The literature on health and diseases is usually presented as an opposition between naturalism and normativism. This article argues that such a picture is too simplistic: there is not one opposition between naturalism and normativism, but many. I distinguish four different domains where naturalist and normativist claims can be contrasted: (1) ordinary usage, (2) conceptually clean versions of “health” and “disease,” (3) the operationalization of dysfunction, and (4) the justification for that operationalization. In the process I present new arguments in (...) response to Schwartz (2007) and Hausman (2012) and expose a link between the arguments made by Schwartz (2007) and Kingma (2010). Distinguishing naturalist claims at these four domains will allow us to make progress by (1) providing more nuanced, intermediate positions about a possible role for values in health and disease; and (2) assisting in the addressing of relativistic worries about the value-ladenness of health and disease. (shrink)

During the first half of the twentieth century, mainstream answers to the foundational crisis, mainly triggered by Russell and Gödel, remained largely perfectibilist in nature. Along with a general naturalist wave in the philosophy of science, during the second half of that century, this idealist picture was finally challenged and traded in for more realist ones. Next to the necessary preliminaries, the present paper proposes a structured view of various philosophical accounts of mathematics indebted to this general idea, laying the (...) ground for a desirable integration of their strenghts. (shrink)

The premise of biological modularity is an ontological claim that appears to come out of practice. We understand that the biological world is modular because we can manipulate different parts of organisms in ways that would only work if there were discrete parts that were interchangeable. This is the foundation of the BioBrick assembly method widely used in synthetic biology. It is one of a number of methods that allows practitioners to construct and reconstruct biological pathways and devices using DNA (...) libraries of standardized parts with known functions. In this paper, we investigate how the practice of synthetic biology reconfigures biological understanding of the key concepts of modularity and evolvability. We illustrate how this practice approach takes engineering knowledge and uses it to try to understand biological organization by showing how the construction of functional parts and processes can be used in synthetic experimental evolution. We introduce a new approach within synthetic biology that uses the premise of a parts-based ontology together with that of organismal self-organization to optimize orthogonal metabolic pathways in E. coli. We then use this and other examples to help characterize semisynthetic categories of modularity, parthood, and evolvability within the discipline. (shrink)

Philosophical investigation in synthetic biology has focused on the knowledge-seeking questions pursued, the kind of engineering techniques used, and on the ethical impact of the products produced. However, little work has been done to investigate the processes by which these epistemological, metaphysical, and ethical forms of inquiry arise in the course of synthetic biology research. An attempt at this work relying on a particular area of synthetic biology will be the aim of this chapter. I focus on the reengineering of (...) metabolic pathways through the manipulation and construction of small DNA-based devices and systems synthetic biology. Rather than focusing on the engineered products or ethical principles that result, I will investigate the processes by which these arise. As such, the attention will be directed to the activities of practitioners, their manipulation of tools, and the use they make of techniques to construct new metabolic devices. Using a science-in-practice approach, I investigate problems at the intersection of science, philosophy of science, and sociology of science. I consider how practitioners within this area of synthetic biology reconfigure biological understanding and ethical categories through active modelling and manipulation of known functional parts, biological pathways for use in the design of microbial machines to solve problems in medicine, technology, and the environment. We might describe this kind of problem-solving as relying on what Helen Longino referred to as “social cognition” or the type of scientific work done within what Hasok Chang calls “systems of practice”. My aim in this chapter will be to investigate the relationship that holds between systems of practice within metabolic engineering research and social cognition. I will attempt to show how knowledge and normative valuation are generated from this particular network of practitioners. In doing so, I suggest that the social nature of scientific inquiry is ineliminable to both knowledge acquisition and ethical evaluations. (shrink)

Philosophy of biology, perhaps more than any other philosophy of science, is a discipline in flux. What counts as consensus and key arguments in certain areas changes rapidly.The publication of Contemporary Debates in Philosophy of Biology (2010 Wiley-Blackwell) is reviewed and is used as a catalyst to a discussion of the recent expansion of subjects and perspectives in the philosophy of biology as well as their diverse epistemological and methodological commitments.

