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  1. The implications of Methylphenidate use by healthy medical students and doctors in South Africa.Chad Beyer, Ciara Staunton & Keymanthri Moodley - 2014 - BMC Medical Ethics 15 (1):20.
    The use of medical stimulants to sustain attention, augment memory and enhance intellectual capacity is increasing in society. The use of Methylphenidate for cognitive enhancement is a subject that has received much attention in the literature and academic circles in recent times globally. Medical doctors and medical students appear to be equally involved in the off-label use of Methylphenidate. This presents a potential harm to society and the individual as the long-term side effect profile of this medication is unknown.
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  • Public Attitudes Toward Cognitive Enhancement.Nicholas S. Fitz, Roland Nadler, Praveena Manogaran, Eugene W. J. Chong & Peter B. Reiner - 2013 - Neuroethics 7 (2):173-188.
    Vigorous debate over the moral propriety of cognitive enhancement exists, but the views of the public have been largely absent from the discussion. To address this gap in our knowledge, four experiments were carried out with contrastive vignettes in order to obtain quantitative data on public attitudes towards cognitive enhancement. The data collected suggest that the public is sensitive to and capable of understanding the four cardinal concerns identified by neuroethicists, and tend to cautiously accept cognitive enhancement even as they (...)
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  • Autonomy and the Unintended Legal Consequences of Emerging Neurotherapies.Jennifer A. Chandler - 2011 - Neuroethics 6 (2):249-263.
    One of the ethical issues that has been raised recently regarding emerging neurotherapies is that people will be coerced explicitly or implicitly in the workplace or in schools to take cognitive enhancing drugs. This article builds on this discussion by showing how the law may pressure people to adopt emerging neurotherapies. It focuses on a range of private law doctrines that, unlike the criminal law, do not come up very often in neuroethical discussions. Three doctrines—the doctrine of mitigation, the standard (...)
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  • Begging important questions about cognitive enhancement, again.Wayne Hall, Jonathan Finnoff, Jayne Lucke & Brad Partridge - 2011 - American Journal of Bioethics 11 (1):14 - 15.
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  • Moral enhancement and freedom.John Harris - 2010 - Bioethics 25 (2):102-111.
    This paper identifies human enhancement as one of the most significant areas of bioethical interest in the last twenty years. It discusses in more detail one area, namely moral enhancement, which is generating significant contemporary interest. The author argues that so far from being susceptible to new forms of high tech manipulation, either genetic, chemical, surgical or neurological, the only reliable methods of moral enhancement, either now or for the foreseeable future, are either those that have been in human and (...)
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  • Enhanced Humans versus "Normal People": Elusive Definitions.M. Bess - 2010 - Journal of Medicine and Philosophy 35 (6):641-655.
    A key aspect of transhumanist thought involves the modification or augmentation of human physical and mental capabilities—a form of intervention often encapsulated under the term "enhancement." This article provides an overview of the concept of enhancement, focusing on six major areas in which usages of the term become slippery and controversial: normal or species-typical functioning, therapeutics or healing, natural functioning, human nature, authenticity, and the ambiguity between "more" and "better." I argue that we need to be aware of the tendency (...)
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  • ‘Cosmetic Neurology’ and the Moral Complicity Argument.A. Ravelingien, J. Braeckman, L. Crevits, D. De Ridder & E. Mortier - 2009 - Neuroethics 2 (3):151-162.
    Over the past decades, mood enhancement effects of various drugs and neuromodulation technologies have been proclaimed. If one day highly effective methods for significantly altering and elevating one’s mood are available, it is conceivable that the demand for them will be considerable. One urgent concern will then be what role physicians should play in providing such services. The concern can be extended from literature on controversial demands for aesthetic surgery. According to Margaret Little, physicians should be aware that certain aesthetic (...)
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  • Deep Brain Stimulation as a Probative Biology: Scientific Inquiry and the Mosaic Device.Joseph J. Fins - 2012 - American Journal of Bioethics Neuroscience 3 (1):4-8.
