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  1. Small RNA research and the scientific repertoire: a tale about biochemistry and genetics, crops and worms, development and disease.Sophie Juliane Veigl - 2021 - History and Philosophy of the Life Sciences 43 (1):1-25.
    The discovery of RNA interference in 1998 has made a lasting impact on biological research. Identifying the regulatory role of small RNAs changed the modes of molecular biological inquiry as well as biologists' understanding of genetic regulation. This article examines the early years of small RNA biology's success story. I query which factors had to come together so that small RNA research came into life in the blink of an eye. I primarily look at scientific repertoires as facilitators of rapid (...)
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  • (1 other version)Teaching Biologists the Philosophy of Their Time.Sophie Juliane Veigl - 2021 - Acta Biotheoretica 69 (3):483-491.
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  • Elusive vehicles of genetic representation.Riin Kõiv - 2020 - Biology and Philosophy 35 (1):1-24.
    The teleosemantic theory of representational content is held by some philosophers to imply that genes carry semantic information about whole-organism phenotypes. In this paper, I argue that this position is not supported by empirical findings. I focus on one of the most elaborate defenses of this position: Shea’s view that genes represent whole-organism phenotypes. I distinguish between two ways of individuating genes in contemporary biological science as possible vehicles of representational content—as molecular genes and as difference-maker genes. I show that (...)
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  • Quantitative methods in philosophy of language.Rafael Ventura - 2019 - Philosophy Compass 14 (7):e12609.
    In this paper, I survey and defend the use of quantitative methods in philosophy of language. Quantitative methods in philosophy of language include a wide variety of methods, ranging from model‐based techniques (computer simulations and mathematical models) to data‐driven approaches (experimental philosophy and corpus‐based studies). After offering a few case studies of these methodologies in action, I single out some debates in philosophy of language that are especially well served by their use. These are cases in which quantitative methods increase (...)
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  • Why Causal Evidencing of Risk Fails. An Example from Oil Contamination.Elena Rocca & Rani Lill Anjum - 2019 - Ethics, Policy and Environment 22 (2):197-213.
    ABSTRACTMeasurements of environmental toxicity from long-term exposure to oil contamination have delivered inaccurate and contradictory results regarding the potential harms for humans and ecosyste...
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  • Scientists’ attitudes on science and values: Case studies and survey methods in philosophy of science.Daniel Steel, Chad Gonnerman & Michael O'Rourke - 2017 - Studies in History and Philosophy of Science Part A 63:22-30.
    This article examines the relevance of survey data of scientists’ attitudes about science and values to case studies in philosophy of science. We describe two methodological challenges confronting such case studies: 1) small samples, and 2) potential for bias in selection, emphasis, and interpretation. Examples are given to illustrate that these challenges can arise for case studies in the science and values literature. We propose that these challenges can be mitigated through an approach in which case studies and survey methods (...)
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  • Philosophical analyses of scientific concepts: A critical appraisal.Daniel Mark Kraemer - 2018 - Philosophy Compass 13 (9):e12513.
    Philosophical analyses of scientific concepts are legion. However, this literature is replete with methodological errors that have largely gone unnoticed. Five distinct projects are conflated which has led to faulty inferences, ambiguities, and mischaracterizations. There has also been some recent enthusiasm for approaches that attempt to rectify problematic scientific concepts but the motivations for these approaches are questionable. I am hopeful that by bringing these various issues to light that it will lead practitioners to be more explicit about their aims (...)
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  • Ni cabalmente clásico, ni completamente molecular: un análisis del concepto de gen en la genética del comportamiento.Nahuel Pallitto & Guillermo Folguera - 2017 - Scientiae Studia 15 (2):439.
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  • Conceptual Variation or Incoherence? Textbook Discourse on Genes in Six Countries.Niklas M. Gericke, Mariana Hagberg, Vanessa Carvalho dos Santos, Leyla Mariane Joaquim & Charbel N. El-Hani - 2014 - Science & Education 23 (2):381-416.
