This article addresses the problem of emergence through a distinction, often neglected in the literature, between two different aspects of this issue: (1) the theoretical problem of providing modelizations able to explain the expression of emergent properties; (2) the epistemological problem of warranting the scientific value of the emergentist descriptions of nature. This paper considers this double issue with regard to the biological domain, and proposes a double solution (theoretical and epistemological) originally developed in early studies on self-organization. The underlying (...) hypothesis is that this solution offers the current biological emergentism the opportunity of developing a coherent structure: matching consistently the theoretical and the epistemological frames of the research, that is, coupling the emergentist conception of life with an emergentist conception of science. (shrink)

This paper argues that the consensus physicalist antireductionism in the philosophy of biology cannot accommodate the research strategy or indeed the recent findings of molecular developmental biology. After describing Wolperts programmatic claims on its behalf, and recent work by Gehring and others to identify the molecular determinants of development, the paper attempts to identify the relationship between evolutionary and developmental biology by reconciling two apparently conflicting accounts of bio-function – Wrights and Nagels (as elaborated by Cummins). Finally, the paper seeks (...) a way of defending the two central theses of physicalist antireductionism in the light of the research program of molecular developmental biology, by sharply reducing their metaphysical force. (shrink)

Although molecular biology has meant different things at different times, the term is often associated with a tendency to view cellular causation as conforming to simple linear schemas in which macro-scale effects are specified by micro-scale structures. The early achievements of molecular biologists were important for the formation of such an outlook, one to which the discovery of recombinant DNA techniques, and a number of other findings, gave new life even after the complexity of genotype–phenotype
relations had become apparent. Against this (...) background we outline how a range of scientific developments and conceptual considerations can be regarded as enabling and perhaps necessitating contemporary systems approaches. We suggest that philosophical ideas have a valuable part to play in making sense of complex scientific and disciplinary issues. (shrink)

In the context of scientists' reflections on genomics, we examine some fundamental issues in the emerging postgenomic discipline of systems biology. Systems biology is best understood as consisting of two streams. One, which we shall call ‘pragmatic systems biology’, emphasises large‐scale molecular interactions; the other, which we shall refer to as ‘systems‐theoretic biology’, emphasises system principles. Both are committed to mathematical modelling, and both lack a clear account of what biological systems are. We discuss the underlying issues in identifying systems (...) and how causality operates at different levels of organisation. We suggest that resolving such basic problems is a key task for successful systems biology, and that philosophers could contribute to its realisation. We conclude with an argument for more sociologically informed collaboration between scientists and philosophers. BioEssays 27:1270–1276, 2005. © 2005 Wiley Periodicals, Inc. (shrink)

It is frequently said that biology is emerging from a long phase of reductionism. It would be certainly more correct to say that biologists are abandoning a certain form of reductionism. We describe this past form, and the experiments which challenged the previous vision. To face the difficulties which were met, biologists use a series of concepts and metaphors - pleiotropy, tinkering, epigenetics - the ambiguity of which masks the difficulties, instead of solving them. In a similar way, the word (...) “post-genomics” has different meanings, depending upon who uses it. Which of these meanings will become dominant in the future is an open question. (shrink)

This paper argues in defense of theanti-reductionist consensus in the philosophy ofbiology. More specifically, it takes issues with AlexRosenberg's recent challenge of this position. Weargue that the results of modern developmentalgenetics rather than eliminating the need forfunctional kinds in explanations of developmentactually reinforce their importance.

University of Copenhagen University of Copenhagen University of Copenhagen Blegdamsvej 17 Njalsgade 80 Njalsgade 80 DK-2100 Copenhagen Ø DK 2300 Copenhagen S DK-2300 Copenhagen S Denmark.

