These preprints were automatically compiled into a PDF from the collection of papers deposited in PhilSci-Archive in conjunction with the PSA 2018.

Philosophical investigation in synthetic biology has focused on the knowledge-seeking questions pursued, the kind of engineering techniques used, and on the ethical impact of the products produced. However, little work has been done to investigate the processes by which these epistemological, metaphysical, and ethical forms of inquiry arise in the course of synthetic biology research. An attempt at this work relying on a particular area of synthetic biology will be the aim of this chapter. I focus on the reengineering of (...) metabolic pathways through the manipulation and construction of small DNA-based devices and systems synthetic biology. Rather than focusing on the engineered products or ethical principles that result, I will investigate the processes by which these arise. As such, the attention will be directed to the activities of practitioners, their manipulation of tools, and the use they make of techniques to construct new metabolic devices. Using a science-in-practice approach, I investigate problems at the intersection of science, philosophy of science, and sociology of science. I consider how practitioners within this area of synthetic biology reconfigure biological understanding and ethical categories through active modelling and manipulation of known functional parts, biological pathways for use in the design of microbial machines to solve problems in medicine, technology, and the environment. We might describe this kind of problem-solving as relying on what Helen Longino referred to as “social cognition” or the type of scientific work done within what Hasok Chang calls “systems of practice”. My aim in this chapter will be to investigate the relationship that holds between systems of practice within metabolic engineering research and social cognition. I will attempt to show how knowledge and normative valuation are generated from this particular network of practitioners. In doing so, I suggest that the social nature of scientific inquiry is ineliminable to both knowledge acquisition and ethical evaluations. (shrink)

Philosophy strives to give us a firmer hold on our concepts. But what about their hold on us? Why place ourselves under the sway of a concept and grant it the authority to shape our thought and conduct? Another conceptualization would carry different implications. What makes one way of thinking better than another? This book develops a framework for concept appraisal. Its guiding idea is that to question the authority of concepts is to ask for reasons of a special kind: (...) reasons for concept use, which tell us which concepts to adopt, adhere to, or abandon, thereby shoring up—or undercutting—the reasons for action and belief that guide our deliberations. Traditionally, reasons for concept use have been sought either in timeless rational foundations or in concepts’ inherent virtues, such as precision and consistency. Against this, the book advances two main claims: that we find reasons for concept use in the conceptual needs we discover when we critically distance ourselves from a concept by viewing it from the autoethnographic stance; and that sometimes, concepts that conflict, or exhibit other vices such as vagueness or superficiality, are just what we need. By considering not what concepts are absolutely best, but what concepts we now need, we can reconcile ourselves to the contingency of our concepts, determine the proper place of efforts to tidy up thought, and adjudicate between competing conceptions of things—even things as contested as liberty or free will. A needs-based approach separates helpful clarification from hobbling tidy-mindedness, and authoritative definition from conceptual gerrymandering. (shrink)

We develop a methodological framework to develop process theories on routines by leveraging large volumes of digital trace data following critical realism principles. Our framework begins with collecting and preprocessing digital trace data, corresponding to the empirically observed experience of critical realism. In the second and third steps of the framework, we identify a finite set of similar repetitive patterns (routines) through computational analysis. We accomplish this by combining frequent subsequence mining and clustering analysis to transform empirical observation into a (...) set of routines that correspond to actual happening in critical realism. Then, we employ a retroduction approach to identify generative mechanisms of the routines. In the final step, we validate the generative mechanisms by evaluating proposed processual explanations and/or eliminating alternatives. We provide an illustrative example of developing a process theory in relation to the collaboration pattern in Wikipedia. (shrink)

This paper examines the role existence plays in measurement validity. I argue that existing popular theories of measurement and of validity follow a correspondence framework, which starts by assuming that an entity exists in the real world with certain properties that allow it to be measurable. Drawing on literature from the sociology of measurement, I show that the correspondence framework faces several theoretical and practical challenges. I suggested the validity-first framework of measurement, which starts with a practice-based validation process as (...) the basis for a measurement theory, and only posits objective existence when it is scientifically useful to do so. (shrink)

