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  1. Slowed ageing, welfare, and population problems.Christopher Wareham - 2015 - Theoretical Medicine and Bioethics 36 (5):321-340.
    Biological studies have demonstrated that it is possible to slow the ageing process and extend lifespan in a wide variety of organisms, perhaps including humans. Making use of the findings of these studies, this article examines two problems concerning the effect of life extension on population size and welfare. The first—the problem of overpopulation—is that as a result of life extension too many people will co-exist at the same time, resulting in decreases in average welfare. The second—the problem of underpopulation—is (...)
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  • Should We Replace Disabled Newborn Infants?Dominic Wilkinson - 2011 - Journal of Moral Philosophy 8 (3):390-414.
    If a disabled newborn infant dies, her parents may be able to conceive another child without impairment. This is sometimes referred to as 'replacement'. Some philosophers have argued that replacement provides a strong reason for disabled newborns to be killed or allowed to die. In this paper I focus on the case for replacement as it relates to decisions about life support in newborn intensive care. I argue (following Jeff McMahan) that the impersonal reason to replace is weak and easily (...)
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  • Bioethics transformed: 40 years of the value of life.David R. Lawrence - forthcoming - Cambridge Quarterly of Healthcare Ethics:1-12.
    This article examines the evolution of bioethics over the past four decades since the publication of John Harris’ seminal work, “The Value of Life” (1985). It argues that while the core principles articulated by Harris remain relevant, bioethics has undergone significant transformation across four key domains. First, the expanding frontiers of biotechnology have necessitated engagement with complex issues beyond individual clinical ethics. Second, there has been a widening of the circle of moral concern to encompass nonhuman animals, disability rights, and (...)
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  • Impairing the Impairment Argument.Kyle van Oosterum & Emma J. Curran - 2024 - Journal of Medical Ethics 50 (5):335-339.
    Blackshaw and Hendricks have recently developed and defended the impairment argument against abortion, arguing that the immorality of giving a child fetal alcohol syndrome (FAS) provides us with reason to believe that abortion is immoral. In this paper, we forward two criticisms of the impairment argument. First, we highlight that, as it currently stands, the argument is very weak and accomplishes very little. Second, we argue that Blackshaw and Hendricks are fundamentally mistaken about what makes giving a child FAS immoral. (...)
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  • Selektion zum Wohl des zukünftigen Kindes?: Präimplantationsdiagnostik, „prokreatives Wohltun“ und die Verantwortung angehender Eltern.Ruth Denkhaus - 2021 - Ethik in der Medizin 34 (1):27-48.
    Der Beitrag setzt sich kritisch mit dem Prinzip des prokreativen Wohltuns von Julian Savulescu und seinen Implikationen für den Umgang mit der Präimplantationsdiagnostik auseinander. PB fordert angehende Eltern dazu auf, aus mehreren möglichen zukünftigen Kindern dasjenige auszuwählen, dessen Leben voraussichtlich am besten verlaufen wird. Paare mit Kinderwunsch sind danach zumindest unter bestimmten Umständen moralisch verpflichtet, eine PID in Anspruch zu nehmen, um die Weitergabe genetisch bedingter Krankheiten zu verhindern. Die Auswahl von Embryonen im Rahmen einer PID kann jedoch nur dann (...)
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  • Affecting future individuals: Why and when germline genome editing entails a greater moral obligation towards progeny.Davide Battisti - 2021 - Bioethics 35 (5):1-9.
    Assisted reproductive technologies have greatly increased our control over reproductive choices, leading some bioethicists to argue that we face unprecedented moral obligations towards progeny. Several models attempting to balance the principle of procreative autonomy with these obligations have been proposed. The least demanding is the minimal threshold model (MTM), according to which every reproductive choice is permissible, except creating children whose lives will not be worth living. Hence, as long as the future child is likely to have a life worth (...)
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  • Etica eugeniei.Nicolae Sfetcu - manuscript
    Argumentele referitoare la înțelepciunea continuării experimentării genetice și posibilele efecte eugenice ale ingineriei genetice se încadrează în general în trei domenii: etica biomedicală, moralitatea și religia și legea. Utilizarea potențială a ingineriei genetice a readus în discuții eugenia din trecut în disputele despre bioetică. Există opinii conform cărora și programele de eugenie fără caracter coercitiv ar fi în mod inerent lipsite de etică. Principiul moral central al eticii biomedicale implică o obligație de a conferi beneficii și de a elimina daunele. (...)
