In what sense are the activities and properties of components in a mechanism explanatorily relevant to the behavior of a mechanism as a whole? I articulate this problem, the problem of constitutive relevance, and I show that it must be solved if we are to understand mechanisms and mechanistic explanation. I argue against some putative solutions to the problem of constitutive relevance, and I sketch a positive account according to which relevance is analyzed in terms ofrelationships of mutual manipulability between (...) the behavior of a mechanism as a whole and the properties and activities of its components. My account is a causal-mechanical account in the sense that it is a particular expression of the idea that constitutive explanation is a matter of showing how an explanandum phenomenon is situated within the causal structure of the world. It is thus offered as a rival to epistemic (argument-centered) and psychological accounts of interlevel explanation. (shrink)

For over 20 years, Jaegwon Kim’s Causal Exclusion Argument has stood as the major hurdle for non-reductive physicalism. If successful, Kim’s argument would show that the high-level properties posited by non-reductive physicalists must either be identical with lower-level physical properties, or else must be causally inert. The most prominent objection to the Causal Exclusion Argument—the so-called Overdetermination Objection—points out that there are some notions of causation that are left untouched by the argument. If causation is simply counterfactual dependence, for example, (...) then the Causal Exclusion Argument fails. Thus, much of the existing debate turns on the issue of which account of causation is appropriate. In this paper, however, I take a bolder approach and argue that Kim’s preferred version of the Causal Exclusion Argument fails no matter what account one gives of causation. Any notion of causation that is strong enough to support the premises of the argument is too strong to play the role required in the logic of the argument. I also consider a second version of the Causal Exclusion Argument, and suggest that although it may avoid the problems of the first version, it begs the question against a particular form of non-reductive physicalism, namely emergentism. (shrink)

Many epistemic anomalies of the neoclassical research programme originate from its ontologically reductionist meta-axioms, which predicate how economic macro-systems are constituted from their micr...

Philosophers of neuroscience have traditionally described interfield integration using reduction models. Such models describe formal inferential relations between theories at different levels. I argue against reduction and for a mechanistic model of interfield integration. According to the mechanistic model, different fields integrate their research by adding constraints on a multilevel description of a mechanism. Mechanistic integration may occur at a given level or in the effort to build a theory that oscillates among several levels. I develop this alternative model using (...) a putative exemplar of reduction in contemporary neuroscience: the relationship between the psychological phenomena of learning and memory and the electrophysiological phenomenon known as Long-Term Potentiation. A new look at this historical episode reveals the relative virtues of the mechanistic model over reduction as an account of interfield integration. (shrink)

In recent years, a change in attitude in particle physics has led to our understanding current quantum field theories as effective field theories. The present paper is concerned with the significance of this EFT approach, especially from the viewpoint of the debate on reductionism in science. In particular, it is a purpose of this paper to clarify how EFTs may provide an interesting case-study in current philosophical discussion on reduction, emergence and inter-level relationships in general.

In recent years, a ''change in attitude'' in particle physics has led to our understanding current quantum field theories as effective field theories (EFTs). The present paper is concerned with the significance of this EFT approach, especially from the viewpoint of the debate on reductionism in science. In particular, I shall show how EFTs provide a new and interesting case study in current philosophical discussion on reduction, emergence, and inter-level relationships in general.

Functional decomposition is an important goal in the life sciences, and is central to mechanistic explanation and explanatory reduction. A growing literature in philosophy of science, however, has challenged decomposition-based notions of explanation. ‘Holists’ posit that complex systems exhibit context-sensitivity, dynamic interaction, and network dependence, and that these properties undermine decomposition. They then infer from the failure of decomposition to the failure of mechanistic explanation and reduction. I argue that complexity, so construed, is only incompatible with one notion of decomposition, (...) which I call ‘atomism’, and not with decomposition writ large. Atomism posits that function ascriptions must be made to parts with minimal reference to the surrounding system. Complexity does indeed falsify atomism, but I contend that there is a weaker, ‘contextualist’ notion of decomposition that is fully compatible with the properties that holists cite. Contextualism suggests that the function of parts can shift with external context, and that interactions with other parts might help determine their context-appropriate functions. This still admits of functional decomposition within a given context. I will give examples based on the notion of oscillatory multiplexing in systems neuroscience. If contextualism is feasible, then holist inferences are faulty—one cannot infer from the presence of complexity to the failure of decomposition, mechanism, and reductionism. (shrink)