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  • Jane Addams as experimental philosopher.Joshua August Skorburg - 2018 - British Journal for the History of Philosophy 26 (5):918-938.
    This paper argues that the activist, feminist and pragmatist Jane Addams was an experimental philosopher. To defend this claim, I argue for capacious notions of both philosophical pragmatism and experimental philosophy. I begin in Section 2 with a new defence of Rose and Danks’ [‘In Defense of a Broad Conception of Experimental Philosophy’. Metaphilosophy 44, no. 4 : 512–32] argument in favour of a broad conception of experimental philosophy. Koopman [‘Pragmatist Resources for Experimental Philosophy: Inquiry in Place of Intuition’. Journal (...)
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  • LIS and BCIs: a Local, Pluralist, and Pragmatist Approach to 4E Cognition.Ruth Hibbert - 2016 - Neuroethics 9 (2):187-198.
    Four previous papers in this journal have discussed the role of Brain-Computer Interfaces in the lives of Locked-In Syndrome patients in terms of the four “E” frameworks for cognition – extended, embedded, embodied, and enactive cognition. This paper argues that in the light of more recent literature on these 4E frameworks, none of the four papers has taken quite the right approach to deciding which, if any, of the E frameworks is the best one for the job. More specifically, I (...)
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  • History in the Gene: Negotiations Between Molecular and Organismal Anthropology.Marianne Sommer - 2008 - Journal of the History of Biology 41 (3):473-528.
    In the advertising discourse of human genetic database projects, of genetic ancestry tracing companies, and in popular books on anthropological genetics, what I refer to as the anthropological gene and genome appear as documents of human history, by far surpassing the written record and oral history in scope and accuracy as archives of our past. How did macromolecules become "documents of human evolutionary history"? Historically, molecular anthropology, a term introduced by Emile Zuckerkandl in 1962 to characterize the study of primate (...)
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  • Is it Time for an Updated ‘Eco-Evo-Devo’ Definition of Evolution by Natural Selection?Marion Blute - 2008 - Spontaneous Generations 2 (1):1.
    Abstract A lot of science has passed under the bridge since the classic definition of evolution as a change in gene frequencies in a population became common. Much knowledge has accumulated since then about evolution, heredity, ecology, development, phenotypic plasticity, niche construction and genetic drift. Building on Van Valen’s description of evolution as “the control of development by ecology,” it is suggested that the classic definition be replaced by a updated ‘eco‐evo-evo’ definition of evolution by natural selection which acknowledges this (...)
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  • Scientific Classification.John Dupré - 2006 - Theory, Culture and Society 23 (2-3):30-32.
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  • Environmental Ethics.Roberta L. Millstein - 2013 - In Kostas Kampourakis (ed.), The Philosophy of Biology: a Companion for Educators. Dordrecht: Springer.
    A number of areas of biology raise questions about what is of value in the natural environment and how we ought to behave towards it: conservation biology, environmental science, and ecology, to name a few. Based on my experience teaching students from these and similar majors, I argue that the field of environmental ethics has much to teach these students. They come to me with pent-up questions and a feeling that more is needed to fully engage in their subjects, and (...)
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  • Artificial Language Philosophy of Science.Sebastian Lutz - 2011 - European Journal for Philosophy of Science 2 (2):181–203.
    Abstract Artificial language philosophy (also called ‘ideal language philosophy’) is the position that philosophical problems are best solved or dissolved through a reform of language. Its underlying methodology—the development of languages for specific purposes—leads to a conventionalist view of language in general and of concepts in particular. I argue that many philosophical practices can be reinterpreted as applications of artificial language philosophy. In addition, many factually occurring interrelations between the sciences and philosophy of science are justified and clarified by the (...)
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  • Remembering (Short-Term) Memory: Oscillations of an Epistemic Thing.Uljana Feest - 2011 - Erkenntnis 75 (3):391-411.
