The volume of clinical research is increasing exponentially—far beyond our ability to process and absorb the results. Given this situation, it may be beneficial to consider reducing the flow at its source. In what follows, I will motivate and critically evaluate the following proposal: researchers should conduct fewer clinical trials. More specifically, I c onsider whether researchers should be permitted to conduct only clinical research of very high quality and, in turn, whether research ethics committees should prohibit all other, lower-quality (...) research, even when it might appear to meet some minimal ethical standard. Following a close analysis of the social-value requirement of ethical clinical research, I argue that this proposal is defensible. The problem identified in this paper has two parts, quantity and quality, and some clarification is needed about the latter because “quality” is a highly contested term in the medical literature. When some scholars advocate for high-quality trials, they mean large-scale, simple, explanatory randomized controlled trials. Others, including myself, have defended a different characterization of high-quality research that tends more toward pragmatic trial design and the use of methods other than RCTs. Pragmatic trials aim to provide evidence that directly supports clinical decision-making in “usual” care settings. Unlike explanatory trials, which aim to abstract away from particular settings and patients, in the hopes of creating ideal conditions for the success of an intervention, pragmatic trials deliberately pursue knowledge of high applicability, through the use of representative subjects, clinically important questions, flexible treatment protocols, patient-oriented outcome measures, and so on. I see applicability as a marker of high-quality research. The context in which research is meant to be applied should be the context in which new interventions are evaluated. (shrink)

Editors' introduction to 3rd thematic issue on philosophy of medicine.

The objective of Working Group 4 of the COST Action NET4Age-Friendly is to examine existing policies, advocacy, and funding opportunities and to build up relations with policy makers and funding organisations. Also, to synthesize and improve existing knowledge and models to develop from effective business and evaluation models, as well as to guarantee quality and education, proper dissemination and ensure the future of the Action. The Working Group further aims to enable capacity building to improve interdisciplinary participation, to promote knowledge (...) exchange and to foster a cross-European interdisciplinary research capacity, to improve cooperation and co-creation with cross-sectors stakeholders and to introduce and educate students SHAFE implementation and sustainability. To enable the achievement of the objectives of Working Group 4, the Leader of the Working Group, the Chair and Vice-Chair, in close cooperation with the Science Communication Coordinator, developed a template to map the current state of SHAFE policies, funding opportunities and networking in the COST member countries of the Action. On invitation, the Working Group lead received contributions from 37 countries, in a total of 85 Action members. The contributions provide an overview of the diversity of SHAFE policies and opportunities in Europe and beyond. These were not edited or revised and are a result of the main areas of expertise and knowledge of the contributors; thus, gaps in areas or content are possible and these shall be further explored in the following works and reports of this WG. But this preliminary mapping is of huge importance to proceed with the WG activities. In the following chapters, an introduction on the need of SHAFE policies is presented, followed by a summary of the main approaches to be pursued for the next period of work. The deliverable finishes with the opportunities of capacity building, networking and funding that will be relevant to undertake within the frame of Working Group 4 and the total COST Action. The total of country contributions is presented in the annex of this deliverable. (shrink)

Art among Iranian and Islamic philosophers has always been associated with moral, so that many philosophers have considered art to be synonymous with virtue. By examining Farabi's opinions, it is possible to extract his special ideas about art and artist. In Farabi's theory of Virtuous Art, the artist is on the second floor of utopia and carries religious truths and reasonable happiness. Also, the theory of Virtuous Art has all the aesthetic features and artistic creativity, and in fact, all artistic (...) values are the presupposition of being an art of Virtuous Art. By reflecting on Suhrawardi’s numerous works and intellectual foundations, we can also see that he also paid special attention to the virtuous art and the supreme aspects of art; although he did not directly theorize about the basics of art, but by examining his theories, we can infer the basics of Ishraghi's Virtuous Art. Moreover, Suhrawardi has written some of his works in allegorical and artistic language, and this is a manifestation of Suhrawardi’s Illuminating Art. Among contemporary thinkers, Seyyed Hossein Nasr and Titus Burckhardt have presented an approach with the title of Sacred Art, considering the sacred foundations of art and Traditionalism. (shrink)

