Observation and experiment as categories for analysing scientific practice have a long pedigree in writings on science. There has, however, been little attempt to delineate observation and experiment with respect to analysing scientific practice; in particular, scientific experimentation, in a systematic manner. Someone who has presented a systematic account of observation and experiment as categories for analysing scientific experimentation is Ian Hacking. In this paper, I present a detailed analysis of Hacking’s observation versus experiment account. Using a range of cases (...) from various fields of scientific enquiry, I argue that the observation versus experiment account is not an adequate framework for delineating scientific experimentation in a systematic manner. (shrink)

In an attempt to determine the epistemic status of computer simulation results, philosophers of science have recently explored the similarities and differences between computer simulations and experiments. One question that arises is whether and, if so, when, simulation results constitute novel empirical data. It is often supposed that computer simulation results could never be empirical or novel because simulations never interact with their targets, and cannot go beyond their programming. This paper argues against this position by examining whether, and under (...) what conditions, the features of empiricality and novelty could be displayed by computer simulation data. I show that, to the extent that certain familiar measurement results have these features, so can some computer simulation results. (shrink)

Life-science phenomena are often explained by specifying the mechanisms that bring them about. The new mechanistic philosophers have done much to substantiate this claim and to provide us with a better understanding of what mechanisms are and how they explain. Although there is disagreement among current mechanists on various issues, they share a common core position and a seeming commitment to some form of scientific realism. But is such a commitment necessary? Is it the best way to go about mechanistic (...) explanation? In this article, we propose an alternative antirealist account that also fits explanatory practice in the life sciences. We pay special attention to mechanistic models, i.e. scientific models that involve a mechanism, and to the role of coherence considerations in building such models. To illustrate our points, we consider the mechanism for the action potential. 1 Introduction2 Some Core Features of Mechanistic Explanation3 Scientific Realism and Mechanistic Explanation4 Antirealist Mechanistic Explanation: The Case of the Action Potential5 Some Outstanding Issues for the Antirealist Mechanist6 Two Problems for the Realist Mechanist7 Conclusions. (shrink)

This article discusses the relation between features of empirical data and structures in the world. I defend the following claims. Any empirical data set exhibits all possible patterns, each with a certain noise term. The magnitude and other properties of this noise term are irrelevant to the evidential status of a pattern: all patterns exhibited in empirical data constitute evidence of structures in the world. Furthermore, distinct patterns constitute evidence of distinct structures in the world. It follows that the world (...) must be regarded as containing all possible structures. The remainder of the article is devoted to elucidating the meaning and implications of the latter claim. (shrink)

This dissertation draws upon historical studies of scientific practice and contemporary issues in the metaphysics and epistemology of science to account for the nature of physical quantities. My dissertation applies this integrated HPS approach to dimensional analysis—a logic for quantitative physical equations which respects the distinct dimensions of quantities (e.g. mass, length, charge). Dimensional analysis and its historical development serve both as subjects of study and as a sources for solutions to contemporary problems. The dissertation consists primarily of three related (...) papers on: (1) the methodological and metaphysical foundations of dimensional analysis, (2) the use of dimensional analysis in determining physical symmetries, (3) the use of dimensional analysis in securing metrological extension. (shrink)

This paper aims to develop an account of the pursuitworthiness of models based on a view of models as epistemic tools. This paper is motivated by the historical question of why, in the 1960s, when many scientists hardly found QSAR models attractive, some pharmaceutical scientists pursued Quantitative Structure–Activity Relationship (QSAR) models despite the lack of potential for theoretical development or empirical success. This paper addresses this question by focusing on how models perform their heuristic functions as epistemic tools rather than (...) as potential theories. I argue that models perform their heuristic function by “constructing” phenomena from data in the sense that they allow the model users who interact with the medium of the models to recognise the phenomena as such. The constructed phenomena assist model users in identifying which conditional hypotheses that are focused on low-level regularities concerning entities such as chemical compounds are more “testworthy,” a concept that links the costs associated with hypothesis testing with the fertility of the hypothesis. (shrink)