    Building upon an earlier critique of the Food and Drug Adminstration (FDA) granting of a humanitarian device exemption for deep brain stimulation in treatment-resistant obsessive compulsive disorder, this article considers how we regulate and finance DBS. It suggests that these devices are mosaic in nature: both potentially therapeutic and probative and that their dual roles need to be appreciated to maximize their therapeutic and investigational potential.
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  • Freedom of thought at the ethical frontier of law & science.Marcus Moore - 2022 - Ethics and Behavior 32 (6):510-531.
    ABSTRACT Some of the most compelling contemporary ethical questions surround 21st Century neuroscientific technologies. Among these, neurocognitive intervention technologies allow an unprecedented ability to alter thought. Concerns exist about their impact on individual freedom, behavior and personhood. They could also distort society, eroding core values of dignity, equality, and diversity. Potent laws are needed to anchor regulation in this rising field. The article explores how the long-neglected human right of Freedom of Thought might protect the integrity of the mind at (...)
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  • What an International Declaration on Neurotechnologies and Human Rights Could Look like: Ideas, Suggestions, Desiderata.Jan Christoph Bublitz - 2024 - American Journal of Bioethics Neuroscience 15 (2):96-112.
    International institutions such as UNESCO are deliberating on a new standard setting instrument for neurotechnologies. This will likely lead to the adoption of a soft law document which will be the first global document specifically tailored to neurotechnologies, setting the tone for further international or domestic regulations. While some stakeholders have been consulted, these developments have so far evaded the broader attention of the neuroscience, neurotech, and neuroethics communities. To initiate a broader debate, this target article puts to discussion twenty-five (...)
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  • Neuroethics at 15: Keep the Kant but Add More Bacon.Gabriel Lázaro-Muñoz, Peter Zuk, Stacey Pereira, Kristin Kostick, Laura Torgerson, Demetrio Sierra-Mercado, Mary Majumder, J. Blumenthal-Barby, Eric A. Storch, Wayne K. Goodman & Amy L. McGuire - 2019 - American Journal of Bioethics Neuroscience 10 (3):97-100.
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  • Fooled by ‘smart drugs’ – why shouldn’t pharmacological cognitive enhancement be liberally used in education?Magen Inon - 2018 - Ethics and Education 14 (1):54-69.
    ABSTRACTResearch shows that various pharmaceuticals can offer modest cognition enhancing effects for healthy individuals. These finding have caused some academics to support liberal use of pharmacological cognitive enhancement in schools and universities. This approach partially arises from arguments implying there is little moral justification for regulating such drugs. In this paper, I argue against the liberal use of PCE on epistemic grounds. According to Charles Taylor, emotions and behaviour are epistemically valuable because they tell us meaningful things about reality. Hence, (...)
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  • Begging the Question: Presupposing That TMS Can Be Shown to Enhance Eyewitness Testimony.Jayne C. Lucke & Wayne D. Hall - 2010 - American Journal of Bioethics Neuroscience 1 (3):34-35.
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  • Academic Doping: Institutional Policies Regarding Nonmedical use of Prescription Stimulants in U.S. Higher Education.Ross Aikins, Xiaoxue Zhang & Sean Esteban McCabe - 2017 - Journal of Academic Ethics 15 (3):229-243.
    Academic integrity policies at 200 institutions of higher education were examined for the presence of academic prohibitions against the nonmedical use of prescription stimulants or any other cognitive enhancing drug. Researchers used online search tools to locate policy handbooks in a stratified random sample of IHE’s drawn from the Integrated Postsecondary Education Data System database, searching for NMUPS/CED use as violations of either academic integrity or alcohol and other drug policies. Of 191 academic integrity policies found online, NMUPS/CED prohibitions were (...)
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  • A Comparison of Attitudes Toward Pharmacological Treatment Versus Enhancement Under Competitive and Noncompetitive Conditions.Jeffrey M. Rudski - 2014 - AJOB Empirical Bioethics 5 (2):80-90.