Our aim in this article is to show how the theory of conceptual spaces can be useful in describing diachronic changes to conceptual frameworks, and thus useful in understanding conceptual change in the empirical sciences. We also compare the conceptual space approach to Moulines’s typology of intertheoretical relations in the structuralist tradition. Unlike structuralist reconstructions, those based on conceptual spaces yield a natural way of modeling the changes of a conceptual framework, including noncumulative changes, by tracing the changes to the (...) dimensions that reconstitute a conceptual framework. As a consequence, the incommensurability of empirical theories need not be viewed as a matter of conceptual representation. (shrink)

By understanding laws of nature as geometrical rather than linguistic entities, this paper addresses how to describe theory structures and how to evaluate their continuity. Relying on conceptual spaces as a modelling tool, we focus on the conceptual framework an empirical theory presupposes, thus obtain a geometrical representation of a theory’s structure. We stress the relevance of measurement procedures in separating conceptual from empirical structures. This lets our understanding of scientific laws come closer to scientific practice, and avoids a widely (...) recognised deficit in current philosophy of science accounts, namely to risk a collapse of the physical into the mathematical. (shrink)

Embodied and extended cognition is a relatively new paradigm within cognitive science that challenges the basic tenet of classical cognitive science, viz. cognition consists in building and manipulating internal representations. Some of the pioneers of embodied cognitive science have claimed that this new way of conceptualizing cognition puts pressure on epistemological and ontological realism. In this paper I will argue that such anti-realist conclusions do not follow from the basic assumptions of radical embodied cognitive science. Furthermore I will show that (...) one can develop a form of realism that reflects rather than just accommodates the core principles of non-representationalist embodied cognitive science. (shrink)

Francis Ysidro Edgeworth’s unduly neglected monograph New and Old Methods of Ethics (1877) advances a highly sophisticated and mathematized account of social well-being in the utilitarian tradition of his 19th-century contemporaries. This article illustrates how his usage of the ‘calculus of variations’ was combined with findings from empirical psychology and economic theory to construct a consequentialist axiological framework. A conclusion is drawn that Edgeworth is a methodological predecessor to several important methods, ideas, and issues that continue to be discussed in (...) contemporary social well-being studies. (shrink)

Archaeological data are shadowy in a number of senses. Not only are they notoriously fragmentary but the conceptual and technical scaffolding on which archaeologists rely to constitute these data as evidence can be as constraining as it is enabling. A recurrent theme in internal archaeological debate is that reliance on sedimented layers of interpretative scaffolding carries the risk that “preunderstandings” configure what archaeologists recognize and record as primary data, and how they interpret it as evidence. The selective and destructive nature (...) of data capture in archeology further suggests that there may be little scope for putting “legacy” data to work in new ways. And yet archaeologists have been strikingly successful in mining old datasets for new insights. I situate these concerns in the broader context of debate about the epistemic standing of the historical sciences, and then consider three strategies by which archaeologists address the challenges posed by legacy data. The first two – secondary retrieval and recontextualization – are a matter of reconfiguring the scaffolding that underpins evidential reasoning. The third turns on redeploying old data in the context of computational models that support the experimental simulation of the cultural systems and contexts under study. (shrink)

This paper provides a restatement and defense of the data/ phenomena distinction introduced by Jim Bogen and me several decades ago (e.g., Bogen and Woodward, The Philosophical Review, 303–352, 1988). Additional motivation for the distinction is introduced, ideas surrounding the distinction are clarified, and an attempt is made to respond to several criticisms.

Millikan's famous oil drop experiment is scrutinized from the viewpoint of the methodological dicta of the credibility revolution.