According to a widely held view, scientific modelling consists in entertaining a set of model descriptions that specify a model. Rather than studying the phenomenon of interest directly, scientists investigate the phenomenon indirectly via a model in the hope of learning about some of the phenomenon’s features. I call this view the description-driven modelling (DDM) account. I argue that although an accurate description of much of scientific research, the DDM account is found wanting as regards the mechanistic modelling found in (...) many branches of biology. By analysing research practices in cancer immunology concerning the development of mechanistic models of the process of cancer metastasis, this paper presents and argues for a complementary account of scientific modelling, herein called the experimentation-driven modelling (EDM) account. In EDM, scientists investigate a set of experimental systems and then integrate the results obtained from experiments into a mechanistic model. While EDM shares some key features with DDM, the two are epistemically very different approaches to research. (shrink)

There is a deeply entrenched view in philosophy and physics, the closed systems view, according to which isolated systems are conceived of as fundamental. On this view, when a system is under the influence of its environment this is described in terms of a coupling between it and a separate system which taken together are isolated. We argue against this view, and in favor of the alternative open systems view, for which systems interacting with their environment are conceived of as (...) fundamental, and the environment's influence is represented via the dynamical equations that govern the system's evolution. Taking quantum theories of closed and open systems as our case study, and considering three alternative notions of fundamentality: (i) ontic fundamentality, (ii) epistemic fundamentality, and (iii) explanatory fundamentality, we argue that the open systems view is fundamental, and that this has important implications for the philosophy of physics, the philosophy of science, and for metaphysics. (shrink)

This groundbreaking, open access volume analyses and compares data practices across several fields through the analysis of specific cases of data journeys. It brings together leading scholars in the philosophy, history and social studies of science to achieve two goals: tracking the travel of data across different spaces, times and domains of research practice; and documenting how such journeys affect the use of data as evidence and the knowledge being produced. The volume captures the opportunities, challenges and concerns involved in (...) making data move from the sites in which they are originally produced to sites where they can be integrated with other data, analysed and re-used for a variety of purposes. The in-depth study of data journeys provides the necessary ground to examine disciplinary, geographical and historical differences and similarities in data management, processing and interpretation, thus identifying the key conditions of possibility for the widespread data sharing associated with Big and Open Data. The chapters are ordered in sections that broadly correspond to different stages of the journeys of data, from their generation to the legitimisation of their use for specific purposes. Additionally, the preface to the volume provides a variety of alternative “roadmaps” aimed to serve the different interests and entry points of readers; and the introduction provides a substantive overview of what data journeys can teach about the methods and epistemology of research. (shrink)

Intuitively, the future is open and the past fixed: there is something we can do about the future but not the past. Some metaphysicians believe that a proper metaphysics of time must vindicate this intuition. Whereas philosophers have focused on the future and the past, the status of the present remains relatively unexplored. Drawing on resources from action theory, I argue that there is something we can do about the present just like there is something we can do about the (...) future. Hence, a proper metaphysics of the open future should allow for an open present as well. I argue that none of the major metaphysics of the open future currently available can accommodate an open present adequately. Finally, I’ll show that, surprisingly, the shrinking block metaphysics can. (shrink)

This thesis starts with three challenges to the structuralist accounts of applied mathematics. Structuralism views applied mathematics as a matter of building mapping functions between mathematical and target-ended structures. The first challenge concerns how it is possible for a non-mathematical target to be represented mathematically when the mapping functions per se are mathematical objects. The second challenge arises out of inconsistent early calculus, which suggests that mathematical representation does not require rigorous mathematical structures. The third challenge comes from renormalisation group (...) (RG) explanations of universality. It is argued that the structural mapping between the world and a highly abstract minimal model adds little value to our understanding of how RG obtains its explanatory force. I will address the first and second challenges from the similarity perspective. The similarity account captures representations as similarity relations, providing a more flexible and broader conception of representation than structuralism. It is the specification of the respect and degree of similarity that forges mathematics into a context of representation and directs it to represent a specific system in reality. Structuralism is treatable as a tool for explicating similarity rela-tions set-theoretically. The similarity account, combined with other approaches (e.g., Nguyen and Frigg’s extensional abstraction account and van Fraassen’s pragmatic equivalence), can dissolve the first challenge. Additionally, I will make a structuralist response to the second challenge, and suggestions regarding the role of infinitesimals from the similarity perspective. In light of the similarity account, I will propose the “hotchpotch picture” as a method-ological reflection of our study of representation and explanation. Its central insight is to dissect a representation or an explanation into several aspects and use different theories (that are usually thought of competing) to appropriate each of them. Based on the hotchpotch picture, RG explanations can be dissected to the “indexing” and “inferential” conceptions of explanation, which are captured or characterised by structural mappings. Therefore, structuralism accommodates RG explanations, and the third challenge is resolved. (shrink)

