This article will contrast two portrayals of Protagoras: one in the "Theaetetus," where Socrates discusses Protagorean theory and even comes to his defense by imitating the deceased sophist; and another in the "Protagoras," where Socrates recounts his encounter with the sophist. I suggest that Plato wants listeners and readers of the dialogues to hear the dissonance between the two portraits and to wonder why Socrates so distorts Protagoras in the "Theaetetus." Protagoras in the "Protagoras" behaves and speaks in ways that (...) are incompatible with the Protagorean position presented in the "Theaetetus.". (shrink)

In this paper, drawing on evidence internal to the Platonic dialogues (supplemented with some ancient testimonia), I answer the question, “How did Plato teach in the Academy?” My reconstruction of Plato’s pedagogy in the Academy is that there was a single person who read the dialogue aloud like a rhapsode (this is in contrast to the dramatic theatrical hypothesis, in which several speakers function as actors in the performance of a dialogue). After the rhapsodic reading, students were allowed to ask (...) that portions of the text to be re-read, to ask a question about the text, and were encouraged to enter into a broader conversation about the topic and themes brought out by the text. This later pedagogical method of interrogating and investigating a dialogue is of more importance than the mere reading of a dialogue. I contend that Plato’s experiences teaching were woven into some of the dialogues, and that Plato’s pedagogy reflects some of the ways that he taught in the Academy. I propose that excellent points made by students may have been written into revised forms of the dialogue. And not only good points, but also mistakes in reasoning may have been added into the dialogues. I suggest that the way certain dialogues are organized with “guest lecturers” and “tag-team” philosophical debates reflect Plato’s pedagogy in the Academy. Plato’s broadmindedness, his openness to various and opposing viewpoints, is also evident from both outside and inside of the dialogue. Lastly, drawing on the idea of Socratic mimēsis, I give a plausible curriculum for how Plato may have used the dialogues to teach them: he had his students “play” with them. Plato may have asked his students to enter into the roles of the characters in the dialogues to better understand them and the type of person they represent. Plato may have also asked students to take over from the position of the character in the dialogue and to suggest a better, truer account of things than what the characters said or did. (shrink)

In the "Republic," Plato has Socrates attack poetry’s use of mimēsis, often translated as ‘imitation’ or ‘representation.’ Various scholars (e.g. Blondell 2002; Frank 2018; Halliwell 2009; K. Morgan 2004) have noticed the tension between Socrates’ theory critical of mimēsis and Plato’s literary practice of speaking through various characters in his dialogues. However, none of these scholars have addressed that it is not only Plato the writer who uses mimēsis but also his own character, Socrates. At crucial moments in several dialogues, (...) Socrates takes on a role and speaks as someone else. I call these moments “Socratic mimēsis.” While previous commentators have noticed some of these moments, they have either overstated their rarity or they have not studied them collectively. My dissertation is the first in-depth investigation of this phenomenon in the dialogues. Socrates’ dramatic imitation of others is way of teaching in a voice separate from his own, and it is also a way for Plato to speak to, and to educate, different kinds of audiences. Although “Socratic mimēsis” occurs throughout the Platonic corpus, I focus on three passages from three different dialogues, which are paradigm instances: [1] in the "Crito" Socrates plays the part of ‘the Laws’ (50a-54c); [2] in the "Theaetetus" he acts the part of ‘Protagoras’ (166a-168c); and [3] in the "Menexenus" he recites a funeral speech learned from ‘Aspasia’ (236d-249c). Instead of one-sidedly reading the dialogues as either only literary works of art or as only a series of philosophical arguments, this study gleans philosophic insights from the literary and dramatic details of the dialogues. In chapter one I argue that in the "Crito" Socrates tries to convince Crito of a universal and absolute ethics based on never committing injustice, but Crito is not able to understand. In order to make Crito more just—but not yet at the level of Socratic ethics—Socrates creates ‘the Laws’ to persuade Crito to expand his personal notion of justice. Socrates instills a political obedience in place of Crito’s existing lawlessness as a second-best recourse. Plato expects the astute listener or reader to see the contrast between Socrates’ earlier ethical principles, said in his own voice, with what he says in the voice of ‘the Laws.’ In chapter two I argue that in the part of the "Theaetetus" where Socrates defends Protagoras (often called ‘the Defense’), Socrates, by imitating ‘Protagoras,’ is actually criticizing Protagorean relativism. The Protagorean theory cannot account for mimēsis and Socrates’ mimetic act performatively contradicts the identity of appearance and reality, which the theory presupposes. Finally, in chapter three I argue that in the Menexenus the funeral oration that Socrates recounts for Menexenus that he heard from ‘Aspasia’ is actually a disguised criticism of political rhetoric and of Athenian imperialism. Although the speech is never interrogated within the dialogue, Plato provokes the listener or reader outside the dialogue to question its message and to see how it conflicts with many of Socrates’ positions in other dialogues. Beyond reconsidering the long-standing and persistent view that Plato was against poetry and mimetic performance, I re-examine the role that performance and role-playing can have in philosophy and pedagogy more generally. Actors, by taking on other personas, and audience members, in observing actors and their actions, are both involved in acts of imagination that can expand their horizon of thinking and feeling. (shrink)

This is a short entry on "Metatheatre" in Section 4, "Concepts, Themes and Topics Treated in the Dialogues," in The Bloomsbury Handbook of Plato, edited by Gerald Press and Mateo Duque.