In this paper, I attempt to reconstruct Schelling’s theory of organism, primarily as it is elaborated in the First Outline of a System of the Philosophy of Nature and the Introduction to the Outline. First, I discuss the challenge that the properties of organisms presented to the dominant scientific viewpoint by the end of the eighteenth century. I present different responses to this challenge, including reductive materialism, metaphysical and heuristic vitalism, and the Kantian response, and I situate Schelling’s account of (...) organism with respect to these responses. I argue that while Schelling agrees with vitalism in that he wants to preserve the specificity of organic phenomena, he rejects principles such as vital forces or the formative drive postulated by vitalism, even for purely heuristic purposes. I argue that Schelling understands organisms fundamentally in terms of the coordinated functioning of their organs. I further clarify Schelling’s account of problematic organic phenomena by focusing on his treatment of the relation between organic activity and organic receptivity. For Schelling, organic activity and organic receptivity mutually condition each other. I provide a detailed account of how this is supposed to work. (shrink)

In this introductory article we reconstruct several broad developments in the scholarship on Kant’s theory of natural science with a particular focus on the Anglophone context over the past half-century. Our goal is to illuminate the co-development of Kant scholarship and the philosophy of science during this period and to identify points of influence in both directions. In section 2 we present an overview of the scholarship on Kant’s account of natural laws. In section 3 we survey the diverse interpretations (...) of Kant’s views on biology and consider recent appeals to Kant by philosophers of biology. In section 4 we explore several recent developments in philosophy of science that have potential synergies with Kant scholarship. Our aim is not simply to establish that Kant’s philosophy can have relevance for philosophy of science but also to point out where it has been and continues to be relevant. Appreciating this relevance, we suggest, can help identify productive lines of inquiry for Kant studies. (shrink)

The study of similarity is fundamental to biological inquiry. Many homology concepts have been formulated that function successfully to explain similarity in their native domains, but fail to provide an overarching account applicable to variably interconnected and independent areas of biological research despite the monistic standpoint from which they originate. The use of multiple, explicitly articulated homology concepts, applicable at different levels of the biological hierarchy, allows a more thorough investigation of the nature of biological similarity. Responsible epistemological pluralism as (...) advocated herein is generative of fruitful and innovative biological research, and is appropriate given the metaphysical pluralism that underpins all of biology. (shrink)

ArgumentEvolutionary psychologists argue that because humans are biological creatures, cultural explanationsmustinclude biology. They thus offer to unify the natural and social sciences. Evolutionary psychologists rely on a specific history of cultural anthropology, particularly the work of Alfred Kroeber to make this point. A close examination of the history of cultural anthropology reveals that Kroeber acknowledged that humans were biological and culture had a biological foundation; however, he argued that we should treat culture as autonomous because that would bring benefits to (...) the biological sciences as well as the human sciences. Hence, the historical caricature of his work by evolutionary psychology fails. The paper concludes that cultural anthropologists were successful in creating their discipline, at least in part, because they argued by pragmatic definition. Evolutionary psychology, on the other hand, offers an essentialist definition of “culture” and thus offers a much less promising vision of interdisciplinary collaboration. (shrink)

This paper argues that from an ethical point of view tolerance, which is simply one of a number of possible responses to ethical pluralism, is not an acceptable ideal. It fails to acknowledge and appreciate the good in other forms of life and thereby does not adequately respect the people who live these lives. Toleration limits the range of goods we might appreciate in our own lives and in the lives of those we care most about, and it tends to (...) lead to a number of deformations or personal failures of character. In place of tolerance, we should embrace ethical promiscuity—a view that not only acknowledges ethical pluralism but also offers good reasons to celebrate this state of affairs. (shrink)

Since the collapse of the 'received view' consensus in the late 1960s, the question of scientific realism has been a major preoccupation of philosophers of science. This paper sketches the history of this debate, which grew from developments in the philosophy of language, but eventually took on an autonomous existence. More recently, the debate has tended towards more 'local' considerations of particular scientific episodes as a way of getting purchase on the issues. The paper reviews two such approaches, Fine's and (...) Hacking's, describing their positions, their prospects, and how they are related. Finally, the paper suggests that local philosophies of science offer a way for our discipline to engage more fruitfully with the public and the scientific community. (shrink)

This paper examines the problem of natural kinds, a key problem within feminist theory, and argues for a non-instrumental realist account of group identity. I suggest that a reconstructed theory of essence helps to make sense of group membership because it combines a conventional account of groups with a realist commitment to there being something responsible for the appearance of regularities in the world. The claim that natural kind membership is a matter of similarity relationships manages to avoid metaphysical, universal (...) property-based essentialism and, at the same time, points to interested generative mechanisms underlying the appearance of the regularities that make sense of kind membership. Finally, I suggest that the concepts 'real essence' and 'internal constitution' offer a new way to conceive 'sex' and 'gender', and that Adorno's notion of non-identity is a way to think group membership non-instrumentally. (shrink)

