The hidden brain has its finger on the scale when we make all of our most complex and important decisions – it decides who we fall in love with, whether we should convict someone of murder, or which way to run when someone yells “fire ...

This article discusses the Philosophical and Regulatory mappings of Brain Control Interfaces in the coming age of Trans-humans. The author combines perspectives from Material Engagement theory, Don Ihde’s post-phenomenological perspective and Veerback’s cyborg intentionality on human-technology relations and juxtaposes this post-phenomenological hybrid-intentionality on upcoming BCI such as Neuralink. Taking the hybrid-intentionality as point of departure, the author then develops Regulatory approaches and principles in context of the normative harms borne out of such transfiguration while also highlighting these key harms.

Fake news is a topic that we all know well, and that continues to play a prominent role in the social harms besieging the globe today. From the recent storming of the Capitol Hill in the United States to the siege of Red fort over Farm-laws in India, online disinformation via social media platforms was the main driving force catapulting the protestors far and wide. In the backdrop of such social harms, this Research Article examines the epistemic, legal and regulatory (...) discourse surrounding the disinformation bubble in India and asks for the deployment of ‘Lessig’s Decentred Regulatory Model’ — the potential Framework solution to regulate social media platforms in order to curb the menace of ‘fake news’. (shrink)

Michael Smith’s Internalist resolution to “The Moral Problem” serves to establish a necessary connection between moral judgement and moral motivation in the rational agent. Externalists, like Brink, counter Smith’s claim with the figure of the Amoralist, whose moral motivation, they argue, is only contingent on antecedently-held desires. In this paper, I draw a distinction between “moral motivation” – if an agent judges it right to Φ, she is, ceteris paribus, motivated to Φ - and “acting on moral motivation” – if (...) an agent judges it right to Φ, she actually Φs. I show how the Amoralist explanation might account for the latter, but not the former, which ultimately leaves Smith’s argument for motivational Internalism intact. (shrink)

The fear of the unknown is the lived reality of the handloom industry in India. Handloom is the second largest employment provider in the country, after agriculture. According to the 2019-20 National Census of Handloom Weavers, there are 31.44 lakh households engaged in weaving and allied activities, out of which 87% are in rural areas. The objective of this article is to study the social enterprises that are looking for innovative ways to receive the handloom sector in the post-pandemic period. (...) Further its aim to study the digital impact on the handloom sector, especially on women. (shrink)

So what does understanding mean? When understanding of life happens to man based on cause, effect and time, it is incomplete. They are the knowledgeable. And when understanding happens to man that life is not based on cause effect and time, it is complete. They are the wise or Sages.

Math literacy is miniscule compared to the near universal language literacy of mother tongues. Our search for the root cause of this undesirable human condition led us to: Grammar (or the abstract essence) of a language. Language learning begins with grammar, unless the language happens to be mathematics, which is unique in not even considering including the grammar (abstract general/theory) of mathematics in the mathematical pedagogy. Here we make a case for introducing the abstract essence of mathematics--Conceptual Mathematics--in high school (...) math curriculum. Recognizing that the singular purpose of education is to nurture the universal yearning for understanding, we show how a nurturing pedagogy naturally resolves the "learning crisis", with the solution manifesting as human development. Furthermore, the nurturing pedagogy that we advocate invariably results in the culture of research excellence. (shrink)

Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging studies for meta-analysis, or generating new hypotheses. To promote these goals, the ImmPort data repository was created for the broader research community to explore the wide spectrum of clinical and basic research data and associated findings. The ImmPort ecosystem consists of four components–Private Data, Shared Data, Data (...) Analysis, and Resources—for data archiving, dissemination, analyses, and reuse. To date, more than 300 studies have been made freely available through the ImmPort Shared Data portal , which allows research data to be repurposed to accelerate the translation of new insights into discoveries. (shrink)

The public health crisis is started with emergence of new coronavirus on 11 February 2020 which triggered as coronavirus disease-2019 (COVID-19) pandemics. The causative agent in COVID-19 is made up of positively wrapped single-stranded RNA viruses ~ 30 kb in size. The epidemiology, clinical features, pathophysiology, and mode of transmission have been documented well in many studies, with additional clinical trials are running for several antiviral agents. The spreading potential of COVID-19 is faster than its two previous families, the severe (...) acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV). Apart from clinical manifestation, comorbid status is playing key role for prevalence of COVID-19 infection and mortalities. The comorbid effects associated with COVID-19 are diabetes, cardiovascular, digestive, hepatitis-B, cerebrovascular, hypertension, liver injury, coronary heart disease, cancer, rheumatoid arthritis, and neurological impairment. Antimalarial drugs (chloroquine and hydroxychloroquine), remdesivir, Tocilizumab, clopinavir/ritonavir, convalescent plasma therapy, spike protein-angiotensin-converting enzyme 2 (ACE2) inhibitors, human monoclonal antibodies, mRNA-1273, mesenchymal stem cells, Indian and Chinese traditional medicine, small molecules antioxidant, natural products and dietary supplements, high doses of vitamin-E, -C, -D, minerals, flavonoids,and IFN-beta are therapeutic intervention running to develop treatment against COVID-19. Although clinical usage of these therapeutic agents against COVID-19 is well documented, cytokine storms, absence of appropriate animal model have limited its therapeutic use. This review explores the clinical information currently available on COVID-19 on the mechanisms of infection, prevention, management, comorbid status, and current drug treatment options. (shrink)