Switch to: References

Add citations

You must login to add citations.
  1. Defining Life as a Non-Essentialist Natural Kind.Jaime Soler Parra - 2019 - Quaderns de Filosofia 6 (2):27.
    Download  
     
    Export citation  
     
    Bookmark  
  • Synthetic Biology as a Technoscience: The Case of Minimal Genomes and Essential Genes.Massimiliano Simons - 2021 - Studies in History and Philosophy of Science Part A 85:127-136.
    This article examines how minimal genome research mobilizes philosophical concepts such as minimality and essentiality. Following a historical approach the article aims to uncover what function this terminology plays and which problems are raised by them. Specifically, four historical moments are examined, linked to the work of Harold J. Morowitz, Mitsuhiro Itaya, Eugene Koonin and Arcady Mushegian, and J. Craig Venter. What this survey shows is a historical shift away from historical questions about life or descriptive questions about specific organisms (...)
    Download  
     
    Export citation  
     
    Bookmark   3 citations  
  • Metabolism Instead of Machine: Towards an Ontology of Hybrids.Julia Rijssenbeek, Vincent Blok & Zoë Robaey - 2022 - Philosophy and Technology 35 (3):1-23.
    The emerging field of synthetic biology aims to engineer novel biological entities. The envisioned future bio-based economy builds largely on “cell factories”: organisms that have been metabolically engineered to sustainably produce substances for human ends. In this paper, we argue that synthetic biology’s goal of creating efficient production vessels for industrial applications implies a set of ontological assumptions according to which living organisms are machines. Traditionally, a machine is understood as a technological, isolated and controllable production unit consisting of parts. (...)
    Download  
     
    Export citation  
     
    Bookmark  
  • How many ways can you die? Multiple biological deaths as a consequence of the multiple concepts of an organism.Piotr Grzegorz Nowak & Adrian Stencel - 2022 - Theoretical Medicine and Bioethics 43 (2):127-154.
    According to the mainstream position in the bioethical definition of death debate, death is to be equated with the cessation of an organism. Given such a perspective, some bioethicists uphold the position that brain-dead patients are dead, while others claim that they are alive. Regardless of the specific opinion on the status of brain-dead patients, the mere bioethical concept of death, according to many bioethicists, has the merit of being unanimous and univocal, as well as grounded in biology. In the (...)
    Download  
     
    Export citation  
     
    Bookmark  
  • Beyond Categorical Definitions of Life: A Data-Driven Approach to Assessing Lifeness.Christophe Malaterre & Jean-François Chartier - 2019 - Synthese 198 (5):4543-4572.
    The concept of “life” certainly is of some use to distinguish birds and beavers from water and stones. This pragmatic usefulness has led to its construal as a categorical predicate that can sift out living entities from non-living ones depending on their possessing specific properties—reproduction, metabolism, evolvability etc. In this paper, we argue against this binary construal of life. Using text-mining methods across over 30,000 scientific articles, we defend instead a degrees-of-life view and show how these methods can contribute to (...)
    Download  
     
    Export citation  
     
    Bookmark   5 citations  
  • “Minimal Metabolism”: A Key Concept to Investigate the Origins and Nature of Biological Systems.Nino Lauber, Christoph Flamm & Kepa Ruiz-Mirazo - 2021 - Bioessays 43 (10):2100103.
    Download  
     
    Export citation  
     
    Bookmark  
  • What Are Definitions of Life Good For? Transdisciplinary and Other Definitions in Astrobiology.Tarja Knuuttila & Andrea Loettgers - 2017 - Biology and Philosophy 32 (6):1185-1203.
    The attempt to define life has gained new momentum in the wake of novel fields such as synthetic biology, astrobiology, and artificial life. In a series of articles, Cleland, Chyba, and Machery claim that definitions of life seek to provide necessary and sufficient conditions for applying the concept of life—something that such definitions cannot, and should not do. We argue that this criticism is largely unwarranted. Cleland, Chyba, and Machery approach definitions of life as classifying devices, thereby neglecting their other (...)
    Download  
     
    Export citation  
     
    Bookmark   6 citations  
  • Modelling Gene Regulation: (De)Compositional and Template-Based Strategies.Tarja Knuuttila & Vivette García Deister - 2019 - Studies in History and Philosophy of Science Part A 77:101-111.
    Although the interdisciplinary nature of contemporary biological sciences has been addressed by philosophers, historians, and sociologists of science, the different ways in which engineering concepts and methods have been applied in biology have been somewhat neglected. We examine - using the mechanistic philosophy of science as an analytic springboard - the transfer of network methods from engineering to biology through the cases of two biology laboratories operating at the California Institute of Technology. The two laboratories study gene regulatory networks, but (...)
    Download  
     
