In Vietnam, regionalisation in the GMS occurs in different parts at different paces and levels driven by the central government and with the participation of the local governments, private sector and grassroots people in the framework of the GMS Program. So far there has been no major research either in Vietnamese or English that addresses this issue. The thesis seeks to fill this gap by examining the empirical process of regionalisation in three Vietnam’s border towns in the First-Generation GMS Economic (...) Corridor Town Development Project. Employing analytical framework based on relevant International Relations and interdisciplinary theories, and a mix of qualitative and quantitative methods, the thesis finds that the GMS regionalisation is a combination of ‘top-down’ and ‘bottom-up’ processes. The thesis commences by highlighting the significance of the Mekong River to the development of the region. Then various multilateral cooperative schemes are explored to generate a complete picture of regional cooperation. It is concluded that many multilateral mechanisms with little progress may have negative impacts on the regionalisation in the GMS. Among 13 schemes in the GMS, GMS Program is considered as one of the most well-known subregional cooperation schemes. The GMS Program came to existence just in time to assist the Mekong riparian states to integrate better into the regional and international markets in the context that there were new developments both at the regional and world’s levels. In the case of Vietnam, the GMS Program has given Hanoi an option to carry on its omni-directional foreign policy and helped it consolidate its existing relationships with its traditional and neighbouring partners. Notably, regionalisation is occurring in some parts of the country where GMS projects have been implemented. Regionalisation can be best observed in economic space where there are intensive interactions among people under various dimensions enabled by favourable policies. Although regionalisation promises to bring new cooperative opportunities in the GMS, regionalisation in the GMS will continue to meet new challenges from growing natural and man-made threats to the Mekong River. Further, the involvement of outsiders is also a real challenge to the regionbuilding process. (shrink)

Il contenuto dei paragrafi conclusivi della "Genealogia della morale" può essere considerato il nucleo di una rete di concetti che costituisce l’intelaiatura della tarda filosofia di Nietzsche. In questo saggio si mostrerà in particolare come la problematizzazione della verità annunciata in GM III, 24 e 27 rappresenti per Nietzsche un passaggio fondamentale per portare a maturazione le istanze critiche del proprio pensiero e permettere la realizzazione della «filosofia dell’avvenire» di cui "Al di là del bene e del male" doveva costituire (...) il preludio. (shrink)

A current advance within the agricultural industry is the use of genetic engineering to produce novel crops for food production. This technology raises questions about how societies should position themselves with respect to genetically modified (GM) crop development and implementation; namely, how should the potentials and risks of this technology be evaluated? We argue that current methods to evaluate the risks and benefits of GM crops are inadequate and not conducive to the strategic development of this technology, where a way (...) to ameliorate technology assessments for GM crops is to include farmers in the research process of evaluating these crops prior to their commercialization. However, particularities concerning the ethical status of such research require special consideration and vigilance. For example, in such technology assessment initiatives, farmers would occupy both the roles of research participant and research investigator. Other particularities surface due to factors related to the nature of GM crops. These particularities are examined with reference to concepts drawn from the field of research ethics, namely informed consent, compensatory decisions, and issues of participant inclusion/exclusion. (shrink)

Gary Comstock considers whether it is ethically justified to pursue genetically modified (GM) crops and foods. He first considers intrinsic objections to GM crops that allege that the process of making GMOs is objectionable in itself. He argues that there is no justifiable basis for the objections — i.e. GM crops are not intrinsically ethically problematic. He then considers extrinsic objections to GM crops, including objections based on the precautionary principle, which focus on the potential harms that may result from (...) the adoption of GM organisms. He argues that these concerns have some merit. However, they do not justify giving up GM crops altogether. Instead, they require that GM crops be developed carefully and with appropriate oversight. Comstock then presents the positive case for GM crops that he endorses. It is based on three considerations: (i) the right of people to choose to adopt GM technology; (ii) the balance of likely benefits over harms to consumers and the environment from GM technology; and (iii) the wisdom of encouraging discovery, innovation, and careful regulation of GM technology. (shrink)