This is a short entry on "Comedy" in Section 3, "Important Features of the Dialogues," in The Bloomsbury Handbook of Plato, edited by Gerald Press and Mateo Duque.

At the end of the first hypothesis, Parmenides gets Aristotle to agree that being [οὐσίας] must be in time; that is, that being must partake in at least one of the temporal modes: either to have been in the past, to be in the present, or it will be in the future (140e-142a). If this is true, then “the one does not partake in being” (141e7-8), meaning temporal being—to which Aristotle agrees, saying “Apparently not” (141e9). Parmenides then gets Aristotle to (...) agree that “Therefore, ‘the one’ in no way is” (141e9-10). This, however, contradicts the very first premise that begins Parmenides’ entire gymnastic exercise, “if one is” (137c4). The problem with the previous conclusion—that to be is to be in time—is that in professing his assent to it, Aristotle, in fact, gainsays it. He performatively contradicts the very thing he wants to assert. Aristotle answers Parmenides question, “Therefore could something partake of being in any way other than in one of those ways?” (141e7-8) with a two-word answer in Greek: “οὐκ ἔστιν [It’s not possible].” We can, therefore, ask of the very claim Aristotle is making—that it is impossible for something to be and not be in time—when in time does it hold true? At what time is it “not possible [οὐκ ἔστιν]” for something to not partake of temporal being? Is it not possible only in the present moment, in the past, or in the future? If Aristotle’s assertion is to have any force it must hold always. It has the same tenselessness as mathematical propositions, like ‘1+1=2.’ Forms, like mathematical entities, must necessarily have atemporal existence. Accordingly, in atemporally maintaining that anything that is must be in time, Aristotle undermines his own assertion. He performatively contradicts the very thing that he wants to affirm. (shrink)

The role of probability is one of the most contested issues in the interpretation of contemporary physics. In this paper, I’ll be reevaluating some widely held assumptions about where and how probabilities arise. Larry Sklar voices the conventional wisdom about probability in classical physics in a piece in the Stanford Online Encyclopedia of Philosophy, when he writes that “Statistical mechanics was the first foundational physical theory in which probabilistic concepts and probabilistic explanation played a fundamental role.” And the conventional wisdom (...) about quantum probabilities is that they are basic, not reducible to the types of probabilities we see in statistical mechanics. In the first section of this paper, I’ll argue that in fact classical physics was steeped in probability long before statistical mechanics came on the scene, specifically, that an objective measure over phase space is an indispensable component of any informative physical theory. In the next section, I’ll argue that this objective measure is the fundamental form of physical probability and that quantum probabilities can be defined in terms of it. In the last, I’ll raise some questions about the metaphysical status of the fundamental measure. (shrink)

In this essay, I propose a reading of two contrasting passions, two kinds of erōs, in the "Symposium." On the one hand, there is the imperialistic desire for conquering and possessing that Alcibiades represents; and on the other hand, there is the productive love of immortal wisdom that Diotima represents. It’s not just what Alcibiades says in the Symposium, but also what he symbolizes. Alcibiades gives a speech in honor of Socrates and of his unrequited love for him, but even (...) here Alcibiades recounts his attempted seduction of Socrates as a failed conquest, as an unsuccessful attempt to violently take possession of something that Socrates has within him. Even more importantly, in 416 BCE (the dramatic date of Agathon’s symposium) Alcibiades was soon to encourage his fellow countrymen to set off on the ruinous Sicilian expedition. Alcibiades’s actions behind-the-scenes of the "Symposium" reveal the clearest manifestation of his imperialistic erōs (for political power in Athens). They also constitute some necessary background to the dialogue, which Plato’s Athenian readers would have had in mind. Where else can we catch a glimpse of this disastrous desire? It is best illustrated in Thucydides’s "History." I show that the beginnings of this political passion can already be seen in Pericles’s funeral oration (2.35-46, specifically 2.43.1) and that after Pericles’s death, Alcibiades stokes this erōs to such a fevered pitch that the Athenians agree to launch the tragic venture against Sicily. Opposed to this political passion, is Diotima’s. She tries to reorient this misguided erōs and presents an alternative form of desire for everlasting wisdom (philosophia). (shrink)

In this paper, I defend an empiricist account of modality that keeps a substantive account of modal commitment, but throws out the metaphysics. I suggest that if we pair a deflationary attitude toward representation with a substantive account of how scientific models are constructed and put to use, the result is an account that deflates the metaphysics of modal commitment without deflating the content of modal claims.

