A controversial scientific vision predicts a time in which humans and machines will merge and create a new form of non-biological intelligence, explaining how the occurrence will solve such issues as pollution, hunger, and aging.

The theory of nonlinear complex systems has become a successful and widely used problem-solving approach in the natural sciences - from laser physics, quantum chaos and meteorology to molecular modeling in chemistry and computer simulations of cell growth in biology. In recent times it has been recognized that many of the social, ecological and political problems of mankind are also of a global, complex and nonlinear nature. And one of the most exciting topics of present scientific and public interest is (...) the idea that even the human mind is governed largely by the nonlinear dynamics of complex systems. In this wide-ranging but concise treatment Prof. Mainzer discusses, in nontechnical language, the common framework behind these endeavours. Special emphasis is given to the evolution of new structures in natural and cultural systems and it is seen clearly how the new integrative approach of complexity theory can give new insights that were not available using traditional reductionistic methods. (shrink)

The term “synthetic biology” is a popular label of an emerging biotechnological field with strong claims to robustness, modularity, and controlled construction, finally enabling the creation of new organisms. Although the research community is heterogeneous, it advocates a common denominator that seems to define this field: the principles of rational engineering. However, it still remains unclear to what extent rational engineering—rather than “tinkering” or the usage of random based or non-rational processes—actually constitutes the basis for the techniques of synthetic biology. (...) In this article, we present the results of a quantitative bibliometric analysis of the realized extent of rational engineering in synthetic biology. In our analysis, we examine three issues: (1) We evaluate whether work at three levels of synthetic biology (parts, devices, and systems) is consistent with the principles of rational engineering. (2) We estimate the extent of rational engineering in synthetic biology laboratory practice by an evaluation of publications in synthetic biology. (3) We examine the methodological specialization in rational engineering of authors in synthetic biology. Our analysis demonstrates that rational engineering is prevalent in about half of the articles related to synthetic biology. Interestingly, in recent years the relative number of respective publications has decreased. Despite its prominent role among the claims of synthetic biology, rational engineering has not yet entirely replaced biotechnological methods based on “tinkering” and non-rational principles. (shrink)

This paper aims to contribute to the expanding discourse on inter- and transdisciplinarity. Referring to well-established distinctions in philosophy of science, the paper argues in favor of a plurality of four different dimensions: Interdisciplinarity with regard to objects, knowledge/theories, methods/practices, and further, problem perception/problem solving. Different philosophical thought traditions can be related to these distinguishable meanings. The philosophical framework of the four different dimensions will be illustrated by some of the most popular examples of research programs that are labeled interdisciplinary (...) : nanoresearch/nanoscience/nanotechnology, complex systems theory/chaos theory, biomimicry/bionics, and technology assessment/sustainability research. Thus, a minimal philosophy of science is required to understand and foster inter- and transdisciplinarity. (shrink)

The dual-use dilemma arises in the context of research in the biological and other sciences as a consequence of the fact that one and the same piece of scientific research sometimes has the potential to be used for bad as well as good purposes. It is an ethical dilemma since it is about promoting good in the context of the potential for also causing harm, e.g., the promotion of health in the context of providing the wherewithal for the killing of (...) innocents. It is an ethical dilemma for the researcher because of the potential actions of others, e.g., malevolent non-researchers who might steal dangerous biological agents, or make use of the original researcher’s work. And it is a dilemma for governments concerned with the security of their citizens, as well as their health. In this article we construct a taxonomy of types of “experiments of concern” in the biological sciences, and thereby map the terrain of ethical risk. We then provide a series of analyses of the ethical problems and considerations at issue in the dual-use dilemma, including the impermissibility of certain kinds of research and possible restrictions on dissemination of research results given the risks to health and security. Finally, we explore the main available institutional responses to some of the specific ethical problems posed by the dual-use dilemma in the biological sciences. (shrink)

Hans Jonas’ anti-visionary conservation-oriented environmental philosophy—prominently articulated in his seminal book The Imperative of Responsibility: In Search of an Ethics for the Technological Age —had a tremendous impact on public and philosophical debates throughout the 1980s and the 1990s. Jonas argues that the “environmental crisis” reveals an underlying fundamental “crisis” in the human-nature relation. The crisis challenges the metaphysical foundations of our Western culture—including the dominant way humans view and deal with nature. Environmental ethics, therefore, requires critical reflection on and (...) revision of the underlying philosophy of nature: ethics and philosophy of nature, Jonas argues, are twin sisters. This approach provokes severe criticism: the diagnosis objection, the origin analysis objection, the justification objection, and the problem-solution objection. Most objections are not as sound as they claim to be—although Jonas’ argumentative justification is in fact a bit weak. However, a systematic critique of the objections of the critics from an analytic perspective shows that he developed a political and practical “philosophy of nature” in which anthropology, ethics, and politics are conceptualized as a converging domain as one of the core constituents of environmentals ethics for this century. (shrink)