There are different narratives on mathematics as part of our world, some of which are more appropriate than others. Such narratives might be of the form ‘Mathematics is useful’, ‘Mathematics is beautiful’, or ‘Mathematicians aim at theorem-credit’. These narratives play a crucial role in mathematics education and in society as they are influencing people’s willingness to engage with the subject or the way they interpret mathematical results in relation to real-world questions; the latter yielding important normative considerations. Our strategy is (...) to frame current narratives of mathematics from a virtue-theoretic perspective. We identify the practice of mathematizing, put forward by Freudenthal’s ‘Realistic mathematics education’, as virtuous and use it to evaluate different narratives. We show that this can help to render the narratives more adequately, and to provide implications for societal organization. (shrink)

The purpose of this article is to develop an epistemology of scientific models in scientific research practices, and to show that disciplinary perspectives have crucial role in such an epistemology. A transcendental approach is taken, aimed at explanations of the kinds of questions relevant to the intended epistemology, such as “How is it possible that models provide knowledge about aspects of reality?” The approach is also pragmatic in the sense that the questions and explanations must be adequate and relevant to (...) concrete scientific practice. First it is explained why the idea of models as representations in terms of similarity or isomorphism between a model and its target is too limited as a basis for this epistemology. An important finding is that the target-phenomenon is usually not something that can be observed in a straightforward manner, but requires both characterization in terms of measurable variables and subsumption under concepts. The loss of this basis leads to a number of issues, such as: how can models be interpreted as representations if models also include conceptually meaningful linguistic content; how can researchers identify non-observable real-world target-phenomena that are then represented in the model; how do models enable inferential reasoning in performing epistemic tasks by researchers; and, how to justify scientific models. My proposal is to deal with these issues by analyzing how models are constructed, rather than by looking at ready-made models. Based on this analysis, I claim that the identification of phenomena and the construction of scientific models is guided and also confined by the disciplinary perspective within which researchers in a scientific discipline have learned to work. I propose a Kuhnian framework by which the disciplinary perspective can be systematically articulated. Finally, I argue that harmful forms of subjectivism, due to the loss of the belief that models objectively represent aspects of reality, can be overcome by making the disciplinary perspective in a research project explicit, thereby enabling its critical assessment, for which the proposed Kuhnian framework provides a tool. (shrink)

Traditionally, empiricism has relied on the specialness of human observation, yet science is rife with sophisticated instrumentation and techniques. The present article advances a conception of empirical evidence applicable to actual scientific practice. I argue that this conception elucidates how the results of scientific research can be repurposed across diverse epistemic contexts: it helps to make sense of how evidence accumulates across theory change, how different evidence can be amalgamated and used jointly, and how the same evidence can be used (...) to constrain competing theories in the service of breaking local underdetermination. (shrink)

The paper rebuts a currently popular criticism against a certain take on the referential role of discontinuities and singularities in the physics of first-order phase transitions. It also elaborates on a proposal I made previously on how to understand this role within the framework provided by the distinction between data and phenomena.

An explanatory gap ensues when the truths constituting the explanans do not entail the explanandum. Attempts to give a physicalist account of consciousness seem to generate an explanatory gap, which is special in the following psychological sense. In other cases, it is possible to bridge or close the gap by regimenting or eliminating the respective concepts. In the case of consciousness, however, there is a pervasive intuition that the gap remains even when one works out a notion of consciousness that (...) allows the entailment of truths about consciousness from physical premises. The intuition is expressed by the sense that something essential about consciousness is left out from any such conceptual regimentation. This paper defends the view that this intuition is generated by the way our experiences are given to us. Every experience has a component that is not captured by any specification. The gap intuition is due to this ineffable component in experiences. Since conscious experiences are partly ineffable, it seems that no account of consciousness captures conscious experiences entirely and so would develop the intuition that something has been left out. An alternative explanation to the gap intuition is provided by the “phenomenal concepts’ strategy”. According to this strategy, it is the peculiar nature of phenomenal concepts that feeds the intuition. The main problem with such an approach is that phenomenal concepts are more coarse-grained than the experiences themselves and thus their application still does not entail what it is like to have a particular phenomenal experience. (shrink)