Stuart Kauffman here presents a brilliant new paradigm for evolutionary biology, one that extends the basic concepts of Darwinian evolution to accommodate recent findings and perspectives from the fields of biology, physics, chemistry and mathematics. The book drives to the heart of the exciting debate on the origins of life and maintenance of order in complex biological systems. It focuses on the concept of self-organization: the spontaneous emergence of order widely observed throughout nature. Kauffman here argues that self-organization plays an (...) important role in the emergence of life itself and may play as fundamental a role in shaping life's subsequent evolution as does the Darwinian process of natural selection. Yet until now no systematic effort has been made to incorporate the concept of self-organization into evolutionary theory. The construction requirements which permit complex systems to adapt remain poorly understood, as is the extent to which selection itself can yield systems able to adapt more successfully. This book explores these themes. It shows how complex systems, contrary to expectations, can spontaneously exhibit stunning degrees of order, and how this order, in turn, is essential for understanding the emergence and development of life on Earth. Topics include the new biotechnology of applied molecular evolution, with its important implications for developing new drugs and vaccines; the balance between order and chaos observed in many naturally occurring systems; new insights concerning the predictive power of statistical mechanics in biology; and other major issues. Indeed, the approaches investigated here may prove to be the new center around which biologicalscience itself will evolve. The work is written for all those interested in the cutting edge of research in the life sciences. (shrink)

"_The Moment of Complexity_ is a profoundly original work. In remarkable and insightful ways, Mark Taylor traces an entirely new way to view the evolution of our culture, detailing how information theory and the scientific concept of complexity can be used to understand recent developments in the arts and humanities. This book will ultimately be seen as a classic."-John L. Casti, Santa Fe Institute, author of _Gödel: A Life of Logic, the Mind, and Mathematics_ The science of complexity accounts for (...) that inscrutable mix of chaos and order that governs our natural world. Complexity explains how networks emerge and function, how species organize into ecosystems, how stars form into galaxies, and how just a few sequences of DNA can account for so many different life forms. Recently, the idea of complexity has taken the worlds of business and politics by storm. The concept is used to account for phenomena as varied as the behavior of the stock market, the response of voting populations, and the effects of risk management. Even Disney has used complexity theory to manage crowd control at its theme parks. Given the startling development of new information technologies, we now live in a moment of unprecedented complexity, an era in which change occurs faster than our ability to comprehend it. With _The Moment of Complexity_, Mark C. Taylor offers a timely map for this unfamiliar terrain opening in our midst, unfolding an original philosophy through a remarkable synthesis of science and culture. According to Taylor, complexity is not just a breakthrough scientific concept, but the defining quality of the post-Cold War era. The flux of digital currents swirling around us, he argues, has created a new network culture with its own distinctive logic and dynamic. Drawing on resources from information theory and evolutionary biology, Taylor explains the operation of complex adaptive systems in social and cultural processes and captures a whole new zeitgeist in the making. To appreciate the significance of our emerging network culture, he claims, we need not only to understand contemporary scientific and technological transformations, but also to explore the subtle influences of art, architecture, philosophy, religion, and higher education. _The Moment of Complexity_, then, is a remarkable work of cultural analysis on a scale rarely seen today. To follow its trajectory is to learn how we arrived at this critical moment in our culture, and to know where we might head in the twenty-first century. (shrink)

Why has the problematic of complexity appeared so late? And why would it be justified?

The science of complexity is based on a new way of thinking that stands in sharp contrast to the philosophy underlying Newtonian science, which is based on reductionism, determinism, and objective knowledge. This paper reviews the historical development of this new world view, focusing on its philosophical foundations. Determinism was challenged by quantum mechanics and chaos theory. Systems theory replaced reductionism by a scientifically based holism. Cybernetics and postmodern social science showed that knowledge is intrinsically subjective. These developments are being (...) integrated under the header of “complexity science”. Its central paradigm is the multi-agent system. Agents are intrinsically subjective and uncertain about their environment and future, but out of their local interactions, a global organization emerges. Although different philosophers, and in particular the postmodernists, have voiced similar ideas, the paradigm of complexity still needs to be fully assimilated by philosophy. This will throw a new light on old philosophical issues such as relativism, ethics and the role of the subject. (shrink)

"Knowing how we know" is the subject of this book. Its authors present a new view of cognition that has important social and ethical implications, for, they assert, the only world we humans can have is the one we create together through the actions of our coexistence. Written for a general audience as well as for students, scholars, and scientists and abundantly illustrated with examples from biology, linguistics, and new social and cultural phenomena, this revised edition includes a new afterword (...) by Dr. Varela, in which he discusses the effect the book has had in the years since its first publication. (shrink)