The logos question, one of the most important among the subjects that traverse the Plato's Sophist, has in fact some different aspects: the criticism of father Parmenides' logos, that is unable to speak about the not-being, but also about the being; the relations between logos and its cognates, phantasia, doxa and dianoia; the logos’ complex structure, that is a compound with onoma and rema; the difference between naming and saying, two distinct but inseparable actions; the logical and ontological conditions that (...) make possible to say the truth, or to lie or simply to joke; the necessity of a most flexible logos that allows us to speak about the not-being, and about the being, but at the same time is a logos dangerously similar to the sophist’ one; finally, the identity between the power to produce “spoken images” and the very power to speak. The aim of the present article is giving a systematical view of the matter that grasps all these faces. (shrink)

The radical evil. Notes on the revolt of masses. In his Religion within the Limits of Reason Alone, Kant speaks about a radical evil present in the human being, a tendency to place before the desire with regard to the rational duty, which is impossible to tear up by the roots from the human nature. In The revolt of the masses, Ortega also speaks about an evil that is anyway present in the so called mass-man, in each one of us, (...) and that is not to eradicate. The aim of this paper is to read the book of Ortega y Gasset in dialogue with Kant. (shrink)

The temporality of human action is very peculiar: different from the cosmic time and even paradoxical, inasmuch as it is really a circular time. The aim of this essay is to study this circularity in the sphere of human activity through the relations between the notions of potency and habit in the Aristotelian Ethics, among others structural conditions of the action. These structural conditions are explored by Aristotle as those which make possible to judge the actions.

Los más diversos teóricos de la modernidad suelen presentar este período como un proceso continuo de desarrollo tecnológico y económico, progreso en las artes y las ciencias, expansión de la democracia y racionalización de las instituciones y las costumbres. Sin embargo, persisten las contradicciones del capitalismo, el colapso de la civilización es inminente y el Pueblo no vive ni ha vivido en la modernidad tal y como sus teóricos la describen. Esto es tanto más cierto en nuestro país, habitado por (...) una suerte de magdaleniense o pre-Tartessos lleno de cacharritos con iconos, llamadas, avisos, avatares, tamagotchies, móviles y juegos online integrados sin la menor discrepancia sobre una capa de rituales del año de la polka, fetiches, incienso, lágrimas, sangre, joyas, ofrendas, sacrificios, reliquias de miembros de santos y matriarcas fenicio-neolíticas devenidas madres de Cristo al tiempo que supporters del equipo de fútbol local. El ultrarracionalismo se presenta como un nuevo método y movimiento filosófico cuya voluntad es afrontar los desafíos del futuro sin dejar de hacer justicia a esta auténtica marejada de lo grotesco. (shrink)

This article is a commentary of the section 5.552 of the Tractatus, about the “experience” that is necessary to understand logic, from the point of view of the so called continental philosophy. In this commentary are tackled some questions: what is exactly this “experience”?; what does mean that logic is a speculative image of the world?; how are the relations between logic and metaphysics (the two components of philosophy, according to Wittgenstein)? All these questions lead us to the conception of (...) philosophy present in the Tractatus and to the role, so important, the two following problems play in this book: the reflection on the philosophical method and the transcendental character of being. Just for this it is necessary to take it seriously the opposition between speaking of something and speaking about something, employed in the final section and so clear in German as habitually mistranslated. (shrink)

The necessity of a continuous creation by God, the need of a creation that is prolonged in the time, is an important issue in the Metaphysics of Descartes; for the being of the human conscience is not so persistent and so strong as the being of a really substance. The Cartesian cogito raises the problem of the weakness of this needy being: the distance between what is in each case thought, which is not temporal, and the thinking itself, which is (...) in the time. Descartes has very interesting observations about this theme. (shrink)

This essential reference text on the life, thought and writings of Plato uses over 160 short, accessible articles to cover a complete range of topics for both the first-time student and seasoned scholar of Plato and ancient philosophy. It is organized into five parts illuminating Plato’s life, the whole of the Dialogues attributed to him, the Dialogues’ literary features, the concepts and themes explored within them and Plato’s reception via his influence on subsequent philosophers and the various interpretations of his (...) work. This fully updated 2nd edition includes 19 newly commissioned entries on topics ranging across comedy, tragedy, Xenophon, metatheatre, gender, musical theory, animals, Orphism, political theory, religion, time, Hellenistic philosophy and post-Platonic ancient commentaries. It also features revisions to the majority of articles from the 1st edition, including 8 which have been completely re-written, and 12 which have had the references substantially revised. Reflecting the growing diversity of Plato scholarship across the world, this edition includes contributions from a wide range of scholars who enrich the field and provide students and scholars with a vital resource for study and reference. (shrink)

