that manipulability as a condition for reality becomes meaningful only once scientists have decided how to (...)
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