    Export citation  
     
    Bookmark  
  • Epistemology and Anomaly Detection in Astrobiology.Christopher Kempes & David Kinney - 2022 - Biology and Philosophy 37 (4):1-25.
    We examine the epistemological foundations of a leading technique in the search for evidence of life on exosolar planets. Specifically, we consider the “transit method” for spectroscopic analysis of exoplanet atmospheres, and the practice of treating anomalous chemical compositions of the atmospheres of exosolar planets as indicators of the potential presence of life. We propose a methodology for ranking the anomalousness of atmospheres that uses the mathematical apparatus of support vector machines, and which aims to be agnostic with respect to (...)
    Download  
     
    Export citation  
     
    Bookmark  
  • Natural Selection of Independently Originated Life Clades.Margarida Hermida - 2022 - Philosophy of Science 89 (3):454-470.
    Life on Earth descends from a common ancestor. However, it is likely that there are other instances of life in the universe. If so, each abiogenesis event will have given rise to an independently originated life clade, of which Earth-life is an example. In this paper, I argue that the set of all IOLCs in the universe forms a Darwinian population subject to natural selection, with more widely dispersed IOLCs being less likely to face extinction. As a result, we should (...)
    Download  
     
    Export citation  
     
    Bookmark  
  • What Counts as a Memory? Definitions, Hypotheses, and 'Kinding in Progress'.David Colaço - 2022 - Philosophy of Science 89 (1):89-106.
    This paper accounts for broad definitions of memory, which extend to paradigmatic memory phenomena, like episodic memory in humans, and phenomena in worms and sea snails. These definitions may seem too broad, suggesting that they extend to phenomena that don’t count as memory or illustrate that memory is not a natural kind. However, these responses fail to consider a definition as a hypothesis. As opposed to construing definitions as expressing memory’s properties, a definition as a hypothesis is the basis to (...)
    Download  
     
    Export citation  
     
    Bookmark   2 citations  
  • Interactive Models in Synthetic Biology: Exploring Biological and Cognitive Inter-Identities.Leonardo Bich - 2020 - Frontiers in Psychology 11.
    The aim of this article is to investigate the relevance and implications of synthetic models for the study of the interactive dimension of minimal life and cognition, by taking into consideration how the use of artificial systems may contribute to an understanding of the way in which interactions may affect or even contribute to shape biological identities. To do so, this article analyzes experimental work in synthetic biology on different types of interactions between artificial and natural systems, more specifically: between (...)
    Download  
     
    Export citation  
     
    Bookmark  
  • Hidden Concepts in the History of Origins-of-Life Studies.Carlos Mariscal, Ana Barahona, Nathanael Aubert-Kato, Arsev Umur Aydinoglu, Stuart Bartlett, María Luz Cárdenas, Kuhan Chandru, Carol E. Cleland, Benjamin T. Cocanougher, Nathaniel Comfort, Athel Cornish-Boden, Terrence W. Deacon, Tom Froese, Donato Giovanelli, John Hernlund, Piet Hut, Jun Kimura, Marie-Christine Maurel, Nancy Merino, Alvaro Julian Moreno Bergareche, Mayuko Nakagawa, Juli Pereto, Nathaniel Virgo, Olaf Witkowski & H. James Cleaves Ii - 2019 - Origins of Life and Evolution of Biospheres 1.
    In this review, we describe some of the central philosophical issues facing origins-of-life research and provide a targeted history of the developments that have led to the multidisciplinary field of origins-of-life studies. We outline these issues and developments to guide researchers and students from all fields. With respect to philosophy, we provide brief summaries of debates with respect to (1) definitions (or theories) of life, what life is and how research should be conducted in the absence of an accepted theory (...)
    Download  
     
    Export citation  
     
    Bookmark  
  • Synthetic Modelling of Biological Communication: A Theoretical and Operational Framework for the Investigation of Minimal Life and Cognition.Leonardo Bich & Ramiro Frick - 2018 - Complex Systems 27 (3):267-287.
    This paper analyses conceptual and experimental work in synthetic biology on different types of interactions considered as minimal examples or models of communication. It discusses their pertinence and relevance for the wider understanding of this biological and cognitive phenomenon. It critically analyses their limits and it argues that a conceptual framework is needed. As a possible solution, it provides a theoretical account of communication based on the notion of organisation, and characterised in terms of the functional influence exerted by the (...)
    Download  
     
    Export citation  
     
    Bookmark   2 citations