Species serve as both the basic units of macroevolutionary studies and as the basic units of taxonomic classification. In this paper I argue that the taxa identified as species by the Phylogenetic Species Concept (Mishler and Brandon 1987) are the units of biological organization most causally relevant to the evolutionary process but that such units exist at multiple levels within the hierarchy of any phylogenetic lineage. The PSC gives us no way of identifying one of these levels as the privileged (...) level on which taxonomic classifications can be based. (shrink)

All the major inter-theoretic relations of fundamental science are asymptotic ones, e.g. quantum theory as Planck's constant h 0, yielding (roughly) Newtonian mechanics. Thus asymptotics ultimately grounds claims about inter-theoretic explanation, reduction and emergence. This paper examines four recent, central claims by Batterman concerning asymptotics and reduction. While these claims are criticised, the discussion is used to develop an enriched, dynamically-based account of reduction and emergence, to show its capacity to illuminate the complex variety of inter-theory relationships in physics, and (...) to provide a principled resolution to such persistent philosophical problems as multiple realisability and the nature of the special sciences. Introduction Exposition Examination I: Claims (1) and (2), asymptotic explanation and reference Examination II: Claim (3), reduction and singular asymptotics Examination III: Claim (4), emergence and multiple realisability Conclusion. (shrink)

In this paper I defend the metaphysics of race as a valuable philosophical project against deflationism about race. The deflationists argue that metaphysical debate about the reality of race amounts to a non-substantive verbal dispute that diverts attention from ethical and practical issues to do with ‘race.’ In response, I show that the deflationists mischaracterize the field and fail to capture what most metaphysicians of race actually do in their work, which is almost always pluralist and very often normative and (...) explicitly political. Even if debates about the reality of race turn out to be verbal disputes, they are substantive, and worth having. (shrink)

This paper reviews how research on the demarcation problem has developed, starting from Popper’s criterion of falsifiability and ending with recent naturalistically oriented approaches. The main differences between traditional and contemporary approaches to the problem are explicated in terms of six postulates called the traditional assumptions. It is argued that all of the assumptions can be dismissed without giving up on the demarcation problem and that doing so might benefit further discussions on pseudoscience. Four present-day research movements on evaluating the (...) boundaries of science are introduced: (1) philosophy of pseudoscience, (2) social epistemology of dissent, (3) agnotology, and (4) evaluation of expertise. Researchers working within these areas have abandoned some or all traditional assumptions. (shrink)

“Practice” has become a ubiquitous term in the history of science, and yet historians have not always reflected on its philosophical import and especially on its potential connections with ethics. In this essay, we draw on the work of the virtue ethicist Alasdair MacIntyre to develop a theory of “communal practices” and explore how such an approach can inform the history of science, including allegations about the corruption of science by wealth or power; consideration of scientific ethics or “moral economies”; (...) the role of values in science; the ethical distinctiveness of scientific vocations; and the relationship between history of science and the practice of science itself. (shrink)

The relation between method, concept and theory in science is complicated. I seek to shed light on that relation by considering an instance of it in systematics: The additional challenges phylogeneticists face when reconstructing phylogeny not at a single level, but simultaneously at multiple levels of the hierarchy. How does this complicate the task of phylogenetic inference, and how might it inform and shape the conceptual foundations of phylogenetics? This offers a lens through which the interplay of method, theory and (...) concepts may be understood in systematics, which, in turn, provides data for a more general account. (shrink)

In this article I assess the problems and prospects of a microstructural approach to chemical substances. Saul Kripke and Hilary Putnam famously claimed that to be gold is to have atomic number 79 and to be water is to be H2O. I relate the first claim to the concept of element in the history of chemistry, arguing that the reference of element names is determined by atomic number. Compounds are more difficult: water is so complex and heterogeneous at the molecular (...) level that `water is H2O’ seems false under some interpretations. I sketch a response to this problem. (shrink)

