The Post-genomic Era includes features both from a methodological and epistemic point of view and from an ontological perspective. Firstly, it incorporates new methods of high-throughput sequencing of DNA and RNA, and the development of complete genomes that allow a precise reference of the molecular results obtained. In addition, from an ontological perspective, the centre of gravity of the molecular processes is placed on the expression of genes, and the way in which such expression is regulated; these features turn the (...) attention towards the study of Gene Regulatory Networks, and in particular to the role of RNA. This new molecular-biological perspective based on new methodologies and approaches is affecting the existing Molecular Genetics Theory including the definition of gen and Central Dogma of Molecular Biology. An important philosophical challenges posed by this new situation is the question whether there is a sophistication of the present theory or a New Theory of Molecular Genetics and whether there is an incommensurability between this theory and the accepted theory. In this work we evaluate these changes in the light of Kuhn’s theory of scientific revolution in order to propose an alternative between a moderate and a strong view. According to the moderate one, the Post-genomic changes do not properly involve a paradigm shift or, if they do, they constitute a minor revolution. The strong view considers that, the anomalies disclosed in the Molecular Genetics Theory at conceptual and methodological level and the Post-genomic changes they lead to suppose a scientific paradigm shift. (shrink)

It is common in various quarters of philosophy to derive philosophically significant conclusions from theories of reference. In this paper, we argue that philosophers should give up on such 'arguments from reference.' Intuitions play a central role in establishing theories of reference, and recent cross-cultural work suggests that intuitions about reference vary across cultures and between individuals within a culture (Machery et al. 2004). We argue that accommodating this variation within a theory of reference undermines arguments from reference.

Simple assumptions represent a decisive reason to prefer one theory to another in everyday scientific praxis. But this praxis has little philosophical justification, since there exist many notions of simplicity, and those that can be defined precisely strongly depend on the language in which the theory is formulated. The language dependence is a natural feature—to some extent—but it is also believed to be a fatal problem, because, according to a common general argument, the simplicity of a theory is always trivial (...) in a suitably chosen language. But, this trivialization argument is typically either applied to toy-models of scientific theories or applied with little regard for the empirical content of the theory. This paper shows that the trivialization argument fails, when one considers realistic theories and requires their empirical content to be preserved. In fact, the concepts that enable a very simple formulation, are not necessarily measurable, in general. Moreover, the inspection of a theory describing a chaotic billiard shows that precisely those concepts that naturally make the theory extremely simple are provably not measurable. This suggests that—whenever a theory possesses sufficiently complex consequences—the constraint of measurability prevents too simple formulations in any language. This explains why the scientists often regard their assessments of simplicity as largely unambiguous. In order to reveal a cultural bias in the scientists’ assessment, one should explicitly identify different characterizations of simplicity of the assumptions that lead to different theory selections. General arguments are not sufficient. (shrink)

The purpose of this article is to show that the customary understanding of epistemic progress as a kind of belief change is incomplete and that conceptual change has to be acknowledged as a crucial driving force in epistemic progress. The author’s argument for the epistemological relevance of conceptual change proceeds as follows. First, he develops an account of conceptual change that clearly distinguishes conceptual change from belief change. He then takes a closer look at two kinds of conceptual change that (...) are of special interest from an epistemological point of view. He calls them “disclosing” conceptual change and “revisionary” conceptual change. He then shows that the idea of epistemic value that demarcates the realm of epistemological inquiry applies to concepts and conceptual change. (shrink)

Science depends on judgments of the bearing of evidence on theory. Scientists must judge whether an observation or the result of an experiment supports, disconfirms, or is simply irrelevant to a given hypothesis. Similarly, scientists may judge that, given all the available evidence, a hypothesis ought to be accepted as correct or nearly so, rejected as false, or neither. Occasionally, these evidential judgments can be made on deductive grounds. If an experimental result strictly contradicts a hypothesis, then the truth of (...) the data deductively entails the falsity of the hypothesis. In the great majority of cases, however, the connection between evidence and hypothesis is non-demonstrative, or inductive. In particular, this is so whenever a general hypothesis is inferred to be correct on the basis of the available data, since the truth of the data will not deductively entail the truth of the hypothesis. It always remains possible that the hypothesis is false even though the data are correct. (shrink)

First published in 2002. Routledge is an imprint of Taylor & Francis, an informa company.

One of the objections against the thesis of underdetermination of theories by observations is that it is unintelligible. Any two empirically equivalent theories — so the argument goes—are in principle intertranslatable, hence cannot count as rivals in any non-trivial sense. Against that objection, this paper shows that empirically equivalent theories may contain theoretical sentences that are not intertranslatable. Examples are drawn from a related discussion about incommensurability that shows that theoretical non-intertranslatability is possible.