In this paper we argue that the difference between standard measurement and proxy measurement in paleoclimatology should not be understood in terms of ‘directness’. Measurements taken by climatologists to be paradigmatically non-proxy exhibit the kinds of indirectness that are thought to separate them proxy measurement. Rather, proxy measurements and standard measurements differ in how they account for confounding causal factors. Measurements are ‘proxy’ to the extent that the measurements require vicarious controls, while measurements are not proxy, but rather ‘standard’, to (...) the extent that the measurement apparatus provides sufficient physical control on its own. Guided by this account of proxy measurement, we then consider some of the challenges specific to historical proxy measurement and how it is that historical scientists address these challenges. Historical scientists rely on significant causal dependencies and naturally preserved signals to mitigate the influence of destructive processes over time. (shrink)

Several scholars observed that narratives about the human past are evaluated comparatively. Few attempts have been made, however, to explore how such evaluations are actually done. Here I look at a lengthy “contest” among several historiographic narratives, all constructed to make sense of another one—the biblical story of the conquest of Canaan. I conclude that the preference of such narratives can be construed as a rational choice. In particular, an easily comprehensible and emotionally evocative narrative will give way to a (...) complex and mundane one, when the latter provides a more coherent account of the consensually accepted body of evidence. This points to a fundamental difference between historiographic narratives and fiction, contrary to some influential opinions in the philosophy of historiography. Such historiographic narratives have similarities with hypotheses and narrative explanations in natural science. (shrink)

The project of integrated HPS has occupied philosophers of science in one form or another since at least the 1960s. Yet, despite this substantial interest in bringing together philosophical and historical reflections on the nature of science, history of science and formal philosophy of science remain as divided as ever. In this paper, I will argue that the continuing separation between historical and formal philosophy of science is ill-founded. I will argue for this in both abstract and concrete terms. At (...) the abstract level, I reconstruct two possible arguments for the incompatibility of historical and formal philosophy of science and argue that they are both wanting. At the concrete level, I discuss how historical and formal philosophy of science have been brought together in practice, namely: in the form of a largely forgotten research tradition that I will refer to here as the study of formalized macro-units. After a brief exposition, I argue that this research tradition has been unduly overlooked by historically minded philosophers of science. Bringing together these observations, I argue that the divide between historical and formal philosophy of science is not grounded in any substantive arguments, but can be primarily attributed to disciplinary happenstance. (shrink)

The term " technoscience " gained philosophical significance in the 1970s but it aroused ambivalent views. On the one hand, several scholars have used it to shed light on specific features of recent scientific research, especially with regard to emerging technologies that blur boundaries (such as natural/artificial, machine/living being, knowing/making and so on); on the other hand, as a matter of fact " technoscience " did not prompt great interest among philosophers. In the French area, a depreciative meaning prevails: " (...) technoscience " means the contamination of science by management and capitalism. Some even argue that " technoscience " is not a concept at all, just a buzzword. In this chapter, on the contrary, we make the case for the constitution of a philosophical concept of technoscience based on the characterization of its objects in order to scrutinize their epistemological, ontological, political and ethical dimensions. (shrink)

Psychometrics and the representational theory of measurement are widely used in social scientific measurement. They are currently pursued largely in isolation from one another. I argue that despite their separation in practice, RTM and psychometrics are complementary approaches, because they can contribute in complementary ways to the establishment of what I argue is a crucial measurement property, namely, representational interpretability. Because RTM and psychometrics are complementary in the establishment of representational interpretability, the current separation of measurement approaches is unfounded. 1Introduction2Two (...) Approaches to Measurement 2.1Representational theory of measurement2.2Psychometrics2.3Representational interpretability3Complementarity, Conceptually 3.1Representational theory of measurement: Conditions of representational interpretability3.2Psychometrics: Evidence of representational interpretability4Complementarity in Action 4.1What is the Rasch model?4.2Rasch and conjoint measurement5Conclusion: Critics and Fruits of Complementarity. (shrink)

Erik Angner has argued that simultaneous endorsement of the representational theory of measurement and psychometrics leads to inconsistency. His claim rests on an implicit assumption: RTM and psychometrics are full-fledged approaches to measurement. I argue that RTM and psychometrics are only partial approaches that deal with different aspects of measurement, and that therefore simultaneous endorsement of the two is not inconsistent. The argument has implications for the improvement of measurement practices.

