This is a response to Earp and colleagues' target article "If I could just stop loving you: Anti-love biotechnology and the ethics of a chemical break-up". I argue that the authors may indulge in the vice of in-principlism when presenting their ethical framework for dealing with anti-love biotechnology, and that they mis-apply the concept of harm.

The growth of self-tracking and personal surveillance has given rise to the Quantified Self movement. Members of this movement seek to enhance their personal well-being, productivity, and self-actualization through the tracking and gamification of personal data. The technologies that make this possible can also track and gamify aspects of our interpersonal, romantic relationships. Several authors have begun to challenge the ethical and normative implications of this development. In this article, we build upon this work to provide a detailed ethical analysis (...) of the Quantified Relationship. We identify eight core objections to the QR and subject them to critical scrutiny. We argue that although critics raise legitimate concerns, there are ways in which tracking technologies can be used to support and facilitate good relationships. We thus adopt a stance of cautious openness toward this technology and advocate the development of a research agenda for the positive use of QR technologies. (shrink)

Personal AI assistants are now nearly ubiquitous. Every leading smartphone operating system comes with a personal AI assistant that promises to help you with basic cognitive tasks: searching, planning, messaging, scheduling and so on. Usage of such devices is effectively a form of algorithmic outsourcing: getting a smart algorithm to do something on your behalf. Many have expressed concerns about this algorithmic outsourcing. They claim that it is dehumanising, leads to cognitive degeneration, and robs us of our freedom and autonomy. (...) Some people have a more subtle view, arguing that it is problematic in those cases where its use may degrade important interpersonal virtues. In this article, I assess these objections to the use of AI assistants. I will argue that the ethics of their use is complex. There are no quick fixes or knockdown objections to the practice, but there are some legitimate concerns. By carefully analysing and evaluating the objections that have been lodged to date, we can begin to articulate an ethics of personal AI use that navigates those concerns. In the process, we can locate some paradoxes in our thinking about outsourcing and technological dependence, and we can think more clearly about what it means to live a good life in the age of smart machines. (shrink)

Wilkinson and Savulescu did not agree with the court's decision to continue M's treatment and suggested in their recent commentary that the magnitude of benefits of being alive for M is small compared with the potential use of health resources for other patients. We argue that the benefits of being sensate to the surroundings for an otherwise unconscious person are not necessarily small. One cannot assess on behalf of another person the magnitude of benefits of being alive according to the (...) intensity or the duration of negative experiences. Denying life-sustaining treatment to patients in a minimally conscious state solely on the grounds that they are less capable of enjoying the benefits represents grave discrimination against disabled persons. For patients in a minimally conscious state who have not delegated a surrogate or made any advance decision about their medical treatment, the duty of doctors is to preserve their right to self-determination and maximise their capacity to enjoy their life. M should live on, and life-sustaining treatment should not be withdrawn. (shrink)

The Principle of Procreative Beneficence (PB) holds that when a couple plans to have a child, they have significant moral reason to select, of the possible children they could have, the child who is most likely to experience the greatest wellbeing – that is, the most advantaged child, the child with the best chance at the best life.1 PB captures the common sense intuitions of many about reproductive decisions. PB does not posit an absolute moral obligation – it does not (...) dictate what people must do. Instead it holds that there is a significant moral reason to select the best child, but one that must be weighed against other reasons.Recent research suggests that it may become possible to derive gametes (eggs and sperm) from human stem cells in vitro, a process which we will term in vitro gametogenesis (IVG). The ability to create large numbers of eggs or sperm through IVG greatly increases our capacity to select the best child possible. (shrink)

Applies a generally Thomistic framework to Earp and colleagues' (2013) discussion of anti-love biotechnology. Discusses some of the constraints that should be placed on the use of such a technology from a Thomistic perspective.

This paper explores the scriptural and theological reasons given by Jehovah's Witnesses (JWs) to refuse blood transfusions. Julian Savulescu and Richard W Momeyer argue that informed consent should be based on rational beliefs and that the refusal of blood transfusions by JWs is irrational, but after examining the reasons given by JWs, I challenge the claim that JW beliefs are irrational. I also question whether we should give up the traditional notion of informed consent.