According to standard (quantum) statistical mechanics, the phenomenon of a phase transition, as described in classical thermodynamics, cannot be derived unless one assumes that the system under study is infinite. This is naturally puzzling since real systems are composed of a finite number of particles; consequently, a well‐known reaction to this problem was to urge that the thermodynamic definition of phase transitions (in terms of singularities) should not be “taken seriously.” This article takes singularities seriously and analyzes their role by (...) using the well‐known distinction between data and phenomena , in an attempt to better understand the origin of the puzzle. *Received April 2009; revised July 2009. †To contact the author, please write to: University of Cambridge, Department of History and Philosophy of Science, Free School Lane, Cambridge CB2 3RH, United Kingdom; e‐mail: [email protected]. (shrink)

Scientists obtain a great deal of the evidence they use by observingnatural and experimentally generated objects and effects. Much of thestandard philosophical literature on this subject comes from20th century logical positivists and empiricists, theirfollowers, and critics who embraced their issues and accepted some oftheir assumptions even as they objected to specific views. Theirdiscussions of observational evidence tend to focus on epistemologicalquestions about its role in theory testing. This entry follows theirlead even though observational evidence also plays important andphilosophically interesting roles (...) in other areas including scientificdiscovery and the application of scientific theories to practicalproblems. (shrink)

I argue that dimensional analysis provides an answer to a skeptical challenge to the theory of model mediated measurement. The problem arises when considering the task of calibrating a novel measurement procedure, with greater range, to the results of a prior measurement procedure. The skeptical worry is that the agreement of the novel and prior measurement procedures in their shared range may only be apparent due to the emergence of systematic error in the exclusive range of the novel measurement procedure. (...) Alternatively: what if the two measurement procedures are not in fact measuring the same quantity? The theory of model mediated measurement can only say that we _assume_ that there is a common quantity. In contrast, I show that the satisfaction of dimensional homogeneity across the metrological extension is independent evidence for the so-called assumption. This is illustrated by the use of dimensional analysis in high pressure experiments. This results in an extension of the theory of model mediated measurement, in which a common quantity in metrological extension is no longer assumed, but hypothesized. (shrink)

What does it take to understand a phenomenon ideally, or to the highest conceivable extent? In this paper, we answer this question by arguing for five necessary conditions for ideal understanding: (i) representational accuracy, (ii) intelligibility, (iii) truth, (iv) reasonable endorsement, and (v) fitting. Even if one disagrees that there is some form of ideal understanding, these five conditions can be regarded as sufficient conditions for a particularly deep level of understanding. We then argue that grasping, novel predictions, and transparency (...) are not reasonable conditions for ideal understanding. (shrink)

When radiocarbon dating techniques were applied to archaeological material in the 1950s they were hailed as a revolution. At last archaeologists could construct absolute chronologies anchored in temporal data backed by immutable laws of physics. This would make it possible to mobilize archaeological data across regions and time-periods on a global scale, rendering obsolete the local and relative chronologies on which archaeologists had long relied. As profound as the impact of 14C dating has been, it has had a long and (...) tortuous history now described as proceeding through three revolutions, each of which addresses distinct challenges of capturing, processing and packaging radiogenic data for use in resolving chronological puzzles with which archaeologists has long wrestled. In practice, mobilizing radiogenic data for archaeological use is a hard-won achievement; it involves multiple transformations that, at each step of the way, depend upon a diverse array of technical expertise and background knowledge. I focus on strategies of triangulation and traceability that establish the integrity of these data and their relevance as anchors for evidential reasoning in archaeology. (shrink)

The notion of empirical adequacy has received recent philosophical attention, especially within the framework of the semantic approach. Empirical adequacy, as explicated in the semantic approach, concerns the relationship between empirical substructures and some phenomena. The aim here is to differentiate this notion of empirical adequacy from one concerning the relationship between data and phenomena. Distinguishing each notion of empirical adequacy emphasizes different aspects of scientific practice—one concerning theory-development from the basis of an established theory, the other concerning theory-development from (...) the basis of data-fitting, where established theory may not foster further development. To illustrate this contrast, an example from financial economics is considered. (shrink)

El presente escrito se propone presentar el modelo de tres niveles del conocimiento científico (datos, fenómenos y teorías) desde los recientes resultados de la filosofía de la ciencia obtenidos por dos perspectivas filosóficas particulares: el nuevo experimentalismo y el enfoque semántico de las teorías. Para ello contrasta los planteamientos principales de estas dos perspectivas con el modelo de dos niveles del conocimiento científico (observación y teoría) del positivismo lógico, que dominó el panorama de la filosofía de la ciencia en las (...) primeras seis décadas del siglo XX. (shrink)

