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  1. The Constitution of Selves.Christopher Williams & Marya Schechtman - 1998 - Philosophical Review 107 (4):641.
    Can we understand what makes someone the same person without understanding what it is to be a person? Prereflectively we might not think so, but philosophers often accord these questions separate treatments, with personal-identity theorists claiming the first question and free-will theorists the second. Yet much of what is of interest to a person—the possibility of survival over time, compensation for past hardships, concern for future projects, or moral responsibility—is not obviously intelligible from the perspective of either question alone. Marya (...)
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  • Are There Moral Differences Between Maternal Spindle Transfer and Pronuclear Transfer?César Palacios-González - 2017 - Medicine, Health Care and Philosophy 20 (4):503-511.
    This paper examines whether there are moral differences between the mitochondrial replacement techniques that have been recently developed in order to help women afflicted by mitochondrial DNA diseases to have genetically related children absent such conditions: maternal spindle transfer and pronuclear transfer. Firstly, it examines whether there is a moral difference between MST and PNT in terms of the divide between somatic interventions and germline interventions. Secondly, it considers whether PNT and MST are morally distinct under a therapy/creation optic. Finally, (...)
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  • The Ethical Challenges of the Clinical Introduction of Mitochondrial Replacement Techniques.John B. Appleby - 2015 - Medicine, Health Care and Philosophy 18 (4):501-514.
    Mitochondrial DNA (mtDNA) diseases are a group of neuromuscular diseases that often cause suffering and premature death. New mitochondrial replacement techniques (MRTs) may offer women with mtDNA diseases the opportunity to have healthy offspring to whom they are genetically related. MRTs will likely be ready to license for clinical use in the near future and a discussion of the ethics of the clinical introduction ofMRTs is needed. This paper begins by evaluating three concerns about the safety of MRTs for clinical (...)
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  • The Metaphysics of Identity.Andr Gallois - 2016 - Routledge.
    The philosophical problem of identity and the related problem of change go back to the ancient Greek philosophers and fascinated later figures including Leibniz, Locke, and Hume. Heraclitus argued that one could not swim in the same river twice because new waters were ever flowing in. When is a river not the same river? If one removes one plank at a time when is a ship no longer a ship? What is the basic nature of identity and persistence? In this (...)
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  • The Organism View Defended.S. Matthew Liao - 2006 - The Monist 89 (3):334-350.
    What are you and I essentially? When do you and I come into and go out of existence? A common response is that we are essentially organisms, that is, we come into existence as organisms and go out of existence when we cease to be organisms. Jeff McMahan has put forward two arguments against the Organism View: the case of dicephalus and a special case of hemispheric commissurotomy. In this paper, I defend the Organism View against these two cases. Because (...)
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  • Twinning, Inorganic Replacement, and the Organism View.S. Matthew Liao - 2010 - Ratio 23 (1):59-72.
    In explicating his version of the Organism View, Eric Olson argues that you begin to exist only after twinning is no longer possible and that you cannot survive a process of inorganic replacement. Assuming the correctness of the Organism View, but pace Olson, I argue in this paper that the Organism View does not require that you believe either proposition. The claim I shall make about twinning helps to advance a debate that currently divides defenders of the Organism View, while (...)
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  • Can There Be Spatially Coincident Entities of the Same Kind?David B. Hershenov - 2003 - Canadian Journal of Philosophy 33 (1):1-22.
    The majority of philosophers believe that the existence of spatially coincident entities is not only a coherent idea but that there are millions of such entities. What such philosophers do not countenance are spatially coincident entities of the same kind. We will call this ‘Locke’s.
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  • Creation Ethics: Reproduction, Genetics and Quality of Life.David DeGrazia - 2015 - Journal of Medical Ethics 41 (5):415-416.
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  • The Mitochondrial Replacement ‘Therapy’ Myth.Tina Rulli - 2017 - Bioethics 31 (4):368-374.
    This article argues that two forms of mitochondrial replacement therapy, maternal spindle transfer and pro-nuclear transfer, are not therapies at all because they do not treat children who are coming into existence. Rather, these technologies merely create healthy children where none was inevitable. Even if creating healthy lives has some value, it is not to be confused with the medical value of a cure or therapy. The article addresses a recent Bioethics article, ‘Mitochondrial Replacement: Ethics and Identity,’ by Wrigley, Wilkinson, (...)
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  • Do Mitochondrial Replacement Techniques Affect Qualitative or Numerical Identity?S. Matthew Liao - 2017 - Bioethics 31 (1):20-26.
    Mitochondrial replacement techniques, known in the popular media as 'three-parent' or 'three-person' IVFs, have the potential to enable women with mitochondrial diseases to have children who are genetically related to them but without such diseases. In the debate regarding whether MRTs should be made available, an issue that has garnered considerable attention is whether MRTs affect the characteristics of an existing individual or whether they result in the creation of a new individual, given that MRTs involve the genetic manipulation of (...)
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  • Mitochondrial Replacement: Ethics and Identity.Anthony Wrigley, Stephen Wilkinson & John B. Appleby - 2015 - Bioethics 29 (9):631-638.
    Mitochondrial replacement techniques have the potential to allow prospective parents who are at risk of passing on debilitating or even life-threatening mitochondrial disorders to have healthy children to whom they are genetically related. Ethical concerns have however been raised about these techniques. This article focuses on one aspect of the ethical debate, the question of whether there is any moral difference between the two types of MRT proposed: Pronuclear Transfer and Maternal Spindle Transfer. It examines how questions of identity impact (...)
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  • Survival and Identity.David K. Lewis - 1976 - In Amelie Oksenberg Rorty (ed.), The Identities of Persons. University of California Press. pp. 17-40.
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  • Personal Identity.Derek Parfit - 1971 - Philosophical Review 80 (January):3-27.
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  • Ethics of Modifying the Mitochondrial Genome.A. L. Bredenoord, W. Dondorp, G. Pennings & G. De Wert - 2011 - Journal of Medical Ethics 37 (2):97-100.
    Recent preclinical studies have shown the feasibility of specific variants of nuclear transfer to prevent mitochondrial DNA disorders. Nuclear transfer could be a valuable reproductive option for carriers of mitochondrial mutations. A clinical application of nuclear transfer, however, would entail germ-line modification, more specifically a germ-line modification of the mitochondrial genome. One of the most prominent objections against germ-line modification is the fear that it would become possible to alter ‘essential characteristics’ of a future person, thereby possibly violating the child's (...)
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  • Reasons and Persons.Joseph Margolis - 1986 - Philosophy and Phenomenological Research 47 (2):311-327.
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  • Self-Knowledge and Self-Identity.Henry W. Johnstone - 1964 - Philosophy and Phenomenological Research 25 (1):137-138.
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  • Identity and Spatio-Temporal Continuity.John Perry - 1970 - Journal of Symbolic Logic 35 (3):447-448.
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  • Origin and Identity.Graeme Forbes - 1980 - Philosophical Studies 37 (4):353-62.
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