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  1. The Politics of Human Enhancement and the European Union.Christopher Coenen, Mirjam Schuijff & Martijntje Smits - 2011 - In Julian Savulescu, Ruud ter Meulen & Guy Kahane (eds.), Enhancing Human Capacities. Blackwell. pp. 521–535.
    Human enhancement issues are not merely academic: the technologies and trends involved give rise to new needs and social demands, provide opportunities for individuals and society, and present new risks. They also challenge crucial cultural notions, social concepts and views of the human condition, and may cause new forms of social pressure and social exclusion. This chapter reports on a systematic attempt by the European Technology Assessment Group (ETAG), conducted on behalf of the Science and Technology Options Assessment (STOA) panel (...)
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  • Challenging human enhancement.Alberto Giubilini & Sagar Sanyal - 2016 - In Steve Clarke, Julian Savulescu, C. A. J. Coady, Alberto Giubilini & Sagar Sanyal (eds.), The Ethics of Human Enhancement: Understanding the Debate. Oxford, United Kingdom: Oxford University Press.
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  • Special Supplement: Is Better Always Good? The Enhancement Project.Erik Parens - 1998 - Hastings Center Report 28 (1):S1.
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  • Bioconservatism, Partiality, and the Human-Nature Objection to Enhancement.Pugh Jonathan, Guy Kahane & Julian Savulescu - 2016 - The Monist 99 (4):406-422.
    “Bioconservatives” in the human enhancement debate endorse the conservative claim that we should reject the use of biotechnologies that enhance natural human capacities. However, they often ground their objections to enhancement with contestable claims about human nature that are also in tension with other common tenets of conservatism. We argue that bioconservatives could raise a more plausible objection to enhancement by invoking a strain of conservative thought developed by G.A. Cohen. Although Cohen’s conservatism is not sufficient to fully revive the (...)
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  • (1 other version)Moral Status of Enhanced Beings: What Do We Owe the Gods?J. Savulescu - 2009 - Human Enhancement.
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  • The Ethics of Germline Gene Editing.Gyngell Christopher, Douglas Thomas & Savulescu Julian - 2017 - Journal of Applied Philosophy 34 (4):498-513.
    Germline Gene Editing has enormous potential both as a research tool and a therapeutic intervention. While other types of gene editing are relatively uncontroversial, GGE has been strongly resisted. In this article, we analyse the ethical arguments for and against pursuing GGE by allowing and funding its development. We argue there is a strong case for pursuing GGE for the prevention of disease. We then examine objections that have been raised against pursuing GGE and argue that these fail. We conclude (...)
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  • Against Relativism: Cultural Diversity and the Search for Ethical Universals in Medicine.Ruth Macklin & John W. Cook - 2001 - Philosophical Quarterly 51 (202):121-124.
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  • (2 other versions)The Idea of Nature.R. G. Collingwood - 1945 - Mind 54 (215):274-279.
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  • (1 other version)The Great Chain of Being. A Study of the History of an Idea. [REVIEW]H. T. C. - 1936 - Journal of Philosophy 33 (21):580.
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  • Disorder as harmful dysfunction: A conceptual critique of DSM-III-R's definition of mental disorder.Jerome C. Wakefield - 1992 - Psychological Review 99 (2):232-247.
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  • Enhancement.Thomas Murray - 2007 - In Bonnie Steinbock (ed.), The Oxford handbook of bioethics. New York: Oxford University Press.
    Understanding the ethics of enhancement begins with getting clear about the concept, as well as the factors likely to move people to pursue biomedical enhancement. This article first considers the usefulness of the distinction between therapy and enhancement for understanding the ethics of enhancement. Once the conceptual underbrush has been cleared away, we can move on to ethics. The next section examines critically a number of arguments that have been offered to defend biomedical enhancement, or, at least, to claim that (...)
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  • Defining disease: Much ado about nothing?Jennifer Worrall & John Worrall - 2001 - In Anna-Teresa Tymieniecka & Evandro Agazzi (eds.), Life interpretation and the sense of illness within the human condition. Boston: Kluwer Academic Publishers. pp. 33--55.
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  • Disease.Rachel Cooper - 2002 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 33 (2):263-282.
    This paper examines what it is for a condition to be a disease. It falls into two sections. In the first I examine the best existing account of disease (as proposed by Christopher Boorse) and argue that it must be rejected. In the second I outline a more acceptable account of disease. According to this account, by disease we mean a condition that it is a bad thing to have, that is such that we consider the afflicted person to have (...)