Este trabajo se plantea tres cuestiones dirigidas a mejorar las propuestas sobre la gobernanza y regulación de la biología sintética. En primer lugar, se refieren algunos de los hitos científicos que han jalonado su desarrollo y el modo en que han influido en los debates ciudadanos sobre ella. En segundo lugar, se trata del marco jurídico internacional, con el fin de indagar en los principios sobre los que se sustenta y debería sustentarse. Por último, se revisan críticamente los informes acerca (...) de los aspectos éticos y sociales de la BIOSIN, publicados por organizaciones gubernamentales y no gubernamentales en los últimos diez años. (shrink)

Purposeful infection of healthy volunteers with a microbial pathogen seems at odds with acceptable ethical standards, but is an important contemporary research avenue used to study infectious diseases and their treatments. Generally termed ‘controlled human infection studies’, this research is particularly useful for fast tracking the development of candidate vaccines and may provide unique insight into disease pathogenesis otherwise unavailable. However, scarce bioethical literature is currently available to assist researchers and research ethics committees in negotiating the distinct issues raised by (...) research involving purposefully infecting healthy volunteers. In this article, we present two separate challenge studies and highlight the ethical issues of human challenge studies as seen through a well-constructed framework. Beyond the same stringent ethical standards seen in other areas of medical research, we conclude that human challenge studies should also include: independent expert reviews, including systematic reviews; a publicly available rationale for the research; implementation of measures to protect the public from spread of infection beyond the research setting; and a new system for compensation for harm. We hope these additions may encourage safer and more ethical research practice and help to safeguard public confidence in this vital research alternative in years to come. (shrink)

No filme Gattaca, imagina-se um futuro já nada distante em que os casais poderão consultar um especialista em fertilização artificial e escolher as características de seu futuro filho. Eles podem selecionar embriões fertilizados em laboratório, podendo também alterar seus traços genéticos, eliminando genes capazes de expressar doenças ou mesmo características físicas indesejáveis. Técnicas recentes, como a edição genética por Prime Editing ou por meio da CRISPR-Cas9, logo permitirão terapias gênicas em embriões fertilizados in vitro antes de sua implantação uterina. Neste (...) artigo, pretendemos avaliar essas possibilidades, revisando criticamente alguns argumentos conhecidos contra o uso indiscriminado de tais técnicas. Ao final, em defesa de que objeções de princípio a práticas eugênicas devem estar assentadas na proteção e promoção dos direitos humanos, pretendemos avaliar quais limites poderiam publicamente justificar a permissão ou proibição do uso privado de tais técnicas. (shrink)

Recent rapid technological and medical advance has more than ever before brought to the fore a spectrum of problems broadly categorized under the umbrella of ‘ethics of human enhancement’. Some of the most contentious issues are typified well by the arguments put forward in a recent article on human cognitive enhancement authored by Garasic and Lavazza. Herein I analyse some of the assumptions made in their work and highlight important flaws. In particular I address the problems associated with the distinction (...) between ‘treatment’ and ‘enhancement’, and ‘natural’ vs. ‘non-natural’ therapies. (shrink)

The debate between Ursin (2019) and Wilkinson and colleagues (2019) in this issue of The American Journal of Bioethics underscores the long-standing theoretical controversy about the equivalence of...

Engineering an artificial intelligence to play an advisory role in morally charged decision making will inevitably introduce meta-ethical positions into the design. Some of these positions, by informing the design and operation of the AI, will introduce risks. This paper offers an analysis of these potential risks along the realism/anti-realism dimension in metaethics and reveals that realism poses greater risks, but, on the other hand, anti-realism undermines the motivation for engineering a moral AI in the first place.