The Representational Theory of Measurement is the best known account of the kind of representation measurement requires. However, RTM has been challenged from various angles, with critics claiming e.g. that RTM fails to account for actual measurement practice and that it is ambiguous about the nature of measurable attributes. In this paper I use the critical literature on RTM to formulate Representation Minimalism – a characterization of what measurement-relevant representation requires at the minimum. I argue that Representation Minimalism avoids the (...) main problems with RTM while acknowledging its usefulness as the formal foundation of representation in measurement. (shrink)

Understanding nature of science is widely considered an important educational objective and views of NOS are closely linked to science teaching and learning. Thus there is a lively discussion about what understanding NOS means and how it is reached. As a result of analyses in educational, philosophical, sociological and historical research, a worldwide consensus about the content of NOS teaching is said to be reached. This consensus content is listed as a general statement of science, which students are supposed to (...) understand during their education. Unfortunately, decades of research has demonstrated that teachers and students alike do not possess an appropriate understanding of NOS, at least as far as it is defined at the general level. One reason for such failure might be that formal statements about the NOS and scientific knowledge can really be understood after having been contextualized in the actual cases. Typically NOS is studied as contextualized in the reconstructed historical case stories. When the objective is to educate scientifically and technologically literate citizens, as well as scientists of the near future, studying NOS in the contexts of contemporary science is encouraged. Such contextualizations call for revision of the characterization of NOS and the goals of teaching about NOS. As a consequence, this article gives two examples for studying NOS in the contexts of scientific practices with practicing scientists: an interview study with nanomodellers considering NOS in the context of their actual practices and a course on nature of scientific modelling for science teachers employing the same interview method as a studying method. Such scrutinization opens rarely discussed areas and viewpoints to NOS as well as aspects that practising scientists consider as important. (shrink)

This paper applies conceptual engineering to deal with four objections that have been levelled against operationalism in psychology. These objections are: operationalism leads to harmful proliferation of concepts, operationalism goes hand-in-hand with untenable antirealism, operationalism leads to arbitrariness in scientific concept formation, and operationalism is incompatible with the usual conception of scientific measurement. Relying on a formulation of three principles of conceptual engineering, I will argue that there is a useful form of operationalism that does not fall prey to these (...) four objections. (shrink)

The frequent occurrence of comorbidity has brought about an extensive theoretical debate in psychiatry. Why are the rates of psychiatric comorbidity so high and what are their implications for the ontological and epistemological status of comorbid psychiatric diseases? Current explanations focus either on classification choices or on causal ties between disorders. Based on empirical and philosophical arguments, we propose a conventionalist interpretation of psychiatric comorbidity instead. We argue that a conventionalist approach fits well with research and clinical practice and resolves (...) two problems for psychiatric diseases: experimenter’s regress and arbitrariness. (shrink)

The Credit Theory of Knowledge (CTK)—as expressed by such figures as John Greco, Wayne Riggs, and Ernest Sosa—holds that knowing that p implies deserving epistemic credit for truly believing that p . Opponents have presented three sorts of counterexamples to CTK: S might know that p without deserving credit in cases of (1) innate knowledge (Lackey, Kvanvig); (2) testimonial knowledge (Lackey); or (3) perceptual knowledge (Pritchard). The arguments of Lackey, Kvanvig and Pritchard, however, are effective only in so far as (...) one is willing to accept a set of controversial background assumptions (for instance, that innate knowledge exists or that doxastic voluntarism is wrong). In this paper I mount a fourth argument against CTK, that doesn’t rest on any such controversial premise, and therefore should convince a much wider audience. In particular, I show that in cases of extended cognition (very broadly conceived), the most salient feature explaining S ’s believing the truth regarding p may well be external to S , that is, it might be a feature of S ’s (non-human, artifactual) environment. If so, the cognitive achievement of knowing that p is not (or only marginally) creditable to S , and hence, CTK is false. (shrink)

The history of the luminiferous ether is sketched with a view to ascertaining what factors may have kept this idea alive until 1905, when Einstein declared it superfluous.

