COVID-19 virus caused drastic changes in people's lives, especially in terms of employment. Employees were greatly impacted by this pandemic, as there were terminated from their jobs. This study investigated how depression affects terminated workers and how they manage it throughout the pandemic. -/- A qualitative design was employed to perform this study. A structured type of interview was conducted on five samples using an online platform. To establish the number of samples required for the investigation, convenience sampling was used. (...) The data was analyzed in-depth using a narrative technique, which resulted in the study's findings and conclusions. Five (5) terminated employees such as professional photographer, construction worker, hairdresser, driver, and varsity coach were among the participants. -/- The participants in this study were found to experience depression due to family financial issues caused by the loss of a job during the pandemic. Participants reported feelings of sadness and loneliness, as well as inability to think, low self-esteem, insomnia and hypersomnia, a lack of ambition to accomplish anything, and suicidal or negative thoughts. Accordingly, through their families' emotional support, the participants have been able to overcome their depression. (shrink)

In an effort to inform the discussion surrounding existential risks from AI, we formulate Extinction-level Goodhart’s Law as “Virtually any goal specification, pursued to the extreme, will result in the extinction of humanity”, and we aim to understand which formal models are suitable for investigating this hypothesis. Note that we remain agnostic as to whether Extinction-level Goodhart’s Law holds or not. As our key contribution, we identify a set of conditions that are necessary for a model that aims to be (...) informative for evaluating specific arguments for Extinction-level Goodhart’s Law. Since each of the conditions seems to significantly contribute to the complexity of the resulting model, formally evaluating the hypothesis might be exceedingly difficult. This raises the possibility that whether the risk of extinction from artificial intelligence is real or not, the underlying dynamics might be invisible to current scientific methods. (shrink)

The National Center for Biomedical Ontology is a consortium that comprises leading informaticians, biologists, clinicians, and ontologists, funded by the National Institutes of Health (NIH) Roadmap, to develop innovative technology and methods that allow scientists to record, manage, and disseminate biomedical information and knowledge in machine-processable form. The goals of the Center are (1) to help unify the divergent and isolated efforts in ontology development by promoting high quality open-source, standards-based tools to create, manage, and use ontologies, (2) to create (...) new software tools so that scientists can use ontologies to annotate and analyze biomedical data, (3) to provide a national resource for the ongoing evaluation, integration, and evolution of biomedical ontologies and associated tools and theories in the context of driving biomedical projects (DBPs), and (4) to disseminate the tools and resources of the Center and to identify, evaluate, and communicate best practices of ontology development to the biomedical community. Through the research activities within the Center, collaborations with the DBPs, and interactions with the biomedical community, our goal is to help scientists to work more effectively in the e-science paradigm, enhancing experiment design, experiment execution, data analysis, information synthesis, hypothesis generation and testing, and understand human disease. (shrink)

El Foro Global de Bioética en Investigación (GFBR por sus siglas en inglés) se reunió el 3 y 4 de noviembre en Buenos Aires, Argentina, con el objetivo de discutir la ética de la investigación con mujeres embarazadas. El GFBR es una plataforma mundial que congrega a actores clave con el objetivo de promover la investigación realizada de manera ética, fortalecer la ética de la investigación en salud, particularmente en países de ingresos bajos y medios, y promover colaboración entre países (...) del norte y del sur.a Los participantes en el GFBR provenientes de Latinoamérica incluyeron a eticistas, investigadores, miembros de comités de ética y representantes de autoridades sanitarias provenientes de Argentina, Brasil, Chile, Colombia, Ecuador, El Salvador, Guatemala, Honduras, Panamá, Perú, Nicaragua y la República Dominicana. Una legítima preocupación por la protección de las mujeres embarazadas y sus embriones o fetos ha llevado a la mayoría de los países de la Región de las Américas a limitar la realización de estudios con mujeres embarazadas exclusivamente a aquellos estudios específicos sobre el embarazo, y a requerir la exclusión sistemática de las mujeres embarazadas o de las mujeres que quedan embarazadas en el curso del estudio. Ciertamente, a lo largo de la historia de la ética de la investigación, se ha creído erróneamente que proteger a una población es sinónimo de excluirla de los estudios. Se sabe ahora que proceder así implica exponer a riesgos mucho mayores a la población que se busca proteger. El embarazo implica cambios fisiológicos sustantivos e impacta profundamente la manera como el cuerpo metaboliza los medicamentos. Sin embargo, por evitar hacer investigación con mujeres embarazadas, no se ha producido la evidencia científica necesaria para tomar decisiones sobre tratamientos e intervenciones preventivas con dosis eficaces y seguras para ellas y sus embriones o fetos. A manera de ilustración, en el 2001 había en los Estados Unidos apenas más de una docena de medicamentos aprobados para uso en el embarazo (1) y en el 2011 la Food and Drug Administration (FDA) aprobó por primera vez en 15 años un medicamento para su uso en el embarazo (2). Como consecuencia de no haber producido la evidencia necesaria, se pone en riesgo la salud de las mujeres embarazadas cada vez que se les da atención médica. Las mujeres embarazadas se enferman y las mujeres enfermas se embarazan, y no se sabe si los medicamentos que se les da son eficaces o siquiera seguros para ellas y sus embriones o fetos. (shrink)