No artigo, abordo a ideia de melhoramento humano (MH), visando a contestar três frustrantes tendências dos seus críticos, a saber, as ideias de: (1) que a natureza humana será artificializada, sugerindo que estaremos diante de algo novo e incomparavelmente perigoso, bem como que ainda seja possível preservar uma separação radical entre natureza e técnica; (2) que é possível abordar e criticar o MH a partir de uma singularidade semântica; e, diretamente relacionada à anterior, (3) que há univocidade entre os defensores (...) do MH acerca de como os indivíduos devem lidar com os meios biotecnocientíficos disponibilizados, a saber, como uma ingênua e acrítica obrigação de melhorar. In this paper, I discuss the idea of human enhancement (HE). My goal is to refute three frustrating trends in the HE criticism, namely the ideas that: (1) human nature will become artificial, suggesting that we will be facing something new and uniquely dangerous, and that it is still possible to preserve a radical separation between nature and technique; (2) it is possible to address and criticize HE from a semantic uniqueness, which is directly related to the previous item; and (3) there is an univocity among the HE's defenders on how individuals should handle the available bio-techno-scientific tools made available, namely, as a naive and uncritical obligation to become enhanced. (shrink)

Imagine a world where everyone is healthy, intelligent, long living and happy. Intuitively this seems wonderful albeit unrealistic. However, recent scienti c breakthroughs in genetic engineering, namely CRISPR/Cas bring the question into public discourse, how the genetic enhancement of humans should be evaluated morally. In 2001, when preimplantation genetic diagnosis (PGD) and in vitro fertilisation (IVF), enabled parents to select between multiple embryos, Julian Savulescu introduced the principle of procreative bene cence (PPB), stating that parents have the obligations to choose (...) the child that is expected to have the best life. In this paper I argue that accepting the PPB and the consequentialist principle (CP) that two acts with the same consequences are morally on par, commits one to accepting the parental obligation of genetically enhancing one's children. (shrink)

The invasion of the new technologies in our lives and the current dependence upon them makes us believe that in a not too distant future we will be made of more technology than biological matter. If until recently computers had hardly been discovered, today we are witnessing a real technological revolution in all the fields: biology, medicine etc. The evolution of the new technologies has raised various questions related to the future of mankind and the current human species, which determines (...) us to make speculations regarding a future event that may occur. For this reason, in this paper I shall analyze the concept of artificial intelligence and singularity and I shall also outline the relationship between the ontological argument and the possible worlds. The idea of possible world can serve as a way of describing a metaphor in the philosophy of science, as singularity can exist in a possible world only if one creates the conditions of a new concept regarding fiction. We believe that technological singularity will change the values of the current society and the individual will have to face a world that depersonalizes the individual, as transhumanism draws the theoretical frameworks of a ‹‹brave new world››. In this paper, we have also analyzed the logical explanation of God's existence and the explanation of singularity through artificial intelligence. Therefore, we shall bring up for discussion the idea of virtual universe in the context of downloaded consciousness, which can be operated through artificial intelligence. Our conclusions refer to the fact that eternal life could exist artificially, but it cannot be demonstrated in terms of the ontological argument. (shrink)

By using tissue typing in conjunction with preimplantation genetic diagnosis doctors are able to pick a human embryo for implantation which, if all goes well, will become a “saviour sibling”, a brother or sister capable of donating life-saving tissue to an existing child.This paper addresses the question of whether this form of selection should be banned and concludes that it should not. Three main prohibitionist arguments are considered and found wanting: the claim that saviour siblings would be treated as commodities; (...) a slippery slope argument, which suggests that this practice will lead to the creation of so-called “designer babies”; and a child welfare argument, according to which saviour siblings will be physically and/or psychologically harmed. (shrink)

While philosophers are often concerned with the conditions for moral knowledge or justification, in practice something arguably less demanding is just as, if not more, important – reliably making correct moral judgments. Judges and juries should hand down fair sentences, government officials should decide on just laws, members of ethics committees should make sound recommendations, and so on. We want such agents, more often than not and as often as possible, to make the right decisions. The purpose of this paper (...) is to propose a method of enhancing the moral reliability of such agents. In particular, we advocate for a procedural approach; certain internal processes generally contribute to people’s moral reliability. Building on the early work of Rawls, we identify several particular factors related to moral reasoning that are specific enough to be the target of practical intervention: logical competence, conceptual understanding, empirical competence, openness, empathy and bias. Improving on these processes can in turn make people more morally reliable in a variety of contexts and has implications for recent debates over moral enhancement. (shrink)