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  • Technological unemployment and human disenhancement.Michele Loi - 2015 - Ethics and Information Technology 17 (3):201-210.
    This paper discusses the concept of “human disenhancement”, i.e. the worsening of human individual abilities and expectations through technology. The goal is provoking ethical reflection on technological innovation outside the biomedical realm, in particular the substitution of human work with computer-driven automation. According to some widely accepted economic theories, automatization and computerization are responsible for the disappearance of many middle-class jobs. I argue that, if that is the case, a technological innovation can be a cause of “human disenhancement”, globally, and (...)
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  • Does Amphetamine Enhance Your Health? On the Distinction between Health and “Health-like” Enhancements.Per-Anders Tengland - 2015 - Journal of Medicine and Philosophy 40 (5):484-510.
    It is an imperative within health care, medicine, and public health to restore, preserve, and enhance health. Therefore, it is important to determine what kinds of enhancement are increases in health and what kinds are not. Taking as its point of departure two conceptions of health, namely, “manifest health” and “fundamental health,” the paper discusses various means used to enhance ability and well-being, and if those means, such as wheelchairs, implants, medicines, stimulants, or narcotics, enhance health. The fact that some (...)
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  • The Myth of Cognitive Enhancement Drugs.Hazem Zohny - 2015 - Neuroethics 8 (3):257-269.
    There are a number of premises underlying much of the vigorous debate on pharmacological cognitive enhancement. Among these are claims in the enhancement literature that such drugs exist and are effective among the cognitively normal. These drugs are deemed to enhance cognition specifically, as opposed to other non-cognitive facets of our psychology, such as mood and motivation. The focus on these drugs as cognitive enhancers also suggests that they raise particular ethical questions, or perhaps more pressing ones, compared to those (...)
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  • Cognitive neuroenhancement: false assumptions in the ethical debate.Andreas Heinz, Roland Kipke, Hannah Heimann & Urban Wiesing - 2012 - Journal of Medical Ethics 38 (6):372-375.
    The present work critically examines two assumptions frequently stated by supporters of cognitive neuroenhancement. The first, explicitly methodological, assumption is the supposition of effective and side effect-free neuroenhancers. However, there is an evidence-based concern that the most promising drugs currently used for cognitive enhancement can be addictive. Furthermore, this work describes why the neuronal correlates of key cognitive concepts, such as learning and memory, are so deeply connected with mechanisms implicated in the development and maintenance of addictive behaviour so that (...)
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  • The use of methylphenidate among students: the future of enhancement?S. M. Outram - 2010 - Journal of Medical Ethics 36 (4):198-202.
    During the past few years considerable debate has arisen within academic journals with respect to the use of smart drugs or cognitive enhancement pharmaceuticals. The following paper seeks to examine the foundations of this cognitive enhancement debate using the example of methylphenidate use among college students. The argument taken is that much of the enhancement debate rests upon inflated assumptions about the ability of such drugs to enhance and over-estimations of either the size of the current market for such drugs (...)
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  • Neuroethics : what else is new?Alex Mauron - unknown
    Bioethics has changed considerably over the years, the increasing diversity of topics of bioethical interest having led to specialisation if not fragmentation. In this context the term “neuroethics" emerged, and it soon became clear that it could be understood in two ways. The “ethics of neuroscience” assesses the ethical and philosophical implications of research in neuroscience and of the application of these discoveries, especially as regards enhancement of “normal” human faculties or new challenges to privacy. The “neuroscience of ethics” basically (...)
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  • Pharmacological cognitive enhancement : how neuroscientific research could advance ethical debate.Hannah Maslen, Nadira Faulmüller & Julian Savulescu - unknown
    There are numerous ways people can improve their cognitive capacities: good nutrition and regular exercise can produce long-term improvements across many cognitive domains, whilst commonplace stimulants such as coffee temporarily boost levels of alertness and concentration. Effects like these have been well-documented in the medical literature and they raise few ethical issues. More recently, however, clinical research has shown that the off-label use of some pharmaceuticals can, under certain conditions, have modest cognition-improving effects. Substances such as methylphenidate and modafinil can (...)