Bruno Latour, as part of his advocacy of science studies urges us to move beyond what he calls ‘the Modernist Settlement’ that, among other things, separated science from politics and subject from object. As part of this project he has frequently called for the abolition of epistemology, including quite specifically the historical epistemology/epistemological history of Gaston Bachelard and Georges Canguilhem. Pierre Bourdieu, on the other hand, deploys the resources of historical epistemology, to dismiss Latour’s science studies. After examining the charges (...) against historical epistemology and their rebuttal, I rule in favor of the defense. However, I also suggest that Latour raises genuine concerns about how to equip ourselves to tackle problems such as those associated with climate change; these are problems that require engagement with the politics of nature, with the politics of the sciences of nature and with the epistemological challenges associated with the need to deploy multiple disciplines in the service of complex, practical, policy-relevant problem solving. (shrink)

The historical debate on representation in cognitive science and neuroscience construes representations as theoretical posits and discusses the degree to which we have reason to posit them. We reject the premise of that debate. We argue that experimental neuroscientists routinely observe and manipulate neural representations in their laboratory. Therefore, neural representations are as real as neurons, action potentials, or any other well-established entities in our ontology.

Explanatory realism is the position that all explanations give information about whatever metaphysically determines the explanandum. This view is popular and plays a central role in metaphysics, but in this paper I argue that explanatory realism is false. In Sect. 1 I introduce explanatory realism in its weak and strong versions, and discuss the argumentative work that explanatory realism is used for in contemporary metaphysics. In Sect. 2 I present a series of problem cases for explanatory realism, including explanation by (...) analogy, explanations involving rules, reduction ad absurdum explanations and certain statistical explanations. In Sect. 3 I consider and reject two modified versions of explanatory realism: the position that explanatory realism is true only of explanation in metaphysics, and the position that determinative explanation is the most complete form of explanation. In conclusion I consider explanatory antirealism and explanatory pluralism as alternatives to explanatory realism. (shrink)

This paper has a twofold purpose. First, it aims at highlighting one difference in how counterfactuals work in general history, on the one hand, and in history of the natural sciences, on the other hand. As we show, both in general history and in history of science good counterfactual narratives need to be plausible, where plausibility is construed as appropriate continuity of both the antecedent and the consequent of the counterfactual with what we know about the world. However, in general (...) history it is often possible to imagine a consequent dramatically different from the actual historical development, and yet plausible; in history of science, due to plausibility concerns, imagining a consequent far removed from the results of actual science seems more complicated. The second aim of the paper is to assess whether and to what degree counterfactual histories of science can advance the cause of the so-called “contingency thesis,” namely, the claim that history of science might have followed a path leading to alternative, non-equivalent theories, as successful as the ones that we currently embrace. We distinguish various versions of the contingency thesis and argue that counterfactual histories of science support weak versions of the thesis. (shrink)

The philosophy of measurement studies the conceptual, ontological, epistemic, and technological conditions that make measurement possible and reliable. A new wave of philosophical scholarship has emerged in the last decade that emphasizes the material and historical dimensions of measurement and the relationships between measurement and theoretical modeling. This essay surveys these developments and contrasts them with earlier work on the semantics of quantity terms and the representational character of measurement. The conclusions highlight four characteristics of the emerging research program in (...) philosophy of measurement: it is epistemological, coherentist, practice oriented, and model based. (shrink)