In this paper, I propose two theses, and then examine what the consequences of those theses are for discussions of reduction and emergence. The first thesis is that what have traditionally been seen as robust, reductions of one theory or one branch of science by another more fundamental one are a largely a myth. Although there are such reductions in the physical sciences, they are quite rare, and depend on special requirements. In the biological sciences, these prima facie sweeping reductions (...) fade away, like the body of the famous Cheshire cat, leaving only a smile.... The second thesis is that the "smiles" are fragmentary patchy explanations, and though patchy and fragmentary, they are very important, potentially Nobel-prize winning advances. To get the best grasp of these "smiles," I want to argue that, we need to return to the roots of discussions and analyses of scientific explanation more generally, and not focus mainly on reduction models, though three conditions based on earlier reduction models are retained in the present analysis. I briefly review the scientific explanation literature as it relates to reduction, and then offer my account of explanation. The account of scientific explanation I present is one I have discussed before, but in this paper I try to simplify it, and characterize it as involving field elements and a preferred causal model system abbreviated as FE and PCMS. In an important sense, this FE and PCMS analysis locates an "explanation" in a typical scientific research article. This FE and PCMS account is illustrated using a recent set of neurogenetic papers on two kinds of worm foraging behaviors: solitary and social feeding. One of the preferred model systems from a 2002 Nature article in this set is used to exemplify the FE and PCMS analysis, which is shown to have both reductive and nonreductive aspects. The paper closes with a brief discussion of how this FE and PCMS approach differs from and is congruent with Bickle's "ruthless reductionism" and the recently revived mechanistic philosophy of science of Machamer, Darden, and Craver. (shrink)

We reconsider the Nagelian theory of reduction and argue that, contrary to a widely held view, it is the right analysis of intertheoretic reduction. The alleged difficulties of the theory either vanish upon closer inspection or turn out to be substantive philosophical questions rather than knock-down arguments.

Entre los estudios críticos que existen en torno a la obra de Paul Feyerabend predominan aquellos que subrayan una discontinuidad radical entre la versión temprana y tardía de su pensamiento. Todo ello contribuye a que dispongamos de una visión fragmentada e incompleta de un pensador que evoluciono hasta el 1994, año de su fallecimiento. Nuestro propósito es ofrecer una explicación de su itinerario intelectual de tal modo que quedé patente su continuidad en la clave de sus críticas contra los falsos (...) absolutos erigidos por el positivismo lógico y el racionalismo científico. Mostraremos las diversas cuestiones que Feyerabend aborda en las distintas épocas de su vida pero, al mismo tiempo, subrayaremos la unidad o coherencia lógica que existe en su revisión crítica de la racionalidad científica. Nos preocuparemos por entender las razones por las cuales nuestro filósofo de la ciencia va trasladando sus distintos focos de discusión o crítica. A common element in studies of Paul Karl Feyerabend is the distinction between five periods in his work. John Preston sees a radical discontinuity between the early and late versions of Feyerabend’s thought. All of this contributes our having a fragmented and incomplete view of a thinker who continued to evolve until 1994, the year of his death. We aim to provide an explanation of his intellectual journey that shows the evident continuity and unity of his thought. We will discuss the various issues he addressed in the different periods of his life, but at the same time we will emphasize the unity or logical coherence among them. Our aim is to understand the reasons why the philosopher of science changed his distinct foci of discussion and criticism. (shrink)

Convincing disputes about explanatory reductionism in the philosophy of biology require a clear and precise understanding of what a reductive explanation in biology is. The central aim of this book is to provide such an account by revealing the features that determine the reductive character of a biological explanation. Chapters I-IV provide the ground, on which I can then, in Chapter V, develop my own account of explanatory reduction in biology: Chapter I reveals the meta-philosophical assumptions that underlie my analysis (...) of reduction, Chapter II introduces the previous debate about reduction in the philosophy of biology by pointing out the most crucial lessons one should learn from this debate, Chapter III critically discusses the two perspectives on explanatory reduction that have been proposed in the philosophy of biology so far, and Chapter IV clarifies in what ways the issue of reduction is entangled with the issue of explanation. In Chapter V I present my own account of explanatory reduction. My main claim is that reductive explanations in the biological sciences possess three main characteristics: they explain the behavior of a biological system S, first, exclusively in terms of factors that are located on a lower level of organization than S, second, by focusing on factors that are internal to S , and third, by describing the genuine parts of S only as “parts in isolation”. This account is ontic because it traces the reductivity of an explanation back to certain relations that exist in the world. (shrink)