The abrupt shift in learning mode demands students to adjust from the comfort of their homes, as well as the challenges of face-to-face learning. As a result, as the pandemic fades, institutions in the Philippines have begun to reopen their doors to students. Hence, this study employed a correlational design to investigate the relationship between procrastination and academic burnout among 150 first-year college students in a state university. Based on the statistical analysis, the r coefficient of 0.67 indicates a moderate (...) positive correlation between the variables. The p-value of 0.00, which is less than 0.05, leads to the decision to reject the null hypothesis. Hence, a significant relationship exists between procrastination and academic burnout among first-year college students. Implications and recommendations were discussed in the study. (shrink)

The Dominican Pedro de Ledesma was educated at the University of Salamanca, where he became a professor. He is considered one of the last members of the famous School of Salamanca. This work studies his contribution to economic thought as regards tax doctrine. In Ledesma’s thought almost a century of moral reflections developed by the Salamanca professors (such as Vitoria, Azpilcueta, Soto…) crystallises, who were echoed by other Spanish authors. Ledesma recapitulates this reflection by providing his personal (...) point of view on the subject in a historical period in which the Spanish influence had reached global dimensions. (shrink)

Pedro de Ledesma is one of the Dominican theologians of the School of Salamanca involved in the De Auxiliis controversy, i.e., the disputes around a famous book by Luis de Molina on the relation between divine foreknowledge and providence and our free will. Studying an unpublished manuscript by Ledesma and his 1611 book on this subject, the article shows that he opposed Molina with a Thomistic position that we call deflationary. According to this interpretation, God, in moving the (...) created will to do good actions, does not bring about an entity distinct from volition itself. Contrary to other Thomists, he does not think that the immediate effect of the divine motion of the will is an intermediary entity used by God to produce, with the will, the created free act. Ledesma defends his thesis by using some elements of Aristotelian-Thomistic metaphysics, in particular, a minimalist interpretation of the relation between action and passion already present in Domingo de Soto and the specific causality of immanent acts. (shrink)

Throughout the history of Thomism, interpretations of the ontology of God’s physical premotion of human free will have been divided mainly into two main groups. Most authors have thought that physical premotion constitutes a certain “entity” infused by God in the creature, although not all of them accept the account of Cabrera, who affirmed that premotion was a “quality”. On the other hand, there are some authors who understand premotion as a direct intervention of God in the vital act of (...) the creature which does not originates any entity prior to the created deliberate action itself. Báñez himself never spoke of any such entity, although some of his disciples soon adopted this view. One of his disciples, Pedro de Ledesma, is the author who best developed this minimalist approach in his treatise published on the occasion of the Controversy De auxiliis. This paper studies the main reasons used by Ledesma in his book to defend such an interpretation. (shrink)

This is a joint review of Jenann Ismael's 'How physics makes us free' (OUP).

Fisikak duen munduaren ulerkera eta askatasuna (edo nork bere burua gobernatzeko gaitasuna) uztartu daitezkeela defendatu nahi du Ismaelek liburuan. Askatasuna ez dago modan, ordea. Fatalismoa da nagusi. Alde handia dago bizi dugun munduaren eta fisikak deskribatzen duenaren artean, eta ohikoa da “Bizi duguna fisikak ilusioa dela erakusten du” eta horrelakoak entzutea. Beste askori, askatasunaren defentsa metafisikoa lekuz kanpokoa irudituko zaio. Horiek, askatasuna orain eta hemen behar dela defendatuko dute. Ez duela inongo zentzurik askatasuna termino horietan pentsatzeak.

Ismael traces our sense that the past is fixed and the future open to what she calls ‘the practical arrow’ – ‘the sense that we can affect the future but not the past.’ In this piece I draw a sharper distinction than Ismael herself does between agents and mere observers, even self-referential observers; and I use it to argue that Ismael’s explanation of the practical arrow is incomplete. To explain our inability to affect the past we need (...) to appeal to our own temporal orientation as agents, and not merely to the ingredients from physics that allow us to predict the consequences of our actions. [This piece is a commentary on J Ismael’s ‘The Open Universe: Totality, Self-Reference and Time’, to appear in the Australasian Philosophical Review.]. (shrink)

Benet Pererio (1535-1610) began teaching philosophy at the Collegio Romano in 1559. A few years later, the rector, Diego Ledesma, and another professor of the Collegio, Achille Gagliardi, accused him of endorsing Averroistic positions during his lectures. This episode has recently been studied, among others, by Paul Richard Blum, who has blurred the lines of the alleged Averroism of Pererius, identifying a series of sources, often Neo-Platonic, which suggest an exploitation of the allegation of Averroism by Ledesma. In (...) turn, Christoph Sander argued that the point of quarrel was not so much about the content as about the way of teaching philosophy by Pererio. In my article, on the other hand, the ‘Pererio case’ is re-considered in the light of some manuscript sources which show how in Pereiro’s intellectual path the positions of the major philosophical authorities, starting with Aristotle, could not withstand the test of rational investigation: Theophrastus, Themistius, Simplicius and Averroes, up to Albert the Great and Thomas Aquinas. Pereiro, accordingly, found himself freed from ‘sacred authorities’, and, if exalting Averroes, he did so only as a commentator, but without adhering to his doctrines. (shrink)