In this paper I explore Aristotle’s views on natural kinds and the compatibility of pluralism and realism, a topic that has generated considerable interest among contemporary philosophers. I argue that, when it came to zoology, Aristotle denied that there is only one way of organizing the diversity of the living world into natural kinds that will yield a single, unified system of classification. Instead, living things can be grouped and regrouped into various cross-cutting kinds on the basis of objective similarities (...) and differences in ways that subserve the explanatory context. Since the explanatory aims of zoology are diverse and variegated, the kinds it recognizes must be equally diverse and variegated. At the same time, there are certain constraints on which kinds can be selected. And those constraints derive more from the causal structure of the world than from the proclivities of the classifier (hence the realism). This distinguishes Aristotle’s version of pluralistic realism from those contemporary versions (like Dupré’s “promiscuous realism”) that treat all or most classifications of a given domain as equally legitimate and not just a sub-set of kinds recognized by the science that studies it. By contrast, Aristotle privileges scientifically important kinds on the basis of their role in causal investigations. On this picture natural kinds are those kinds with the sort of causal structure that allows them to enter into scientific explanations. In the final section I argue that Aristotle’s zoology should remain of interest to philosophers and biologists alike insofar as it combines a pluralistic form of realism with a rank-free approach to classification. (shrink)

Marc Ereshefsky’s project of eliminative pluralism holds that, as there is no unifying feature among all species concepts, we ought to doubt the existence of the species category. Here, I argue that one promising strategy for saving the species category is to reframe it as a natural kind after the practice turn. I suggest situating the species category within a recent account of natural kinds proposed by Marc Ereshefsky and Thomas Reydon called “scientific kinds”. Scientific kinds highlight ontological boundaries. More (...) importantly, they recognize boundaries drawn from the lab and the field, not only from the armchair. The point of this exercise is to situate the species category within an account of natural kinds that is sensitive to scientific practice. In order to argue for a realist interpretation of the species category, and not merely a pragmatic one, I rely on an approach to scientific metaphysics from Ken Waters that shifts the attention from “theory focused” to “practice-centered” analysis. (shrink)

Following Kripke and Putnam, the received view of chemical kinds has been a microstructuralist one. To be a microstructuralist about chemical kinds is to think that membership in said kinds is conferred by microstructural properties. Recently, the received microstructuralist view has been elaborated and defended, but it has also been attacked on the basis of complexities, both chemical and ontological. Here, I look at which complexities really challenge the microstructuralist view; at how the view itself might be made more complicated (...) in order to accommodate such challenges; and finally, at what this increasingly complicated picture implies for our standard assessment of chemical kindhood—primarily, for the widespread assumption that chemical kinds in general are more neat and tidy than those messy biological ones. _1_ The Received View _2_ A Taxonomy of Chemical Kinds _3_ Atomic Number _4_ H2O, H3O+, OH−, and More _5_ Complicating the Microstructuralist Picture _6_ Concrete and Other Mixtures _7_ Macromolecules, Especially Proteins _8_ Abandoning Sameness of Elemental Composition _9_ Not So Different after All. (shrink)

There is a perennial philosophical dream of a certain natural order for the natural kinds. The name of this dream is ‘the hierarchy requirement’. According to this postulate, proper natural kinds form a taxonomy which is both unique and traditional. Here I demonstrate that complex scientific objects exist: objects which generate different systems of scientific classification, produce myriad legitimate alternatives amongst the nonetheless still natural kinds, and make the hierarchical dream impossible to realize, except at absurdly great cost. Philosophical hopes (...) for a certain order in nature cannot be fulfilled. Natural kinds crosscut one another, ubiquitously so, and this crosscutting spells the end of the hierarchical dream. (shrink)

expose some gaps and difficulties in the argument for the causal Markov condition in our essay ‘Independence, Invariance and the Causal Markov Condition’ ([1999]), and we are grateful for the opportunity to reformulate our position. In particular, Cartwright disagrees vigorously with many of the theses we advance about the connection between causation and manipulation. Although we are not persuaded by some of her criticisms, we shall confine ourselves to showing how our central argument can be reconstructed and to casting doubt (...) on Cartwright's claim that the causal Markov condition typically fails when there are indeterministic by-products. Why believe the causal Markov condition? Causation and manipulation The argument Indeterministic by-products and the causal Markov condition The chemical factory counterexample and PM2 Conclusions: causation and manipulability. (shrink)

Challenges the revised standard historiography on Wundt as a psychologist. Considers the concept of psychology as a natural science. Examines the relations between psychology and philosophy before and after 1900. Reflects on the notion of disciplinehood as it affects historical narratives.