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  • Évolution et éthique de l'eugénisme.Nicolae Sfetcu - manuscript
    Étant donné la définition de l'eugénisme, il est très difficile d'établir une distinction claire entre la science (médecine, ingénierie génétique) et l'eugénisme en tant que domaine inclus. Et pour définir une ligne sur laquelle l'ingénierie génétique ne devrait pas aller plus loin, conformément aux normes morales, juridiques et religieuses. Si nous acceptons l'aide de la génétique pour trouver des moyens de lutter contre le cancer, le diabète ou le VIH, nous acceptons également l'eugénisme positif tel qu'il est défini à présent. (...)
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  • Evolution and Ethics of Eugenics.Nicolae Sfetcu - 2018 - Bucharest, Romania: MultiMedia Publishing.
    As eugenics is defined, it is very difficult to make a clear distinction between science (medicine, genetic engineering) and eugenics as a included field. And to set a line over which genetic engineering should not go further, according to moral, legal and religious norms. If we accept the help of genetics in finding ways to fight cancer, diabetes, or HIV, we also accept positive eugenics as they are defined now. And if we accept genetic screening, and interventions on the unborn (...)
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  • Causing People to Exist and Saving People’s Lives.Jeff McMahan - 2013 - The Journal of Ethics 17 (1):5-35.
    Most people are skeptical of the claim that the expectation that a person would have a life that would be well worth living provides a reason to cause that person to exist. In this essay I argue that to cause such a person to exist would be to confer a benefit of a noncomparative kind and that there is a moral reason to bestow benefits of this kind. But this conclusion raises many problems, among which is that it must be (...)
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  • The new (liberal) eugenics.Nicolae Sfetcu - manuscript
    Despite the Nazi horrors, in 1953 the new eugenics was founded, when Watson and Crick postulated the double helix of DNA as the basis of chemical heredity. In 1961, scientists have deciphered the genetic code of DNA, laying the groundwork for code manipulation and the potential building of new life forms. After thirty years from the discovery of the DNA structure, the experimenters began to carry out the first clinical studies of human somatic cell therapy. The practice of prenatal genetic (...)
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  • Parental Responsibility: A Moving Target.Kristien Hens, Daniela Cutas & Dorothee Horstkötter - 2016 - In Kristien Hens, Daniela Cutas & Dorothee Horstkötter (eds.), Parental Responsibility in the Context of Neuroscience and Genetics. Cham: Springer International Publishing.
    Beliefs about the moral status of children have changed significantly in recent decades in the Western world. At the same time, knowledge about likely consequences for children of individual, parental, and societal choices has grown, as has the array of choices that (prospective) parents may have at their disposal. The intersection between these beliefs, this new knowledge, and these new choices has created a minefield of expectations from parents and a seemingly ever-expanding responsibility towards their children. Some of these new (...)
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  • Melhoramento humano biotecnocientífico: a escolha hermenêutica é uma maneira adequada de regulá-lo?Murilo Mariano Vilaça & Maria Clara Dias - 2013 - Veritas – Revista de Filosofia da Pucrs 58 (1):61-86.
    Uma forma de compreender o humano é pela sua biologia, a qual pode ser vista como ambígua. Por um lado, há características biológicas correlacionadas a capacidades extremamente especializadas e complexas, as quais abrem possibilidades que lhe são particulares, distinguindo-o ‘positivamente’ dos outros seres vivos. Por outro, como todo ser vivo, há características que tornam a vida humana finita e relativamente vulnerável, as quais costumam ser ‘negativamente’ interpretadas. Em ambos os casos, há características biológicas que, em si, não são boas nem (...)
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  • Animal Disenhancement in Moral Context.Korinn N. Murphy & William P. Kabasenche - 2018 - NanoEthics 12 (3):225-236.
    To mitigate animal suffering under industrial farming conditions, biotechnology companies are pursuing the development of genetically disenhanced animals. Recent advances in gene editing biotechnology have brought this to reality. In one of the first discussions of the ethics of disenhancement, Thompson argued that it is hard to find compelling reasons to oppose it. We offer an argument against disenhancement that draws upon parallels with human disenhancement, ecofeminism’s concern with the “logic of domination,” and a relational ethic that seeks to preserve (...)