The primary responsibility of the US Food and Drug Administration is to protect public health by ensuring the safety of the food supply. To that end, it sometimes conducts risk assessments of novel food products, such as genetically modified food. The FDA describes its regulatory review of GM food as a purely scientific activity, untainted by any normative considerations. This paper provides evidence that the regulatory agency is not justified in making that claim. It is argued that the FDA’s policy (...) stance on GM food is shaped by neoliberal considerations. The agency’s review of a genetically engineered animal, the AquAdvantage salmon, is used as a case study to track the influence of neoliberalism on its regulatory review protocol. After that, an epistemic argument justifying public engagement in the risk assessment of new GM food is outlined. It is because risk evaluations involve normative judgments, in a democracy, layperson representatives of informal epistemic communities that could be affected by a new GM food should have the opportunity to decide the ethical, political or other normative questions that arise during the regulatory review of that entity. (shrink)

Some Radical New Ideas About Consciousness Consciousness and the Cosmos: A New Copernican Revolution -/- Consciousness is our new frontier in modern science. Most scientists believe that it can be accomodated, explained, by existing scientific principles. I say that it cannot. That it calls all existing scientific principles into question. That consciousness is to modern science just exactly what light was to classical physics: All of our fundamental assumptions about the nature of Reality have to change. And I go on, (...) in this work,to spell out a whole new view of Reality, and of the Universe. -/- And so, we'll have some fun! -/- Modern science is already in deep trouble... -/- Lorna Green. (shrink)

The second essay of Nietzsche's Genealogy of Morality (GM) offers a naturalistic and developmental account of the emergence of conscience, a faculty uniquely responsive to remembering and honoring obligations. This article attempts to solve an interpretive puzzle that is invited by the second essay's explanation of nonmoral obligation, prior to the capacity to feel guilt. Ostensibly, Nietzsche argues that the conscience and our concept of obligation originated within contractual (“creditor-debtor”) relations, when creditors punished delinquent debtors (GM II:5). However, this interpretation, (...) which I call the contractualist reading, is incoherent and subject to an insoluble bootstrapping problem. I argue instead that Nietzsche provides two accounts of nonmoral obligation in the second essay, and that the conscience originated in the morality of custom to track rule prohibitions (“I will nots” [GM II:3]), which Nietzsche conceives of as involuntary or reciprocal obligations that, unlike contractual debts, do not require the making of promises. (shrink)

