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  1. The manipulability of what? The history of G-protein coupled receptors.Ann-Sophie Barwich & Karim Bschir - 2017 - Biology and Philosophy 32 (6):1317-1339.
    This paper tells the story of G-protein coupled receptors, one of the most important scientific objects in contemporary biochemistry and molecular biology. By looking at how cell membrane receptors turned from a speculative concept into a central element in modern biochemistry over the past 40 years, we revisit the role of manipulability as a criterion for entity realism in wet-lab research. The central argument is that manipulability as a condition for reality becomes meaningful only once scientists have decided how to (...)
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  • Science and Fiction: Analysing the Concept of Fiction in Science and its Limits.Ann-Sophie Barwich - 2013 - Journal for General Philosophy of Science / Zeitschrift für Allgemeine Wissenschaftstheorie 44 (2):357-373.
    A recent and growing discussion in philosophy addresses the construction of models and their use in scientific reasoning by comparison with fiction. This comparison helps to explore the problem of mediated observation and, hence, the lack of an unambiguous reference of representations. Examining the usefulness of the concept of fiction for a comparison with non-denoting elements in science, the aim of this paper is to present reasonable grounds for drawing a distinction between these two kinds of representation. In particular, my (...)
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  • Catherine Wilson's the invisible world: Early modern philosophy and the invention of the microscope.Brian S. Baigrie - 1998 - International Studies in the Philosophy of Science 12 (2):165 – 174.
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  • Kuhn's paradigm as a parable for the cold war: Incommensurability and its discontents from Fuller's tale of Harvard to Fleck's unsung lvov.Babette Babich - 2003 - Social Epistemology 17 (2 & 3):99 – 109.
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  • Understanding Interdisciplinary Corroboration: Lessons from a Review Paper in the Mind-Brain Sciences.Jaclyn Lanthier - unknown
    The current view of the relationship between areas of the mind-brain sciences is one where cross-disciplinary collaboration is required to advance claims about the mind-brain that stand on firm epistemic footing. My goal in this dissertation is to analyze what it means for information from different areas of science to fit together to produce strong epistemic claims by addressing how and to what extent claims about the mind-brain are corroborated in scientific practice. Philosophers of science have advanced various concepts of (...)
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  • A verisimilitudinarian analysis of the Linda paradox.Gustavo Cevolani, Vincenzo Crupi & Roberto Festa - 2012 - VII Conference of the Spanish Society for Logic, Methodology and Philosphy of Science.
    The Linda paradox is a key topic in current debates on the rationality of human reasoning and its limitations. We present a novel analysis of this paradox, based on the notion of verisimilitude as studied in the philosophy of science. The comparison with an alternative analysis based on probabilistic confirmation suggests how to overcome some problems of our account by introducing an adequately defined notion of verisimilitudinarian confirmation.
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  • What should a connectionist philosophy of science look like?William P. Bechtel - 1996 - In Robert N. McCauley (ed.), The Churchlands and Their Critics. Oxford University Press. pp. 121--144.
    The reemergence of connectionism2 has profoundly altered the philosophy of mind. Paul Churchland has argued that it should equally transform the philosophy of science. He proposes that connectionism offers radical and useful new ways of understanding theories and explanations.
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  • Taking Ontology Seriously : Quine's Thesis of Holism and Underdetermination Applied to the Sciences in the Age of Technoscience.Victoria Höög - unknown
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  • Ecological Hierarchy and Biodiversity.Christopher Lean & Kim Sterelny - 2016 - In Justin Garson, Anya Plutynski & Sahotra Sarkar (eds.), The Routledge Handbook of Philosophy of Biodiversity. London: Routledge. pp. 56 - 68.
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  • Scientific Realism and Primordial Cosmology.Feraz Azhar & Jeremy Butterfield - unknown
    We discuss scientific realism from the perspective of modern cosmology, especially primordial cosmology: i.e. the cosmological investigation of the very early universe. We first state our allegiance to scientific realism, and discuss what insights about it cosmology might yield, as against "just" supplying scientific claims that philosophers can then evaluate. In particular, we discuss: the idea of laws of cosmology, and limitations on ascertaining the global structure of spacetime. Then we review some of what is now known about the early (...)
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  • Productive Theory-Ladenness in fMRI.Emrah Aktunc - forthcoming - Synthese.
    Several developments for diverse scientific goals, mostly in physics and physiology, had to take place, which eventually gave us fMRI as one of the central research paradigms of contemporary cognitive neuroscience. This technique stands on solid foundations established by the physics of magnetic resonance and the physiology of hemodynamics and is complimented by computational and statistical techniques. I argue, and support using concrete examples, that these foundations give rise to a productive theory-ladenness in fMRI, which enables researchers to identify and (...)
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  • How models represent.James Nguyen - 2016 - Dissertation,
    Scientific models are important, if not the sole, units of science. This thesis addresses the following question: in virtue of what do scientific models represent their target systems? In Part i I motivate the question, and lay out some important desiderata that any successful answer must meet. This provides a novel conceptual framework in which to think about the question of scientific representation. I then argue against Callender and Cohen’s attempt to diffuse the question. In Part ii I investigate the (...)
