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  1. Reductionism and its heuristics: Making methodological reductionism honest.William C. Wimsatt - 2006 - Synthese 151 (3):445-475.
    Methodological reductionists practice ‘wannabe reductionism’. They claim that one should pursue reductionism, but never propose how. I integrate two strains in prior work to do so. Three kinds of activities are pursued as “reductionist”. “Successional reduction” and inter-level mechanistic explanation are legitimate and powerful strategies. Eliminativism is generally ill-conceived. Specific problem-solving heuristics for constructing inter-level mechanistic explanations show why and when they can provide powerful and fruitful tools and insights, but sometimes lead to erroneous results. I show how traditional metaphysical (...)
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  • What is Proof of Concept Research and how does it Generate Epistemic and Ethical Categories for Future Scientific Practice?Catherine Elizabeth Kendig - 2016 - Science and Engineering Ethics 22 (3):735-753.
    “Proof of concept” is a phrase frequently used in descriptions of research sought in program announcements, in experimental studies, and in the marketing of new technologies. It is often coupled with either a short definition or none at all, its meaning assumed to be fully understood. This is problematic. As a phrase with potential implications for research and technology, its assumed meaning requires some analysis to avoid it becoming a descriptive category that refers to all things scientifically exciting. I provide (...)
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  • Multiple Realizability Revisited: Linking Cognitive and Neural States.William Bechtel - 1999 - Philosophy of Science 66 (2):175-207.
    The claim of the multiple realizability of mental states by brain states has been a major feature of the dominant philosophy of mind of the late 20th century. The claim is usually motivated by evidence that mental states are multiply realized, both within humans and between humans and other species. We challenge this contention by focusing on how neuroscientists differentiate brain areas. The fact that they rely centrally on psychological measures in mapping the brain and do so in a comparative (...)
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  • The Functional Unity of Special Science Kinds.Daniel A. Weiskopf - 2011 - British Journal for the Philosophy of Science 62 (2):233-258.
    The view that special science properties are multiply realizable has been attacked in recent years by Shapiro, Bechtel and Mundale, Polger, and others. Focusing on psychological and neuroscientific properties, I argue that these attacks are unsuccessful. By drawing on interspecies physiological comparisons I show that diverse physical mechanisms can converge on common functional properties at multiple levels. This is illustrated with examples from the psychophysics and neuroscience of early vision. This convergence is compatible with the existence of general constraints on (...)
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  • How to test for multiple realization.Lawrence A. Shapiro - 2008 - Philosophy of Science 75 (5):514-525.
    When conceived as an empirical claim, it is natural to wonder how one might test the hypothesis of multiple realization. I consider general issues of testability, show how they apply specifically to the hypothesis of multiple realization, and propose an auxiliary assumption that, I argue, must be conjoined to the hypothesis of multiple realization to ensure its testability. I argue further that Bechtel and Mundale go astray because they fail to appreciate the need for this auxiliary assumption. †To contact the (...)
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  • (1 other version)On Multiple Realization and the Special Sciences.Alex Rosenberg - 2001 - Journal of Philosophy 98 (7):365.
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  • Autonomy and multiple realization.Robert C. Richardson - 2008 - Philosophy of Science 75 (5):526-536.
    Multiple realization historically mandated the autonomy of psychology, and its principled irreducibility to neuroscience. Recently, multiple realization and its implications for the reducibility of psychology to neuroscience have been challenged. One challenge concerns the proper understanding of reduction. Another concerns whether multiple realization is as pervasive as is alleged. I focus on the latter question. I illustrate multiple realization with actual, rather than hypothetical, cases of multiple realization from within the biological sciences. Though they do support a degree of autonomy (...)
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  • Synthetic Biology: A Bridge Between Functional and Evolutionary Biology.Michel Morange - 2009 - Biological Theory 4 (4):368-377.
    The interests of synthetic biologists may appear to differ greatly from those of evolutionary biologists. The engineering of organisms must be distinguished from the tinkering action of evolution; the ambition of synthetic biologists is to overcome the limits of natural evolution. But the relations between synthetic biology and evolutionary biology are more complex than this abrupt opposition: Synthetic biology may play an important role in the increasing interactions between functional and evolutionary biology. In practice, synthetic biologists have learnt to submit (...)
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  • Evaluating the evidence for multiple realization.Thomas W. Polger - 2009 - Synthese 167 (3):457 - 472.
    Consider what the brain-state theorist has to do to make good his claims. He has to specify a physical–chemical state such that any organism (not just a mammal) is in pain if and only if (a) it possesses a brain of suitable physical–chemical structure; and (b) its brain is in that physical–chemical state. This means that the physical–chemical state in question must be a possible state of a mammalian brain, a reptilian brain, a mollusc’s brain (octopuses are mollusca, and certainly (...)
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  • Molecular biology and the unity of science.Harold Kincaid - 1990 - Philosophy of Science 57 (4):575-593.
    Advances in molecular biology have generally been taken to support the claim that biology is reducible to chemistry. I argue against that claim by looking in detail at a number of central results from molecular biology and showing that none of them supports reduction because (1) their basic predicates have multiple realizations, (2) their chemical realization is context-sensitive and (3) their explanations often presuppose biological facts rather than eliminate them. I then consider the heuristic and confirmational implications of irreducibility and (...)
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  • Shocking lessons from electric fish: The theory and practice of multiple realization.Brian L. Keeley - 2000 - Philosophy of Science 67 (3):444-465.
    This paper explores the relationship between psychology and neurobiology in the context of cognitive science. Are the sciences that constitute cognitive science independent and theoretically autonomous, or is there a necessary interaction between them? I explore Fodor's Multiple Realization Thesis (MRT) which starts with the fact of multiple realization and purports to derive the theoretical autonomy of special sciences (such as psychology) from structural sciences (such as neurobiology). After laying out the MRT, it is shown that, on closer inspection, the (...)
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  • Multiple realizations.Lawrence A. Shapiro - 2000 - Journal of Philosophy 97 (12):635-654.
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  • Multiple Realizability and Biological Laws.Jani P. Raerinne & Markus I. Eronen - 2012 - History and Philosophy of the Life Sciences 34 (4):521-537.
    We critically analyze Alexander Rosenberg’s argument based on the multiple realizability of biological properties that there are no biological laws. The argument is intuitive and suggestive. Nevertheless, a closer analysis reveals that the argument rests on dubious assumptions about the nature of natural selection, laws of nature, and multiple realizability. We also argue that the argument is limited in scope, since it applies to an outmoded account of laws and the applicability of the argument to other more promising accounts of (...)
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