Turkish Epistemoloji rasyonel inançların felsefi analizini konu edinmesi nedeniyle gerekçelendirme edimine merkezi bir önem atfeder. Gerekçelendirme kişinin bir önermeye inanmak için gerekçeye sahip olunmasını sağlayan koşul veya koşullar dizisinin tespit edilmesini içerir. İnançlarımızın birçoğunun çıkarımsal olmayan gerekçelerinin bulunduğu şeklindeki ılımlı/yanılırcı temelci perspektifle uyum sağlayan bir gerekçelendirme teorisi olarak Michael Huemer tarafından ortaya konan görüngüsel muhafazakarlık ilkesi, bu türden bir koşulu tanımlar. GM formülasyonuna göre eğer S’ye p olarak görünüyorsa, çürütücü etmenlerin yokluğunda S’nin p’ye inanmak için en azından bir dereceye kadar (...) gerekçesi vardır. Görüngüler ise rasyonel inanç oluşturmanın olanağına referans veren, inanç ve inanma eğilimlerinden farklı, sui generis deneyimlerdir. Bu makalede görüngülerin doğasından hareketle GM’yi tanıttım ve GM’ye yöneltilen eleştirilerin bir bölümünü tartıştım. Yer verdiğim eleştiriler, GM’nin irrasyonel/tehlikeli görüngüler ve bilişsel nüfuzdan kaynaklanan inançları dahi gerekçelendirilmiş kabul ettiği, GM teorisyenlerinin görüngülere gerekçelendirme edimi özelinde biçtiği başat rolün ve inanç ve görüngüler arasında öngörülen farklılıkların abartılı olduğu itirazlarını içerir. Bana göre sözü edilen eleştirilerin hiçbiri, GM’nin reddedilmesini gerektiren argümanlar içermez. Görüngülerin epistemik gerekçelendirmedeki rolünü tesis eden GM veya benzeri bir ilkeyi kabul etmek için temel neden ise bunun şüphecilik haricindeki olası alternatiflerinin belirsizliğidir. Çünkü eğer görüngüler, inanç oluşturmada epistemik faile rehberlik edecek göstergeler ise bu, failin ilgili göstergelerden yoksun olduğunda herhangi bir şeye rasyonel olarak inanmasının olanaksızlaşacağı anlamına gelir. English Because epistemology deals with the philosophical analysis of rational beliefs, it assigns central importance to justification. Justification involves identifying the condition or set of conditions that enables one to have grounds for believing a proposition. The principle of phenomenal conservatism, put forward by Michael Huemer as a justification theory that accords with the moderate/fallibilist foundationalist perspective that many of our beliefs have non- inferential justifications, is a principle that defines such a condition. According to the PC formulation, if it seems to S that p, then, in the absence of defeaters, S thereby has at least some degree of justification for believing that p. Seemings/appearances are sui generis experiences that refer to the possibility of rational belief formation and are different from beliefs and dispositions to believe. In this article, I introduce PC based on the nature of seemings and evaluate some of the criticisms directed at PC. The criticisms I discuss include objections that PC even justifies beliefs stemming from irrational/dangerous seemings and cognitive penetration, and that the dominant role that PC theorists assign to seemings in the act of justification and the differences envisaged between beliefs and seemings are exaggerated. In my opinion, none of these criticisms contain arguments that would lead to the rejection of PC. The main reason to accept PC or a similar principle that establishes the role of seemings in epistemic justification is the vagueness of its possible alternatives other than skepticism. For, if seemings are indicators that guide the epistemic agent in forming beliefs, this means that it is impossible for the agent to believe anything rationally when she lacks the relevant indicators. (shrink)

Agricultural biotechnology refers to a diverse set of industrial techniques used to produce genetically modified foods. Genetically modified (GM) foods are foods manipulated at the molecular level to enhance their value to farmers and consumers. This book is a collection of essays on the ethical dimensions of ag biotech. The essays were written over a dozen years, beginning in 1988. When I began to reflect on the subject, ag biotech was an exotic, untested, technology. Today, in the first year of (...) the millenium, the vast majority of consumers in the United States have taken a bite of the apple. Milk produced by cows injected with a GM protein called recombinant bovine growth hormone (bGH), is found, unlabelled, on grocery shelves throughout the US. In 1999, half of the soybeans and cotton harvested in the US were GM varieties. Billions of dollars of public and private monies are being invested annually in biotech research, and commercial sales now reach into the tens of billions of dollars each year. Whereas ag biotech once promised to change American agriculture, it now is in the process of doing so. (shrink)

Nietzsche’s late writings present a value opposition of health and decadence based in his conception of organic life. While this appears to be a moral ideal that risks the naturalistic fallacy of directly deriving norms from facts, it instead describes a meta-ethical ideal: the necessary conditions for any kind of moral agency. Nietzsche’s ideal of health not only evades but also dissolves the naturalistic fallacy by suggesting that the specific content of morality is irrelevant. If health is measured by power (...) over one’s drives rather than the environment, then the source of moral conflict—organic life’s essential tendency toward domination—is surmounted by successful integration of any moral norms, regardless of content. Nietzsche’s concept of health draws on his characterization of organic life as essentially ‘exploitation’: growth through domination of the environment (BGE 259, GM II: 12). In animals, power coincides with happiness, while health and decadence track the correspondence between instinct and happiness (TI II: 11). This simple picture is complicated by the Genealogy, where Nietzsche depicts human nature as an animal illness caused by civilization’s disruption of the natural correspondence of instinct and happiness. Civilization shapes this ‘sick animal’ into the distinctly human ‘sovereign individual’ (GM III: 13, II: 2), restoring the harmony of instinct and happiness in an internal hierarchy of drives. So, sovereign individuality is a distinctly human model of health. Although life is exploitation, human health does not coincide with greater environmental power, but rather an internal qualitative expansion of power: greater variety and tension among drives, greater ‘wholeness in diversity’ in the ‘social structure’ of the self (BGE 212, 12). Nonetheless, health is not a moral criterion, but instead the precondition of moral agency. The subordination of drives to a commanding hierarchy grounds the ability to uphold any moral principles at all, to make and keep promises to oneself and others. Moral agency coincides, in turn, with overcoming the source of moral conflict in organic life’s drive for growth. The unification of opposing drives provides pleasure in power over oneself rather than one’s environment, the ‘happiness of high tension’ among drives (BGE 260), and in environmental resistance, a need for ‘equal opponents’ (TI IX: 38, EH 1: 7). Consequently, Nietzsche’s meta-ethical ideal supports a moral pluralism that supports any moral content. Moral conflicts arise precisely to the degree individuals are incapable of achieving moral agency, but they dissolve as moral agency of any kind is more widely achieved. (shrink)