Bioethicists and philosophers dominate the on-going debate on human enhancement. They have debated the definition of human enhancement as well as the potential impacts of human enhancement technologies (such as pharmaceutical enhancements or pre-natal selection). These discussions have percolated, through bioethics bodies and bioethics recommendations, policy makers and have eventually been translated into policy. While some suggestions have been based largely in Western liberal democracies, others have deliberated the geopolitical consequences of human enhancement technologies. This paper argues that the present (...) debate currently lacks perspectives from developing countries. It begins by introducing the current debate on human enhancement and recognizes Allen Buchanan’s well-raised concerns on how these technologies may potentially cause new injustices for low- and middle-income countries (‘developing countries’). It then provides two arguments calling for further research into human enhancement from the perspective of developing countries. First, this paper will argue that the current frames with which enhancement technologies are viewed are inherently neoliberal and require change. The second argument shows how the potential impacts of human enhancement technologies in developing countries have not been fully realized by analyzing how human enhancement technologies will impact Thailand, a developing country. (shrink)

Current general restrictions on performance-enhancing drugs pose a collective action problem that cannot be solved and bring a variety of adverse consequences for sport. General prohibitions of PEDs are grounded in claims that they violate the integrity of sport. But there are decisive arguments against integrity of sport-based prohibitions of PEDs for elite sport. We defend a harm prevention approach to PED prohibition as an alternative. This position cannot support a general ban on PEDs, since it provides no basis for (...) prohibiting non-harmful PED use. We argue that a harm prevention approach to restricting PEDs is ethically justified, has better prospects of compliance, is consistent with respecting the integrity of sport, and holds at least a modest prospect of resolving the collective action problem around PED restriction. (shrink)

‘Liberal eugenics’ has emerged as the most popular position amongst philosophers writing in the contemporary debate about the ethics of human enhancement. This position has been most clearly articulated by Nicholas Agar, who argues that the ‘new’ liberal eugenics can avoid the repugnant consequences associated with eugenics in the past. Agar suggests that parents should be free to make only those interventions into the genetics of their children that will benefit them no matter what way of life they grow up (...) to endorse. I argue that Agar's attempt to distinguish the new from the old eugenics fails. Once we start to consciously determine the genetics of future persons, we will not be able to avoid controversial assumptions about the relative worth of different life plans. Liberal eugenicists therefore confront the horns of a dilemma. Whichever way they try to resolve it, the consequences of widespread use of technologies of genetic selection are likely to look more like the old eugenics than defenders of the new eugenics have acknowledged. (shrink)

When denial of medical treatment is being used as a lever to move people out of the country, ethicists and healthcare professionals should speak out.An ugly feature of political life throughout the Western world, and beyond, is the suspicion towards, and maltreatment of, migrants from poor to rich countries. People who would otherwise be horrified at being labelled racist nevertheless find it acceptable to support practices which can range from stigmatisation to confinement in brutalising conditions in “reception” and “removal” centres.1–5An (...) hour spent searching through government and NGO websites concerned with the treatment of asylum seekers and refugees in developed world countries is an hour well spent – but profoundly depressing. This is not only because of the frankly Orwellian language used by the governments of the UK and Australia , or because of the conditions and treatment meted out, but also because of the apparent support these practices have among the voting public. In the pointedly optimistic reports of Her Majesty’s Inspector of Prisons, for example, one can find praise for the fact …. (shrink)

