Recreational Drugs European Network (ReDNet) project aims to use the Psychonaut Web Mapping Project database (Psychonaut Web Mapping Group, 2009) containing novel psychoactive compounds usually not mentioned in the scientific literature and thus unknown to clinicians as a unique source of information. The database will be used to develop an integrated ICT prevention approach targeted at vulnerable individuals and focused on novel synthetic and herbal compounds and combinations. Particular care will be taken in keeping the health professionals working directly with (...) young people showing problematic behaviors regularly updated in terms of novel compounds and combinations as well. A user-friendly project website will be developed aimed primarily at delivering the information/prevention approaches, but will also be a way of communicating with project partners and relevant stakeholders (e.g. thematic forum facilities, instant messages, blogs, video chat, wikiblog, newsletters distributed via mailing list). The website will support various ICT prevention tools, including an SMS alert service. Different areas and sections will be aimed specifically at the different target groups. -/- . (shrink)

A new interpretation of Hegel's reading of Sophocles's Antigone, focussing on Antigone's urge to action grounded in her religious feeling, on her facing the risk of death and the consequences of this move for her sense of self-awareness, becoming also conscious of her onesidedness in respect to Creon's (equally onesided) reasons.

Risk is an intrinsic part of our lives. In the future, the development and growth of the Internet of things allows getting a huge amount of data. Considering this evolution, our research focuses on developing a novel concept, namely Holistic Risk Assessment (HRA), that takes into consideration elements outside the direct influence of the individual to provide a highly personalized risk assessment. The HRA implies developing a methodology and a model. This paper is related to the epistemological positioning of this (...) research. We consider this research as an artificial science under the constructivism paradigm. We also introduce the positioning of this research in the complexity science paradigm. We end this paper by presenting a methodology based on an adapted Design Thinking Model. (shrink)

Epileptogenesis involves an increase in excitatory synaptic strength in the brain in a manner similar to synaptic potentiation. In the present study we investigated the mechanisms of short-term synaptic potentiation in patients with focal epilepsy by using 5 Hz repetitive transcranial magnetic stimulation (rTMS), a non invasive neurophysiological technique able to investigate the mechanisms of synaptic plasticity in humans. Ten patients with focal idiopathic cortical epilepsy were studied. 5 Hz-rTMS (10 stimuli-trains, 120% of motor threshold, RMT) was delivered over the (...) first dorsal interosseus (FDI) motor area of both (affected and unaffected) hemispheres. Changes in the motor evoked potential (MEP) size in the FDI muscle during the trains and the RMT were measured and compared between the hemispheres. 5 Hz-rTMS was also delivered in a group of healthy subjects over both hemispheres. 5 Hz-rTMS in patients elicited a reduced MEP facilitation compared to normal subjects. The reduced MEP amplitude was more evident in the affected hemisphere than in the unaffected hemisphere. RMT in the affected hemisphere was higher than in the unaffected hemisphere and in healthy subjects. Our findings showing a decreased response to 5 Hz-rTMS over the affected hemisphere, differently from the expected results suggest a reduced cortical excitability in epileptic patients. We hypothesize an altered balance between excitatory and inhibitory circuits in epileptic patients under chronic therapy. (shrink)

El texto Feminism for the 99% A Manifesto, es la caracterización de un feminismo anticapitalista que considera imprescindible erigir vı́nculos con el marxismo, antirracismo, ambientalismo, derechos de los obreros y migrantes. Lo anterior busca distanciarse de posturas como el “feminismo liberal” cuya estrategia es la incorporación de la mitad de las mujeres de elite a altos cargos de las compañı́as, lo cual es criticado por las autoras, ya que no involucra un “feminismo de las masas” (de ahı́ el 99%), sino (...) de una minorı́a de mujeres privilegiadas. El libro contiene once tesis que identifican la crisis del capitalismo como origen de las problemáticas actuales y un epı́logo que consta a su vez de cinco partes, en donde se proponen las soluciones a tales problemáticas. (shrink)

Rad se bavi temom tiranije u Platonovoj filozofiji koja je neraskidivno vezana za Platonovu kritiku demokratije. Stoga, da bi se uopšte moglo govoriti o njegovoj kritici tiranije, u radu će biti prikazana i sva druga društvena uređenja koja on pominje i čija smjenjivanja bivaju odslikana kroz živopisnu paralelu smjene generacija. Izložiću njegov argument zašto su tiranin i tiranija u potpunom opozitu sa njegovom idealnom državom i kraljem filozofom, ali takođe i postaviti mnogobrojna ključna pitanja koja će u radu biti podijeljena (...) u pet cjelina. U prvoj i drugoj cjelini ću govoriti o onome što dovodi do same promjene društvenih uređenja u Platonovoj „Državi“, stavljajući akcenat na prelaz demokratije u tiraniju. U trećem dijelu biće prikazan dopadljivi početak tiranije, da bi potom u četvrtom dijelu bilo riječi o već sasvim uspostavljenoj tiraniji i onome što prof. dr Irina Deretić naziva „povlačenje logosa ili psihopatologija nepravednog tiranina“. Peti dio će poslužiti kao osvrt na razmišljanje o tome da tiranina možda treba i sažaljevati, kako i sam Sokrat govori, a zatim i razmatranje teze Čincia Aruze (engl. Cinzia Arruzza) da je Platonova kritika tiranije zapravo njegova kritika demokratije. (shrink)