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  • Towards a Smart Population: A Public Health Framework for Cognitive Enhancement.Jayne Lucke & Brad Partridge - 2012 - Neuroethics 6 (2):419-427.
    This paper presents a novel view of the concept of cognitive enhancement by taking a population health perspective. We propose four main modifiable healthy lifestyle factors for optimal cognitive functioning across the population for which there is evidence of safety and efficacy. These include i) promoting adequate sleep, ii) increasing physical activity, iii) encouraging a healthy diet, including minimising consumption of stimulants, alcohol and other drugs including nicotine, iv) and promoting good mental health. We argue that it is not ethical (...)
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  • Republication: In that case. [REVIEW]Jayne Lucke - 2010 - Journal of Bioethical Inquiry 7 (4):381-382.
    This Article was originally published in Journal of Bioethical Inquiry 7(3): 337-338, http://dx.doi.org/10.1007/s11673-010-9247-1 . It is reprinted here for the sake of coherence.
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  • In That Case.Jayne Lucke - 2010 - Journal of Bioethical Inquiry 7 (3):337-338.
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  • Deflating the Neuroenhancement Bubble.Jayne C. Lucke, Stephanie Bell, Brad Partridge & Wayne D. Hall - 2011 - American Journal of Bioethics Neuroscience 2 (4):38-43.
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  • The Biopolitical Embodiment of Work in the Era of Human Enhancement.Nicolas Le Dévédec - 2020 - Body and Society 26 (1):55-81.
    Human enhancement or the use of technoscientific and biomedical advances to improve human performance is a social phenomenon that has become increasingly significant in Western societies over the last 15 years or so, notably in the workplace. By focusing on the non-medical use of psychostimulants, and from a perspective that is both critical and exploratory, this article aims to show that human enhancement practices prefigure new forms of embodiment and interiorization of work that are contributing to a significant reconfiguration of (...)
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  • Can Neuromodulation also Enhance Social Inequality? Some Possible Indirect Interventions of the State.Andrea Lavazza - 2017 - Frontiers in Human Neuroscience 11.
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  • Cognitive Enhancements and the Values of Higher Education.Matt Lamkin - 2012 - Health Care Analysis 20 (4):347-355.
    Drugs developed to treat cognitive impairments are proving popular with healthy college students seeking to boost their focus and productivity. Concerned observers have called these practices a form of cheating akin to athletes’ use of steroids, with some proposing testing students’ urine to deter “academic doping.” The ease with which critics analogize the academic enterprise to competitive sport, and the impulse to crack down on students using study drugs, reflect the same social influences and trends that spur demand for these (...)
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  • Intellectual Doping and Pharmaceutical Cognitive Enhancement in Education: Some Ethical Questions.Zdenko Kodelja - 2021 - Journal of Philosophy of Education 55 (1):167-185.
    Journal of Philosophy of Education, EarlyView.
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  • To ELSI or Not to ELSI Neuroscience: Lessons for Neuroethics from the Human Genome Project.Eran Klein - 2010 - American Journal of Bioethics Neuroscience 1 (4):3-8.
    The Ethical, Legal, and Social Implications (ELSI) program of the Human Genome Project stands as a model for how to organize bioethical inquiry for a rapidly changing field. Neuroscience has experienced significant growth in recent years and there is increasing interest in organizing critical reflection on this field, as evidenced by the creation of “neuroethics.” A nascent framework for reflection on the implications of neuroscience is emerging but significant work remains, given the pace and scope of neuroscientific developments. The adoption (...)
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  • Rethinking “Cognitive” Enhancement: The Ethical Stakes of User Perspectives.Fred B. Ketchum - 2013 - American Journal of Bioethics Neuroscience 4 (1):26-27.