In 1513, the Fifth Council of the Lateran significantly impacted on early-modern Christian philosophy. As is well known, the papal bull Apostolici regiminis condemned certain philosophical doctrines contradicting the personal immortality of the soul. Moreover,the bull prohibited to defend the notion of a double truth in philosophical disputations and urged universities to meet the prescriptions of this decree. This article will shed light on how thispapal intervention in the practice of schooling was met at the early Jesuit college in Rome (...) and the role of Diego de Ledesma, the college’s educational designer, in implementing the bull’s concerns. (shrink)

Ismael aims for an understanding of the nature of an embedded perspective of agents in a world. If successful, this would explain a cluster of ways in which from an embedded perspective, we experience the world in an array of temporally asymmetric ways. Moreover, these are ways that have led many philosophers to rather metaphysically inflationary views about the nature of time, according to which time itself really is dynamical, and is characterized by the movement of an objectively (i.e., (...) non-perspectival) present. Ismael aims to explain these features of our experience without positing any such metaphysical picture. She argues that there are constraints which prevent us from taking this Olympian conception of the world and our place in it, and that these, jointly, explain why we experience the world in these temporally asymmetric ways. We take up two related questions. First, what it would mean to say that these constraints are not merely epistemic, and second, how far these constraints get us in explaining why we experience the world in these ways. (shrink)

Matteo Ricci (1552-1610) was an Italian Jesuit and one of the first Christian missionaries to China in the modern era. He was a genuine polymath—a translator, cartographer, mathematician, astronomer, and musician. Above all, Ricci was a missionary for the gospel. As we briefly examine his 1603 seminal work, The True Meaning of the Lord of Heaven, our hope is that we, as evangelical educators, will perceive some of the deeper principles necessary for our own missionary work among unreached people.

I introduce the seven papers in this special issue, by Andy Clark, Je´roˆme Dokic, Richard Menary, Jenann Ismael, Sue Campbell, Doris McIlwain, and Mark Rowlands. This paper explains the motivation for an alliance between the sciences of memory and the extended mind hypothesis. It examines in turn the role of worldly, social, and internalized forms of scaffolding to memory and cognition, and also highlights themes relating to affect, agency, and individual differences.

Gruber et al. (2022) and Buonomano and Rovelli (Forthcoming) aim to render Q18 consistent the picture of time delivered to us by physics, with the way time seems to us in experience. Their general approach is similar; they take the picture of our world given to us in physics, a picture on which there is no global “moving” present and hence no robust temporal flow, and attempt to explain why things nevertheless seem to us as they do, given that our (...) world is that way. In this, they follow in the footsteps of Hartle (2005), Callender (2017), and Ismael (2017), who argue that any information gathering system (an IGUS) will, in learning to navigate our world, represent the distinctions between past, present, and future, and represent their own changing trajectory through spacetime. While we are generally very sympathetic to this approach, there are several places where we disagree. (shrink)