This article develops a model-based account of the standardization of physical measurement, taking the contemporary standardization of time as its central case study. To standardize the measurement of a quantity, I argue, is to legislate the mode of application of a quantity concept to a collection of exemplary artefacts. Legislation involves an iterative exchange between top-down adjustments to theoretical and statistical models regulating the application of a concept, and bottom-up adjustments to material artefacts in light of remaining gaps. The model-based (...) account clarifies the cognitive role of ad hoc corrections, arbitrary rules, and seemingly circular inferences involved in contemporary timekeeping, and explains the stability of networks of standards better than its conventionalist and constructivist counterparts. 1 Introduction2 Making Time Universal2.1 Stability and accuracy2.2 Multiple realizability2.3 The challenges of synchronicity2.4 Divergent standards2.5 The leap second3 The Two Faces of Stability3.1 An explanatory challenge3.2 Conventionalist explanations3.3 Constructivist explanations4 Models and Standardization4.1 A third alternative4.2 Stability reconceived4.3 Legislative freedom4.4 Discovering gaps4.5 Nature and society entangled4.6 Remark on scope5 Conclusions. (shrink)

When discrepancies are discovered between the outcomes of different measurement procedures, two sorts of explanation are open to scientists. Either some of the outcomes are inaccurate or the procedures are not measuring the same quantity. I argue that, due to the possibility of systematic error, the choice between and is underdetermined in principle by any possible evidence. Consequently, foundationalist criteria of quantity individuation are either empty or circular. I propose a coherentist, model-based account of measurement that avoids the underdetermination problem, (...) and use this account to explain how scientists individuate quantities in practice. (shrink)

This paper draws attention to an increasingly common method of using computer simulations to establish evidential standards in physics. By simulating an actual detection procedure on a computer, physicists produce patterns of data (‘signatures’) that are expected to be observed if a sought-after phenomenon is present. Claims to detect the phenomenon are evaluated by comparing such simulated signatures with actual data. Here I provide a justification for this practice by showing how computer simulations establish the reliability of detection procedures. I (...) argue that this use of computer simulation undermines two fundamental tenets of the Bogen–Woodward account of evidential reasoning. Contrary to Bogen and Woodward’s view, computer-simulated signatures rely on ‘downward’ inferences from phenomena to data. Furthermore, these simulations establish the reliability of experimental setups without physically interacting with the apparatus. I illustrate my claims with a study of the recent detection of the superfluid-to-Mott-insulator phase transition in ultracold atomic gases. (shrink)

The Morris water maze has been put forward in the philosophy of neuroscience as an example of an experimental arrangement that may be used to delineate the cognitive faculty of spatial memory (e.g., Craver and Darden, Theory and method in the neurosciences, University of Pittsburgh Press, Pittsburgh, 2001; Craver, Explaining the brain: Mechanisms and the mosaic unity of neuroscience, Oxford University Press, Oxford, 2007). However, in the experimental and review literature on the water maze throughout the history of its use, (...) we encounter numerous responses to the question of “what” phenomenon it circumscribes ranging from cognitive functions (e.g., “spatial learning”, “spatial navigation”), to representational changes (e.g., “cognitive map formation”) to terms that appear to refer exclusively to observable changes in behavior (e.g., “water maze performance”). To date philosophical analyses of the water maze have not been directed at sorting out what phenomenon the device delineates nor the sources of the different answers to the question of what. I undertake both of these tasks in this paper. I begin with an analysis of Morris’s first published research study using the water maze and demonstrate that he emerged from it with an experimental learning paradigm that at best circumscribed a discrete set of observable changes in behavior. However, it delineated neither a discrete set of representational changes nor a discrete cognitive function. I cite this in combination with a reductionist-oriented research agenda in cellular and molecular neurobiology dating back to the 1980s as two sources of the lack of consistency across the history of the experimental and review literature as to what is under study in the water maze. (shrink)