This paper uses several case studies to suggest that (1) two prominent definitions of data do not on their own capture how scientists use data and (2) a novel perspectival account of data is needed. It then outlines some key features of what this account could look like. Those prominent views, the relational and representational, do not fully capture what data are and how they function in science. The representational view is insensitive to the scientific context in which data are (...) used. The relational account does not fully account for the empirical nature of data and how it is possible for data to be evidentially useful. The perspectival account surmounts these problems by accommodating a representational element to data. At the same time, data depend upon the epistemic context because they are the product of situated and informed judgements. (shrink)

Bogen and Woodward’s distinction between data and phenomena raises the need to understand the structure of the data-to-phenomena and theory-to-phenomena inferences. I suggest that one way to study the structure of these inferences is to analyze the role of the assumptions involved in the inferences: What kind of assumptions are they? How do these assumptions contribute to the practice of identifying phenomena? In this paper, using examples from atmospheric dynamics, I develop an account of the practice of identifying the target (...) in the data-to-phenomena and theory-to-phenomena inferences in which assumptions about spatiotemporal scales play a central role in the identification of parameters that describe the target system. I also argue that these assumptions are not only empirical but they are also idealizing and abstracting. I conclude the paper with a reflection on the role of idealizations in modeling. (shrink)

Critics who are concerned over the epistemological status of psychiatric diagnoses often describe them as being constructed. In contrast, those critics usually see symptoms as relatively epistemologically unproblematic. In this paper I show that symptoms are also constructed. To do this I draw upon the demarcation between data and phenomena. I relate this distinction to psychiatry by portraying behaviour of individuals as data and symptoms as phenomena. I then draw upon philosophers who consider phenomena to be constructed to argue that (...) symptoms are also constructed. Rather than being ready made in the world I show how symptoms are constructs we apply to the world. I highlight this with a historical example and describe methodological constraints on symptom construction. I show the epistemic problems with psychiatric diagnoses are also applicable to symptoms. Following this, I suggest that critics of psychiatric diagnoses should extend their criticism to symptoms or, if they still believe symptoms are relatively epistemologically unproblematic, should rethink their concerns over psychiatric diagnoses. (shrink)

Gödel’s first incompleteness theorem is sometimes said to refute mechanism about the mind. §1 contains a discussion of mechanism. We look into its origins, motivations and commitments, both in general and with regard to the human mind, and ask about the place of modern computers and modern cognitive science within the general mechanistic paradigm. In §2 we give a sharp formulation of a mechanistic thesis about the mind in terms of the mathematical notion of computability. We present the argument from (...) Gödel’s theorem against mechanism in terms of this formulation and raise two objections, one of which is known but is here given a more precise formulation, and the other is new and based on the discussion in §1. (shrink)

Reactivity in qualitative data collection occurs when a researcher generates data about a situation with reactivity, that is, a situation in which the ongoing research affects the research participants such that they, say, diverge from their routines when the researcher is present, or tell the researcher what they think she wants to hear. In qualitative research, there are two basic approaches to reactivity. The traditional position maintains that data should ideally be collected in situations without any reactivity. In other words, (...) good data are reactivity free. By contrast, the more recent view holds that data from situations with reactivity are fine as long as the researcher is aware of the occurring reactivity so that she can take it into account when interpreting her data. In this fashion, good data are reactivity transparent. In this paper, I first spell out and defend the more recent approach to reactivity. I argue that qualitative data are reactivity transparent when conjoined with true reactivity assumptions and that, thus supplemented, data are informative about social life independently of its being studied. Next, I examine various issues raised by the requirement to put forth true reactivity assumptions. Lastly, I use my discussion of reactivity transparency as a basis for providing a framework for thinking about good qualitative data. (shrink)

In this paper, I outline a general framework for cultural analysis consistent with an “analytic” approach to explanation in social science. The proposed approach provides coherent solutions to thorny problems in cultural theory. These include providing a coherent definition of culture (and the “cultural”), specifying the nature of cultural units (both simple and complex), and outlining the processes making possible episodes of cultural genesis, transformation, and reproduction within bounded units characterized as cultural causal systems.