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  • Bioconservatism, Bioliberalism, and the Wisdom of Reflecting on Repugnance.Rebecca Roach & Steve Clarke - 2009 - Monash Bioethics Review 28 (1):1-21.
    We consider the current debate between bioconservatives and their chief opponents — whom we dub bioliberals — about the moral acceptability of human enhancement and the policy implications of moral debates about enhancement. We argue that this debate has reached an impasse, largely because bioconservatives hold that we should honour intuitions about the special value of being human, even if we cannot identify reasons to ground those intuitions. We argue that although intuitions are often a reliable guide to belief and (...)
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  • From Utopia to Science: Challenges of Personalised Genomics Information for Health Management and Health Enhancement. [REVIEW]Hub Zwart - 2009 - Medicine Studies 1 (2):155-166.
    From 1900 onwards, scientists and novelists have explored the contours of a future society based on the use of “anthropotechnologies” (techniques applicable to human beings for the purpose of performance enhancement ranging from training and education to genome-based biotechnologies). Gradually but steadily, the technologies involved migrated from (science) fiction into scholarly publications, and from “utopia” (or “dystopia”) into science. Building on seminal ideas borrowed from Nietzsche, Peter Sloterdijk has outlined the challenges inherent in this development. Since time immemorial, and at (...)
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  • Human Enhancement.Nick Bostrom & Julian Savulescu (eds.) - 2009 - Oxford University Press.
    To what extent should we use technological advances to try to make better human beings? Leading philosophers debate the possibility of enhancing human cognition, mood, personality, and physical performance, and controlling aging. Would this take us beyond the bounds of human nature? These are questions that need to be answered now.
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  • Health, Happiness and Human Enhancement—Dealing with Unexpected Effects of Deep Brain Stimulation.Maartje Schermer - 2011 - Neuroethics 6 (3):435-445.
    Deep Brain Stimulation (DBS) is a treatment involving the implantation of electrodes into the brain. Presently, it is used for neurological disorders like Parkinson’s disease, but indications are expanding to psychiatric disorders such as depression, addiction and Obsessive Compulsive Disorder (OCD). Theoretically, it may be possible to use DBS for the enhancement of various mental functions. This article discusses a case of an OCD patient who felt very happy with the DBS treatment, even though her symptoms were not reduced. First, (...)
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  • Procreative Beneficence: Why We Should Select the Best Children.Julian Savulescu - 2001 - Bioethics 15 (5-6):413-426.
    We have a reason to use information which is available about such genes in our reproductive decision-making; (3) couples should selec.
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  • Asymmetries in ethics.Knut Erik Tranöy - 1967 - Inquiry: An Interdisciplinary Journal of Philosophy 10 (1-4):351-372.
    Ethical notions such as good and bad, are often treated as though they were ?symmetric? in the sense of having the same moral ?weight?, one in a positive the other in a negative sense. I argue that they are in fact ?asymmetric? and that the negative members of such pairs of notions are more fundamental and definite, logically speaking, and operationally more important than the positive members. Detailed arguments are given to show this for some non?moral notions, such as life (...)
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  • Bioconservatism, Bioliberalism, and Repugnance.Rebecca Roache & Steve Clarke - 2009 - Monash Bioethics Review 28 (1):04.1-04.21.
    We consider the current debate between bioconservatives and their opponents—whom we dub bioliberals—about the moral acceptability of human enhancement and the policy implications of moral debates about enhancement. We argue that this debate has reached an impasse, largely because bioconservatives hold that we should honour intuitions about the special value of being human, even if we cannot identify reasons to ground those intuitions. We argue that although intuitions are often a reliable guide to belief and action, there are circumstances in (...)
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  • (1 other version)Human nature and enhancement.Allen Buchanan - 2008 - Bioethics 23 (3):141-150.
    Appeals to the idea of human nature are frequent in the voluminous literature on the ethics of enhancing human beings through biotechnology. Two chief concerns about the impact of enhancements on human nature have been voiced. The first is that enhancement may alter or destroy human nature. The second is that if enhancement alters or destroys human nature, this will undercut our ability to ascertain the good because, for us, the good is determined by our nature. The first concern assumes (...)
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  • (1 other version)The wisdom of nature: an evolutionary heuristic for human enhancement.Nick Bostrom & Anders Sandberg - 2009 - In Nick Bostrom & Julian Savulescu (eds.), Human Enhancement. Oxford University Press. pp. 375--416.
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  • Is there a problem with enhancement?Frances M. Kamm - 2005 - American Journal of Bioethics 5 (3):5 – 14.