Ein großer Teil herkömmlicher Technikphilosophien basiert auf naturalistisch-anthropologischen Grundvorstellungen oder Handlungskonzepten, die bereits nach einem Grundmuster von Technik modelliert und insofern »technomorph« sind. Sie reflektieren nicht den eigenen Standpunkt. Die vorliegende Untersuchung ist der Frage gewidmet, inwiefern die Technizität unserer Weltbezüge hintergehbar ist bzw. was uns wie veranlasst, den Möglichkeitshorizont des Technischen näher zu erschließen. Als »Medialität des Technischen« ist dieser Gegenstand historischer und systematischer Analysen, die im ersten Band die theoretischen, im zweiten die praktischen Aspekte der Fragestellung behandeln. Dabei (...) werden die qualitativen Veränderungen herausgestellt, die die modernen Hochtechnologien aufweisen. (shrink)

In part one, I identify the core logical structure of the precautionary principle and distinguish it from the various key concepts that appear in the many different formulations of the principle. I survey these concepts and suggest a program of further conceptual analysis. In part two, I examine a particular version of the precautionary principle dubbed “the catastrophe principle” and criticize it in light of its similarities to the principle at work in Pascal’s Wager. I conclude with some suggestions for (...) advocates of the precautionary principle who wish their formulation to avoid the pitfalls confronting the catastrophe principle. (shrink)

A classic of phenomenology and existentialism and arguably Jonas's greatest work, The Phenomenon of Life sets forth a systematic and comprehensive philosophy -- ...

Review text: "Es gibt Bücher, die durch ihre unprätentiöse, stille und sorgfältige Vorgehensweise auf den ersten Blick über die Sensation hinwegtäuschen, die sie bloßlegen und zur Diskussion anbieten. So ein Buch ist die "Wissenschaftphilosophie? von Jan C. Schmidt, die über die "Instabilität in Natur und Wissenschaft? handelt."Günter Altner in: Naturwissenschaftliche Rundschau 9/2009.

The difference between a non-living machine such as a vacuum cleaner and a living organism as a lion seems to be obvious. The two types of entities differ in their material consistence, their origin, their development and their purpose. This apparently clear-cut borderline has previously been challenged by fictitious ideas of “artificial organism” and “living machines” as well as by progress in technology and breeding. The emergence of novel technologies such as artificial life, nanobiotechnology and synthetic biology are definitely blurring (...) the boundary between our understanding of living and non-living matter. This essay discusses where, at the borderline between living and non-living matter, we can position the future products of synthetic biology that belong to the two hybrid entities “synthetic organisms” and “living machines” and how the approaching realization of such hybrid entities affects our understanding of organisms and machines. For this purpose we focus on the description of three different types of synthetic biology products and the aims assigned to their realization: 1) synthetic minimal cells aimed at by protocell synthetic biology, 2) chassis organisms strived for by synthetic genomics and 3) genetically engineered machines produced by bioengineering. We argue that in the case of synthetic biology the purpose is more decisive for the categorization of a product as an organism or a machine than its origin and development. This has certain ethical implications because the definition of an entity as machine seems to allow bypassing the discussion about the assignment and evaluation of instrumental and intrinsic values, which can be raised in the case of organisms. (shrink)

The objective of this paper is to contribute to the expanding discourse on conceptual elements of TA. As a point of departure, it takes the recent transformation of the science, technology and innovation system ( technoscience ). We will show that the age of technoscience can be regarded as presenting not only a challenge, but also a chance and opportunity for TA. Embracing this opportunity, however, implies imposing several requirements on TA. In order to specify these requirements and to foster (...) the ongoing discourse on the foundations of TA, this paper suggests a programmatic term: prospective technology assessment (ProTA). This term is intended mainly as a reflection framework, aimed at providing an extension and complement—and not a replacement—of well-established TA concepts. Three requirements for ProTA are sketched: (1) early stage orientation—the temporal dimension, (2) intention and potential orientation—the knowledge dimension, (3) shaping orientation—the power/actor dimension. Examples from fusion and nano research will illustrate the need for ProTA, as well as its specific focus. The paper concedes that ProTA is in its infancy and that there is a clear need for further clarification. (shrink)