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  • Evoluția și etica eugeniei.Nicolae Sfetcu - manuscript
    În acest articol încerc să argumentez opinia că, așa cum este definită eugenia, este foarte dificil de făcut o diferențiere clară între știință (medicină, ingineria genetică) și eugenie. Și de stabilit o linie peste care ingineria genetică nu ar trebui să treacă, conform unor norme morale, juridice și religioase. Atâta timp cât acceptăm ajutorul geneticii în găsirea unor modalități de combatere a cancerului, diabetului sau HIV, acceptăm în mod implicit și eugenia pozitivă, conform definiției actuale. Și atâta timp cât acceptăm (...)
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  • Procreative Beneficence, Intelligence, and the Optimization Problem.Ben Saunders - 2015 - Journal of Medicine and Philosophy 40 (6):653-668.
    According to the Principle of Procreative Beneficence, reproducers should choose the child, of those available to them, expected to have the best life. Savulescu argues reproducers are therefore morally obligated to select for nondisease traits, such as intelligence. Carter and Gordon recently challenged this implication, arguing that Savulescu fails to establish that intelligence promotes well-being. This paper develops two responses. First, I argue that higher intelligence is likely to contribute to well-being on most plausible accounts. Second, I argue that, even (...)
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  • Protecting the future child: Foetal alcohol spectrum disorder, easy rescue and the regulation of maternal behaviour.Catherine Mills - 2023 - Bioethics 37 (8):771-778.
    This paper argues that social contexts of inequality are crucial to understanding the ethics of gestational harm and responsibility. Recent debates on gestational harm have largely ignored the social context of gestators, including contexts of inequality and injustice. This can reinforce existing social injustices arising from colonialism, socio‐economic inequality and racism, for example, through increased regulation of maternal behaviour. To demonstrate this, I focus on the related notions of the ‘future child’ and an obligation of easy rescue, which have been (...)
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  • “Obligatory Technologies”: Explaining Why People Feel Compelled to Use Certain Technologies.Jennifer A. Chandler - 2012 - Bulletin of Science, Technology and Society 32 (4):255-264.
    The ideas of technological determinism and the autonomy of technology are long-standing and widespread. This article explores why the use of certain technologies is perceived to be obligatory, thus fueling the fatalism of technological determinism and undermining our sense of freedom vis-à-vis the use of technologies. Three main mechanisms that might explain “obligatory technologies” (technologies that must be adopted) are explored. First, competition between individuals or groups drives the adoption of technologies that enhance or extend human capacities. Second, individuals and (...)
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  • Impersonalism in Bioethics.Robert Ranisch - 2012 - American Journal of Bioethics 12 (8):40 - 41.
    The American Journal of Bioethics, Volume 12, Issue 8, Page 40-41, August 2012.
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  • The Topsy-Turvy Cloning Law.Iain Brassington & Stuart Oultram - 2011 - Monash Bioethics Review 29 (3):1-18.
    In debates about human cloning, a distinction is frequently drawn between therapeutic and reproductive uses of the technology. Naturally enough, this distinction influences the way that the law is framed. The general consensus is that therapeutic cloning is less morally problematic than reproductive cloning — one can hold this position while holding that both are morally unacceptable — and the law frequently leaves the way open for some cloning for the sake of research into new therapeutic techniques while banning it (...)
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  • The proper scope of the principle of procreative beneficence revisited.Søren Holm & Rebecca Bennett - 2014 - Monash Bioethics Review 32 (1-2):22-32.
    The principle of procreative beneficence, first suggested by Julian Savulescu, argues that: If couples have decided to have a child, and selection is possible, then they have a significant moral reason to select the child, of the possible children they could have, whose life is expected, in light of the relevant available information, to go best or at least not worse than any of the others. While the validity of this moral principle has been widely contested, in this paper we (...)
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  • What is the harm in harmful conception? On threshold harms in non-identity cases.Nicola J. Williams & John Harris - 2014 - Theoretical Medicine and Bioethics 35 (5):337-351.
