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An Ontic Account of Explanatory Reduction in Biology

Köln: Kölner Hochschulschriften (2012)

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  1. When mechanistic models explain.Carl F. Craver - 2006 - Synthese 153 (3):355-376.
    Not all models are explanatory. Some models are data summaries. Some models sketch explanations but leave crucial details unspecified or hidden behind filler terms. Some models are used to conjecture a how-possibly explanation without regard to whether it is a how-actually explanation. I use the Hodgkin and Huxley model of the action potential to illustrate these ways that models can be useful without explaining. I then use the subsequent development of the explanation of the action potential to show what is (...)
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  • Aggregativity: Reductive heuristics for finding emergence.William C. Wimsatt - 1997 - Philosophy of Science 64 (4):372-84.
    Most philosophical accounts of emergence are incompatible with reduction. Most scientists regard a system property as emergent relative to properties of the system's parts if it depends upon their mode of organization--a view consistent with reduction. Emergence can be analyzed as a failure of aggregativity--a state in which "the whole is nothing more than the sum of its parts." Aggregativity requires four conditions, giving tools for analyzing modes of organization. Differently met for different decompositions of the system, and in different (...)
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  • Making sense of emergence.Jaegwon Kim - 1999 - Philosophical Studies 95 (1-2):3-36.
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  • (4 other versions)Mental Events.Donald Davidson - 2003 - In John Heil (ed.), Philosophy of Mind: A Guide and Anthology. New York: Oxford University Press.
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  • (1 other version)New Work For a Theory of Universals.David Lewis - 1997 - In David Hugh Mellor & Alex Oliver (eds.), Properties. New York: Oxford University Press.
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  • Instrumental Biology or the Disunity of Science.Alexander Rosenberg - 1997 - Philosophical Quarterly 47 (186):120-122.
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  • Reductive Explanation and the 'Explanatory Gap'.Peter Carruthers - 2004 - Canadian Journal of Philosophy 34 (2):153-173.
    Can phenomenal consciousness be given a reductive natural explanation? Exponents of an ‘explanatory gap’ between physical, functional and intentional facts, on the one hand, and the facts of phenomenal consciousness, on the other, argue that there are reasons of principle why phenomenal consciousness cannot be reductively explained: Jackson (1982), (1986); Levine (1983), (1993), (2001); McGinn (1991); Sturgeon (1994), (2000); Chalmers (1996), (1999). Some of these writers claim that the existence of such a gap would warrant a belief in some form (...)
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  • (1 other version)Causality and Explanation.Wesley C. Salmon - 1997 - New York, US: Oxford University Press USA.
    "A rich collection. Since it holds a number of introductory pieces along with advanced essays and review articles, the volume will be accessible to a broad audience and will work well in philosophy of science courses....Essential."--Lawrence Sklar, University of Michigan.
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  • Structures of Scientific Theories.Carl F. Craver - 2002 - In Peter K. Machamer & Michael Silberstein (eds.), The Blackwell guide to the philosophy of science. Malden, Mass.: Blackwell. pp. 55–79.
    This chapter contains sections titled: Introduction The Once Received View (ORV) Criticisms of the ORV The “Model Model” of Scientific Theories Mechanisms: Investigating Nonformal Patterns in Scientific Theories Conclusion.
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  • (1 other version)Constitution Is Not Identity.Mark Johnston - 1997 - In Michael Cannon Rea (ed.), Material Constitution: A Reader. Lanham, Md.: Rowman & Littlefield Publishers. pp. 44-62.
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  • Topological explanations and robustness in biological sciences.Philippe Huneman - 2010 - Synthese 177 (2):213-245.
    This paper argues that besides mechanistic explanations, there is a kind of explanation that relies upon “topological” properties of systems in order to derive the explanandum as a consequence, and which does not consider mechanisms or causal processes. I first investigate topological explanations in the case of ecological research on the stability of ecosystems. Then I contrast them with mechanistic explanations, thereby distinguishing the kind of realization they involve from the realization relations entailed by mechanistic explanations, and explain how both (...)
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  • Of molecules and men.Francis Crick - 1966 - Seattle,: University of Washington Press.
    "In his third lecture Crick anticipates events and trends that have in fact come to pass in the past four decades, including the increasing use of computer technology and robotics in mind-brain research, explorations into right-side versus left-side uses of the brain, and controversies surrounding the existence of the soul."--BOOK JACKET.
