This article was initially written (in 2020) for a private collection gifted to Alexander García Düttmann on the occasion of his 60th birthday. It explores themes of education and the transmission of knowledge in relation to figures of youth and extinction. Georg Trakl's poem "Abendlied" serves as the essay's centerpiece and is brought into dialogue with comments made by Levi-Strauss on a 'prima material'. Certain ecological overtones appear when an overzealous Prometheanism is contrasted with a labor of re-creation.

The article sketches a view of nature as a movement undermining totality. Awareness of our entanglement in an inherently incomplete movement forces us to rethink or reinvent our relationship to nature. The view provided here has been developed by drawing heavily from the later work of Martin Heidegger, moving with and beyond it in an examination of the limitations of Western philosophy in approaching questions of nature and ecology. Thinking ecologically becomes a question of grammar and the binding (and unbinding) (...) force of language as it pertains to human thought and (or in) its physical environment. (shrink)

A comprehensive reading of Heidegger's work from the mid-1930s to the 1960s that seeks to develop an ecological thinking rooted in reflections on the Heraclitean 'hen', relationality, and the impossibility of totality. An elaboration of the structural homology between Heidegger's use of the terms 'Technik' and 'metaphysics' sets the stage for his later work or topology. The Spätwerk is presented as an irresolvable polarity between 'Technik' and 'Ereignis', between a totalizing movement and a movement of disruption. This serves as the (...) basis for reflections on human experience of and as the ecological. Nature as Limit serves as a contribution to both eco-philosophy and to philosophical methodology more broadly, with philological and hermeneutic excursions that engage the relationship between language and the ecological motifs being developed in the work. (shrink)

The environment can elicit biological responses such as oxidative stress (OS) and inflammation as a consequence of chemical, physical, or psychological changes. As population studies are essential for establishing these environment-organism interactions, biomarkers of OS or inflammation are critical in formulating mechanistic hypotheses. By using examples of stress induced by various mechanisms, we focus on the biomarkers that have been used to assess OS and inflammation in these conditions. We discuss the difference between biomarkers that are the result of a (...) chemical reaction (such as lipid peroxides or oxidized proteins that are a result of the reaction of molecules with reactive oxygen species) and those that represent the biological response to stress, such as the transcription factor NRF2 or inflammation and inflammatory cytokines. The high-throughput and holistic approaches to biomarker discovery used extensively in large-scale molecular epidemiological exposome are also discussed in the context of human exposure to environmental stressors. We propose to consider the role of biomarkers as signs and to distinguish between signs that are just indicators of biological processes and proxies that one can interact with and modify the disease process. (shrink)

The interview focuses on specific aspects of Giuseppe Cacciatore's philosophy, with particular emphasis on the connection between theoretical speculation and civil practice. As highlighted by philosopher Giuseppe Cantillo, Cacciatore' s works strive to combine thought and history at every point, starting with Pietro Piovani's 'critical-problematic historicism'. The outcome is a theoretical system that is aimed at civil and political commitment, while at the same time maintaining a genuinely ideal motivation.