In his challenging paper,1 Vojin Rakic argues against our claim that ‘there are strong reasons to believe’ that moral bioenhancement should be obligatory or compulsory if it can be made safe and effective.2 Rakic starts by criticising an argument that we employed against John Harris.3 ,4 In this argument we maintain, among other things, that moral bioenhancement cannot be wholly effective if our will is free in what is called an ‘indeterministic’ or ‘contra-causal sense’; that is, if our choices are (...) not fully determined by our biology and environmental circumstances. Rakic contends that we ‘do not take into account the possibility that we can have an entirely free will that does not limit the effectiveness of moral bio-enhancement’. We can use ‘our freedom to decide to be morally bio-enhanced’.In reply, we would like to insist that if our freedom is freedom in this indeterministic sense, we cannot use this freedom to decide to subject ourselves to effective moral bioenhancement, since this effectiveness presupposes that our will is fully determined by biological causes that this enhancement influences. If certain sub-atomic processes are indeterministic, probabilistic, we cannot make them deterministic. We cannot change the laws …. (shrink)

Para encontrar el lugar de la tecnología en la vida humana es preciso preguntarse qué es la tecnología y cuál es su relación con el hombre. Tres nociones resultan decisivas para responder a estas preguntas: una concepción de la naturaleza que sirva como criterio normativo de la acción, tal como la comprendieron los griegos, una visión positiva de la producción y la comprensión del hombre como ser personal.

Conceiving a child by way of embryo selection and tissue matching to benefit a sick sibling is generally justified on the grounds that as well as the potential to save the sick child, there is a benefit for the new baby. The new baby is selected so he or she will not have the disease suffered by the first child. It is not possible, however, to select against conditions for which there is no test and Jamie Whitaker’s birth is a (...) case where the process of in vitro fertilisation with tissue matching is viewed as being of benefit only to a third party—the sick child. Some people object to using the technology for this purpose. There are also good reasons to argue that the technology should be used to save a sick child, and that it would be morally remiss for Jamie’s parents not to consent to the use of his cord blood. (shrink)

Since human reproduction is arguably both irrational and immoral, those who seek help before conceiving could be advised it is all right not to have children.

Preimplantation genetic diagnosis—the risks are unknown and human dignity could be compromisedMerle Spriggs argues that there are no good reasons to prevent a couple utilising preimplantation genetic diagnosis when the sole aim of the procedure is that the resultant child is a compatible umbilical cord blood donor for a sick sibling.1 I agree with much of the argument to support this, however, I believe Spriggs has omitted one important point and underplayed another.The risk of PGD to the child born as (...) a result of this process has not been fully studied. Therefore the parents are exposing the child to potential …. (shrink)

Davis called for “extreme caution” in the use of non-invasive brain stimulation to treat neurological disorders in children, due to gaps in scientific knowledge. We are sympathetic to his position. However, we must also address the ethical implications of applying this technology to minors. Compensatory trade-offs associated with NIBS present a challenge to its use in children, insofar as these trade-offs have the effect of limiting the child’s future options. The distinction between treatment and enhancement has some normative force here. (...) As the intervention moves away from being a treatment toward being an enhancement—and thus toward a more uncertain weighing of the benefits, risks, and costs—considerations of the child’s best interests diminish, and the need to protect the child’s autonomy looms larger. NIBS for enhancement involving trade-offs should therefore be delayed, if possible, until the child reaches a state of maturity and can make an informed, personal decision. NIBS for treatment, by contrast, is permissible insofar as it can be shown to be at least as safe and effective as currently approved treatments, which are themselves justified on a best interests standard. (shrink)

Para entrever el futuro de la bioética lo primero que tenemos que pensar es la propia noción de futuro y nuestra relación práctica con el mismo. Expongo aquí a la crítica la idea de un futuro que esté ya de algún modo presente y a la vista. Es esta una idea que desposee al futuro de toda futureidad, una idea, por lo tanto, incoherente. Propongo, a cambio, pensar el futuro como tarea, como agenda, como aquello que no está y ha (...) de ser libremente hecho. En este sentido, resulta inútil tratar de vislumbrar o adivinar el futuro de la bioética, y en cambio es preciso proponernos como tarea la creación de la bioética futura. Vistas así las cosas, la función principal de la bioética no será ya la de deliberar y elegir entre las opciones que se nos presentan, sino la de crear nuevos cursos de acción que protejan y favorezcan mejor la vida en general y la vida humana en particular. Abogo, pues, en este texto, por una bioética de la creatividad y de la laboriosidad, superadora de la bioética de dilemas. (shrink)