RELAÇÃO E EFEITOS BIOQUÍMICO-NUTRICIONAIS SOBRE AS ALTERAÇÕES DO CORPO LÚTEO EM VACAS -/- Emanuel Isaque Cordeiro da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim [email protected] ou [email protected] WhatsApp: (82)98143-8399 -/- •__7. ALTERAÇÕES DO CORPO LÚTEO -/- A estrutura funcional desenvolve-se a partir da cavidade folicular após a ovulação. O corpo lúteo é constituído pelas células da teca interna (pequenas e ativas na primeira fase do seu desenvolvimento) e células da granulosa (grandes e ativas na segunda metade do seu (...) desenvolvimento). As principais características de cada tipo de célula podem resumir-se da seguinte forma: As células pequenas são mais sensíveis à ação da LH porque possui uma quantidade maior de receptores biologicamente ativos para esta hormona e a resposta é mediada pelo sistema AMPc-adelinato ciclase. As grandes células lúteas têm menos receptores para a LH (a maior quantidade são para a PGF2α e a PGE2), e são as responsáveis pela produção da oxitocina luteal (BAH, et al. 2006; CAMPO, 2003). Contrariamente às pequenas células lúteas, a produção de progesterona (P4) é parcialmente controlada pelo sistema Ca+2 - Fosfatil inositol-quinase C (CAMPO, 2003). A regulação da função do corpo lúteo é um mecanismo complexo. Nela intervêm fatores tróficos e líticos que estão presentes em forma simultânea durante todo o ciclo estral, e portanto a estimulação ou inibição da síntese e secreção de P4 depende do balanço entre estes fatores. (CAMPO, 2003). Dentro dos fatores tróficos, os nutrientes desempenham um papel relevante sobre a luteólise e as funções luteotrópicas, entre estas pode-se citar a ação das seguintes: -/- 7.1 Vitaminas Deficiência em betacarotenos. Vitamina A é um termo genérico que designa qualquer composto com atividade de retinol, o trans-retinol, é o composto base, sua forma aldeído e ácido são chamados de retinol e ácido retinóico, respectivamente. Por outro lado, a forma ativa da Vitamina A participa no mecanismo da visão, como 11-cis-retinal. Adicionalmente, o betacaroteno, considerado uma provitamina A é a única forma em que esta encontra nas plantas. Em sentido nutricional, a família da Vitamina A compreende todos os compostos que possuem atividade de retinol, incluindo cerca de cinquenta carotenoides que possuem atividade de provitamina A, aceitando-se que o mais ativo é o trans-betacaroteno (TORRES, et al. 2002). As vitaminas que são necessárias para o crescimento e a produção, também são essenciais para a reprodução. As recomendações atuais de vitamina A são de 75.000 UI/dia durante a lactação e 80.000 UI/dia (nota: 1 mg de Vitamina A = 400 UI) durante o período seco nas vacas leiteiras. A suplementação com vitamina A tem pouco risco de toxicidade, enquanto a sua deficiência pode retardar o aparecimento do primeiro cio/estro, induzir cios/estros silenciosos, aumentar o número de quistos ováricos, reduzir os índices de concepção, causar abortos, mortes embrionárias e ocasionar o nascimento de bezerros debilitados e fracos, uma vez que não irão nascer com os índices e requerimentos ideais de nutrientes passados da mãe para o feto pela placenta, e que, já que a mãe possui deficiência nutricional, o colostro não terá o efeito completo para passar a imunidade essencial ao neonato. Embora os mecanismos de ação não sejam claros, foram notificadas maiores secreções de esteroides ováricos quando as concentrações de β-carotenos no fluido folicular foram elevadas; logo, foram observadas maiores concentrações elevadas de β- estradiol e vitamina A nos folículos que terminaram em ovulação do que naqueles que terminaram em atresia. Para evitar as perdas reprodutivas por deficiência de vitamina A, pode-se optar pela administração oral ou injetável desta ao animal, mediante dois métodos: o primeiro consiste em adicionar 1 a 2,5 kg de premix vitamínico em 1 tonelada de grãos o que supre de 4 a 6.000 UI o que é desejável; o segundo é a administração via injetável em quantidades vide bula do fármaco. 7.2 Minerais O excesso de fósforo é absorvido principalmente no intestino delgado dos mamíferos através de um mecanismo de transporte ativo dependente do sódio, que é estimulado pela pró-hormona 1,25- hidroxivitamina D3. Os ruminantes são capazes de absorver o fósforo dietético em proporção direta às quantidades presentes na ração. Estima-se que aproximadamente 1% do corpo animal é composto de fósforo, do qual 85% está presente nos dentes e no tecido ósseo. Os tecidos moles são capazes de conter entre 0,15-0,20% de fósforo sob a forma de fosfoproteínas, nucleoproteínas, fosfolipídios, fosfato creatinina, adenosintrifosfato, glicose-6-fosfato, etc. Ao nível do plasma sanguíneo, o fósforo apresenta valores de 12,09 mg/dl. Os valores plasmáticos de fósforo são regulados principalmente pelo rim, sendo observado um aumento na excreção urinária do elemento inorgânico quando este excede a capacidade de transporte (REBOLLAR & MATEOS, 1999). O fósforo faz parte dos fosfolipídios, que são importantes no transporte de lipídios e seu metabolismo, como componente das membranas celulares. O fosfato faz parte do RNA e do DNA, componentes celulares vitais, e são essenciais para a síntese proteica. O fosfato faz parte de sistemas enzimáticos como a cocarboxilase e NAD, portanto está envolvido em todos os processos de síntese e regulação energética, dado que o corpo lúteo requer altas quantidades