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  • Scientific models, simulation, and the experimenter's regress.Axel Gelfert - 2011 - In Paul Humphreys & Cyrille Imbert (eds.), Models, Simulations, and Representations. Routledge.
    According to the "experimenter's regress", disputes about the validity of experimental results cannot be closed by objective facts because no conclusive criteria other than the outcome of the experiment itself exist for deciding whether the experimental apparatus was functioning properly or not. Given the frequent characterization of simulations as "computer experiments", one might worry that an analogous regress arises for computer simulations. The present paper analyzes the most likely scenarios where one might expect such a "simulationist's regress" to surface, and, (...)
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  • Seventh Workshop on the Philosophy of Information. Conceptual Challenges of Data in Science and Technology. [REVIEW]Canali Stefano - 2015 - Rivista Italiana di Filosofia Analitica Junior 6 (1):64-86.
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  • Method Pluralism, Method Mismatch, & Method Bias.Adrian Currie & Shahar Avin - 2019 - Philosophers' Imprint 19.
    Pluralism about scientific method is more-or-less accepted, but the consequences have yet to be drawn out. Scientists adopt different methods in response to different epistemic situations: depending on the system they are interested in, the resources at their disposal, and so forth. If it is right that different methods are appropriate in different situations, then mismatches between methods and situations are possible. This is most likely to occur due to method bias: when we prefer a particular kind of method, despite (...)
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  • Legacy Data, Radiocarbon Dating, and Robustness Reasoning.Alison Wylie - manuscript
    *PSA 2016, symposium on “Data in Time: Epistemology of Historical Data” organized by Sabina Leonelli, 5 November 2016* *See published version: "Radiocarbon Dating in Archaeology: Triangulation and Traceability" in Data Journeys in the Sciences (2020) - link below* Archaeologists put a premium on pressing “legacy data” into service, given the notoriously selective and destructive nature of their practices of data capture. Legacy data consist of material and records that been assembled over decades, sometimes centuries, often by means and for purposes (...)
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  • When can a Computer Simulation act as Substitute for an Experiment? A Case-Study from Chemisty.Johannes Kästner & Eckhart Arnold - manuscript
    In this paper we investigate with a case study from chemistry under what conditions a simulation can serve as a surrogate for an experiment. The case-study concerns a simulation of H2-formation in outer space. We find that in this case the simulation can act as a surrogate for an experiment, because there exists comprehensive theoretical background knowledge in form of quantum mechanics about the range of phenomena to which the investigated process belongs and because any particular modelling assumptions as can (...)
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  • Tools for Evaluating the Consequences of Prior Knowledge, but no Experiments. On the Role of Computer Simulations in Science.Eckhart Arnold - manuscript
    There is an ongoing debate on whether or to what degree computer simulations can be likened to experiments. Many philosophers are sceptical whether a strict separation between the two categories is possible and deny that the materiality of experiments makes a difference (Morrison 2009, Parker 2009, Winsberg 2010). Some also like to describe computer simulations as a “third way” between experimental and theoretical research (Rohrlich 1990, Axelrod 2003, Kueppers/Lenhard 2005). In this article I defend the view that computer simulations are (...)
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  • Empirical thought experiments: A trascendental-operational view.Buzzoni Marco - 2010 - Epistemologia. An Italian Journal for the Philosophy of Science 33:05-26.
    The operational perspective here defended permits a reflexive-transcendental point of view that sharply distinguishes the two concepts, while, at the same time, maintaining the connection between them. On the one hand, simply imagining that the experimental apparatus, counterfactually anticipated in a thought experiment, has really been constructed is sufficient to erase any difference between thought and real experiments. On the other hand, this very ‘imagining’, this capacity of the mind to assume every real entity as a possible entity, underpins the (...)
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  • Legal Questions and Scientific Answers : Ontological Differences and Epistemic Gaps in the Assessment of Causal Relations.Lena Wahlberg - 2010 - Dissertation, Lund University
    A large number of legal rules create an obligation to prevent, repair or otherwise mitigate damage to human health or the environment. Many of these rules require that a legally relevant causal relation between human behaviour and the damage at issue is established, and in the establishment of causal relations of this kind scientific information is often pressed into service. This thesis examines this specifically legal use of scientific information. It shows that many legally relevant causal relations cannot be established (...)
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  • Comités 2.0: deberes, posibilidades y desafíos de la ética institucionalizada en el s. XXI.Armando Menéndez Viso & Antonio Casado da Rocha - 2011 - Dilemata 5:163-180.
    Ethics committees are one of the main agents in the governance of science and technology, especially in the field of health care. This paper analyses some aspects of their nature, which show the internal relationship between the moral and the scientific-technological domains. Being both knowledge providers and users thereof, ethics committees deliberate and decide on complex contemporary ethical issues. To pursue their aims, they require adequate technical tools in order to deliberate and choose using new technologies of communication and information. (...)
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