    This paper provides an interpretation of Hans-Jörg Rheinberger’s notions of epistemic things and historical epistemology . I argue that Rheinberger’s approach articulates a unique contribution to current debates about integrated HPS, and I propose some modifications and extensions of this contribution. Drawing on examples from memory research, I show that Rheinberger is right to highlight a particular feature of many objects of empirical research (“epistemic things”)—especially in the contexts of exploratory experimentation—namely our lack of knowledge about them. I argue that (...)
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  • Why the (gene) counting argument fails in the massive modularity debate: The need for understanding gene concepts and genotype-phenotype relationships.Kathryn S. Plaisance, Thomas A. C. Reydon & Mehmet Elgin - 2012 - Philosophical Psychology 25 (6):873-892.
    A number of debates in philosophy of biology and psychology, as well as in their respective sciences, hinge on particular views about the relationship between genotypes and phenotypes. One such view is that the genotype-phenotype relationship is relatively straightforward, in the sense that a genome contains the ?genes for? the various traits that an organism exhibits. This leads to the assumption that if a particular set of traits is posited to be present in an organism, there must be a corresponding (...)
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  • Philosophy and default descriptivism: The functions debate.Björn Brunnander - 2011 - Metaphilosophy 42 (4):417-430.
    Abstract: By focusing on contributions to the literature on function ascription, this article seeks to illustrate two problems with philosophical accounts that are presented as having descriptive aims. There is a motivational problem in that there is frequently no good reason why descriptive aims should be important, and there is a methodological problem in that the methods employed frequently fail to match the task description. This suggests that the task description as such may be the result of “default descriptivism,” a (...)
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  • The Study of Socioethical Issues in Systems Biology.Maureen A. O'Malley, Jane Calvert & John Dupré - 2007 - American Journal of Bioethics 7 (4):67-78.
    Systems biology is the rapidly growing and heavily funded successor science to genomics. Its mission is to integrate extensive bodies of molecular data into a detailed mathematical understanding of all life processes, with an ultimate view to their prediction and control. Despite its high profile and widespread practice, there has so far been almost no bioethical attention paid to systems biology and its potential social consequences. We outline some of systems biology's most important socioethical issues by contrasting the concept of (...)
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  • Innateness as Closed Process Invariance.Ron Mallon & Jonathan M. Weinberg - 2006 - Philosophy of Science 73 (3):323-344.
    Controversies over the innateness of cognitive processes, mechanisms, and structures play a persistent role in driving research in philosophy as well as the cognitive sciences, but the appropriate way to understand the category of the innate remains subject to dispute. One venerable approach in philosophy and cognitive science merely contrasts innate features with those that are learned. In fact, Jerry Fodor has recently suggested that this remains our best handle on innateness.
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  • Gene.Hans-Jörg Rheinberger - 2008 - Stanford Encyclopedia of Philosophy.
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  • Experimental philosophy of science.Paul E. Griffiths & Karola Stotz - 2008 - Philosophy Compass 3 (3):507–521.
    Experimental philosophy of science gathers empirical data on how key scientific concepts are understood by particular scientific communities. In this paper we briefly describe two recent studies in experimental philosophy of biology, one investigating the concept of the gene, the other the concept of innateness. The use of experimental methods reveals facts about these concepts that would not be accessible using the traditional method of intuitions about possible cases. It also contributes to the study of conceptual change in science, which (...)
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  • Reports of the death of the Gene are greatly exaggerated.Rob Knight - 2007 - Biology and Philosophy 22 (2):293-306.
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  • Rethinking Ethnography for Philosophy of Science.Nancy J. Nersessian & Miles MacLeod - 2022 - Philosophy of Science 89 (4):721-741.