This is part 1 of 6 of the dossier What Do We Talk about when We Talk about Queer Death?, edited by M. Petricola. The contributions collected in this article sit at the crossroads between thanatology and queer theory and tackle questions such as: how can we define queer death studies as a research field? How can queer death studies problematize and rethink the life-death binary? Which notions and hermeneutic tools could be borrowed from other disciplines in order to better (...) define queer death studies? The present article includes the following contributions: – MacCormack P., What does queer death studies mean?; – Radomska M., On queering death studies; – Lykke N., Death as vibrancy; – Hillerup Hansen I., What concreteness will do to resolve the uncertain; – Olson P., Queer objectivity as a response to denials of death; – Manganas N., The queer lack of a chthonic instinct. (shrink)

Esta tesis estudia el pensamiento del conservador español Juan Donoso Cortés (1809- 1853). Más precisamente, se ocupa de responder cómo resuelve el problema de la decadencia de la autoridad monárquica en Europa a partir de las revoluciones de 1848. Para abordar este objetivo general elaboramos dos objetivos específicos. El primero busca señalar las continuidades y discontinuidades de la obra donosiana, escindida generalmente en dos períodos: el juvenil, con un Donoso Cortés liberal, y el maduro, que luego de una “conversión religiosa” (...) se vuelca hacia el catolicismo reaccionario. El segundo objetivo hace foco en el concepto de dictadura, bajo la sospecha de que en esta noción reside la clave de su proyecto conservador. Con esto en mente construimos dos hipótesis. La primera afirma que nuestro autor es consciente de la imposibilidad de restituir el proyecto monárquico. La segunda, sugiere la presencia de una fórmula parcialmente decisionista como alternativa a dicho proyecto. Luego de un trabajo de lectura de primera mano de los textos donosianos, las conclusiones confirman las hipótesis y observan que existe una continuidad estructural en las ideas del español, pero también que hay discontinuidades, de las cuales la más importante es su particular noción de dictadura, que denominamos dictadura catolizante. (shrink)

I discuss the roles of journalism in aspirational democracies, and argue that they generate set of pressures on attention that apply to people by virtue of the type of society they live in. These pressures, I argue, generate a problem of democratic attention: for journalism to play its roles in democracy, the attentional demands must be met, but there are numerous obstacles to meeting them. I propose a principle of salience to guide the selection and framing of news stories that (...) I argue may help address the puzzle: the public-as-protagonist principle. -/- . (shrink)

La finalidad del presente ensayo consiste en partir de las nociones interrelacionadas de "capitalismo mundial integrado" (Guattari) y de "sociedad de control" (Deleuze) para intentar una deriva que cruce géneros, épocas y nombres propios: de la filosofía al cine y a la poesía (caminos de ida y vuelta), de Benjamin a Serres pasando por Homero, Kavafis, Cioran o Godard, del tardío imperio romano y sus incertidumbres a la imprecisión de nuestro propio tiempo. Posiblemente, pensar hoy la identidad humana sea como (...) nunca antes un asunto de mezcla, de viaje a través de territorios viejos que demandan una nueva cartografía. -/- The purpose of this essay is to depart from the interrelated notions of "whole global capitalism" (Guattari) and the "control society" (Deleuze) to attempt a drift across genders, epochs and proper names: from philosophy to cinema and poetry (roundtrip roads), from Benjamin to Serres, passing through Homer, Kavafis, Cioran or Godard, from the late Roman empire and its uncertainties to our own time. Possibly, thinking today about human identity is as never before, a matter of mixture, of travel through old territories that demand new maps. (shrink)

No Tratado da natureza humana, David Hume dedica uma longa seção à problemática sobre a possibilidade da existência do mundo externo intitulada “Do ceticismo quanto aos sentidos”. A seção traz idas e vindas do autor no que diz respeito à resposta para o problema. Inicialmente, Hume dá como certa a existência externa dos corpos, i.e., independente das percepções, e avisa que sua investigação se limitará, apenas, às causas que levam a crer nisso. Sua pretensão inicial não é cumprida e logo (...) dá espaço a uma rede de complexos argumentos céticos, os quais colocam em dúvida as realidades independentes das percepções. No último parágrafo, porém, Hume parece retroceder em sua posição e parece tomar como certa a existência independente dos corpos, mais uma vez, tal como fez no começo da seção. O objetivo desse trabalho foi, pois, evidenciar que há dois pontos bem diferentes que caracterizam sua argumentação sobre esse assunto: I) A existência do mundo externo; II) a possibilidade de conhecê-lo. Ao primeiro, a resposta de Hume será positiva, ao segundo ponto, negativa. O ceticismo, portanto, sempre decorreria de qualquer tentativa em conhecer tais realidades independentes, pois, através da argumentação filosófica, da razão, sempre se esbarraria na impossibilidade de sua existência. Ao mesmo tempo, sua realidade ontológica parece se impor pela própria natureza e, com isso, desativa os argumentos céticos, os quais sempre demonstram a impossibilidade de conhecê-lo, i.e., acessá-lo pela razão. Assim, o que se tem sobre o mundo externo são, apenas, impressões geradas através da experiência para com o mesmo. Em vista dos fins supracitados, foram utilizados, além do Tratado, a Investigação sobre o entendimento humano e outros textos do filósofo escocês. (shrink)