de energia para a síntese celular e hormonal, um excesso de fósforo pode bloquear a capacidade renal da sua regulação gerando um desequilíbrio catiônico que descompensa a relação Na:K, já que deverão ser excretados íons fosfato para regular o equilíbrio ácido-básico, desta forma, os processos celulares em tecidos de alta sensibilidade como o ovário serão afetados em sua função. A situação para prevenção de problemas relacionados ao fósforo (P) já foi tratada em assuntos anteriores, porém, sempre vale frisar para o leitor fiel que me lê que as exigências de P presentes na matéria seca (MS) variam entre 0,17 e 0,59% de P por kg/MS para bovinos de corte e em 0,32 a 0,44% por kg/MS para o gado leiteiro. Dessa forma, dados obtidos por pesquisas, ditam que para a mantença de uma vaca ou quaisquer outra categoria bovina o ideal é o consumo de 1.43 g/100 kg de peso vivo (PV), garantindo assim a prevenção de possíveis afecções reprodutivas como as alterações do corpo lúteo. Gramíneas, forragens, leguminosas e os concentrados fornecem muito bem os requerimentos de fósforo para os animais, todavia deve-se estar atento as relações e dependências do P com outros elementos como o Ca e a relação Na:K (10-15:1 idealmente). 7.3 Compostos estrogênicos Os fitoestrogênios afetam repetidamente a estabilidade do corpo lúteo. Os compostos estrogênicos encontrados principalmente em leguminosas pertencem principalmente a três grupos: isoflavanos, isoflavonas, presentes no gênero Trifolium e praticamente restritos às leguminosas, e cumestanos, que foram estudados na alfafa (Medicago sativa) e na Melilotus alba. Todas as isoflavonas sofrem algum grau de transformação no rúmen, sendo o Isoflavonoide formononetina, na realidade um pró-estrógeno, o único que se ativa no ecossistema ruminal ao ser convertido em equol, enquanto que as demais são degradadas a produtos inativos (RAMOS, et al. 1998). Por fim, a alta concentração no sangue do equol retarda a retroalimentação sobre a hipófise mediante a qual se reduzem os níveis de FSH para dar lugar à onda ovulatória de LH, se esta não ocorrer, o corpo lúteo obviamente não se formará. O conhecimento acerca dos estrogênios na alimentação animal é defasado nos livros sobre o tema, no entanto, o criador pode ficar tranquilo no que tange o tema na prática da sua fazenda e dos seus animais, uma vez que tal elemento é muito bem fornecido naturalmente por meio dos alimentos volumosos presentes no seu pasto. -/- Apoio -/- Realização -/- REFERÊNCIAS BIBLIOGRÁFICAS BAH, Mamadou M. et al. Role of intraluteal prostaglandin F2α, progesterone and oxytocin in basal and pulsatile progesterone release from developing bovine corpus luteum. Prostaglandins & other lipid mediators, v. 79, n. 3-4, p. 218-229, 2006. BERCHIELLI, Telma Teresinha; PIRES, Alexandre Vaz; OLIVEIRA, SG de. Nutrição de ruminantes. Jaboticabal: funep, 2006. BINDARI, Yugal Raj et al. Effects of nutrition on reproduction-A review. Adv. Appl. Sci. Res, v. 4, n. 1, p. 421-429, 2013. BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. CAMPO, E. Comportamiento reproductivo del ganado Bovino y Bufalino. 2003. Universidad Agraria de la Habana. Havana, 2003. DEHNING, R. Interrelaciones entre nutrición y fertilidad. In: Curso Manejo de la Fertilidad Bovina18-23 May 1987Medellín (Colombia). CICADEP, Bogotá (Colombia) Universidad de La Salle, Medellín (Colombia) Instituto Colombiano Agropecurio, Bogotá (Colombia) Sociedad Alemana de Cooperación Técnica-GTZ (Alemania), 1987. DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. FRAZER, Grant S. Bovine theriogenology. Veterinary Clinics: Food Animal Practice, v. 21, n. 2, p. xiii-xiv, 2005. GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. HURLEY, W. L.; DOANE, R. M. Recent developments in the roles of vitamins and minerals in reproduction. Journal of Dairy Science, v. 72, n. 3, p. 784-804, 1989. KUMAR, Sudhir et al. Importance of micro minerals in reproductive performance of livestock. Veterinary world, v. 4, n. 5, p. 230, 2011. MAAS, John. Relationship between nutrition and reproduction in beef cattle. The Veterinary Clinics of North America. Food Animal Practice, v. 3, n. 3, p. 633-646, 1987. PASA, Camila. Relação reprodução animal e os minerais. Biodiversidade, v. 9, n. 1, 2011. RAMOS, Graciano et al. Los compuestos secundarios de las plantas en la nutrición de los herbívoros. Archivos de Zootecnia. 47: 597-620, 1998. REBOLLAR, Paloma García; MATEOS, Gonzalo González. El fósforo en nutrición animal. Necesidades, valoración de materias primas y mejora de la disponibilidad. CURSO DE ESPECIALIZACIÓN FEDNA. Avances en nutrición y alimentaciín animal, XV, p. 19-64, 1999. SHORT, Robert E.; ADAMS, D. C. Nutritional and hormonal interrelationships in beef cattle reproduction. Canadian Journal of Animal Science, v. 68, n. 1, p. 29-39, 1988. TEIXEIRA, J. C.; TEIXEIRA, LFAC. Alimentação de bovinos leiteiros. FAEPE, Lavras, 1997. TEIXEIRA, J. C. Nutrição de ruminantes. Lavras: FAEPE, 1992. TORRES, M. et al. Aspectos Farmacológicos relevantes de las Vitaminas Antioxidantes (E, A y C). Archivos Venezolanos de Farmacología y Terapéutica, v. 21, n. 1, p. 22-27, 2002. YASOTHAI, R. Importance of minerals on reproduction in dairy cattle. International Journal of Science, Environment and Technology, v. 3, n. 6, p. 2051-2057, 2014. -/- Emanuel Isaque Cordeiro da Silva Belo Jardim, 29 de março de 2020. (shrink)