Despite the ubiquity of “levels of organization” in the scientific literature, a nascent “levels skepticism” now claims that the concept of levels is an inherently flawed, misleading, or otherwise inadequate notion for understanding how life scientists produce knowledge about the natural world. However, levels skeptics rely on the maligned “layer-cake” account of levels stemming from Oppenheim and Putnam’s defense of the unity of science for their critical commentary. Recourse to layer-cake levels is understandable, as it is arguably the default conception (...) of levels in philosophy. However, relying on this conception of levels undermines the initial plausibility of general dismissals of the concept, because the problems skeptics identify within the “basic idea” of the concept “levels” are merely ones already widely acknowledged in this conception. I illustrate this “guilt by association” by looking at the embedded role of “levels” in articulating intertheoretical reductionism during the latter part of the 20th century. I conclude by suggesting a methodological framework focusing on local usage patterns as a promising means for future analysis of the levels concept. (shrink)

Instances of explanatory reduction are often advocated on metaphysical grounds; given that the only real things in the world are subatomic particles and their interaction, we have to try to explain everything in terms of the laws of physics. In this paper, we show that explanatory reduction cannot be defended on metaphysical grounds. Nevertheless, indispensability arguments for reductive explanations can be developed, taking into account actual scientific practice and the role of epistemic interests. Reductive explanations might be indispensable to address (...) some epistemic interest answering a specific explanation-seeking question in the most accurate, adequate and efficient way. Just like explanatory pluralists often advocate the indispensability of higher levels of explanation pointing at the pragmatic value of the explanatory information obtained on these higher levels, we argue that explanatory reduction—traditionally understood as the contender of pluralism—can be defended in a similar way. The pragmatic value reductionist, lower level explanations might have in the biomedical sciences and the social sciences is illustrated by some case studies. (shrink)

Contemporary philosophy of science has seen a growing trend towards a focus on scientific practice over the epistemic outputs that such practices produce. This practice-oriented approach has yielded a clearer understanding of how reductive research strategies play a central role in contemporary scientific inquiry. In parallel, a growing body of work has sought to explore the role of non-reductive, or systems-level, research strategies. As a result, the relationship between reductive and non-reductive scientific practices is becoming of increased importance. In this (...) paper, I provide a framework within which research strategies can be compared. I argue that no strategy is reductive or non-reductive simpliciter, rather strategies are more, or are less, reductive than one another according to a frame of reference. That frame of reference is provided by a continuum of possible ways in which the target system might be conceptualised. I illustrate the utility of the framework by deploying it to analyse a recent debate in cancer research. When set within the framework, a prominent reductive strategy—the somatic mutation theory—and a prominent non-reductive strategy—the tissue organisational field theory—do not stand opposed to one another. Rather, they serve as boundary markers to chart the territory of approaches to carcinogenesis within which most strategies in the field fall. (shrink)

In grappling with the micro-macro problem in sociology, philosophers of the field are finding it increasingly useful to associate micro-sociology with theory reduction. In this article I argue that the association is ungrounded and undesirable. Although of a reductive "disposition," micro-sociological theories instantiate something more like "reductive explanation," whereby the causal roles of social wholes are explained in terms of their psychological parts. In this form, micro-sociological theories may actually have a better shot at closing the sociology–psychology explanatory gap, and (...) resist many antireductionist arguments, including the well-known argument from "multiple realization.". (shrink)

Reduction and reductionism have been central philosophical topics in analytic philosophy of science for more than six decades. Together they encompass a diversity of issues from metaphysics and epistemology. This article provides an introduction to the topic that illuminates how contemporary epistemological discussions took their shape historically and limns the contours of concrete cases of reduction in specific natural sciences. The unity of science and the impulse to accomplish compositional reduction in accord with a layer-cake vision of the sciences, the (...) seminal contributions of Ernest Nagel on theory reduction and how they strongly conditioned subsequent philosophical discussions, and the detailed issues pertaining to different accounts of reduction that arise in both physical and biological science (e.g., limit-case and part-whole reduction in physics, the difference-making principle in genetics, and mechanisms in molecular biology) are explored. The conclusion argues that the epistemological heterogeneity and patchwork organization of the natural sciences encourages a pluralist stance about reduction. (shrink)