El transhumanismo es una moda intelectual que propone la transformación de los seres humanos mediante diversas tecnologías. Expondremos brevemente los rasgos más conspicuos del TH, así como las principales críticas que se le han hecho. Pero la intención de este artículo no es entrar en esta polémica; aportaremos tan solo las claves imprescindibles para poder seguir adelante. Y una de las claves más intrigantes del TH es que, por debajo de su pátina tecno-futurista, remite a ciertas ideas filosóficas tan viejas (...) como, en apariencia, incompatibles entre sí. El TH remite al naturalismo radical, tanto como al nihilismo existencialista. La tesis que aquí se defiende es que tanto el naturalismo radical como el nihilismo existencialista son producto de las diversas oleadas del dualismo: del dualismo platónico antiguo, del dualismo cartesiano moderno. Una vez que separamos, a la manera dualista, la libertad por un lado y la naturaleza por el otro, podemos contar hasta dos, como hacen los dualistas, o quedarnos solo en uno, como hacen los existencialistas, que se paran en la libertad, y los naturalistas, que solo cuentan con la naturaleza. En cualquier caso, la imagen del ser humano, que es libertad y naturaleza, sale dañada. Asoma entonces el animal aporético y enfermizo al cual hay que salvar… de sí mismo. ¿Cómo? Siguiendo el método de Procusto, pero ahora con los prefijos bio e info en lugar de sierra y martillo. Hasta que el pobre ser humano encaje en el lecho de la utopía que algunos visionarios han urdido. ¿Y no hay otra vía, otra forma de mejorar la vida humana que sea más respetuosa para con la humana envergadura? Quizá sí, mas para trazar esa tercera vía, entre el naturalismo radical que mutila y el nihilismo existencialista que descoyunta y estira, habría que negar de antemano el dualismo que a los dos engendra, y atenerse a la sensatez común, en línea con la tradición aristotélica, antes que a las ensoñaciones utópicas. En nuestra opinión, el concepto aristotélico de naturaleza humana nos habilita para juzgar las antropotecnias mejor que la normatividad extraída de las visiones futuristas propias del TH. (shrink)

Uno de los debates más recientes referentes a la innovación tecnológica entre los especialistas en ética es aquel sobre la mejora humana, el cual ha surgido a raíz de la posibilidad de modificar los límites de la naturaleza humana usando el poder de la ciencia. Muchos filósofos nos han avisado del peligro de modificar técnicamente nuestra naturaleza humana. Otros, por contra, defienden que no existe diferencia moral relevante alguna entre las nuevas técnicas biomédicas de mejora y las tecnologías aceptadas como (...) habituales por los seres humanos. Este artículo pretende examinar críticamente tal argumento. El fin de este análisis crítico será doble, primero, mostrar que los autores que defienden esta posición poseen visiones sesgadas y prejuiciosas de la realidad y, segundo, que es necesario establecer una definición más precisa y acotada del término “mejora”. (shrink)

Most agree that, if all else is equal, patients should be provided with enough information about proposed medical therapies to allow them to make an informed decision about what, if anything, they wish to receive. This is the principle of informed choice; it is closely related to the notion of informed consent. Contemporary clinical trials are analysed according to classical statistics. This paper puts forward the argument that classical statistics does not provide the right sort of information for informing choice. (...) The notion of probability used by classical statistics is complex and difficult to communicate. Therapeutic decisions are best informed by statistical approaches that assign probabilities to hypotheses about the benefits and harms of therapies. Bayesian approaches to statistical inference provide such probabilities. (shrink)

The compromise position that accepts the use and derivation of stem cells from spare in vitro fertilisation embryos but opposes the creation of embryos for these purposes is a very weak ethical position. This paper argues that whatever the basis is on which defenders of this viewpoint accord intrinsic value to the embryo, once they accept the creation and sacrifice of embryos to benefit infertile people with a child-wish, they do not have a sound moral argument to condemn the creation (...) and sacrifice of embryos to benefit ill and injured people. (shrink)