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  1. Damage to the prefrontal cortex increases utilitarian moral judgements.Michael Koenigs, Liane Young, Ralph Adolphs, Daniel Tranel, Fiery Cushman, Marc Hauser & Antonio Damasio - 2007 - Nature 446 (7138):908-911.
    The psychological and neurobiological processes underlying moral judgement have been the focus of many recent empirical studies1–11. Of central interest is whether emotions play a causal role in moral judgement, and, in parallel, how emotion-related areas of the brain contribute to moral judgement. Here we show that six patients with focal bilateral damage to the ventromedial prefrontal cortex (VMPC), a brain region necessary for the normal generation of emotions and, in particular, social emotions12–14, produce an abnor- mally ‘utilitarian’ pattern of (...)
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  2. Utilitarian moral judgment in psychopathy.Michael Koenigs, Michael Kruepke, Joshua Zeier & Joseph Newman - 2011 - Social Cognitive and Affective Neuroscience (6):1-7.
    Psychopathic behavior is characteristically amoral, but to date research studies have largely failed to identify any systematic differences in moral judgment capability between psychopaths and non-psychopaths. In this study, we investigate whether significant differences in moral judgment emerge when taking into account the phenotypic heterogeneity of the disorder through a well-validated distinction between psychopathic subtypes. Three groups of incarcerated participants [low-anxious psychopaths (n 1⁄4 12), high-anxious psychopaths (n 1⁄4 12) and non-psychopaths (n 1⁄4 24)] completed a moral judgment test involving (...)
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  3. Inherent emotional quality of human speech sounds.Blake Myers-Schulz, Maia Pujara, Richard C. Wolf & Michael Koenigs - 2013 - Cognition and Emotion 27 (6):1105-1113.
    During much of the past century, it was widely believed that phonemes--the human speech sounds that constitute words--have no inherent semantic meaning, and that the relationship between a combination of phonemes (a word) and its referent is simply arbitrary. Although recent work has challenged this picture by revealing psychological associations between certain phonemes and particular semantic contents, the precise mechanisms underlying these associations have not been fully elucidated. Here we provide novel evidence that certain phonemes have an inherent, non-arbitrary emotional (...)
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  4. Economic decision-making in psychopathy: A comparison with ventromedial prefrontal lesion patients.Michael Koenigs, Michael Kruepke & Joseph P. Newman - 2010 - Neuropsychologia 48 (7):2198–2204.
    Psychopathy, which is characterized by a constellation of antisocial behavioral traits, may be subdivided on the basis of etiology: “primary” (low-anxious) psychopathy is viewed as a direct consequence of some core intrinsic deficit, whereas “secondary” (high-anxious) psychopathy is viewed as an indirect consequence of environmental factors or other psychopathology. Theories on the neurobiology of psychopathy have targeted dysfunction within ventromedial prefrontal cortex (vmPFC) as a putative mechanism, yet the relationship between vmPFC function and psychopathy subtype has not been fully explored. (...)
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  5. Altered Resting-State Functional Connectivity in Cortical Networks in Psychopathy.Carissa L. Philippi, Maia S. Pujara, Julian C. Motzkin, Joseph P. Newman, Kent A. Kiehl & Michael Koenigs - 2015 - The Journal of Neuroscience 35 (15):6068 – 6078.
    Psychopathy is a personality disorder characterized by callous antisocial behavior and criminal recidivism. Here we examine whether psychopathy is associated with alterations in functional connectivity in three large-scale cortical networks. Using fMRI in 142 adult male prison inmates, we computed resting-state functional connectivity using seeds from the default mode network, frontoparietal network, and cingulo-opercular network. To determine the specificity of our findings to these cortical networks, we also calculated functional connectivity using seeds from two comparison primary sensory networks: visual and (...)
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