    This article examines arguments concerning enhancement of human persons recently presented by Michael Sandel (2004). In the first section, I briefly describe some of his arguments. In section two, I consider whether, as Sandel claims, the desire for mastery motivates enhancement and whether such a desire could be grounds for its impermissibility. Section three considers how Sandel draws the distinction between treatment and enhancement, and the relation to nature that he thinks each expresses. The fourth section examines Sandel's views about (...)
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  • The reversal test: Eliminating status quo bias in applied ethics.Nick Bostrom & Toby Ord - 2006 - Ethics 116 (4):656-679.
    Suppose that we develop a medically safe and affordable means of enhancing human intelligence. For concreteness, we shall assume that the technology is genetic engineering (either somatic or germ line), although the argument we will present does not depend on the technological implementation. For simplicity, we shall speak of enhancing “intelligence” or “cognitive capacity,” but we do not presuppose that intelligence is best conceived of as a unitary attribute. Our considerations could be applied to specific cognitive abilities such as verbal (...)
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  • Health as a theoretical concept.Christopher Boorse - 1977 - Philosophy of Science 44 (4):542-573.
    This paper argues that the medical conception of health as absence of disease is a value-free theoretical notion. Its main elements are biological function and statistical normality, in contrast to various other ideas prominent in the literature on health. Apart from universal environmental injuries, diseases are internal states that depress a functional ability below species-typical levels. Health as freedom from disease is then statistical normality of function, i.e., the ability to perform all typical physiological functions with at least typical efficiency. (...)
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  • When is diminishment a form of enhancement? : rethinking the enhancement debate in biomedical ethics.Brian D. Earp, Anders Sandberg, Guy Kahane & Julian Savulescu - unknown
    The enhancement debate in neuroscience and biomedical ethics tends to focus on the augmentation of certain capacities or functions: memory, learning, attention, and the like. Typically, the point of contention is whether these augmentative enhancements should be considered permissible for individuals with no particular “medical” disadvantage along any of the dimensions of interest. Less frequently addressed in the literature, however, is the fact that sometimes the _diminishment_ of a capacity or function, under the right set of circumstances, could plausibly contribute (...)
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  • A Second Rebuttal On Health.Christopher Boorse - 2014 - Journal of Medicine and Philosophy 39 (6):683-724.
    This essay replies to critics since 1995 of my “biostatistical theory” of health. According to the BST, a pathological condition is a state of statistically species-subnormal biological part-functional ability, relative to sex and age. Theoretical health, the total absence of pathological conditions, is then a value-free scientific notion. Recent critics offer a mixture of old and new objections to this analysis. Some new ones relate to choice of reference class, situation-specificity of function, common diseases and healthy populations, improvements in population (...)
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  • Christopher Boorse and the Philosophy of Medicine.Thomas Schramme - 2014 - Journal of Medicine and Philosophy 39 (6):565-571.
    In 2012, the symposium "Christopher Boorse and the Philosophy of Medicine" was held at the University of Hamburg. The initial ideas presented at this event, which celebrated Chris's contribution to the development of what is now a vibrant area of research, especially to the theory of disease, form the core of the papers published in this issue. Similarly to what Robert Nozick once said about John Rawls's work, it can be demanded that philosophers of medicine must now either work within (...)
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  • Emotion, Rationality, and the “Wisdom of Repugnance”.Gregory E. Kaebnick - 2012 - Hastings Center Report 38 (4):36-45.
    Much work in bioethics tries to sidestep bedrock questions about moral values. This is fine if we agree on our values; arguments about human enhancement suggest we do not. One bedrock question underlying these arguments concerns the role of emotion in morality: worries about enhancement are derided as emotional and thus irrational. In fact, both emotion and reason are integral to all moral judgment.
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  • Reproductive Choice, Enhancement, and the Moral Continuum Argument.E. Malmqvist - 2014 - Journal of Medicine and Philosophy 39 (1):41-54.
    It is often argued that it does not matter morally whether biomedical interventions treat or prevent diseases or enhance nondisease traits; what matters is whether and how much they promote well-being. Therapy and enhancement both promote well-being, the argument goes, so they are not morally distinct but instead continuous. I provide three reasons why this argument should be rejected when it is applied to choices concerning the genetic makeup of future people. First, it rests on too simple a conception of (...)
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  • The myth of genetic enhancement.Philip M. Rosoff - 2012 - Theoretical Medicine and Bioethics 33 (3):163-178.