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  • Neuroethics Needs an International Human Rights Deliberative Frame.Luis Justo & Fabiana Erazun - 2010 - American Journal of Bioethics Neuroscience 1 (4):17-18.
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  • Australian University Students’ Coping Strategies and Use of Pharmaceutical Stimulants as Cognitive Enhancers.Charmaine Jensen, Cynthia Forlini, Brad Partridge & Wayne Hall - 2016 - Frontiers in Psychology 7.
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  • In Service to Others: A New Evolutionary Perspective on Human Enhancement.Hugh Desmond - 2021 - Hastings Center Report 51 (6):33-43.
    In enhancement ethics, evolutionary theory has been largely perceived as supporting liberal views on enhancement, where decisions to enhance are predominantly regulated by the principle of individual autonomy. In this paper I critique this perception in light of recent scientific developments. Cultural evolutionary theory suggests a picture where individual interests are entangled with community interests, and this undermines the applicability of the principle of autonomy. This is particularly relevant for enhancement ethics, given how – I argue – decisions to enhance (...)
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  • Cognitive enhancement by drugs in health and disease.Masud Husain & Mitul A. Mehta - 2011 - Trends in Cognitive Sciences 15 (1):28-36.
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  • The need for interdisciplinary dialogue in developing ethical approaches to neuroeducational research.Paul A. Howard-Jones & Kate D. Fenton - 2011 - Neuroethics 5 (2):119-134.
    This paper argues that many ethical issues in neuroeducational research cannot be appropriately addressed using the principles and guidance available in one of these areas alone, or by applying these in simple combination. Instead, interdisciplinary and public dialogue will be required to develop appropriate normative principles. In developing this argument, it examines neuroscientific and educational perspectives within three broad categories of ethical issue arising at the interface of cognitive neuroscience and education: issues regarding the carrying out of interdisciplinary research, the (...)
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  • 技術的進歩と民主的社会変革の融合の可能性.Shinnosuke Horiuchi - 2020 - Journal of the Japan Association for Philosophy of Science 47 (2):97-107.
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  • Virtue(al) games—real drugs.John T. Holden, Anastasios Kaburakis & Joanna Wall Tweedie - 2018 - Sport, Ethics and Philosophy 13 (1):19-32.
    The growth of esports as a recognized, organized, competitive activity in North America and Europe has evolved steadily from one of the most prominent sport industries in several Asian countries. Esports, which is still pursuing a widely accepted governance structure, has struggled to control the factors that typically act as a breeding ground for sport corruption. Within the esports industry, there is alleged widespread use of both prescription and off-label use of stimulants, such as modafinil, methylphenidate, and dextroamphetamine. Anti-doping policy (...)
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  • State Neutrality and Psychopharmacological Enhancement.Elisabeth Hildt - 2010 - American Journal of Bioethics Neuroscience 1 (2):51-52.
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  • Attitudes Toward Cognitive Enhancement: The Role of Metaphor and Context.Erin C. Conrad, Stacey Humphries & Anjan Chatterjee - 2019 - American Journal of Bioethics Neuroscience 10 (1):35-47.
    The widespread use of stimulants among healthy individuals to improve cognition has received growing attention; however, public attitudes toward this practice are not well understood. We determined the effect of framing metaphors and context of use on public opinion toward cognitive enhancement. We recruited 3,727 participants from the United States to complete three surveys using Amazon’s Mechanical Turk between April and July 2017. Participants read vignettes describing an individual using cognitive enhancement, varying framing metaphors (fuel versus steroid), and context of (...)
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  • What It’s Like to Be Good.John Harris - 2012 - Cambridge Quarterly of Healthcare Ethics 21 (3):293-305.
    In this issue of CQ we introduce a new feature, in which noted bioethicists are invited to reflect on vital current issues. Our first invitee, John Harris, will subsequently assume editorship of this section.
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  • Taking the “Human” Out of Human Rights.John Harris - 2011 - Cambridge Quarterly of Healthcare Ethics 20 (1):9-20.