Schaffner’s model of theory reduction has played an important role in philosophy of science and philosophy of biology. Here, the model is found to be problematic because of an internal tension. Indeed, standard antireductionist external criticisms concerning reduction functions and laws in biology do not provide a full picture of the limits of Schaffner’s model. However, despite the internal tension, his model usefully highlights the importance of regulative ideals associated with the search for derivational, and embedding, deductive relations among mathematical (...) structures in theoretical biology. A reconstructed Schaffnerian model could therefore shed light on mathematical theory development in the biological sciences and on the epistemology of mathematical practices more generally. *Received November 2006; revised March 2009. †To contact the author, please write to: Philosophy Department, University of California, Santa Cruz, 1156 High St., Santa Cruz, CA 95064; e‐mail: [email protected]. (shrink)

A scientific explanatory project, part-whole explanation, and a kind of science, part-whole science are premised on identifying, investigating, and using parts and wholes. In the biological sciences, mechanistic, structuralist, and historical explanations are part-whole explanations. Each expresses different norms, explananda, and aims. Each is associated with a distinct partitioning frame for abstracting kinds of parts. These three explanatory projects can be complemented in order to provide an integrative vision of the whole system, as is shown for a detailed case study: (...) the tetrapod limb. My diagnosis of part-whole explanation in the biological sciences as well as in other domains exploring evolved, complex, and integrated systems (e.g., psychology and cognitive science) cross-cuts standard philosophical categories of explanation: causal explanation and explanation as unification. Part-whole explanation is itself one essential aspect of part-whole science. (shrink)

Most philosophical accounts of emergence are incompatible with reduction. Most scientists regard a system property as emergent relative to properties of its parts if it depends upon their mode of organization-a view consistent with reduction. Emergence is a failure of aggregativity, in which ``the whole is nothing more than the sum of its parts''. Aggregativity requires four conditions, giving powerful tools for analyzing modes of organization. Differently met for different decompositions of the system, and in different degrees, the structural conditions (...) can provide evaluation criteria for choosing decompositions, ``natural kinds'', and detecting functional localization fallacies, approximations, and various biases of vulgar reductionisms. This analysis of emergence and use of these conditions as heuristics is consistent with a broader reductionistic methodology. (shrink)

Richard Levins’ distinction between aggregate, composed and evolved systems acquires new significance as we recognize the importance of mechanistic explanation. Criteria for aggregativity provide limiting cases for absence of organization, so through their failure, can provide rich detectors for organizational properties. I explore the use of failures of aggregativity for the analysis of mechanistic systems in diverse contexts. Aggregativity appears theoretically desireable, but we are easily fooled. It may be exaggerated through approximation, conditions of derivation, and extrapolating from some conditions (...) of decomposition illegtimately to others. Evolved systems particularly may require analyses under alternative complementary decompositions. Exploring these conditions helps us to better understand the strengths and limits of reductionistic methods. (shrink)

Nagel’s official model of theory-reduction and the way it is represented in the literature are shown to be incompatible with the careful remarks on the notion of reduction Nagel gave while developing his model. Based on these remarks, an alternative model is outlined which does not face some of the problems the official model faces. Taking the context in which Nagel developed his model into account, it is shown that the way Nagel shaped his model and, thus, its well-known deficiencies, (...) are best conceived of as a mere by-product of his philosophical background. (shrink)

Instances of explanatory reduction are often advocated on metaphysical grounds; given that the only real things in the world are subatomic particles and their interaction, we have to try to explain everything in terms of the laws of physics. In this paper, we show that explanatory reduction cannot be defended on metaphysical grounds. Nevertheless, indispensability arguments for reductive explanations can be developed, taking into account actual scientific practice and the role of epistemic interests. Reductive explanations might be indispensable to address (...) some epistemic interest answering a specific explanation-seeking question in the most accurate, adequate and efficient way. Just like explanatory pluralists often advocate the indispensability of higher levels of explanation pointing at the pragmatic value of the explanatory information obtained on these higher levels, we argue that explanatory reduction—traditionally understood as the contender of pluralism—can be defended in a similar way. The pragmatic value reductionist, lower level explanations might have in the biomedical sciences and the social sciences is illustrated by some case studies. (shrink)