The text addresses conceptions of human selfhood and humankind as developed by two major nineteenth-century German-speaking historians, Johann Gustav Droysen and Jacob Burckhardt. It aims at ascertaining to what extent the historical anthropologies proposed by both authors can be considered to be humanistic. We will attempt to provide an answer to this question while locating and discussing both humanistic and anti-humanistic features in their texts. Humanism is understood here as a perspective that emerged within the framework of the philosophy (...) of the Enlightenment, for example, in Immanuel Kant's ethics and in Friedrich Niethammer's pedagogy. On the one hand, we will define Droysen's and Burckhardt's anthropologies as humanistic, stressing their intellectual connection to the universalistic notions of humankind and human nature developed in the late eighteenth-century. On the other, we will relativize this predicament by exploring their main anti-humanistic traits, i.e. nationalism, with regard to Droysen, and aestheticism, in the case of Burckhardt. (shrink)

Despite his opposition to Schopenhauerian pessimism, Nietzsche repeatedly characterises himself as a pessimist of sorts. Here I attempt to take this assertion seriously and offer an interpretation of in what sense Nietzsche can be called a pessimist. I suggest that Nietzsche’s pessimism has to do not with life in general, but with life in its common form: such life is bad because it is characterised by meaningless suffering, and lacks aesthetic value. Against the Christian tradition, Nietzsche denies that there is (...) a value inherent to life itself, and thinks instead, that value must be achieved, but rarely is. This form of pessimism is rooted in Nietzsche’s engagement with the ancient Greeks, and bears important affinities to the thought of Burckhardt on Greek pessimism. (shrink)

Despite his opposition to Schopenhauerian pessimism, Nietzsche repeatedly characterises himself as a pessimist of sorts. Here I attempt to take this assertion seriously and offer an interpretation of in what sense Nietzsche can be called a pessimist. I suggest that Nietzsche’s pessimism has to do not with life in general, but with life in its common form: such life is bad because it is characterised by meaningless suffering, and lacks aesthetic value. Against the Christian tradition, Nietzsche denies that there is (...) a value inherent to life itself, and thinks instead, that value must be achieved, but rarely is. This form of pessimism is rooted in Nietzsche’s engagement with the ancient Greeks, and bears important affinities to the thought of Burckhardt on Greek pessimism. (shrink)

Mit dem treffenden Ausdruck "Der wunderbare florentinische Geist" bezeichnet Jacob Burckhardt den Geist der Erneuerung in Florenz zur Zeit der italienischen Renaissance - des Rinascimento. Er revolutionierte die unterschiedlichsten kulturellen Bereiche, wie etwa das politische Denken, Wissenschaft, Technik und Kunst. Dieser Geist wirkt bis heute fort. In seiner vielfältigen Gestalt dient er als Ausgangspunkt, um den Hintergrund der europäischen Kultur zu erkunden.

It was Lord Northbourne who gifted to the world the term ‘organic farming’. His 1940 book Look to the Land is a manifesto of organic agriculture. In it he mooted a contest of “organic versus chemical farming” which he foresaw as a clash of world views that may last for generations. Northbourne’s ideas were foundational in launching the worldwide organics movement, and the book was a turning point in his own life. This biography relies on primary sources to draw a (...) picture of Lord Northbourne. He was a very shy man, a talented artist, a capable linguist, a keen sportsman and an Olympic silver medallist, a graduate and lecturer in agriculture of the University of Oxford, a lifelong farmer, he was profoundly spiritual, an accomplished author, and as a wordsmith he could be a compelling advocate for his cause as Look to the Land shows. His interest in biodynamics led him to visit Switzerland in 1939 to invite the leading advocate of the times, Dr Ehrenfried Pfeiffer, to present the first conference on biodynamic farming in Britain, and it was in the following year that Look to the Land appeared. Rather than the mechanics or the practices of organics, Northbourne’s book presents the philosophy, the rationale, and the imperative of organic farming. The ideas of his organics manifesto took on a life of their own and were quickly spread globally, with early uptakes in the USA and Australia. Meanwhile, while maintaining lifelong interests and commitments to agriculture and education, Northbourne became progressively more engaged with spiritual matters, and his subsequent writings reflect his growing interest in metaphysics. He translated books by leading perennialist authors Frithjof Schuon, René Guénon, and Titus Burckhardt. Northbourne led a full life, but it is Look to the Land that is his enduring ideological legacy. This biography examines: firstly, the book, its ideas, history, uptake and impact; secondly, Northbourne’s life before Look to the Land; and thirdly, his life after Look to the Land. (shrink)