    Human rights are universally acknowledged to be important, although they are, of course, by no means universally respected. This universality has helped to combat racism and sexism and other arbitrary and vicious forms of discrimination. Unfortunately, as we shall see, the universality of human rights is both too universal and not universal enough. It is time to take the “human” out of human rights. Indeed, it is very probable that in the future there will be no more humans as we (...)
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  • Constraints on Regulatory Options for Putatively Cognitive Enhancing Drugs.Wayne Hall, Brad Partridge & Jayne Lucke - 2013 - American Journal of Bioethics 13 (7):35-37.
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  • Some First Steps Toward Responsible Use of Cognitive-Enhancing Drugs by the Healthy.Henry T. Greely - 2013 - American Journal of Bioethics 13 (7):39-41.
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  • Staying in the Loop: Relational Agency and Identity in Next-Generation DBS for Psychiatry.Sara Goering, Eran Klein, Darin D. Dougherty & Alik S. Widge - 2017 - American Journal of Bioethics Neuroscience 8 (2):59-70.
    In this article, we explore how deep brain stimulation (DBS) devices designed to “close the loop”—to automatically adjust stimulation levels based on computational algorithms—may risk taking the individual agent “out of the loop” of control in areas where (at least apparent) conscious control is a hallmark of our agency. This is of particular concern in the area of psychiatric disorders, where closed-loop DBS is attracting increasing attention as a therapy. Using a relational model of identity and agency, we consider whether (...)
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  • Neuroenhancing public health.David Shaw - 2014 - Journal of Medical Ethics 40 (6):389-391.
    One of the most fascinating issues in the emerging field of neuroethics is pharmaceutical cognitive enhancement. The three main ethical concerns around CE were identified in a Nature commentary in 2008 as safety, coercion and fairness; debate has largely focused on the potential to help those who are cognitively disabled, and on the issue of ‘cosmetic neurology’, where people enhance not because of a medical need, but because they want to. However, the potential for CE to improve public health has (...)
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  • The Evaluation of Psychopharmacological Enhancers Beyond a Normative “Natural”–“Artificial” Dichotomy.Jakov Gather - 2011 - Medicine Studies 3 (1):19-27.
    The extra-therapeutic use of psychotropic drugs to improve cognition and to enhance mood has been the subject of controversial discussion in bioethics, in medicine but also in public for many years. Concerns over a liberal dealing with pharmacological enhancers are raised not only from a biomedical–pharmacological perspective, but particularly from an ethical one. Within these ethical concerns, there is one objection about the normative differentiation between “natural” and “artificial” enhancers, which is theoretically indeed widely discredited in bioethics, which has, however, (...)
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  • Moral and social reasons to acknowledge the use of cognitive enhancers in competitive-selective contexts.Mirko D. Garasic & Andrea Lavazza - 2016 - BMC Medical Ethics 17 (1):1-12.
    BackgroundAlthough some of the most radical hypothesis related to the practical implementations of human enhancement have yet to become even close to reality, the use of cognitive enhancers is a very tangible phenomenon occurring with increasing popularity in university campuses as well as in other contexts. It is now well documented that the use of cognitive enhancers is not only increasingly common in Western countries, but also gradually accepted as a normal procedure by the media as well. In fact, its (...)
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  • The Multiplicity of Memory Enhancement: Practical and Ethical Implications of the Diverse Neural Substrates Underlying Human Memory Systems.Kieran C. R. Fox, Nicholas S. Fitz & Peter B. Reiner - 2016 - Neuroethics 10 (3):375-388.
    The neural basis of human memory is incredibly complex. We argue that the diversity of neural systems underlying various forms of memory suggests that any discussion of enhancing ‘memory’ per se is too broad, thus obfuscating the biopolitical debate about human enhancement. Memory can be differentiated into at least four major systems with largely dissociable neural substrates. We outline each system, and discuss both the practical and the ethical implications of these diverse neural substrates. In practice, distinct neural bases imply (...)
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