    We lay groundwork for applying ethnographic methods in philosophy of science. We frame our analysis in terms of two tasks: to identify the benefits of an ethnographic approach in philosophy of science and to structure an ethnographic approach for philosophical investigation best adapted to provide information relevant to philosophical interests and epistemic values. To this end, we advocate for a purpose-guided form of cognitive ethnography that mediates between the explanatory and normative interests of philosophy of science, while maintaining openness and (...)
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  • Three Roles of Empirical Information in Philosophy: Intuitions on Mathematics do Not Come for Free.Deniz Sarikaya, José Antonio Pérez-Escobar & Deborah Kant - 2021 - Kriterion – Journal of Philosophy 35 (3):247-278.
    This work gives a new argument for ‘Empirical Philosophy of Mathematical Practice’. It analyses different modalities on how empirical information can influence philosophical endeavours. We evoke the classical dichotomy between “armchair” philosophy and empirical/experimental philosophy, and claim that the latter should in turn be subdivided in three distinct styles: Apostate speculator, Informed analyst, and Freeway explorer. This is a shift of focus from the source of the information towards its use by philosophers. We present several examples from philosophy of mind/science (...)
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  • Experimental philosophy of medicine and the concepts of health and disease.Walter Veit - 2020 - Theoretical Medicine and Bioethics 42 (3):169-186.
    If one had to identify the biggest change within the philosophical tradition in the twenty-first century, it would certainly be the rapid rise of experimental philosophy to address differences in intuitions about concepts. It is, therefore, surprising that the philosophy of medicine has so far not drawn on the tools of experimental philosophy in the context of a particular conceptual debate that has overshadowed all others in the field: the long-standing dispute between so-called naturalists and normativists about the concepts of (...)
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  • A plea for an experimental philosophy of medicine.Andreas De Block & Kristien Hens - 2021 - Theoretical Medicine and Bioethics 42 (3):81-89.
    This special issue aims to explore and investigate a new subfield, namely experimental philosophy of medicine. Whereas experimental philosophy is relatively new on the philosophical block, some of its takes and findings have already shaped central debates in ethics, philosophy of action, philosophy of language, and epistemology. Interestingly, the approach of this program was for a long time almost wholly ignored within bioethics and philosophy of medicine—although this seems to have changed somewhat recently. In this introduction, we briefly sketch the (...)
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  • Ethischer Diskurs zu Epigenetik und Genomeditierung: die Gefahr eines (epi-)genetischen Determinismus und naturwissenschaftlich strittiger Grundannahmen.Karla Karoline Sonne Kalinka Alex & Eva C. Winkler - 2021 - In Boris Fehse, Ferdinand Hucho, Sina Bartfeld, Stephan Clemens, Tobias Erb, Heiner Fangerau, Jürgen Hampel, Martin Korte, Lilian Marx-Stölting, Stefan Mundlos, Angela Osterheider, Anja Pichl, Jens Reich, Hannah Schickl, Silke Schicktanz, Jochen Taupitz, Jörn Walter, Eva Winkler & Martin Zenke (eds.), Fünfter Gentechnologiebericht: Sachstand und Perspektiven für Forschung und Anwendung. pp. 299-323.
    Slightly modified excerpt from the section 13.4 Zusammenfassung und Ausblick (translated into englisch): This chapter is based on an analysis of ethical debates on epigenetics and genome editing, debates, in which ethical arguments relating to future generations and justice play a central role. The analysis aims to contextualize new developments in genetic engineering, such as genome and epigenome editing, ethically. At the beginning, the assumptions of "genetic determinism," on which "genetic essentialism" is based, of "epigenetic determinism" as well as "genetic" (...)
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  • On Drugs.Sam Baron, Sara Linton & Maureen A. O’Malley - 2023 - Journal of Medicine and Philosophy 48 (6):551-564.
    Despite their centrality to medicine, drugs are not easily defined. We introduce two desiderata for a basic definition of medical drugs. It should: (a) capture everything considered to be a drug in medical contexts and (b) rule out anything that is not considered to be a drug. After canvassing a range of options, we find that no single definition of drugs can satisfy both desiderata. We conclude with three responses to our exploration of the drug concept: maintain a monistic concept, (...)