Nietzsche’s Ecce homo, Notebooks and Letters: 1888-1889 / Translation by Daniel Fidel Ferrer. ©2023 Daniel Fidel Ferrer. All rights reserved. -/- Ecce homo: How One Becomes What One Is (Ecce homo: Wie man wird, was man ist). -/- Who should read Nietzsche? You can disagree with everything Nietzsche wrote and re-read Nietzsche to sharpen your attack. Philosophy. Not for use without adult supervision (required). Philosophy is a designated area for adults only. Read at your own risk. You have the pleasure (...) of reading and of course disagree with all philosophy. Warning philosophical ideas are present. Reading Nietzsche does not mean you will gain anything, in fact, you might lose your previous ideas. -/- Nietzsche does not call this book an autobiography (he has written many short autobiographical sketches before); but rather, uses the expression “I tell myself my life”. -/- Nietzsche was the past philosopher who wrote about our future, “The time is coming when the struggle for the domination of the earth will be waged - it will be waged in the name of basic philosophical doctrines.” KGWB/NF-1881, 11[273]. The world has seen plenty of wars and death, since 1881. The process of the domination of the earth and world is still on-going. -/- What is Nietzsche’s overall project with Ecce homo? -/- Main Leitmotifs in Ecce homo. -/- Christianity as the denial of the will to life, revaluation of all values (Umwerthung aller Werthe), Amor fati, Dionysus as a god and his philosophy (future project for Nietzsche), overthrowing idols, two worlds (“true world" finally became a fable) against Plato eternal world and forms, eternal recurrence or the eternal return of the same (Nietzsche heaviest thought, also his most abysmal thought “abgründlichsten Gedanken”), opposite and counterpart to type of person decadent (décadent), “I count the overcoming of pity among the noble virtues”, against the concept of God (Christian), overman or superman (Übermensch), Will to Power (Wille zur Macht), great politics, immoralist, morality of the Christian church, and Declaration of war (“Kriegserklärung”). -/- Table of Contents -/- Motto [page 3]. Epigraph [pages 4-6]. -/- Preface to the Translation of Ecce homo [pages 7-16] -/- Major Leitmotifs in Nietzsche [pages 17-24]. -/- Translations from Nietzsche’s German to English include. -/- 1). Ecce homo: How One Becomes What One Is (Ecce homo: Wie man wird, was man ist. [pages 25-113]. -/- 2). This poem was included in the first publications of Ecce homo (1908). Glory and Eternity (Ruhm und Ewigkeit). [pages 114-124]. -/- 3). These are all of Nietzsche’s last notebooks (complete) they are numbered 21, 22, 23, and 24. There are a total of 82 notes. Final notes by Nietzsche from the Nachlass (Nachlaß). Sometime in German called the Notizheft. Nietzsche’s notebooks that include some drafts for Ecce homo and other topics he was thinking during his last writings. Dating from October 1888 until early Janurary 1889. [pages 125-191]. -/- 4). Nietzsche’s Letters Regarding Ecce homo. Nietzsche’s letters starting at the end of October 1888 discussing Ecce homo. These are not always the complete letters but include all of the passages of Nietzsche discussing Ecce homo. Complete translation of the last letter Nietzsche wrote. Dated until BVN-1889. #1256. Letter to Jacob Burckhardt in Basel. Turin, about 6 January 1889. [pages 192-223]. -/- Bibliographies [pages 224-254]. -/- Nietzsche’s Philosophy Final Thoughts [pages 255-259]. -/- Enjoy reading Nietzsche's last book. (shrink)

Traditionalism-as a school established at 20th century by Rene Guenon, Amanda Coomaraswamy and expanding and developing by figures like Seyyed Hossein Nasr, Martin Lings, and Titus Burckhardt…- assumes human as vicegerent of God which has an important role in the universe. In this point of view Egalitarianism isn’t acceptable because human beings are different in respect of sexuality, emotions, talents and races. Differences between races and societies prove the necessity of religious plurality on one hand, and unity of the (...) Reality above the forms prove “Transcendence Unity of Religion” on the other. (shrink)