The first essay of Nietzsche’s On the Genealogy of Morals seeks to uncover the roots of Judeo-Christian morality, and to expose it as born from a resentful and feeble peasant class intent on taking revenge upon their aristocratic oppressors. There is a broad consensus in the secondary literature that the ‘slave revolt’ which gives birth to this morality occurs in the 1st century AD, and is propogated by the inhabitants of Roman occupied Judea. Nietzsche himself strongly suggests such a view. (...) However, in a telling later passage from Ecce Homo, Nietzsche claims that the hsitorical Zarathustra—a Bronze age iranian religious thinker—was the first to consider the opposite of Good vs. Evil; that “Zarathustra created this most fateful of errors, morality” (EH, 'Destiny', §3). However, Nietzsche does not discuss Zarathustra or Zoroastrianism in his critique of moral values and their origin. This creates a prima facie tension. If at least part of what essentially characterises 'morality' preceded Judeo-Christianity, are moral values only contingently related to the feelings of ressentiment essential to Nietzsche’s story of the slave revolt? If the answer is 'yes', then the scope of Nietzsche's critique of morality may be somewhat limited. If the answer is 'no', then we require an answer as to why Nietzsche's genealogy—if it is an exercise in ascertaining the “real history of morality” (GM, Pref: §7)—does not extend further back in history. In this paper, I explore how the extent of Nietzsche's knowledge of Zoroastrianism informs his critique of slave morality in On the Genealogy of Morals. I argue that Nietzsche views the historical Zarathustra—like Socrates and Plato—as a forerunner of ‘morality’ in his creative conception of good and evil in metaphysical terms. From here, it is argued that the proposed tension can be dissolved by viewing Judeo-Christian morality merely as the latest and paradigmatic expression of slave morality. (shrink)

Abstract: Retama raetam (RR) is a traditional medicinal plant belongs to fabaceae family which grows in North Africa and East Mediterranean region. Locally, RR is used in several diseases including diabetes mellitus and hypertension. Thus, this study aims to investigate certain behavioral and central effects of methanolic extract of RR seeds in experimental animals (male Albino adult mice of 20 – 35 gm). Three exploratory behavioral models are used in this study, open field, elevated plus maze and light-dark box models, (...) in addition, picrotoxin induced seizure model in mice. In elevated plus-maze test of anxiety, a dose of 25 mg/kg of RR induced a significant increase in number of open arms entries and time spent on open arms of the maze compared to the control. In light-dark model, time spent on light area and number of light-dark transitions are significantly increased after treatment with 25 mg/kg RR extract of seeds. Open field model also revealed a significant increase in general motor activity of the mouse after 25 mg/kg of RR. On the other hand, a dose of 50 mg/kg of RR significantly induced a profound central and peripheral analgesic responses. In summary, this study concludes that RR seeds have a profound anxiolytic-like effect and analgesic response with delay in latency time of seizure induced by picrotoxin in mice. (shrink)