Traditional logical empiricist and more recent historicist positions on the logic of discovery are briefly reviewed and both are found wanting. None have examined the historical detail now available from recent research on Darwin, from which there is evidence for gradual transition in descriptive and explanatory concepts. This episode also shows that revolutionary research can be directed by borrowed metascientific objectives and heuristics from other disciplines. Darwin's own revolutionary research took place within an ontological context borrowed from non evolutionary predecessors (...) with methodological objectives borrowed from and justified by their success in Newton's physics. The logic of discovery is not a special form of inference from observation to theory, but rather a theory of the rationality of research, including principles bearing upon the rational choice of problems, or epistemic objectives, and heuristic, or means to solving the problems. Such choices can be justified only locally in the context of a relatively stable background ontology and substantive epistemology, not globally for all science. (shrink)

Foundationalist theories of justification for science were undermined by the theory-ladeness thesis, which has affinities with coherentist epistemologies. A challenge for defenders of coherentist theories of scientific justification is to specify coherence relations relevant to science and to show how these relations make the truth of their bearers likely. Coherence relations include characteristics that pick out better explanations in the implementation of abductive arguments. Empiricist philosophers have attacked abductive reasoning by claiming that explanatory virtues are pragmatic, having no implications regarding (...) truth. However, empiricist's basic beliefs are subject to the same challenges facing abduction, both of which can be met by citing causally coherent etiologies, which are commonplace in biological explanations, and by demonstrating the relevance of causal coherence to truth. (shrink)

In this paper, three theories of progress and the aim of science are discussed: the theory of progress as increasing explanatory power, advocated by Popper in The logic of scientific discovery ; the theory of progress as approximation to the truth, introduced by Popper in Conjectures and refutations ; the theory of progress as a steady increase of competing alternatives, which Feyerabend put forward in the essay “Reply to criticism. Comments on Smart, Sellars and Putnam” and defended as late as (...) the last edition of Against method. It is argued that, contrary to what Feyerabend scholars have predominantly assumed, Feyerabend's changing attitude towards falsificationism—which he often advocated at the beginning of his career, and vociferously attacked in the 1970s and 1980s—must be explained by taking into account not only Feyerabend's very peculiar view of the aim of science, but also Popper's changing account of progress. (shrink)

Up to the introduction of the term and concept of incommensurability by T. S. Kuhn and P. K. Feyerabend in the early 1960s, scientific texts were supposed to pose no problem as regards their translation, unlike literature, which was thought very difficult to translate. After the introduction of the term, translation of scientific language became equally problematic because, due to conceptual and perceptual incommensurability, there was no common observation basis to ground linguistic equivalences between languages of incommensurable paradigms. This article (...) highlights the presuppositions that link incommensurability to dramatic consequences (impossibility of communication, translation, and comparative evaluation of paradigms) and tries to sketch an alternative way of understanding incommensurability and translation drawing on Kuhn’s work. From this perspective, translation is not an all-or-nothing affair for either science or literature and becomes a problem to be solved for each particular set of circumstances. (shrink)

Es wird ausgegangen von den in den empirischen Wissenschaften vorkommenden Satzarten. Die Abhängigkeit der Kennzeichnungen "vollständig" bzw. "hinreichend verifiziert" von den Kriterien der benützten Überprüfungsverfahren wird untersucht. Die irrigen Voraussetzungen extremer Verallgemeinerungen, wie der "Verifikations-these" Wittgensteins und der "asymmetrischen Falsifikationstheorie" Poppers, werden aufgezeigt. Die methodologische Symmetrie von Verifikation und Falsifikation wird durch den Hinweis auf die gleicherweise unerläßliche Bedeutung der induktiven Schritte und des kontrollierenden Aufsuchens von Unverträglichkeiten für den wissenschaftlichen Fortschritt begründet. Unter Berücksichtigung dieser Kriterien werden empirische Allsätze als (...) die Beschreibung der realen Ordnung empirischer Phänomene gedeutet. (shrink)

Kitcher's unification theory of explanation seems to suggest that only the most reductive accounts can legitimately be termed explanatory. This is not what we find in actual scientific practice. In this paper, I attempt to reconcile these ideas. I claim that Kitcher's theory picks out ideal explanations, but that our term explanation is used to cover other accounts that have a certain relationship with the ideal accounts. At times, versions and portions of ideal explanations can also be considered explanatory.