1000 time-travelers travel back in time, each with the intention of killing their own infant-self. If there is no branching time, then on pain of bringing about a logical contradiction, all must fail. But this seems inexplicable: what is to ensure that the time-travelers are stopped? For a time, this inexplicability objection was thought to provide evidence that there is something incoherent about the possibility of backwards time travel in a universe without branching time. There is now near-consensus, however, that (...) the objection has no bite: there is nothing inexplicable about the mass failure. Lewis, Sider and Ismael independently argue that since it is built into the description of the class of cases considered that the time-travelers must fail – and so we consider only unsuccessful attempts – there is no mystery. Smith argues that the absence of possible worlds at which auto-infanticide is committed suffices as a complete explanation for the failures. And Baron and Colyvan maintain that available causal and logical explanations jointly account for everything that needs accounting for. I argue that these are wrong. There is remaining, problematic inexplicability. For backwards time travel not to lead to logical contradiction, something would need to do logic’s bidding, after all. (shrink)

The Principal Principle (PP) says that, for any proposition A, given any admissible evidence and the proposition that the chance of A is x%, one's conditional credence in A should be x%. Humean Supervenience (HS) claims that, among possible worlds like ours, no two differ without differing in the spacetime-point-by-spacetime-point arrangement of local properties. David Lewis (1986b, 1994a) has argued that PP contradicts HS, and the validity of his argument has been endorsed by Bigelow et al. (1993), Thau (1994), Hall (...) (1994), Strevens (1995), Ismael (1996), Hoefer (1997), and Black (1998). Against this consensus, I argue that PP might not contradict HS: Lewis's argument is invalid, and every attempt – within a broad class of attempts – to amend the argument fails. (shrink)

José Hugo Burel Guerra nació el 23 de marzo de 1951 en Montevideo (Uruguay). Desde 2017 es miembro de número de la Academia Nacional de Letras del Uruguay (ANL), institución a la cual ingresó con su discurso titulado «Ismael». Es licenciado en Letras por el Instituto de Filosofía, Ciencias y Letras (que se conoce en la actualidad como UCUDAL) y la Pontificia Universidad Católica de Río Grande do Sul. Aparte de ser escritor, se ha desempeñado como músico, publicista, diseñador (...) gráfico, profesor y periodista. Dentro del ámbito literario, ha publicado cuentos, novelas y ensayos. Entre su producción, algunos títulos son los siguientes: Esperando a la pianista y otros cuentos (1983), Tampoco la pena dura (1989), Los dados de Dios (1997) El autor de mis días (1999), El guerrero del crepúsculo (2001), Tijeras de plata (2003), Los inmortales (2004), El corredor nocturno (2005), El desfile salvaje (2007), El caso Bonapelch (2014) y La misteriosa muerte de Eleanor Rigby (2019). Asimismo, ha sido merecedor de múltiples distinciones. Algunas de ellas fueron el segundo premio del concurso literario de Radio Carve (1975), el Premio Juan Rulfo de Radio Francia Internacional (1995), el Premio de Inéditos del MEC-Ministerio de Educación y Cultura (1995), el VII Premio Lengua de Trapo de Narrativa (2001), el Premio Bartolomé Hidalgo (2004), el Premio Alas (2008) y el Premio Libro de Oro (2014). (shrink)

Luego de un rápido bosquejo de las etapas por las que ha pasado el pensamiento filosófico-cristiano en América Latina, el trabajo se concentra en la principales tendencias y autores en el período que va de la década del 40 del siglo XX hasta el momento que se publica el ensayo en 1998.

Metaphysics, seen as a legitimizing narrative or a paradigm (Lyotard, 1984), prop up a certain practice in providing the basis for its assumptions. While Western medicine can be properly characterized as governed by a biophysical model (Hewa, 1994; Bates, 2002), such a model for traditional healing practices in the Philippines has yet to be derived. No philosopher has attempted to derive an indigenous metaphysics from traditional healing practices. The only study made so far (Fajardo & Pansacola, 2013), however, needlessly pigeonholes (...) these unique practices into incommensurable Western scientific concepts. While they collated data from healers all over the country, they attempted to use Western scientific concepts such as oxygen, carbon, electro-magnetic force, and others. These concepts dangerously obfuscate indigenous understandings of the human body and reality as a whole since they are directly lifted from a language and practice informed by Western metaphysics. Therefore, there has yet to be an adequate extraction of a locally derived metaphysics that informs and self-legitimizes these medicinal practices. Conscious of recent critiques to homogenizing tendencies in Philippine Studies (Guillermo, 2009) and Filipino philosophy (Pada, 2014; Abulad, 2016), specifically that of Mercado (1972) and Timbreza (2017), I attempt to derive a Filipino metaphysics from the traditional healing practices of two traditional healers in San Mateo, Rizal of the Southern Tagalog Region in Luzon through a particularist anthropological approach in Filipino philosophy. I derive four distinct characteristics of this metaphysics which are distinct from the biophysical presuppositions of Western medicine: (1) a law of conservation based on the concept of “balik,” (2) predestination, (3) an ontological dualism between the visible and the invisible, and (4) the performativity of words as utterances. (shrink)