    The ongoing revolution in molecular genetics has led many to speculate that one day we will be able to change the expression or phenotype of numerous complex traits to improve ourselves in many different ways. The prospect of genetic enhancements has generated heated controversy, with proponents advocating research and implementation, with caution advised for concerns about justice, and critics tending to see the prospect of genetic enhancements as an assault on human freedom and human nature. Both camps base their arguments (...)
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  • The Case Against Perfection.Michael J. Sandel - 2004 - The Atlantic (April):1–11.
    What's wrong with designer children, bionic athletes, and genetic engineering.
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  • Normal Functioning and the Treatment-Enhancement Distinction.Norman Daniels - 2000 - Cambridge Quarterly of Healthcare Ethics 9 (3):309--322.
    The treatment-enhancement distinction draws a line between services or interventions meant to prevent or cure conditions that we view as diseases or disabilities and interventions that improve a condition that we view as a normal function or feature of members of our species. The line drawn here is widely appealed to in medical practice and medical insurance contexts, as well as in our everyday thinking about the medical services we do and should assist people in obtaining.
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  • Ethical issues in human enhancement.Nick Bostrom & Rebecca Roache - 2007 - In Jesper Ryberg, Thomas S. Petersen & Clark Wolf (eds.), New waves in applied ethics. New York: Palgrave-Macmillan. pp. 120--152.
    Human enhancement has emerged in recent years as a blossoming topic in applied ethics. With continuing advances in science and technology, people are beginning to realize that some of the basic parameters of the human condition might be changed in the future. One important way in which the human condition could be changed is through the enhancement of basic human capacities. If this becomes feasible within the lifespan of many people alive today, then it is important now to consider the (...)
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  • Fuzzy health, illness, and disease.Kazem Sadegh-Zadeh - 2000 - Journal of Medicine and Philosophy 25 (5):605 – 638.
    The notions of health, illness, and disease are fuzzy-theoretically analyzed. They present themselves as non-Aristotelian concepts violating basic principles of classical logic. A recursive scheme for defining the controversial notion of disease is proposed that also supports a concept of fuzzy disease. A sketch is given of the prototype resemblance theory of disease.
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  • Medicine and medicalization: A response to Purdy.Ann Garry - 2001 - Bioethics 15 (3):262–269.
    Many feminists are critical of the practices and institutions that medicalize people’s lives, especially the lives of women and other members of marginalized groups. I argue that this critique does not necessarily imply a rejection of medicine. I give a brief analysis of the concept of medicalization that supports the view that one can desire medicine without desiring medicalization. I then discuss the relations among what is considered natural, socially constructed, and medicalized.
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  • Overdiagnosis, medicalisation and social justice: commentary on Carteret al ‘A definition and ethical evaluation of overdiagnosis’.Michael Morrison - 2016 - Journal of Medical Ethics 42 (11):720-721.
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  • Cognitive Enhancement and the Principle of Need.Barbro Fröding & Niklas Juth - 2015 - Neuroethics 8 (3):231-242.
    In this article we argue that the principle of need, on some interpretations, could be used to justify the spending of publically funded health care resources on cognitive enhancement and that this also holds true for individuals whose cognitive capacities are considered normal.The increased, and to an extent, novel demands that the modern technology and information society places on the cognitive capacities of agents, e.g., regarding good and responsible decision-making, have blurred the line between treatment and enhancement. More specifically, it (...)
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  • Rethinking Nature: Public Visions in the Netherlands.Riyan J. G. Van Den Born - 2008 - Environmental Values 17 (1):83-109.
    This study addresses two questions: (1) what visions of nature do lay people subscribe to? (2) to what extent do these visions reflect those of professional philosophers? Four philosophical images of the human-nature relationship were discussed with respondents; Master, Steward, Partner and Participant. Respondents recognise these images, but prefer to construct their own. Elements of their images are (1) that humans are part of nature, but (2) that they are responsible for nature as well. This study indicates that empirical philosophy (...)
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  • Justice, Fairness, and Enhancement.Julian Savulescu - 2006 - Annals of New York Academy of Science 1093:321-338.
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  • Memory enhancing drugs and Alzheimer’s Disease: Enhancing the self or preventing the loss of it? [REVIEW]Wim Dekkers & Marcel Olde Rikkert - 2007 - Medicine, Health Care and Philosophy 10 (2):141-151.
    In this paper we analyse some ethical and philosophical questions related to the development of memory enhancing drugs (MEDs) and anti-dementia drugs. The world of memory enhancement is coloured by utopian thinking and by the desire for quicker, sharper, and more reliable memories. Dementia is characterized by decline, fragility, vulnerability, a loss of the most important cognitive functions and even a loss of self. While MEDs are being developed for self-improvement, in Alzheimer’s Disease (AD) the self is being lost. Despite (...)