The problem of demarcation continues to attract attention, in part because solutions are perceived to have enormous social significance. The civic motivation, however, I argue is in tension with the heterogeneity of the sciences. Philosophers of science would be better employed reflecting on the features, causes, and consequences, of created, scientific controversies. These arise when relevant experts are in broad agreement about what conclusions can sensibly be drawn from available evidence, but the public perceives an expert community deeply divided and (...) conclusions that are plagued by profound and systemic uncertainty. In the second part of the paper I explore this concept further. (shrink)

A definition of pseudoscience is proposed, according to which a statement is pseudoscientific if and only if it (1) pertains to an issue within the domains of science, (2) is not epistemically warranted, and (3) is part of a doctrine whose major proponents try to create the impression that it is epistemically warranted. This approach has the advantage of separating the definition of pseudoscience from the justification of the claim that science represents the most epistemically warranted statements. The definition is (...) used to explain why proponents of widely divergent criteria for the demarcation between science and pseudoscience tend to be in almost complete agreement on the particular demarcations that should presumably be based on these general criteria. (shrink)

The rosy dawn of my title refers to that optimistic time when the logical concept of a natural kind originated in Victorian England. The scholastic twilight refers to the present state of affairs. I devote more space to dawn than twilight, because one basic problem was there from the start, and by now those origins have been forgotten. Philosophers have learned many things about classification from the tradition of natural kinds. But now it is in disarray and is unlikely to (...) be put back together again. My argument is less founded on objections to the numerous theories now in circulation, than on the sheer proliferation of incompatible views. There no longer exists what Bertrand Russell called ‘the doctrine of natural kinds’—one doctrine. Instead we have a slew of distinct analyses directed at unrelated projects. (shrink)

Several advocates of the lively field of “metaphysics of science” have recently argued that a naturalistic metaphysics should be based solely on current science, and that it should replace more traditional, intuition-based, forms of metaphysics. The aim of the present paper is to assess that claim by examining the relations between metaphysics of science and general metaphysics. We show that the current metaphysical battlefield is richer and more complex than a simple dichotomy between “metaphysics of science” and “traditional metaphysics”, and (...) that it should instead be understood as a three dimensional “box”, with one axis distinguishing “descriptive metaphysics” from “revisionary metaphysics”, a second axis distinguishing a priori from a posteriori metaphysics, and a third axis distinguishing “commonsense metaphysics”, “traditional metaphysics” and “metaphysics of science”. We use this three-dimensional figure to shed light on the project of current metaphysics of science, and to demonstrate that, in many instances, the target of that project is not defined with enough precision and clarity. (shrink)

In earlier work I have claimed that emotion and some emotions are not `natural kinds'. Here I clarify what I mean by `natural kind', suggest a new and more accurate term, and discuss the objection that emotion and emotions are not descriptive categories at all, but fundamentally normative categories.

A common reductionist assumption is that macro-scale behaviors can be described "bottom-up" if only sufficient details about lower-scale processes are available. The view that an "ideal" or "fundamental" physics would be sufficient to explain all macro-scale phenomena has been met with criticism from philosophers of biology. Specifically, scholars have pointed to the impossibility of deducing biological explanations from physical ones, and to the irreducible nature of distinctively biological processes such as gene regulation and evolution. This paper takes a step back (...) in asking whether bottom-up modeling is feasible even when modeling simple physical systems across scales. By comparing examples of multi-scale modeling in physics and biology, we argue that the “tyranny of scales” problem presents a challenge to reductive explanations in both physics and biology. The problem refers to the scale-dependency of physical and biological behaviors that forces researchers to combine different models relying on different scale-specific mathematical strategies and boundary conditions. Analyzing the ways in which different models are combined in multi-scale modeling also has implications for the relation between physics and biology. Contrary to the assumption that physical science approaches provide reductive explanations in biology, we exemplify how inputs from physics often reveal the importance of macro-scale models and explanations. We illustrate this through an examination of the role of biomechanics modeling in developmental biology. In such contexts, the relation between models at different scales and from different disciplines is neither reductive nor completely autonomous, but interdependent. (shrink)

This paper argues that conceptualizing unity as "interconnection" (rather than reduction) provides a more fruitful and versatile framework for the philosophical study of scientific unification. Building on the work of Darden and Maull, Kitcher, and Kincaid, I treat unity as a relationship between fields: two fields become more integrated as the number and/or significance of interfield connections grow. Even when reduction fails, two theories or fields can be unified (integrated) in significant ways. I highlight two largely independent dimensions of unification. (...) Fields are theoretically unified to the extent that we understand how the ontologies, concepts, and generalizations of these fields are connected. (Reductionism is one form of theoretical unity, but not the only form). Fields are practically unified through heuristic connections (e.g., using the heuristics of one field to generate hypotheses in another field) and by the development of methods for integrating the qualitatively distinct bodies of data generated by the two fields. I discuss the relationship between paleontological and neontological systematics to illustrate the utility of conceptualizing unity as interconnection. (shrink)