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Leonardo Bich
University of the Basque Country
  1.  48
    Functional Integration and Individuality in Prokaryotic Collective Organisations.Guglielmo Militello, Leonardo Bich & Alvaro Moreno - 2020 - Acta Biotheoretica.
    Both physiological and evolutionary criteria of biological individuality are underpinned by the idea that an individual is a functionally integrated whole. However, a precise account of functional integration has not been provided so far, and current notions are not developed in the details, especially in the case of composite systems. To address this issue, this paper focuses on the organisational dimension of two representative associations of prokaryotes: biofilms and the endosymbiosis between prokaryotes. Some critical voices have been raised against the (...)
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  2.  83
    Glycemia Regulation: From Feedback Loops to Organizational Closure.Leonardo Bich, Matteo Mossio & Ana M. Soto - 2020 - Frontiers in Physiology 11.
    Endocrinologists apply the idea of feedback loops to explain how hormones regulate certain bodily functions such as glucose metabolism. In particular, feedback loops focus on the maintenance of the plasma concentrations of glucose within a narrow range. Here, we put forward a different, organicist perspective on the endocrine regulation of glycaemia, by relying on the pivotal concept of closure of constraints. From this perspective, biological systems are understood as organized ones, which means that they are constituted of a set of (...)
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  3. Auto-organización y autopoiesis.Arantza Etxeberria & Leonardo Bich - 2017 - In Diccionario Interdisciplinar Austral. Instituto de Filosofía - Universidad Austral.
    El prefijo “auto” en autoorganización y autopoiesis se refiere a la existencia de una identidad o agencialidad implicada en el orden, organización o producción de un sistema que se corresponde con el sistema mismo, en contraste con el diseño o la influencia de carácter externo. La autoorganización (AO) estudia la manera en la que los procesos de un sistema alcanzan de forma espontánea un orden u organización complejo, bien como una estructura o patrón emergente, bien como algún tipo de finalidad (...)
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  4. Is Defining Life Pointless? Operational Definitions at the Frontiers of Biology.Leonardo Bich & Sara Green - 2017 - Synthese:1-28.
    Despite numerous and increasing attempts to define what life is, there is no consensus on necessary and sufficient conditions for life. Accordingly, some scholars have questioned the value of definitions of life and encouraged scientists and philosophers alike to discard the project. As an alternative to this pessimistic conclusion, we argue that critically rethinking the nature and uses of definitions can provide new insights into the epistemic roles of definitions of life for different research practices. This paper examines the possible (...)
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  5. An Organisational Approach to Biological Communication.Ramiro Frick, Leonardo Bich & Alvaro Moreno - 2019 - Acta Biotheoretica (2):103-128.
    This paper aims to provide a philosophical and theoretical account of biological communication grounded in the notion of organisation. The organisational approach characterises living systems as organised in such a way that they are capable to self-produce and self-maintain while in constant interaction with the environment. To apply this theoretical framework to the study of biological communication, we focus on a specific approach, based on the notion of influence, according to which communication takes place when a signal emitted by a (...)
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  6.  79
    Understanding Multicellularity: The Functional Organization of the Intercellular Space.Leonardo Bich, Thomas Pradeu & Jean-Francois Moreau - 2019 - Frontiers in Physiology 10.
    The aim of this paper is to provide a theoretical framework to understand how multicellular systems realize functionally integrated physiological entities by organizing their intercellular space. From a perspective centered on physiology and integration, biological systems are often characterized as organized in such a way that they realize metabolic self-production and self-maintenance. The existence and activity of their components rely on the network they realize and on the continuous management of the exchange of matter and energy with their environment. One (...)
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  7.  29
    Interactive Models in Synthetic Biology: Exploring Biological and Cognitive Inter-Identities.Leonardo Bich - 2020 - Frontiers in Psychology 11.
    The aim of this article is to investigate the relevance and implications of synthetic models for the study of the interactive dimension of minimal life and cognition, by taking into consideration how the use of artificial systems may contribute to an understanding of the way in which interactions may affect or even contribute to shape biological identities. To do so, this article analyzes experimental work in synthetic biology on different types of interactions between artificial and natural systems, more specifically: between (...)
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  8. Systems, Autopoietic.Leonardo Bich & Arantza Etxeberria - 2013 - In Dubitzsky, Wolkenhauer, Cho & Yokota (eds.), Encyclopedia of Systems Biology. New York: Springer. pp. 2110-2113.
    Definition The authors’ definition of the autopoietic system has evolved through the years. One of them states that an autopoietic system is organized (defined as a unity) as a network of processes of production (transformation and destruction) of components that produces the components which: (1) through their interactions and transformations regenerate and realize the network of processes (relations) that produced them; and (2) constitute it (the machine) as a concrete unity in the space in which they exist by specifying the (...)
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  9. Emergent Processes as Generation of Discontinuities.Leonardo Bich & Gianluca Bocchi - 2012 - In Gianfranco Minati, Eliano Pessa & Mario Abram (eds.), Methods, models, simulations and approaches towards a general theory of change. Singapore: World Scientific. pp. 135-146.
    In this article we analyse the problem of emergence in its diachronic dimension. In other words, we intend to deal with the generation of novelties in natural processes. Our approach aims at integrating some insights coming from Whitehead’s Philosophy of the Process with the epistemological framework developed by the “autopoietic” tradition. Our thesis is that the emergence of new entities and rules of interaction (new “fields of relatedness”) requires the development of discontinuous models of change. From this standpoint natural evolution (...)
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  10.  74
    Il concetto di “ milieu intérieur”: ruolo e implicazioni teoriche in un approccio sistemico allo studio del vivente.Leonardo Bich - 2012 - In Eloisa Cianci (ed.), Quaderni del CERCO. Epistemologie in Dialogo? Contesti e costruzioni di conoscenze. Rimini: Guaraldi. pp. 179-210.
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  11. Circularities, Organizations, and Constraints in Biology and Systems Theory.Leonardo Bich - 2016 - Constructivist Foundations 12 (1):14-16.
    Open peer commentary on the article “Circularity and the Micro-Macro-Difference” by Manfred Füllsack. Upshot: The target article defends the fundamental role of circularity for systems sciences and the necessity to develop a conceptual and methodological approach to it. The concept of circularity, however, is multifarious, and two of the main challenges in this respect are to provide distinctions between different forms of circularities and explore in detail the roles they play in organizations. This commentary provides some suggestions in this direction (...)
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