Three decades ago, James Bogen and James Woodward argued against the possibility and usefulness of scientific explanations of data. They developed a picture of scientific reasoning where stable phenomena were identified via data without much input from theory. Rather than explain data, theories ‘save the phenomena’. In contrast, I argue that there are good reasons to explain data, and the practice of science reveals attempts to do so. I demonstrate that algorithms employed to address inverse problems in remote-sensing applications should (...) be understood as attempts to identify phenomena by explaining the data. Thus, this paper furthers understanding of data-to-phenomena reasoning in science, and demonstrates theory may play a more central role in phenomena identification than previously recognized. (shrink)

El presente escrito se propone presentar el modelo de tres niveles del conocimiento científico (datos, fenómenos y teorías) desde los recientes resultados de la filosofía de la ciencia obtenidos por dos perspectivas filosóficas particulares: el nuevo experimentalismo y el enfoque semántico de las teorías. Para ello contrasta los planteamientos principales de estas dos perspectivas con el modelo de dos niveles del conocimiento científico (observación y teoría) del positivismo lógico, que dominó el panorama de la filosofía de la ciencia en las (...) primeras seis décadas del siglo XX. (shrink)

Philosophical theories of evidence have been on offer, but they are mostly evaluated in terms of all-or-none desiderata — if they fail to meet one of the desiderata, they are not a satisfactory theory. In this thesis, I aim to accomplish three missions. Firstly, I construct a new way of evaluating theories of evidence, which I call a tool-based view. Secondly, I analyse the nature of what I will call the various relevance-mediating vehicles that each theory of evidence employs. Thirdly, (...) I articulate the comparative core of evidential reasoning in the historical sciences, one which is overlooked in major theories of evidence. On the first mission, I endorse a meta-thesis of pluralism on theories of evidence, namely a tool-based view. I regard a theory of evidence as a purpose-specific and setting-sensitive tool which has its own strengths, difficulties and limitations. Among the major theories of evidence I have reviewed, I focus on Achinstein’s explanationist theory, Cartwright’s argument theory and Reiss’s inferentialist account, scrutinising and evaluating them against the purposes they set out and the scope of their applications. On the second mission, I note that there is no such thing as intrinsically ‘being evidence’. Rather, I hold that relevance-mediating vehicles configure data, materials or claims in such ways that some of them are labelled evidence. I identify the relevance-mediating vehicles that the theories of evidence employ. On the final mission, I argue that the likelihoodist account is an appropriate tool for explaining the evidential reasoning in poorly specified settings where likelihoods can be only imprecisely compared. Such settings, I believe, are typical in the historical sciences. Using the reconstruction of proto-sounds in historical linguistics as a case study, I formalise the rationale behind it by means of the law of likelihood. (shrink)

La tesis de la subdeterminación empírica representa uno de los mayores desafíos contemporáneos en contra del realismo científico, sin embargo, frecuentemente se le ha considerado como un reto coherente y se ha buscado una forma de atenuar su impacto ya sea mitigando alguna posición realista, o bien, atacando alguno de sus presupuestos más problemáticos. En este ensayo defiendo un argumento en su contra, a saber, que es una tesis que nos conduce a una reductio y que semejante resultado echa por (...) tierra su supuesta plausibilidad como una tesis antirrealista. (shrink)

Data production in experimental sciences depends on localised experimental systems, but the epistemic properties of data transcend the contingencies of the processes that produce them. Philosophers often believe that experimental systems instantiate but do not produce the epistemic properties of data. In this paper, we argue that experimental systems' local functioning entails intrinsic capacities to produce the epistemic properties of data. We develop this idea by applying Derrida's model of arche-writing to study a case of theory-oriented experimental practice. Derrida's model (...) relativises or dissolves the conceptual distinction between the moment of data production and a subsequent moment of data dissemination. It thus has consequences for understanding both data production (despite being intrinsically local, data production a priori generates transferrable and modellable information) and data dissemination (when modelling information, researchers needs to refer this information to the context of its production). We study a case of data production in a non-exploratory experimental system designed to test a pre-existing hypothesis in visual neuroscience. A case of theory-oriented experimental practice should allow us to identify the autonomous functioning of experimental systems in data production more clearly, insofar as it allows us to study the limits of pre-existing theory in the activities of these systems. We suggest that pre-existing concepts, hypotheses and theories condition the relevance but not the production of experimental data. (shrink)