A focus on the presence of unjustified coercion is one of the central normative concerns of Kant’s entire practical philosophy, from the ethical to the cosmopolitical. This focus is intimately interconnected with Kant’s account of sovereignty, since only the sovereign can justifiably coerce others unconditionally. For Kant, the sovereign is she who has the rightful authority to legislate laws and who is subject only to the laws that she gives herself. In the moral realm (or kingdom) of ends, each citizen (...) is both a member of that realm and an equal co-sovereign of its categorically binding laws (GMS, 4:433-34, Reath 2006, p. 5). As such, each citizen is 'subject to the moral law' only insofar as she is 'at the same time lawgiving with respect to it and only for that reason subordinated to it' (GMS, 4:440). But when Kant comes to think about sovereignty in the political sphere, a number of tensions emerge. These tensions emerge because a doctrine of absolutist popular sovereignty, according to which the people are the ultimate holders of sovereignty, seems to be implied by Kant’s underlying normative theory. However, Kant also makes numerous explicit statements which seem to imply a doctrine of absolutist ruler sovereignty, according to which the ruler is the ultimate holder of sovereignty. And this seems inconsistent. However, despite the appearance of inconsistency I shall argue, by exploring the issues of civil disobedience and cosmopolitan peace, that Kant consistently defends an account of absolutist popular sovereignty which is compatible with his core normative commitments. Exploring these issues will also illuminate Kant’s political teleology by showing us the political ends towards which we should work and the means by which we should pursue them. (shrink)

Ziel meines Aufsatzes ist es, die Frage zu stellen, ob die Art und Weise, wie Nietzsche sich auf das Verhältnis zwischen Philosophie und Wissenschaft bezieht, mithilfe des zeitgenössischen methodologischen Naturalismus beschrieben werden kann. Leiter (2009) hat diese Frage mit einem entschiedenen Ja beantwortet, ohne jedoch die Spannungen, die eine solche Antwort mit sich bringen, ausführlich zu diskutieren. Zumindest aus zwei Gründen scheint die Philosophie Nietzsches sich mit der stärkeren Version des methodologischen Naturalismus nicht so leicht in Einklang bringen zu lassen: (...) Erstens aufgrund des Prinzips des Willens zur Macht, das die These impliziert, dass das Intentionalitätsvokabular primitiver bzw. gründlicher als das physikalistische Vokabular sei, als einer Konsequenz aus der Verwendung des pragmatischen Prinzips der Sparsamkeit auf die ontologische Debatte (JGB 36, KSA 5, 54 f.); zweitens aufgrund Nietzsches Auffassung der spezifischen Aufgabe der Philosophie als einer normativen Aufgabe (JGB 211, KSA 5, 144 f.; GM I Anmerkung, KSA 5, 289). Gegen die starke Interpretation Leiters werden hier die folgenden Thesen vertreten: Nietzsche kann nur insofern als ein Vertreter des methodologischen Naturalismus betrachtet werden, als er der Auffassung ist, dass der Philosoph epistemische Tugenden erst dann gewinnt, wenn er sich mit einer wissenschaftlichen Methode vertraut macht (MA I 256, KSA 2, 212). Das bedeutet, dass er sich zumindest vorläufig den Regeln unterwirft, die innerhalb einer bestimmten wissenschaftlichen Gemeinschaft gelten (MA I 635, KSA 2, 360 f.; JGB 188, KSA 5, 108 ff.). Der Philosoph soll dies tun, um die epistemischen Tugenden zu erlangen, die für die normative Aufgabe der Philosophie unentbehrlich sind. Diese epistemischen Tugenden sind wesentlich skeptischer Natur. Sie zu kultivieren, bedeutet sicherlich, epistemische Werte zu fördern, nicht aber unbedingt für sie (AC 54, KSA 6, 236 f.), geschweige denn für ein kausales, bzw. monokausales Erklärungsmodell Exklusivität beanspruchen zu müssen (JGB 21, KSA 5, 35 f.). (shrink)