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  • (1 other version)Human Nature and the Problem of Remolding Man: Marxian and Confucian.Tsung-I. Dow - 1983 - Dialectics and Humanism 10 (4):103-116.
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  • Medicalization: Current concept and future directions in a Bionic Society.Antonio Maturo - 2012 - Mens Sana Monographs 10 (1):122.
    The article illustrates the main features of the concept of medicalization, starting from its theoretical roots. Although it is the process of extending the medical gaze on human conditions, it appears that medicalization cannot be strictly connected to medical imperialism anymore. Other "engines" of medicalization are influential: consumers, biotechnology and managed care. The growth of research and theoretical reflections on medicalization has led to the proposal of other parallel concepts like pharmaceuticalization, genetization and biomedicalization. These new theoretical tools could be (...)
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  • ‘I hope that I get old before I die’: ageing and the concept of disease.Thomas Schramme - 2013 - Theoretical Medicine and Bioethics 34 (3):171-187.
    Ageing is often deemed bad for people and something that ought to be eliminated. An important aspect of this normative aspect of ageing is whether ageing, i.e., senescence, is a disease. In this essay, I defend a theory of disease that concludes that ageing is not a disease, based on an account of natural function. I also criticize other arguments that lead to the same conclusion. It is important to be clear about valid reasons in this debate, since the failure (...)
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  • Human Nature: The Very Idea.Tim Lewens - 2012 - Philosophy and Technology 25 (4):459-474.
    Abstract The only biologically respectable notion of human nature is an extremely permissive one that names the reliable dispositions of the human species as a whole. This conception offers no ethical guidance in debates over enhancement, and indeed it has the result that alterations to human nature have been commonplace in the history of our species. Aristotelian conceptions of species natures, which are currently fashionable in meta-ethics and applied ethics, have no basis in biological fact. Moreover, because our folk psychology (...)
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  • (1 other version)The Wisdom of Nature: An Evolutionary Heuristic for Human Enhancement.Anders Sandberg & Nick Bostrom - 2017 - In Dien Ho (ed.), Philosophical Issues in Pharmaceutics: Development, Dispensing, and Use. Dordrecht: Springer.
    Human beings are a marvel of evolved complexity. Such systems can be difficult to enhance. When we manipulate complex evolved systems, which are poorly understood, our interventions often fail or backfire. It can appear as if there is a “wisdom of nature” which we ignore at our peril. Sometimes the belief in nature’s wisdom—and corresponding doubts about the prudence of tampering with nature, especially human nature—manifests as diffusely moral objections against enhancement. Such objections may be expressed as intuitions about the (...)
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  • (1 other version)Normality, Therapy, and Enhancement.Alberto Giubilini - 2015 - Cambridge Quarterly of Healthcare Ethics 24 (3):347-354.
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  • One principle and three fallacies of disability studies.John Harris - 2001 - Journal of Medical Ethics 27 (6):383-387.
    My critics in this symposium illustrate one principle and three fallacies of disability studies. The principle, which we all share, is that all persons are equal and none are less equal than others. No disability, however slight, nor however severe, implies lesser moral, political or ethical status, worth or value. This is a version of the principle of equality. The three fallacies exhibited by some or all of my critics are the following: Choosing to repair damage or dysfunction or to (...)
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  • Cochlear Implantation, Enhancements, Transhumanism and Posthumanism: Some Human Questions.Joseph Lee - 2016 - Science and Engineering Ethics 22 (1):67-92.
    Biomedical engineering technologies such as brain–machine interfaces and neuroprosthetics are advancements which assist human beings in varied ways. There are exciting yet speculative visions of how the neurosciences and bioengineering may influence human nature. However, these could be preparing a possible pathway towards an enhanced and even posthuman future. This article seeks to investigate several ethical themes and wider questions of enhancement, transhumanism and posthumanism. Four themes of interest are: autonomy, identity, futures, and community. Three larger questions can be asked: (...)
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  • Health and Functional Efficiency.Daniel M. Hausman - 2014 - Journal of Medicine and Philosophy 39 (6):634-647.
    This essay argues that what is central to Christopher Boorse’s biostatistical theory of disease as statistically subnormal part function (BST) are comparisons of the “functional efficiency” of parts and processes and that statistical considerations serve only to pick out a healthy level of functional efficiency. On this interpretation, the distinction between health and pathology is less important than comparisons of functional efficiency, which are entirely independent of statistical considerations. The clarifications or revisions of the BST that this essay offers are (...)
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