The past decade has witnessed a growing awareness of conceptual and methodological hurdles within psychology and neuroscience that must be addressed for taxonomic and explanatory progress in understanding psychological functions to be possible. In this paper, I evaluate several recent knowledge-building initiatives aimed at overcoming these obstacles. I argue that while each initiative offers important insights about how to facilitate taxonomic and explanatory progress in psychology and neuroscience, only a “coordinated pluralism” that incorporates positive aspects of each initiative will have (...) the potential for success. (shrink)

Consensus conferences are social techniques which involve bringing together a group of scientific experts, and sometimes also non-experts, in order to increase the public role in science and related policy, to amalgamate diverse and often contradictory evidence for a hypothesis of interest, and to achieve scientific consensus or at least the appearance of consensus among scientists. For consensus conferences that set out to amalgamate evidence, I propose three desiderata: Inclusivity, Constraint, and Evidential Complexity. Two examples suggest that consensus conferences can (...) readily satisfy Inclusivity and Evidential Complexity, but consensus conferences do not as easily satisfy Constraint. I end by discussing the relation between social inclusivity and the three desiderata. (shrink)

In this opinion piece, the authors offer their personal and idiosyncratic views of the future of the philosophy of science, focusing on its relationship with the history of science and metaphysics, respectively. With regard to the former, they suggest that the Kantian tradition might be drawn upon both to render the history and philosophy of science more relevant to philosophy as a whole and to overcome the challenges posed by naturalism. When it comes to the latter, they suggest both that (...) metaphysics has much to learn from the philosophy of science and that it offers an array of tools that philosophers of science can themselves appropriate. (shrink)

This paper deals with calibration in scientific practices which investigate relatively well-understood natural phenomena by means of already standardized instrumental devices. Calibration is a crucial topic, since it conditions the reliability of instrumental procedures in science. Yet although important, calibration is a relatively neglected topic. We think more attention should be devoted to calibration. The paper attempts to take a step in this direction. The aims are two-fold: (1) to characterize calibration in a relatively simple kind of scientific practices; (2) (...) to provide conceptual and taxonomic tools of broader scope that help to get a better understanding of calibration in more complex cases and other kinds of scientific practices. For this purpose, we first provide indications for why a conceptual framework is needed. Second, a bibliographic survey of works dealing with calibration is attempted. Third, we introduce different tools to enable a better understanding of calibration. Fourth, we turn to the elaboration of what we call a “simple exemplar” of calibration, illustrated through the case of the calibration of an equal-arm balance. Fifth, the tools previously introduced, and the framework of the simple exemplar, are applied to a more complex case of calibration: calibration procedures in X-ray experiments. This serves to show the work accomplished by the simple exemplar and to emphasize features of more complex cases of calibration. Eventually, we revisit and specify the nature, status, scope and value of the proposed framework. (shrink)

Is there anything more to temperature than the ordering of things from colder to hotter? Are there also facts, for example, about how much hotter (twice as hot, three times as hot...) one thing is than another? There certainly are---but the only strong justification for this claim comes from statistical mechanics. What we knew about temperature before the advent of statistical mechanics (what we knew about it from thermodynamics) provided only weak reasons to believe it.

Philosophers are divided on whether the proof- or truth-theoretic approach to logic is more fruitful. The paper demonstrates the considerable explanatory power of a truth-based approach to logic by showing that and how it can provide (i) an explanatory characterization —both semantic and proof-theoretical—of logical inference, (ii) an explanatory criterion for logical constants and operators, (iii) an explanatory account of logic’s role (function) in knowledge, as well as explanations of (iv) the characteristic features of logic —formality, strong modal force, generality, (...) topic neutrality, basicness, and (quasi-)apriority, (v) the veridicality of logic and its applicability to science, (v) the normativity of logic, (vi) error, revision, and expansion in/of logic, and (vii) the relation between logic and mathematics. The high explanatory power of the truth-theoretic approach does not rule out an equal or even higher explanatory power of the proof-theoretic approach. But to the extent that the truth-theoretic approach is shown to be highly explanatory, it sets a standard for other approaches to logic, including the proof-theoretic approach. (shrink)

