Advanced AI systems are rapidly making their way into medical research and practice, and, arguably, it is only a matter of time before they will surpass human practitioners in terms of accuracy, reliability, and knowledge. If this is true, practitioners will have a prima facie epistemic and professional obligation to align their medical verdicts with those of advanced AI systems. However, in light of their complexity, these AI systems will often function as black boxes: the details of their contents, calculations, (...) and procedures cannot be meaningfully understood by human practitioners. When AI systems reach this level of complexity, we can also speak of black-box medicine. In this paper, we want to argue that black-box medicine conflicts with core ideals of patient-centered medicine. In particular, we claim, black-box medicine is not conducive for supporting informed decision-making based on shared information, shared deliberation, and shared mind between practitioner and patient. (shrink)

Good luck isn’t just chance—it can be learned and leveraged—and The Serendipity Mindset explains how you can use serendipity to make life better at work, at home—everywhere. Many of us believe that the great turning points and opportunities in our lives happen by chance, that they’re out of our control. Often we think that successful people—and successful companies and organizations—are simply luckier than the rest of us. Good fortune—serendipity—just seems to happen to them. Is that true? Or are some people (...) better at creating the conditions for coincidences to arise and taking advantage of them when they do? How can we connect the dots of seemingly random events to improve our lives? In The Serendipity Mindset, Christian Busch explains that serendipity isn’t about luck in the sense of simple randomness. It’s about seeing links that others don’t, combining these observations in unexpected and strategic ways, and learning how to detect the moments when apparently random or unconnected ideas merge to form new opportunities. Busch explores serendipity from a rational and scientific perspective and argues that there are identifiable approaches we can use to foster the conditions to let serendipity grow. Drawing from biology, chemistry, management, and information systems, and using examples of people from all walks of life, Busch illustrates how serendipity works and explains how we can train our own serendipity muscle and use it to turn the unexpected into opportunity. Once we understand serendipity, Busch says, we become curators of it, and luck becomes something that no longer just happens to us—it becomes a force that we can grasp, shape, and hone. Full of exciting ideas and strategies, The Serendipity Mindset offers a clear blueprint for how we can cultivate serendipity to increase innovation, influence, and opportunity in every aspect of our lives. (shrink)

Serendipity is at the core of many innovationsInnovation, inventions, and entrepreneurial opportunities. However, despite its importance for organisations and individuals alike, research on the dimensions and antecedents of serendipity is surprisingly scarce. In this chapter, Christian Busch and Matthew Grimes review and synthesize research on serendipity in the entrepreneurshipEntrepreneurship, strategyStrategy, and innovationInnovation context, and suggest a novel conceptualisation of the processProcess of (cultivating) serendipity. They thereby provide the reader with a thorough and wide-ranging view of how serendipity has come (...) into the fore in the field of organization and management, but also what possibilities it opens up for understanding and creating the conditionsConditions for entrepreneurial success. They advance a processProcess-oriented model of serendipity that serves as a basis to elaborate factors that increase the chancesChance for serendipitous encounters and how to capitalize on them. Amongst those, Busch and Grimes distinguish between individual (including reframing, extrovertedness and perseverance) and organizational factors (including systematic evaluations, iteration and team-based collaboration). Their paper, thereby, advances the conceptual understanding of serendipity as much as a theory of how to transfer this understanding successfully into the entrepreneurial context. (shrink)

Breaking Down the Barriers to Serendipity Life is what happens to us while we are making other plans. ALLEN SAUNDERS, AMERICAN WRITER, JOURNALIST, AND CARTOONIST.

Algorithms are used across a wide range of societal sectors such as banking, administration, and healthcare to make predictions that impact on our lives. While the predictions can be incredibly accurate about our present and future behavior, there is an important question about how these algorithms in fact represent human identity. In this paper, we explore this question and argue that machine learning algorithms represent human identity in terms of what we shall call the statistical individual. This statisticalized representation of (...) individuals, we shall argue, differs significantly from our ordinary conception of human identity, which is tightly intertwined with considerations about biological, psychological, and narrative continuity—as witnessed by our most well-established philosophical views on personal identity. Indeed, algorithmic representations of individuals give no special attention to biological, psychological, and narrative continuity and instead rely on predictive properties that significantly exceed and diverge from those that we would ordinarily take to be relevant for questions about how we are. (shrink)

The 2013 Rostock Symposium on Systems Biology and Bioinformatics in Aging Research was again dedicated to dissecting the aging process using in silico means. A particular focus was on ontologies, as these are a key technology to systematically integrate heterogeneous information about the aging process. Related topics were databases and data integration. Other talks tackled modeling issues and applications, the latter including talks focussed on marker development and cellular stress as well as on diseases, in particular on diseases of kidney (...) and skin. (shrink)

The well-definedness of particles of any kind depends on the limits, approximations, or other conditions that may or may not be involved, for example, whether there are interactions and whether ostensibly related energy is localizable. In particular, their theoretical status differs between its non-relativistic and relativistic versions: One can properly define interacting elementary particles in single-system non-relativistic quantum mechanics, at least in the case of non-zero mass systems; by contrast, one is severely challenged to define even these properly in the (...) relativistic quantum field theories that now underlie the study of particle physics. Here, the impact of localizability on this status is reviewed in relation to the work of Paul Busch on positive operator valued measures that significantly probes the relevance of quantum unsharpness to it. (shrink)

Normally in nowadays philosophical research the term 'Neoplatonism' is coined and it was used the first time by Jacob Brucker in the first half of the 18th century. But there are signs that the concept is much older. So this essay follows the trace of the term 'Neoplatonism' from german philosophical historians, like Büsching and Brucker, back to the Cambridge Platonists and tries to demonstrate that the origin of the concept is based on some texts of the late antiquity which (...) act first on the research of the early modern philosophy. (shrink)

In a rather long piece which an exhibition catalog has called „catholic propaganda”(Busch & Maisak, 2013, p. 342), Guido Görres reflected on madness and art, using Kaulbach’s iconic 1835 drawing of asylum inmates (Das Narrenhaus) as pretext. Görres wrote of “this hospital of the human spirit (…), this charnel ground of the living, who like specters roam, wearing on their foreheads the faded and almost illegible traces of their former names.”1(1836, p. 9). Overdramatic prose, but unlikely to strike one (...) as unprecedented. If anything, it has long been customary to exhibit a mix of fascination and revulsion when discussing the institutions which in the past two centuries at the same time sheltered and shattered those deemed mentally ill. (shrink)