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  • How is biological explanation possible?Alex Rosenberg - 2001 - British Journal for the Philosophy of Science 52 (4):735-760.
    That biology provides explanations is not open to doubt. But how it does so must be a vexed question for those who deny that biology embodies laws or other generalizations with the sort of explanatory force that the philosophy of science recognizes. The most common response to this problem has involved redefining law so that those grammatically general statements which biologists invoke in explanations can be counted as laws. But this terminological innovation cannot identify the source of biology's explanatory power. (...)
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  • Naturalism.Davidn D. Papineau - 2007 - Stanford Encyclopedia of Philosophy.
    The term ‘naturalism’ has no very precise meaning in contemporary philosophy. Its current usage derives from debates in America in the first half of the last century. The self-proclaimed ‘naturalists’ from that period included John Dewey, Ernest Nagel, Sidney Hook and Roy Wood Sellars. These philosophers aimed to ally philosophy more closely with science. They urged that reality is exhausted by nature, containing nothing ‘supernatural’, and that the scientific method should be used to investigate all areas of reality, including the (...)
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  • Explanation in two dimensions: Diagrams and biological explanation.Laura Perini - 2005 - Biology and Philosophy 20 (2-3):257-269.
    Molecular biologists and biochemists often use diagrams to present hypotheses. Analysis of diagrams shows that their content can be expressed with linguistic representations. Why do biologists use visual representations instead? One reason is simple comprehensibility: some diagrams present information which is readily understood from the diagram format, but which would not be comprehensible if the same information was expressed linguistically. But often diagrams are used even when concise, comprehensible linguistic alternatives are available. I explain this phenomenon by showing why diagrammatic (...)
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  • (1 other version)Review of Robert N. Brandon: Concepts and Methods in Evolutionary Biology[REVIEW]John Dupré - 1997 - British Journal for the Philosophy of Science 48 (2):292-296.
    This book is a collection of essays by a leading philosopher of biology and spans his career over almost the last twenty years. Most of the topics that have been of concern to philosophers of biology in this period are touched on to some extent, and the collection of these essays in a convenient volume will certainly be welcomed by everyone working in this field. The essays are arranged chronologically, and divided into three sections. Although the chapters in the first (...)
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  • Mind, Language and Reality.Hilary Putnam - 1975/2003 - Critica 12 (36):93-96.
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  • What's Wrong with Microphysicalism?Andreas Hüttemann - 2003 - New York: Routledge.
    'Microphysicalism', the view that whole objects behave the way they do in virtue of the behaviour of their constituent parts, is an influential contemporary view with a long philosophical and scientific heritage. In _What's Wrong With Microphysicalism?_ Andreas Hüttemann offers a fresh challenge to this view. Hüttemann agrees with the microphysicalists that we can explain compound systems by explaining their parts, but claims that this does not entail a fundamentalism that gives hegemony to the micro-level. At most, it shows that (...)
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  • Thinking again about biological mechanisms.Lindley Darden - 2008 - Philosophy of Science 75 (5):958-969.
    The new research program to understand mechanisms in biology has developed rapidly in the last 10 years. Reconsideration of the characterization of mechanisms in biology in the light of this recent work is now in order. This article discusses the perspectival aspect of the characterization of mechanisms, refinements in claims about working entities and kinds of activities, challenges and responses to claims about regularity, productive continuity, and the organizational aspects of a mechanism, and issues about representations of mechanisms in schemas (...)
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  • Natural laws in scientific practice.Marc Lange - 2000 - New York: Oxford University Press.
    It is often presumed that the laws of nature have special significance for scientific reasoning. But the laws' distinctive roles have proven notoriously difficult to identify--leading some philosophers to question if they hold such roles at all. This study offers original accounts of the roles that natural laws play in connection with counterfactual conditionals, inductive projections, and scientific explanations, and of what the laws must be in order for them to be capable of playing these roles. Particular attention is given (...)
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  • Philosophy of Biology in Britain. [REVIEW]Paul Griffiths - 2007 - Metascience 16:535-537.
    The Royal Institute of Philosophy’s London lecture series for 2004–2005 offers a useful snapshot of the current state of philosophy of biology in Britain. With one or two exceptions the papers are not simply current research articles. The authors map out questions they feel need more research, analyse ongoing debates, or outline the program of their own previously published work. This presumably reflects the fact that the papers are based closely on public lectures. It also makes for surprisingly easy and (...)
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  • Probability, explanation, and information.Peter Railton - 1981 - Synthese 48 (2):233 - 256.