Statistical mechanics is a strange theory. Its aims are debated, its methods are contested, its main claims have never been fully proven, and their very truth is challenged, yet at the same time, it enjoys huge empirical success and gives us the feeling that we understand important phenomena. What is this weird theory, exactly? Statistical mechanics is the name of the ongoing attempt to apply mechanics, together with some auxiliary hypotheses, to explain and predict certain phenomena, above all those described (...) by thermodynamics. This paper shows what parts of this objective can be achieved with mechanics by itself. It thus clarifies what roles remain for the auxiliary assumptions that are needed to achieve the rest of the desiderata. Those auxiliary hypotheses are described in another paper in this journal, Foundations of statistical mechanics: The auxiliary hypotheses. (shrink)

It is now well-appreciated by philosophers that contemporary large-scale ‘-omics’ studies in biology stand in non-trivial relationships to more orthodox hypothesis-driven approaches. These relationships have been clarified by Ratti (2015); however, there remains much more to be said regarding how an important field of genomics cited in that work—‘genome-wide association studies’ (GWAS)—fits into this framework. In the present article, we propose a revision to Ratti’s framework more suited to studies such as GWAS. In the process of doing so, we introduce (...) to the philosophical literature novel exploratory experiments in (phospho)proteomics, and demonstrate how these experiments interplay with the above considerations. (shrink)

In this article I argue that a methodological challenge to an integrated history and philosophy of science approach put forth by Ronald Giere almost forty years ago can be met by what I call the Kuhnian mode of History and Philosophy of Science (HPS). Although in the Kuhnian mode of HPS norms about science are motivated by historical facts about scientific practice, the justifiers of the constructed norms are not historical facts. The Kuhnian mode of HPS therefore evades the naturalistic (...) fallacy which Giere’s challenge is a version of. Against the backdrop of a discussion of Laudan’s normative naturalism I argue that the Kuhnian mode of HPS is a superior form of naturalism: it establishes contact to the practice of science without making itself dependent on its contingencies. (shrink)

In recent years there has been a revival of the debate about the relation between history and philosophy of science. This article seeks to contribute to the discussion by approaching the issue from a new angle. To rethink the relation between the two domains of study, I apply an important insight about scientific practice to the practice of integrating the history and philosophy of science: the insight that the scientific paper does not give a faithful account of the actual research (...) pursued in the laboratory or in the field. Arguably, the scholarly article about science is also not a transparent window to the activity of producing such an article. But if it is not, we need to redirect our attention. If we want to understand the nature and merits of integrating the history and philosophy of science, we need to examine both the actual activity of integrating and the scholarly paper produced by it. To consider what one can learn from such an inquiry, I reflect on my own activity of studying scientific justification through the combination of historical and philosophical analysis. Probing a concrete historical episode, micro-anatomical research on the retina in the 19th century, I pursue two related questions, the first-order question, 'What exactly is scientific justification in the given case?' and the meta-question, 'How do I go about analysing justificatory practices?' I then characterise the nature of my analysis and consider what can be learned from the study of the practice of integrating the history and philosophy of science. (shrink)

Economists study "The Economy," or so one might suppose. Yet this overarching entity is strikingly absent from mainstream theory. Since the 1950s, it has generally been described with a few mathematical propositions and not given a description that attends to institutions, power relations, or the emergent properties that form the leading indicators in macroeconomic theory. There is thus a significant divergence between folk economics and scientific economics on this theoretical entity. This article briefly addresses the history of this concept, noting (...) its heyday in the interwar years, and brings to bear some of the analytical apparatus on institutional facts devised by John Searle. Whatever is meant by "The Economy" in folk economics appears to be significantly divergent from what is posited in scientific economics. Key Words: economy • Searle • theoretical entities • macroeconomics • economic indicators • folk economics. (shrink)