Going back at least to Duhem, there is a tradition of thinking that crucial experiments are impossible in science. I analyse Duhem's arguments and show that they are based on the excessively strong assumption that only deductive reasoning is permissible in experimental science. This opens the possibility that some principle of inductive inference could provide a sufficient reason for preferring one among a group of hypotheses on the basis of an appropriately controlled experiment. To be sure, there are analogues to (...) Duhem's problems that pertain to inductive inference. Using a famous experiment from the history of molecular biology as an example, I show that an experimentalist version of inference to the best explanation (IBE) does a better job in handling these problems than other accounts of scientific inference. Furthermore, I introduce a concept of experimental mechanism and show that it can guide inferences from data within an IBE-based framework for induction. 1. Introduction2. Duhem on the Logic of Crucial Experiments3. ‘The Most Beautiful Experiment in Biology’4. Why Not Simple Elimination?5. Severe Testing6. An Experimentalist Version of IBE 6.1. Physiological and experimental mechanisms6.2. Explaining the data6.3. IBE and the problem of untested auxiliaries6.4. IBE-turtles all the way down7. Van Fraassen's ‘Bad Lot’ Argument8. IBE and Bayesianism9. Conclusions. (shrink)

The detailed analysis of a particular quasi-historical numerical example is used to illustrate the way in which a Bayesian personalist approach to scientific inference resolves the Duhemian problem of which of a conjunction of hypotheses to reject when they jointly yield a prediction which is refuted. Numbers intended to be approximately historically accurate for my example show, in agreement with the views of Lakatos, that a refutation need have astonishingly little effect on a scientist's confidence in the ‘hard core’ of (...) a successful research programme even when a comparable confirmation would greatly enhance that confidence. Timeo Danaos et dona ferentis. (shrink)

In what follows I will discuss an example of the Duhem-Quine problem in which Pr(H A), Pr(A H), and Pr(OI +H& ?A) (where H is the hypothesis, A the auxiliary assumptions, and O the observational prediction) can be construed objectively; however, only some of those quantities are relevant to the analysis that I provide. The example involves medical diagnosis. The goal is to test the hypothesis that someone has tuberculosis; the auxiliary assumptions describe the er- ror characteristics of the test (...) procedure. Although it can make sense to talk about the objective probability that someone (randomly drawn from a given population) has tuberculosis and it also can make sense to talk about the objective probability that a test procedure has a certain set of error characteristics, neither of these quantities will enter into the analysis. The analysis proceeds entirely via likelihoods, what one needs to consider is just the probability of the observations conditional on four conjunctions of the form (?H & +A).' It is a special feature of the example that all four of these conjunctions are simple statistical hypotheses in the technical sense that each unambigu-ously confers a probability on the observations.'o After describing how the likelihood concept applies to the example concerning medical diagnosis, I will show how similar patterns can arise in the context of a second inferential framework-that of H. Akaike's criterion of model selection;" this time the example will involve phylogenetic inference. (shrink)

Duhem’s concept of “good sense” is central to his philosophy of science, given that it is what allows scientist to decide between competing theories. Scientists must use good sense and have intellectual and moral virtues in order to be neutral arbiters of scientific theories, especially when choosing between empirically adequate theories. I discuss the parallels in Duhem’s views to those of virtue epistemologists, who understand justified belief as that arrived at by a cognitive agent with intellectual and moral virtues, showing (...) how consideration of Duhem as a virtue epistemologist offers insights into his views, as well as providing possible answers to some puzzles about virtue epistemology. The extent to which Duhem holds that the intellectual and moral virtues of the scientist determine scientific knowledge has not been generally noticed. (shrink)

There has been a significant interest in the recent literature in developing a solution to the problem of theory choice which is both normative and descriptive, but agent-based rather than rule-based, originating from Pierre Duhem’s notion of ‘good sense’. In this paper we present the properties Duhem attributes to good sense in different contexts, before examining its current reconstructions advanced in the literature and their limitations. We propose an alternative account of good sense, seen as promoting social consensus in science, (...) and show that it is superior to its rivals in two respects: it is more faithful to Duhemian good sense, and it cashes out the effect that virtues have on scientific progress. We then defend the social consensus account against objections that highlight the positive role of diversity and division of labour in science. (shrink)

Scientific reasoning is—and ought to be—conducted in accordance with the axioms of probability. This Bayesian view—so called because of the central role it accords to a theorem first proved by Thomas Bayes in the late eighteenth ...

This innovative book focuses on the development of the gene theory as a case study in scientific creativity.

This paper examines the standard Bayesian solution to the Quine–Duhem problem, the problem of distributing blame between a theory and its auxiliary hypotheses in the aftermath of a failed prediction. The standard solution, I argue, begs the question against those who claim that the problem has no solution. I then provide an alternative Bayesian solution that is not question-begging and that turns out to have some interesting and desirable properties not possessed by the standard solution. This solution opens the way (...) to a satisfying treatment of a problem concerning ad hoc auxiliary hypotheses. (shrink)

has proposed an interesting and novel Bayesian analysis of the Quine-Duhem (Q–D) problem (i.e., the problem of auxiliary hypotheses). Strevens's analysis involves the use of a simplifying idealization concerning the original Q–D problem. We will show that this idealization is far stronger than it might appear. Indeed, we argue that Strevens's idealization oversimplifies the Q–D problem, and we propose a diagnosis of the source(s) of the oversimplification. Some background on Quine–Duhem Strevens's simplifying idealization Indications that (I) oversimplifies Q–D Strevens's argument (...) for the legitimacy of (I). (shrink)

I argue that the Bayesian Way of reconstructing Duhem's problem fails to advance a solution to the problem of which of a group of hypotheses ought to be rejected or "blamed" when experiment disagrees with prediction. But scientists do regularly tackle and often enough solve Duhemian problems. When they do, they employ a logic and methodology which may be called error statistics. I discuss the key properties of this approach which enable it to split off the task of testing auxiliary (...) hypotheses from that of appraising a primary hypothesis. By discriminating patterns of error, this approach can at least block, if not also severely test, attempted explanations of an anomaly. I illustrate how this approach directs progress with Duhemian problems and explains how scientists actually grapple with them. (shrink)

This paper examines Duhem’s concept of good sense as an attempt to support a non rule-governed account of rationality in theory choice. Faced with the underdetermination of theory by evidence thesis and the continuity thesis, Duhem tried to account for the ability of scientists to choose theories that continuously grow to a natural classification. I will examine the concept of good sense and the problems that stem from it. I will also present a recent attempt by David Stump to link (...) good sense to virtue epistemology. I will argue that even though this approach can be useful for the better comprehension of the concept of good sense, there are some substantial differences between virtue epistemologists and Duhem. In the light of this reconstruction of good sense, I will propose a possible way to interpret the concept of good sense, which overcomes the noted problems and fits better with Duhem’s views on scientific method and motivation in developing the concept of good sense. (shrink)