    Has the time come to put to bed the concept of a harm threshold when discussing the ethics of reproductive decision making and the legal limits that should be placed upon it? In this commentary, we defend the claim that there exist good moral reasons, despite the conclusions of the non-identity problem, based on the interests of those we might create, to refrain from bringing to birth individuals whose lives are often described in the philosophical literature as ‘less than worth (...)
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  • Is procreative beneficence obligatory?Ben Saunders - 2015 - Journal of Medical Ethics 41 (2):175-178.
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  • Balancing Procreative Autonomy and Parental Responsibility.Tom Buller & Stephanie Bauer - 2011 - Cambridge Quarterly of Healthcare Ethics 20 (2):268-276.
    In Rationality and the Genetic Challenge: Making People Better? Matti Häyry provides a clear and informed discussion and analysis of a number of competing answers to the above questions. Häyry describes three main perspectives on the morality of prenatal genetic diagnosis , the “restrictive,” “moderate,” and “permissive” views, and his analysis illuminates that these views can be distinguished in terms of their different “rationalities”—their respective understanding of what counts as a reasonable choice for parents to make in light of PGD.
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  • A critical view on using “life not worth living” in the bioethics of assisted reproduction.Agnes Elisabeth Kandlbinder - 2024 - Medicine, Health Care and Philosophy 27 (2):189-203.
    This paper critically engages with how life not worth living (LNWL) and cognate concepts are used in the field of beginning-of-life bioethics as the basis of arguments for morally requiring the application of preimplantation genetic diagnosis (PGD) and/or germline genome editing (GGE). It is argued that an objective conceptualization of LNWL is largely too unreliable in beginning-of-life cases for deriving decisive normative reasons that would constitute a moral duty on the part of intending parents. Subjective frameworks are found to be (...)
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  • Is the non-identity problem relevant to public health and policy? An online survey.Keyur Doolabh, Lucius Caviola, Julian Savulescu, Michael J. Selgelid & Dominic Wilkinson - 2019 - BMC Medical Ethics 20 (1):1-17.
    The non-identity problem arises when our actions in the present could change which people will exist in the future, for better or worse. Is it morally better to improve the lives of specific future people, as compared to changing which people exist for the better? Affecting the timing of fetuses being conceived is one case where present actions change the identity of future people. This is relevant to questions of public health policy, as exemplified in some responses to the Zika (...)
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  • Possible Persons and the Problem of Prenatal Harm.Nicola Jane Williams - 2013 - The Journal of Ethics 17 (4):355-385.
    When attempting to determine which of our acts affect future generations and which affect the identities of those who make up such generations, accounts of personal identity that privilege psychological features and person affecting accounts of morality, whilst highly useful when discussing the rights and wrongs of acts relating to extant persons, seem to come up short. On such approaches it is often held that the intuition that future persons can be harmed by decisions made prior to their existence is (...)
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  • Biotransformação ou biomelhoramento: entre fatos e valores.Murilo Mariano Vilaça & Maria Clara Dias - 2021 - Hybris, Revista de Filosofí­A 12 (1):61-82.
    The generic idea that the human should enhance seems uncontroversial. However, there is a great controversy about the meaning of enhance and the means that should be used. The possibilities of enhance humans through the use of biotechnology are a central theme of the current bioethical debate. Human Enhancement is the concept used to translate the idea that a biotransformation would generate a bioenhancement. In this article, we present a proposal for a factual-elementary framework of the generic concept of human (...)
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  • Reasons, Persons, Eugenics and an Argument in Favour of Gene Editing.Rebecca Bennett - 2024 - American Journal of Bioethics 24 (8):37-40.
    Volume 24, Issue 8, August 2024, Page 37-40.
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  • Is Gene Editing Harmless? Two Arguments for Gene Editing.Julian Savulescu & Marcos Alonso - 2022 - American Journal of Bioethics 22 (9):23-28.
    … the decision to genome edit will almost certainly be identity affecting, as a couple (or individual) will usually make it before they have created any embryos and the process itself will, at the...
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  • „Hauptsache das Kind ist gesund?“ – Ethische und rechtliche Fragen am Lebensanfang.Ruth Denkhaus & Julia Inthorn - 2021 - Ethik in der Medizin 34 (1):1-6.