The main purpose of this paper is to investigate various notions of empirical equivalence in relation to the two main arguments for realism in the philosophy of science, namely the no-miracles argument and the indispensability argument. According to realism, one should believe in the existence of the theoretical entities postulated by empirically adequate theories. According to the no-miracles argument, one should do so because truth is the the best explanation of empirical adequacy. According to the indispensability argument, one should do (...) so because the theoretical terms employed in the formulation of an empirically adequate theory are practically indispensable for the formulation of its empirical content. The no-miracles argument might be refuted if one can establish an underdetermination thesis to the effect that every theory has empirically equivalent rivals that are incompatible with each other. Insofar as truth cannot explain the empirical adequacy of two incompatible theories, there is an obvious conflict between the underdetermination thesis and the no-miracles argument. I show that, under certain assumptions, some but not all notions of empirical equivalence support the underdetermination thesis. The indispensability argument might be refuted if one can establish a dispensability thesis to the effect that, for any theory with a practical formulation, there is an empirically equivalent theory with a practical formulation in purely empirical terms. I show that some but not all notions of empirical equivalence support this thesis. (shrink)

Philosophy of science and history of science both have a significant relation to science itself; but what is their relation to each other? That question has been a focal point of philosophical and historical work throughout the second half of this century. An analysis and review of the progress made in dealing with this question, and especially that made in philosophy, is the focus of this thesis. Chapter one concerns logical positivist and empiricist approaches to philosophy of science, and the (...) significance of the criticisms levelled at them by analytic epistemologists such as Willard Quine and 'historicist' philosophers, especially Thomas Kuhn. Chapter two details the attempts by Kuhn and Lakatos to integrate these historicist criticisms with historically oriented philosophy of science, in their separate attempts at providing rational explanations of historical developments. Kuhn's latest work seeks to mend fences with philosophy, but his efforts remain too closely tied to the epistemological approaches strongly criticized in his earlier work. Lakatos' treatment of history is much more subtle than most have understood it to be, but the conception of scientific rationality that arises out of it is transformed into an abstract cultural product, more reminiscent of Hegel's geist than of individual human rationality. Chapters three and four discuss the recommendations of Lakatos and Laudan to historians with regard to historiography, and the actual historiographies and philosophy of history of practicing historians and historians of science. The philosophers' contributions indicate little concern for the historians' own methods, materials, and purposes; and the historians' writings present methodologies for history of science that are independent of the normative demarcations of philosophy of science, pace Lakatos and Laudan. Chapter five develops a philosophical position that fosters a more productive engagement between philosophy and history of science, a 'methodological historicism' that embraces the possibility of an important role for social and political factors in a philosophical study of scientific development. The epistemological relativism that might accompany such a historicist position need not be the radical epistemological anarchism of Feyerabend, though it will allow for a significant underdetermination of scientific development by reason nonetheless. (shrink)

An elementary algebra identifies conceptual and corresponding applicational limitations in John Kemeny and Paul Oppenheim’s (K-O) 1956 model of theoretical reduction in the sciences. The K-O model was once widely accepted, at least in spirit, but seems afterward to have been discredited, or in any event superceeded. Today, the K-O reduction model is seldom mentioned, except to clarify when a reduction in the Kemeny-Oppenheim sense is not intended. The present essay takes a fresh look at the basic mathematics of K-O (...) comparative vocabulary theoretical term reductions, from historical and philosophical standpoints, as a contribution to the history of the philosophy of science. The K-O theoretical reduction model qualifies a theory replacement as a successful reduction when preconditions of explanatory adequacy and comparable systematicization are met, and there occur fewer numbers of theoretical terms identified as replicable syntax types in the most economical statement of a theory’s putative propositional truths, as compared with the theoretical term count for the theory it replaces. The challenge to the historical model developed here, to help explain its scope and limitations, involves the potential for equivocal theoretical meanings of multiple theoretical term tokens of the same syntactical type. (shrink)

n this article the author develops a critique of reductionism in biological sciences from three different points of view. The first is related to the problem of reduction in the context of scientific theories. More specifically, reduction deals with a special form of intertheoretic relationship between molecular biology and the rest of biology. The second meaning of reductionism has to do with the significance of its genetic outfit for the ontogeny of an organism, i.e. its development from zygote to its (...) final or adult structure and function. Third, closely related to this more biological topic are questions about the anthropological consequences of the application of reductionistic methodologies for the explanation and evaluation of human behaviour. (shrink)

In scientific explanations, the explanans theory is sometimes incommensurable with the explanandum empirical data. How is this possible, especially when the explanation is deductive in nature? This paper attempts to solve the puzzle without relying on any particular theory of reference. For us, it is rather obvious that the geometric idea of projection plays a key role in Keplers explanation of Tycho Brahes empirical data. We discover that a similar mechanism operates in theoretic explanations in general. In short, all theoretic (...) explanations are projective explanations. If so, there should be no logical reason why explanans theories cannot be incommensurable with explanandum data. For illustration, we analyse Einsteins explanation of the results of the Michelson–Morley experiment in some detail. (shrink)