We introduce a new model of reduction inspired by Kemeny and Oppenheim’s model [Kemeny & Oppenheim 1956] and argue that this model is operative in a “ruthlessly reductive” part of current neuroscience. Kemeny and Oppenheim’s model was quickly rejected in mid-20th-century philosophy of science and replaced by models developed by Ernest Nagel and Kenneth Schaffner [Nagel 1961], [Schaffner 1967]. We think that Kemeny and Oppenheim’s model was correctly rejected, given what a “theory of reduction” was supposed to account for at (...) that time. But their guiding insights about what constitutes scientific reduction—increases in explanatory scope and systematization—reflect actual practices of current reductionistic neuroscience. The key rehabilitative step to make their insights fit current scientific details is to restate them using resources from recent work on causal-mechanistic explanation. We begin with a scientific case study, drawn from the relatively new field of “molecular and cellular cognition”. It provides an explanation of the well-known Ebbinghaus spacing effect on learning and memory in terms of interactions between a transcriptional enhancer protein and its inhibiting phosphatase in neurons recruited into the memory trace. Next we briefly describe some popular models of reduction from mid-20th-century philosophy of science. We point out how these models fail to illuminate key features of our scientific case study. Finally we present our causal-mechanistically updated Kemeny and Oppenheim-inspired model and argue that it nicely accounts for the details of our scientific case study. We close with a remark that will hopefully undercut the surprise many may feel to learn that a long-rejected philosophical account of reduction actually is at work in one of the most prominent reductionistic endeavors in current science. (shrink)

This paper examines the nature of theory structure in biology and considers the implications of those theoretical structures for theory reduction. An account of biological theories as interlevel prototypes embodying causal sequences, and related to each other by strong analogies, is presented, and examples from the neurosciences are provided to illustrate these middle-range theories. I then go on to discuss several modifications of Nagel''s classical model of theory reduction, and indicate at what stages in the development of reductions these models (...) might best apply. Finally I consider several implications of these analyses of theory structure and reduction for disciplinary integration in biology. (shrink)

The author draws on arguments from contemporary philosophy of mind to provide an argument for sociological collectivism. This argument for nonreductive individualism accepts that only individuals exist but rejects methodological individualism. In Part I, the author presents the argument for nonreductive individualism by working through the implications of supervenience, multiple realizability, and wild disjunction in some detail. In Part II, he extends the argument to provide a defense for social causal laws, and this account of social causation does not require (...) any commitment to intentionality or agency on the part of individuals. (shrink)

This article is a systematic critical survey of work done in the philosophy of biology within the logical empiricist tradition, beginning in the 1930s and until the end of the 1950s. It challenges a popular view that the logical empiricists either ignored biology altogether or produced analyses of little value. The earliest work on the philosophy of biology within the logical empiricist corpus was that of Philipp Frank, Ludwig von Bertalanffy, and Felix Mainx. Mainx, in particular, provided a detailed analysis (...) of biology in the 1930s and 1940s in his contribution to the logical empiricists’ Encyclopedia of Unified Science. However, the most important contributions to the philosophy of biology were those of Joseph Henry Woodger and Ernest Nagel. Woodger is primarily remembered for deploying the axiomatic method in biology but he also used semiformal methods for the analysis of many biological problems. While Woodger’s axiomatic work was often derided by some later philosophers of biology (e.g., David Hull and Michael Ruse), this article defends both the biological and the philosophical significance of some of that work, for instance, those aspects that led to the recognition of the conceptual complexity of mereology and temporal identity in biological systems. Woodger’s semiformal analyses were even more important, for instance, his explication of the concepts of the Bauplan and of innateness. Nagel’s importance lies in his analyses of reduction and emergence in the context of all empirical sciences and his use of these analyses in a careful exploration of biological problems. While Nagel’s model of reduction was generally rejected by philosophers of science in the 1970s and 1980s, particularly for biological contexts, it has recently been sympathetically reconstructed by many commentators; this article defends its continued relevance for the philosophy of biology. (shrink)