    Der Beitrag setzt sich kritisch mit dem Prinzip des prokreativen Wohltuns von Julian Savulescu und seinen Implikationen für den Umgang mit der Präimplantationsdiagnostik auseinander. PB fordert angehende Eltern dazu auf, aus mehreren möglichen zukünftigen Kindern dasjenige auszuwählen, dessen Leben voraussichtlich am besten verlaufen wird. Paare mit Kinderwunsch sind danach zumindest unter bestimmten Umständen moralisch verpflichtet, eine PID in Anspruch zu nehmen, um die Weitergabe genetisch bedingter Krankheiten zu verhindern. Die Auswahl von Embryonen im Rahmen einer PID kann jedoch nur dann (...)
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  • Healthy people and biochemical enhancement: A new paradigmatic approach to the enhancement of human beings?Martin Farbák & Zlatica Plašienková - 2021 - Ethics and Bioethics (in Central Europe) 11 (3-4):231-239.
    The authors analyse a new paradigmatic approach to the enhancement of human beings proposed in transhumanist visions. Transhumanist authors promote the biochemical enhancement of healthy people via the concepts of bio-happiness and bio-love. The paper is based on an assessment of the value attributed to the lives of disabled people vis-à-vis those of healthy people. The value imbalance in the transhumanist conception is criticized on the grounds that it is an incorrect response to the posthuman urge to redefine human beings. (...)
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  • Failures of Imagination: Disability and the Ethics of Selective Reproduction.Marta Soniewicka - 2015 - Bioethics 29 (8):557-563.
    The article addresses the problem of disability in the context of reproductive decisions based on genetic information. It poses the question of whether selective procreation should be considered as a moral obligation of prospective parents. To answer this question, a number of different ethical approaches to the problem are presented and critically analysed: the utilitarian; Julian Savulescu's principle of procreative beneficence; the rights-based. The main thesis of the article is that these approaches fail to provide any appealing principles on which (...)
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  • Let Us Assume That Gene Editing is Safe—The Role of Safety Arguments in the Gene Editing Debate.Søren Holm - 2019 - Cambridge Quarterly of Healthcare Ethics 28 (1):100-111.
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  • Damaging the Future: The Health Rights of Children and the Issue of Short-Termism; Issues Facing Australian Bioethicists.Sally Dalton-Brown - 2018 - Cambridge Quarterly of Healthcare Ethics 27 (3):440-446.
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  • Reasons, Rationalities, and Procreative Beneficence: Need Häyry Stand Politely By While Savulescu and Herissone-Kelly Disagree?Peter Herissone-Kelly - 2011 - Cambridge Quarterly of Healthcare Ethics 20 (2):258-267.
    The claim that the answers we give to many of the central questions in genethics will depend crucially upon the particular rationality we adopt in addressing them is central to Matti Häyry’s thorough and admirably fair-minded book, Rationality and the Genetic Challenge. That claim implies, of course, that there exists a plurality of rationalities, or discrete styles of reasoning, that can be deployed when considering concrete moral problems. This, indeed, is Häyry’s position. Although he believes that there are certain features (...)
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  • Assisted gestative technologies.Elizabeth Chloe Romanis - 2022 - Journal of Medical Ethics 48 (7):439-446.
    A large body of literature considers the ethico-legal and regulatory issues surrounding assisted conception. Surrogacy, however, within this body of literature is an odd-fit. It involves a unique demand of another person—a form of reproductive labour—that many other aspects of assisted conception, such as gamete donation do not involve. Surrogacy is a form of assisted gestation. The potential alternatives for individuals who want a genetically related child but who do not have the capacity to gestate are ever increasing: with the (...)
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  • Synthesizing Methuselah: The Question of Artificial Agelessness.Richard B. Gibson - 2024 - Cambridge Quarterly of Healthcare Ethics 33 (1):60-75.
    As biological organisms, we age and, eventually, die. However, age’s deteriorating effects may not be universal. Some theoretical entities, due to their synthetic composition, could exist independently from aging—artificial general intelligence (AGI). With adequate resource access, an AGI could theoretically be ageless and would be, in some sense, immortal. Yet, this need not be inevitable. Designers could imbue AGIs with artificial mortality via an internal shut-off point. The question, though, is, should they? Should researchers curtail an AGI’s potentially endless lifespan (...)
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