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  • Unification as a regulative ideal.Philip Kitcher - 1999 - Perspectives on Science 7 (3):337-348.
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  • (1 other version)Natural Laws in Scientific Practice.John W. Carroll - 2005 - Philosophy and Phenomenological Research 71 (1):240-245.
    This is a review of Marc Lange's _Natural Laws in Scientific Practice<D>.
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  • Explaining Science.Ronald Giere - 1991 - Noûs 25 (3):386-388.
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  • (1 other version)Constitutive Explanatory Relevance.Carl Craver - 2007 - Journal of Philosophical Research 32:3-20.
    In what sense are the activities and properties of components in a mechanism explanatorily relevant to the behavior of a mechanism as a whole? I articulate this problem, the problem of constitutive relevance, and I show that it must be solved if we are to understand mechanisms and mechanistic explanation. I argue against some putative solutions to the problem of constitutive relevance, and I sketch a positive account according to which relevance is analyzed in terms ofrelationships of mutual manipulability between (...)
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  • Scientific Explanation and the Causal Structure of the World.Ronald N. Giere - 1988 - Philosophical Review 97 (3):444.
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  • Biological Complexity and Integrative Pluralism.Sandra D. Mitchell - 2003 - Cambridge University Press.
    This fine collection of essays by a leading philosopher of science presents a defence of integrative pluralism as the best description for the complexity of scientific inquiry today. The tendency of some scientists to unify science by reducing all theories to a few fundamental laws of the most basic particles that populate our universe is ill-suited to the biological sciences, which study multi-component, multi-level, evolved complex systems. This integrative pluralism is the most efficient way to understand the different and complex (...)
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  • Reduction in Genetics.Michael Ruse - 1974 - PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1974:633 - 651.
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  • Scientific Explanation.Philip Kitcher & Wesley C. Salmon (eds.) - 1962 - Univ of Minnesota Pr.
    Studdert-Kennedy, Gerald, Evidence and Explanation in Social Science. ... Kauffman, Stuart, "Articulation of Parts Explanation in Biology and the Rational ...
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  • Reductive Explanation: A Functional Account.William C. Wimsatt - 1972 - PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association 1974:671-710.
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  • Reductionism redux: Computing the embryo. [REVIEW]Alex Rosenberg - 1997 - Biology and Philosophy 12 (4):445-470.
    This paper argues that the consensus physicalist antireductionism in the philosophy of biology cannot accommodate the research strategy or indeed the recent findings of molecular developmental biology. After describing Wolperts programmatic claims on its behalf, and recent work by Gehring and others to identify the molecular determinants of development, the paper attempts to identify the relationship between evolutionary and developmental biology by reconciling two apparently conflicting accounts of bio-function – Wrights and Nagels (as elaborated by Cummins). Finally, the paper seeks (...)
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  • Process causality and asymmetry.Phil Dowe - 1992 - Erkenntnis 37 (2):179-196.
    Process theories of causality seek to explicate causality as a property of individual causal processes. This paper examines the capacity of such theories to account for the asymmetry of causation. Three types of theories of asymmetry are discussed; the subjective, the temporal, and the physical, the third of these being the preferred approach. Asymmetric features of the world, namely the entropic and Kaon arrows, are considered as possible sources of causal asymmetry and a physical theory of asymmetry is subsequently developed (...)
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  • Review of M aking Things Happen. [REVIEW]Eric Hiddleston - 2005 - Philosophical Review 114 (4):545-547.
    Woodward's long awaited book is an attempt to construct a comprehensive account of causation explanation that applies to a wide variety of causal and explanatory claims in different areas of science and everyday life. The book engages some of the relevant literature from other disciplines, as Woodward weaves together examples, counterexamples, criticisms, defences, objections, and replies into a convincing defence of the core of his theory, which is that we can analyse causation by appeal to the notion of manipulation.
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  • Critical Notice: D arwinian Reductionism.Marcel Weber - 2008 - Biology and Philosophy 23 (1):143-152.
    This notice provides a critical discussion of some of the issues from Alex Rosenberg’s Darwinian Reductionism, in particular proper functions and the relationship of proximate and ultimate biology, developmental programs and genocentrism, biological laws, the principle of natural selection as a fundamental law, genetic determinism, and the definition of “reductionism.”.
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  • (1 other version)The Scientific Image by Bas C. van Fraassen. [REVIEW]Michael Friedman - 1982 - Journal of Philosophy 79 (5):274-283.