This paper attempts a critical reappraisal of Nagel's (1961, 1970) model of reduction taking into account both traditional criticisms and recent defenses. This model treats reduction as a type of explanation in which a reduced theory is explained by a reducing theory after their relevant representational items have been suitably connected. In accordance with the deductive-nomological model, the explanation is supposed to consist of a logical deduction. Nagel was a pluralist about both the logical form of the connections between the (...) reduced and reducing theories (which could be conditionals or biconditionals) and their epistemological status (as analytic connections, conventions, or synthetic claims). This paper defends Nagel's pluralism on both counts and, in the process, argues that the multiple realizability objection to reductionism is misplaced. It also argues that the Nagel model correctly characterizes reduction as a type of explanation. However, it notes that logical deduction must be replaced by a broader class of inferential techniques that allow for different types of approximation. Whereas Nagel (1970), in contrast to his earlier position (1961), recognized the relevance of approximation, he did not realize its full import for the model. Throughout the paper two case studies are used to illustrate the arguments: the putative reduction of classical thermodynamics to the kinetic theory of matter and that of classical genetics to molecular biology. (shrink)

Dans cet article, nous nous proposons de mettre en évidence deux stratégies émergentistes possibles qui constituent une médiation intéressante entre les extrêmes classiques que sont le physicalisme réductionniste et le dualisme des substances. En distinguant trois niveaux de tension possibles entre monisme et dualisme — le niveau des substances, le niveau des propriétés causales et celui des prédicats — nous sommes amené à formuler deux positions philosophiques associées à deux concepts d’émergence distincts : l’émergence représentationnelle et l’émergence causale. Ces deux (...) concepts s’avèrent fidèles aux intuitions des premiers émergentistes véhiculées au travers de l’étymologie même du concept d’émergence, et permettent une interprétation non triviale de la maxime classique : « Le tout est plus que la somme des parties. »I emphasize in this paper two possible emergentist strategies that constitute interesting middle grounds between classical views that are reductive physicalism and substance dualism. By distinguishing three levels of tension between monism and dualism — the levels of substance, causal properties and predicates — one is allowed to formulate two philosophical views that may be associated with two distinct concepts of emergence : representational emergence and causal emergence. Both concepts are faithful to the intuitions of early emergentists that are conveyed in the very etymology of the concept of emergence, and they allow a non-trivial reading of the classical maxim : “the whole is more than the sum of the parts”. (shrink)

The preference for `reductive explanations', i.e., explanations of the behaviour of a system at one `basic' level of sub-systems, seems to be related, at least in the physical sciences, to the success of a formal technique –- perturbation theory –- for extracting insight into the workings of a system from a supposedly exact but intractable mathematical description of the system. This preference for a style of explanation, however, can be justified only in the case of `regular' perturbation problems in which (...) the zeroth-order term in the perturbation expansion (characterizing the `basic' level) is the uniform limit of the exact solution as the perturbation parameter goes to zero. For the much more frequent case of `singular' perturbation problems, various techniques have been developed which all introduce a hierarchy of levels or scales into the solutions. These levels describe processes or sub-systems operating simultaneously at different time or spatial scales. No single level, no reductive explanation in the above sense will provide an adequate explanation of the system behaviour. Explanations involving multiple levels should be recognized as far more common even in supposedly reductionist disciplines like physics. (shrink)

Abstract Philosophers have paid little attention to the kind of reduction involved in transforming an analytically intractable equation into solvable form. I argue that this practice is important because it involves the design of a basic level theory for use in a specific domain. The design process can lead to the construction of a new theory. As a result of my analysis, theory design emerges as an important category of analysis for scientific methodology. Similarities between design in technology and science (...) are explored to illuminate the heuristic function of such reductions. (shrink)

Scientists employ a variety of procedures to eliminate degrees of freedom from computationally and/or analytically intractable equations. In the process, they often construct new models and discover new concepts, laws and functional relations. I argue these procedures embody a central notion of reduction, namely, the containment of one structure within another. However, their inclusion in the philosophical concept of reduction necessitates a reevaluation of many standard assumptions about the ontological, epistemological and functional features of a reduction. On the basis of (...) the reevaluation, I advocate a continuum of reduction which proceeds from the eliminative to the constructive. The metaphysical aspects of theory use in constructive reductions are sketched. (shrink)