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  • (1 other version)A Theory of Conceptual Advance: Explaining Conceptual Change in Evolutionary, Molecular, and Evolutionary Developmental Biology.Ingo Brigandt - 2006 - Dissertation, University of Pittsburgh
    The theory of concepts advanced in the dissertation aims at accounting for a) how a concept makes successful practice possible, and b) how a scientific concept can be subject to rational change in the course of history. Traditional accounts in the philosophy of science have usually studied concepts in terms only of their reference; their concern is to establish a stability of reference in order to address the incommensurability problem. My discussion, in contrast, suggests that each scientific concept consists of (...)
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  • Empirical Philosophy of Science.Kostas Kampourakis - 2019 - Science & Education 28 (1-2):1-3.
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  • Experimental philosophy of biology: notes from the field.Karola Stotz - 2009 - Studies in History and Philosophy of Science Part A 40 (2):233-237.
    I use a recent ‘experimental philosophy’ study of the concept of the gene conducted by myself and collaborators to discuss the broader epistemological framework within which that research was conducted, and to reflect on the relationship between science, history and philosophy of science, and society.Keywords: Experimental philosophy; Biohumanities; Representing Genes Project; Gene concept; Science criticism; Conceptual ecology.
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  • (1 other version)Gene expression and the concept of the phenotype.Ohad Nachtomy, Ayelet Shavit & Zohar Yakhini - 2007 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 38 (1):238-254.
    While the definition of the ‘genotype’ has undergone dramatic changes in the transition from classical to molecular genetics, the definition of the ‘phenotype’ has remained for a long time within the classical framework. In addition, while the notion of the genotype has received significant attention from philosophers of biology, the notion of the phenotype has not. Recent developments in the technology of measuring gene-expression levels have made it possible to conceive of phenotypic traits in terms of levels of gene expression. (...)
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  • Gene concepts and Genethics: Beyond exceptionalism.Péter Kakuk - 2008 - Science and Engineering Ethics 14 (3):357-375.
    The discursive explosion that was provoked by the new genetics could support the impression that the ethical and social problems posed by the new genetics are somehow exceptional in their very nature. According to this view we are faced with special ethical and social problems that create a challenge so fundamental that the special label of genethics is needless to justify. The historical account regarding the evolution of the gene concepts could serve us to highlight the limits of what we (...)
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  • Again, what the philosophy of biology is not.Werner Callebaut - 2005 - Acta Biotheoretica 53 (2):93-122.
    There are many things that philosophy of biology might be. But, given the existence of a professional philosophy of biology that is arguably a progressive research program and, as such, unrivaled, it makes sense to define philosophy of biology more narrowly than the totality of intersecting concerns biologists and philosophers (let alone other scholars) might have. The reasons for the success of the “new” philosophy of biology remain poorly understood. I reflect on what Dutch and Flemish, and, more generally, European (...)
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  • Follow *the* science? On the marginal role of the social sciences in the COVID-19 pandemic.Simon Lohse & Stefano Canali - 2021 - European Journal for Philosophy of Science 11 (4):1-28.
    In this paper, we use the case of the COVID-19 pandemic in Europe to address the question of what kind of knowledge we should incorporate into public health policy. We show that policy-making during the COVID-19 pandemic has been biomedicine-centric in that its evidential basis marginalised input from non-biomedical disciplines. We then argue that in particular the social sciences could contribute essential expertise and evidence to public health policy in times of biomedical emergencies and that we should thus strive for (...)
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  • (1 other version)Teaching Biologists the Philosophy of Their Time: Kostas Kampourakis and Tobias Uller: Philosophy of Science for Biologists. Cambridge University Press, Cambridge, UK, 2020, 340pp, ISBN: 9781108740708. [REVIEW]Sophie Juliane Veigl - 2021 - Acta Biotheoretica 69 (3):483-491.