Serum lmmunglobulin and Complement Levels in the Patients With Head and Neck Carcinoma and the Evaluation of Autoantibody Positivity Ratein this study, smooth muscle antibody (SMA), anti-nücleer antibody (ANA) anti- mitochondrial antibody (AMA), anti-parietal cell antibody (PA), antiglomerular basal membrane antibody (GM), serum immunglobulins and complement-C3 levels have been searched. The positivity rate of ANA (31.91 %) and SMA (38.29 %) were found high in sera of the patients with head and neck carcinoma which had been diagnosed histopathologically. But the (...) positivity rate of AMA (4.25 %) PA (12.76 %) and GM (2.12 %) were low in the same group. ANA and SMA were detected in 1 O of 30 patients with laryngeal carcinoma; ANA were detected in 5 of 9 patients (55.5 %) and SMA were found in 4 of 9 patients (44.5 %) with nasopharyngeal carcinoma. There was no significant deviation in the levels of immunglobulins and complement-C3. The highest levels of immunoglobulins have been detected in patients with laryngeal carcinoma. Finding of high positivity rate of ANA and SMA in the patients with head and neck carcinoma showed an accordance with the other investigators' results. (shrink)

Paul Lodge’s excellent new contribution to the Yale Leibniz series collects together the entirety of the Leibniz-De Volder correspondence, totaling some thirty-three letters, together with a generous selection of relevant excerpts from Leibniz’s concurrent correspondence with Johann Bernoulli, which Lodge has helpfully interspersed throughout. As with previous volumes in the series, the texts appear in the original language, in this case Latin, together with an English translation on opposing pages. Lodge’s transcriptions reflect his careful study of all the available manuscripts (...) and represent a significant improvement over the existing versions in GP II (Leibniz-De Volder) and GM III (Leibniz-Bernoulli). Rounding out the volume are a long introduction (79 pp.), itself a valuable contribution to Leibniz scholarship, together with extensive notes on the texts, a bibliography, and indexes for names and subjects. (shrink)

A tarefa que assumimos nesta dissertação foi colocar a pergunta: como as reflexões de Nietzsche sobre arte puderam, ao menos em parte, terem vindo a ser realizadas por meio de uma fisiologia da estética (cf. GM III 8; CW 7; NW, Objeções)? Antes de pretendermos esgotar o assunto, tentamos compreender a possibilidade de elaboração coerente desse problema ao longo do caminho de pensamento nietzschiano. Mas, para tanto, precisamos lidar com as variações de perspectiva próprias de uma filosofia que não se (...) pretende sistemática e assume suas tensões; e 1886 parece-nos ser um momento chave para vermos essas nuances, em particular no que diz respeito à arte. Naquele ano, Nietzsche escreveu novos prefácios para seus cinco livros publicados até então – O Nascimento da Tragédia (1872), Humano, demasiado humano I (1878) e II (1879-1880), Aurora (1881) e A Gaia Ciência (1882) –, buscando ressaltar o caráter unitário de sua obra, ou, como ele mesmo afirma em uma carta, apresentar a “história de um desenvolvimento”. E justamente a seu livro de estreia, ele adicionou um prefácio intitulado Tentativa de Autocrítica, no qual aponta para os aspectos que o inserem no todo de sua obra, mas, ao mesmo tempo, se distancia das concepções que ali configurariam uma “metafísica de artista”. Essa tensão é tratada no Capítulo I desta dissertação a partir de um contraste entre O Nascimento da Tragédia e a posterior Autocrítica. Após esse primeiro passo, procuramos mostrar no Capítulo II como, já em Humano, Nietzsche apresenta uma reorientação de sua estética, o que em Aurora e A Gaia Ciência se consolida com o enraizamento da moral, da filosofia e das artes na fisiologia, a qual argumentamos poder ser lida como logos da physis. No Capítulo III, indicamos como o ganho do âmbito fisiológico constitui o solo sobre o qual Nietzsche pensa o problema da inferência regressiva que o leva à sua distinção dos valores artísticos entre empobrecimento e abundância (cf. GC 370), que parece orientar sua fisiologia da estética. Por fim, discutimos como o exercício autocrítico nietzschiano e a inferência regressiva convergem em O Caso Wagner na antinomia entre os músicos Wagner e Bizet e na autoencenação nietzschiana como décadent que reconheceu sua doença, seu wagnerismo, e experimentou uma nova saúde. (shrink)