Griffiths and Stotz’s Genetics and Philosophy: An Introduction offers a very good overview of scientific and philosophical issues raised by present-day genetics. Examining, in particular, the questions of how a “gene” should be defined and what a gene does from a causal point of view, the authors explore the different domains of the life sciences in which genetics has come to play a decisive role, from Mendelian genetics to molecular genetics, behavioural genetics, and evolution. In this review, I highlight what (...) I consider as the two main theses of the book, namely: genes are better conceived as tools; genes become causes only in a context. I situate these two theses in the wider perspective of developmental systems theory. This leads me to emphasize that Griffiths and Stotz reflect very well an on going process in genetics, which I call the “epigenetization” of genetics, i.e., the growing interest in the complex processes by which gene activation is regulated. I then make a factual objection, which is that Griffiths and Stotz have almost entirely neglected the perspective of ecological developmental biology, and more precisely recent work on developmental symbioses, and I suggest that this omission is unfortunate in so far as an examination of developmental symbioses would have considerably strengthened Griffiths and Stotz’s own conclusions. (shrink)

A mechanistic explanation is a desired outcome in many studies of perception. Such explanations require discovering the processes that contribute to the realization of a perceptual phenomenon at different levels of information processing. The present analysis aims at investigating the obstacles to develop such mechanistic explanations and their potential solutions in the context of psychopathology. Geometric-Optical Illusions (GOIs) are among perceptual phenomena that have been studied to understand psychopathology in various clinical populations. In the present analysis, the GOIs will be (...) discussed as a methodological tool in the investigation of the mechanistic approach to understanding perception in such populations. I will argue that the fact that most such studies are mainly focused on the investigation of susceptibility to GOIs can only lead to classifying such phenomena or to reporting some correlations between different aspects of such phenomena with certain brain activities, without formulating a mechanistic explanation. The investigation of the variables that mediate perceptual phenomena at earlier stages of information processing is required for the formulation of such explanations. Thus, the objective of the present analysis is twofold: 1) showing how ignoring such variables have prevented the formulation of mechanistic explanations of responses to GOIs in clinical populations, such as schizophrenia and autism, 2) analyzing the methodological aspects of an effective approach in which a top-down guidance based on phenomenological insights (the first-person data) along with the insights provided by the existing theories help overcome obstacles in developing mechanistic explanations of GOIs. (shrink)

ZusammenfassungNicht erst seit Ruth Macklins einflussreichem Aufsatz „Dignity is a useless concept“ ist eine breite Debatte um Sinn und Unsinn des Begriffs der Menschenwürde in der Medizinethik entbrannt. In diesem Beitrag möchte ich mein Augenmerk auf die von Macklin prominent gemachte Substitutionsthese richten. In ihrer einflussreich gewordenen Fassung propagiert diese eine Ersetzung des Menschenwürdebegriffs durch denjenigen der Autonomie. Doch was ist damit genau gemeint? – Ausgehend von einer Analyse von Macklins Argumenten möchte ich zeigen, unter welchen Bedingungen die Substitutionsthese die (...) von ihren Vertretern häufig in den Vordergrund gestellten eleminativen Ergebnisse zeitigt – die Rede von einem eigenständigen begrifflichen Gehalt von „Würde“ sollte aufgegeben werden. Im Verlauf der Untersuchung werden auch die Vorzüge einer solchen Position gegenüber stärker eliminativ auftretenden Standpunkten und Positionen deutlich, die den Ausdruck als berechtigt, aber unanalysierbar betrachten. (shrink)

Nicht erst seit Ruth Macklins einflussreichem Aufsatz „Dignity is a useless concept“ ist eine breite Debatte um Sinn und Unsinn des Begriffs der Menschenwürde in der Medizinethik entbrannt. In diesem Beitrag möchte ich mein Augenmerk auf die von Macklin prominent gemachte Substitutionsthese richten. In ihrer einflussreich gewordenen Fassung propagiert diese eine Ersetzung des Menschenwürdebegriffs durch denjenigen der Autonomie. Doch was ist damit genau gemeint? – Ausgehend von einer Analyse von Macklins Argumenten möchte ich zeigen, unter welchen Bedingungen die Substitutionsthese die (...) von ihren Vertretern häufig in den Vordergrund gestellten eleminativen Ergebnisse zeitigt – die Rede von einem eigenständigen begrifflichen Gehalt von „Würde“ sollte aufgegeben werden. Im Verlauf der Untersuchung werden auch die Vorzüge einer solchen Position gegenüber stärker eliminativ auftretenden Standpunkten und Positionen deutlich, die den Ausdruck als berechtigt, aber unanalysierbar betrachten. (shrink)