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  • Gene names as proper names of individuals: An assessment.Thomas A. C. Reydon - 2009 - British Journal for the Philosophy of Science 60 (2):409-432.
    According to a recent suggestion, the names of gene taxa should be conceived of as referring to individuals with concrete genes as their parts, just as the names of biological species are often understood as denoting individuals with organisms as their parts. Although prima facie this suggestion might advance the debate on gene concepts in a similar way as the species-are-individuals thesis advanced the debate on species concepts, I argue that the principal arguments in support of the gene-individuality thesis are (...)
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  • Genetic information as instructional content.Ulrich E. Stegmann - 2005 - Philosophy of Science 72 (3):425-443.
    The concept of genetic information is controversial because it attributes semantic properties to what seem to be ordinary biochemical entities. I argue that nucleic acids contain information in a semantic sense, but only about a limited range of effects. In contrast to other recent proposals, however, I analyze genetic information not in terms of a naturalized account of biological functions, but instead in terms of the way in which molecules determine their products during processes known as template-directed syntheses. I argue (...)
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  • Planets, pluralism, and conceptual lineage.Carl Brusse - 2016 - Studies in History and Philosophy of Science Part B: Studies in History and Philosophy of Modern Physics 53 (C):93-106.
    Conceptual change can occur for a variety of reasons; some more scientifically significant than others. The 2006 definition of ‘planet’, which saw Pluto reclassified as a dwarf planet, is an example toward the more mundane end of the scale. I argue however that this case serves as a useful example of a related phenomenon, whereby what appears to be a single kind term conceals two or more distinct concepts with independent scientific utility. I examine the historical background to this case, (...)
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  • How biological background assumptions influence scientific risk evaluation of stacked genetically modified plants: an analysis of research hypotheses and argumentations.Fredrik Andersen & Elena Rocca - 2017 - Life Sciences, Society and Policy 13 (1):1-20.
    Scientific risk evaluations are constructed by specific evidence, value judgements and biological background assumptions. The latter are the framework-setting suppositions we apply in order to understand some new phenomenon. That background assumptions co-determine choice of methodology, data interpretation, and choice of relevant evidence is an uncontroversial claim in modern basic science. Furthermore, it is commonly accepted that, unless explicated, disagreements in background assumptions can lead to misunderstanding as well as miscommunication. Here, we extend the discussion on background assumptions from basic (...)
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  • How to Understand the Gene in the Twenty-First Century?Lia Midori Nascimento Meyer, Gilberto Cafezeiro Bomfim & Charbel Niño El-Hani - 2013 - Science & Education 22 (2):345-374.
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  • Updating the Model Definition of the Gene in the Modern Genomic Era with Implications for Instruction.Mike U. Smith & Linda R. Adkison - 2010 - Science & Education 19 (1):1-20.
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  • Book Forum.Benjamin Goldberg - forthcoming - Studies in History and Philosophy of Science Part A.
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  • Characterisation of the Context-Dependence of the Gene Concept in Research Articles.Veronica S. Flodin - 2017 - Science & Education 26 (1-2):141-170.
    The purpose of this study is to interpret and qualitatively characterise the content in some research articles and evaluate cases of possible difference in meanings of the gene concept used. Using a reformulation of Hirst’s criteria of forms of knowledge, articles from five different sub-disciplines in biology were characterised according to knowledge project, methods used and conceptual contexts. Depending on knowledge project, the gene may be used as a location of recombination, a target of regulatory proteins, a carrier of regulatory (...)
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  • Hybrid Deterministic Views About Genes in Biology Textbooks: A Key Problem in Genetics Teaching.Vanessa Carvalho dos Santos, Leyla Mariane Joaquim & Charbel Niño El-Hani - 2012 - Science & Education 21 (4):543-578.
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