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  • A Modified Conception of Mechanisms.Phillip J. Torres - 2009 - Erkenntnis 71 (2):233-251.
    In this paper, I critique two conceptions of mechanisms, namely those put forth by Stuart Glennan (Erkenntnis 44:49–71, 1996; Philosophy of Science 69:S342–S353, 2002) and Machamer et al. (Philosophy of Science 67:1–25, 2000). Glennan’s conception, I argue, cannot account for mechanisms involving negative causation because of its interactionist posture. MDC’s view encounters the same problem due to its reificatory conception of activities—this conception, I argue, entails an onerous commitment to ontological dualism. In the place of Glennan and MDC, I propose (...)
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  • The Structure of Scientific Theories.Mario H. Otero - 1979 - Philosophy and Phenomenological Research 40 (1):148-150.
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  • Review of Scientific Explanation and the Causal Structure of the World. [REVIEW]James Woodward - 1988 - Noûs 22 (2):322-324.
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  • (1 other version)The Structure of Biological Science.John Dupré - 1986 - Philosophy of Science 53 (3):461-463.
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  • Wholes, sums, and organic unities.Ernest Nagel - 1952 - Philosophical Studies 3 (2):17 - 32.
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  • Concepts and Methods in Evolutionary Biology.Robert N. Brandon - 1995 - Cambridge University Press.
    Robert Brandon is one of the most important and influential of contemporary philosophers of biology. This collection of his recent essays covers all the traditional topics in the philosophy of evolutionary biology and as such could serve as an introduction to the field. There are essays on the nature of fitness, teleology, the structure of the theory of natural selection, and the levels of selection. The book also deals with newer topics that are less frequently discussed but are of growing (...)
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  • The hegemony of molecular biology.Philip Kitcher - 1999 - Biology and Philosophy 14 (2):195-210.
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  • Molecular biology and the unity of science.Harold Kincaid - 1990 - Philosophy of Science 57 (4):575-593.
    Advances in molecular biology have generally been taken to support the claim that biology is reducible to chemistry. I argue against that claim by looking in detail at a number of central results from molecular biology and showing that none of them supports reduction because (1) their basic predicates have multiple realizations, (2) their chemical realization is context-sensitive and (3) their explanations often presuppose biological facts rather than eliminate them. I then consider the heuristic and confirmational implications of irreducibility and (...)
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  • Reduction in Genetics—Biology or Philosophy?David L. Hull - 1972 - Philosophy of Science 39 (4):491-499.
    A belief common among philosophers and biologists alike is that Mendelian genetics has been or is in the process of being reduced to molecular genetics, in the sense of formal theory reduction current in the literature. The purpose of this paper is to show that there are numerous empirical and conceptual difficulties which stand in the way of establishing a systematic inferential relation between Mendelian and molecular genetics. These difficulties, however, have little to do with the traditional objections which have (...)
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  • (4 other versions)The Cement of the Universe.John Earman & J. L. Mackie - 1976 - Philosophical Review 85 (3):390.
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  • Physical law and mechanistic explanation in the Hodgkin and Huxley model of the action potential.Carl F. Craver - 2008 - Philosophy of Science 75 (5):1022-1033.
    Hodgkin and Huxley’s model of the action potential is an apparent dream case of covering‐law explanation in biology. The model includes laws of physics and chemistry that, coupled with details about antecedent and background conditions, can be used to derive features of the action potential. Hodgkin and Huxley insist that their model is not an explanation. This suggests either that subsuming a phenomenon under physical laws is insufficient to explain it or that Hodgkin and Huxley were wrong. I defend Hodgkin (...)
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  • Hempel’s Ambiguity.J. Alberto Coffa - 1974 - Synthese 28 (2):141 - 163.
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  • (1 other version)Philosophy of Mind.Alex Byrne & Jaegwon Kim - 1998 - Philosophical Review 107 (1):113.
    In the preface, Kim writes hopefully that his introduction to the philosophy of mind is “intended to be accessible to those without a formal background in philosophy”. The blurb at the end is more realistic: Philosophy of Mind is “a textbook for upper-level undergraduates and graduate students”. It is an admirable addition to Westview’s excellent Dimensions of Philosophy series. Brisk, workmanlike chapters profile the usual suspects: behaviorism, the identity theory, mind as computer and as causal structure, mental causation, consciousness, mental (...)
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  • The British Journal for the Philosophy of Science | Vol 73, No 3.John Dupré - 1996 - Cambridge University Press.
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