This paper first queries what type of concept of emergence, if any, could be connected with the different chemical activities subsumed under the label ‘quantum chemistry’. In line with Roald Hoffmann, we propose a ‘rotation to research laboratory’ in order to point out how practitioners hold a molecular whole, its parts, and the surroundings together within their various methods when exploring chemical transformation. We then identify some requisite contents that a concept of emergence must incorporate in order to be coherent (...) from the standpoint of the scientific practices involved. In this respect, we finally propose a relational form of emergence which pays attention to the constitutive role of the modes of intervention and to the co-definition of the levels of organization. No metaphysical distinction between the higher and basic levels of organization is supposed, but only a plurality of modes of access. Moreover, these modes of access are not construed as mere ways of revealing intrinsic patterns of organization but, on the contrary, are considered to be active elements on which the constitution of those patterns depends. What is at stake in this paper is therefore not an ontological form of emergence but an agnostic one which fits what chemists do in their daily work. (shrink)

Some problems rarely discussed in traditional philosophy of science are mentioned: The empirical sciences using mathematico-quantitative theoretical models are frequently confronted with several types of computational problems posing primarily methodological limitations on explanatory and prognostic matters. Such limitations may arise from the appearances of deterministic chaos and high computational complexity in general. In many cases, however, scientists circumvent such limitations by utilizing reductional approximations or complexity reductions for intractable problem formulations, thus constructing new models which are computationally tractable. Such activities (...) are compared with reduction types established in philosophy of science. (shrink)

The author draws on arguments from contemporary philosophy of mind to provide an argument for sociological collectivism. This argument for nonreductive individualism accepts that only individuals exist but rejects methodological individualism. In Part I, the author presents the argument for nonreductive individualism by working through the implications of supervenience, multiple realizability, and wild disjunction in some detail. In Part II, he extends the argument to provide a defense for social causal laws, and this account of social causation does not require (...) any commitment to intentionality or agency on the part of individuals. (shrink)

I argue that there are two distinct approaches to understanding reduction: the ontology-first approach and the theory-first approach. They concern the relation between ontological reduction and inter-theoretic reduction. Further, I argue for the significance of this distinction by demonstrating that either one or the other approach has been taken as an implicit assumption in, and has in fact shaped, our understanding of what statistical mechanics is. More specifically, I argue that the Boltzmannian framework of statistical mechanics assumes and relies on (...) the ontology-first approach, whereas the Gibbsian framework should assume the theory-first approach. -/- . (shrink)

We present two case studies from contemporary biology in which we observe conflicts between established and emerging approaches. The first case study discusses the relation between molecular biology and systems biology regarding the explanation of cellular processes, while the second deals with phylogenetic systematics and the challenge posed by recent network approaches to established ideas of evolutionary processes. We show that the emergence of new fields is in both cases driven by the development of high-throughput data generation technologies and the (...) transfer of modeling techniques from other fields. New and emerging views are characterized by different philosophies of nature, i.e. by different ontological and methodological assumptions and epistemic values and virtues. This results in a kind of conflict we call “epistemic competition” that manifests in two ways: On the one hand, opponents engage in mutual critique and defense of their fundamental assumptions. On the other hand, they compete for the acceptance and integration of the knowledge they provide by a broader scientific community. Despite an initial rhetoric of replacement, the views as well as the respective audiences come to be seen as more clearly distinct during the course of the debate. Hence, we observe—contrary to many other accounts of scientific change—that conflict results in the formation of new niches of research, leading to co-existence and perceived complementarity of approaches. Our model thus contributes to the understanding of the pluralization of the scientific landscape. (shrink)

Kenneth C. Schaffner's paper is an important contribution to the literature on behavioral genetics and on genetics in general. Schaffner has a long record of injecting real molecular biology into philosophical discussions of genetics. His treatments of the reduction of Mendelian to molecular genetics first drew philosophical attention to the problems of detail that have fuelled both anti-reductionism and more sophisticated models of theory reduction. An injection of molecular detail into discussions of genetics is particularly necessary at the present time, (...) when so many philosophers seem happy to discuss the philosophical and ethical implications of molecular biology using gene concepts derived from evolutionary biology ). Schaffner has long advocated the view that the philosophy of biology should be more than the philosophy of evolution. This paper shows how radically a picture of gene action derived from molecular biology undercuts the popular picture associated with a more evolutionary view of genes as units of heredity or as ‘difference-makers’ mediated by the ‘black box’ of development. (shrink)

This article is devoted to the conceptual analysis of two texts of leading scholars in cognitive neuroscience and its philosophy, Patricia Churchland and Eric Kandel. After a short introduction about the notion of reduction, I give a detailed account of the way both scientists view the relationship between theories about brain functioning on the one hand and consciousness and psychopathology, respectively, on the other hand. The analysis not only reveals underlying philosophical mind/brain conceptions and their inner tensions, but also the (...) conceptual relevance of distinctions that are fundamental in the work of Dooyeweerd, such as the distinction between modes and entities, between law and subject and between subject function and object function. After a brief clarification of the way these distinctions function in Dooyeweerd’s theory of the body as an ‘enkaptic structural whole’, I try to explain how the conceptual framework, developed here, could be applied to brain functioning and leads to greater clarity in neuroscientific theorizing. (shrink)

Recently the functional model of reduction has become something like the standard model of reduction in philosophy of mind. In this paper, I argue that the functional model fails as an account of reduction due to problems related to three key concepts: functionalization, realization and causation. I further argue that if we try to revise the model in order to make it more coherent and scientifically plausible, the result is merely a simplified version of what in philosophy of science is (...) known as mechanistic explanation. Hence, instead of analyzing reduction in philosophy of mind in terms of functional reduction, it should be analyzed in terms of mechanistic explanation. (shrink)

The reductionist/holist debate seems an impoverished one, with many participants appearing to adopt a position first and constructing rationalisations second. Here I propose an intermediate position of pragmatic holism, that irrespective of whether all natural systems are theoretically reducible, for many systems it is completely impractical to attempt such a reduction, also that regardless if whether irreducible `wholes' exist, it is vain to try and prove this in absolute terms. This position thus illuminates the debate along new pragmatic lines, and (...) refocusses attention on the underlying heuristics of learning about the natural world. (shrink)

All suggested notions of reduction of two scientific theories are critically reviewed and analyzed. In particular those applied to the case of the alleged reduction of Chemistry to Quantum mechanics are examined. Since it is recognized that the weakness of this field of research is the lack of a definition of a scientific theory, it is suggested that a scientific theory is characterized by two choices regarding two dichotomies, that is, the kind of mathematics and the kind of logic. According (...) to this view a reduction is only possible between two theories in which the same choices are shared. As a consequence, only one case of reduction in the history of physics is recognized: physical optics to electromagnetism, a case that is commonly accepted. The other cases of claimed reductions are recognized as impossible, owing to the different choices of the two theories at issue and hence the radical variations in meaning of their shared basic notions. In particular, the claimed reduction of Chemistry to Quantum mechanics is disproved in detail. (shrink)

Convincing disputes about explanatory reductionism in the philosophy of biology require a clear and precise understanding of what a reductive explanation in biology is. The central aim of this book is to provide such an account by revealing the features that determine the reductive character of a biological explanation. Chapters I-IV provide the ground, on which I can then, in Chapter V, develop my own account of explanatory reduction in biology: Chapter I reveals the meta-philosophical assumptions that underlie my analysis (...) of reduction, Chapter II introduces the previous debate about reduction in the philosophy of biology by pointing out the most crucial lessons one should learn from this debate, Chapter III critically discusses the two perspectives on explanatory reduction that have been proposed in the philosophy of biology so far, and Chapter IV clarifies in what ways the issue of reduction is entangled with the issue of explanation. In Chapter V I present my own account of explanatory reduction. My main claim is that reductive explanations in the biological sciences possess three main characteristics: they explain the behavior of a biological system S, first, exclusively in terms of factors that are located on a lower level of organization than S, second, by focusing on factors that are internal to S , and third, by describing the genuine parts of S only as “parts in isolation”. This account is ontic because it traces the reductivity of an explanation back to certain relations that exist in the world. (shrink)