Contrary to Sankey’s central assumption, incommensurability does not imply incomparability of content, nor threaten scientific realism by challenging the rationality of theory comparison. Moreover, Sankey equivocates between reference to specific entities by statements used to test theories and reference to kinds by theories themselves. This distinction helps identify and characterize the genuine threat that incommensurability poses to realism, which is ontological discontinuity as evidenced in the historical record: Successive theories reclassify objects into mutually exclusive sets of kinds to which they (...) refer. That is why claiming that scientific progress is an increasingly better approximation to truth is difficult to justify. Similarly, Sankey’s attack on neo-Kantian antirealist positions is based on his misunderstanding of some of the central terms of those positions, making most of his attack on them ineffectual, including his diagnosis of their incoherence. We conclude by reiterating our conviction that in this debate meta-incommensurability plays an important role.Keywords: Scientific realism; Incommensurability; Meta-incommensurability; Thomas Kuhn; Paul Feyerabend; Howard Sankey. (shrink)

The paper discusses some aspects of the relationship between Feyerabend and Kuhn. First, some biographical remarks concerning their connections are made. Second, four characteristics of Feyerabend and Kuhn's concept of incommensurability are discussed. Third, Feyerabend's general criticism of Kuhn's Structure of Scientific Revolutions is reconstructed. Forth and more specifically, Feyerabend's criticism of Kuhn's evaluation of normal science is critically investigated. Finally, Feyerabend's re-evaluation of Kuhn's philosophy towards the end of his life is presented.

ABSTRACT What do we disagree about when we disagree about logic? On the face of it, classical and nonclassical logicians disagree about the laws of logic and the nature of logical properties. Yet, sometimes the parties are accused of talking past each other. The worry is that if the parties to the dispute do not mean the same thing with ‘if’, ‘or’, and ‘not’, they fail to have genuine disagreement about the laws in question. After the work of Quine, this (...) objection against genuine disagreement about logic has been called the meaning-variance thesis. We argue that the meaning-variance thesis can be endorsed without blocking genuine disagreement. In fact, even the type of revisionism and nonapriorism championed by Quine turns out to be compatible with meaning-variance. (shrink)

This paper argues that the normative character of our unreflective situated behaviour is not factual. We highlight a problematic assumption shared by the two most influential trends in contemporary philosophy of cognitive science, reductionism and enactivism. Our intentional, normative explanations are referential, descriptive or factual. Underneath this assumption lies the idea that only facts can make true or false our attributions of cognitive, mental and agential abilities. We will argue against this view by describing the main features and problems of (...) reductionism and enactivism and then we will offer two arguments against this shared factualist assumption: (1) normative vocabulary is ineliminable if we want a complete explanation of our situated practices; and (2) the factualist assumption is a species of the is-ought fallacy. Finally, we will claim that a folk psychological explanation of our normative practices is fully compatible with ontological naturalism when such descriptivist or factualist assumption is rejected. (shrink)

Attempting to compare scientific theories requires a philosophical model of meaning. Yet different scientific theories have at times—particularly in early chemistry—pre-supposed disparate theories of meaning. When two theories of meaning are incommensurable, we must say that the scientific theories that rely upon them are meta-incommensurable. Meta- incommensurability is a more profound sceptical threat to science since, unlike first-order incommensurability, it implies complete incomparability.

This inaugural handbook documents the distinctive research field that utilizes history and philosophy in investigation of theoretical, curricular and pedagogical issues in the teaching of science and mathematics. It is contributed to by 130 researchers from 30 countries; it provides a logically structured, fully referenced guide to the ways in which science and mathematics education is, informed by the history and philosophy of these disciplines, as well as by the philosophy of education more generally. The first handbook to cover the (...) field, it lays down a much-needed marker of progress to date and provides a platform for informed and coherent future analysis and research of the subject. -/- The publication comes at a time of heightened worldwide concern over the standard of science and mathematics education, attended by fierce debate over how best to reform curricula and enliven student engagement in the subjects There is a growing recognition among educators and policy makers that the learning of science must dovetail with learning about science; this handbook is uniquely positioned as a locus for the discussion. -/- The handbook features sections on pedagogical, theoretical, national, and biographical research, setting the literature of each tradition in its historical context. Each chapter engages in an assessment of the strengths and weakness of the research addressed, and suggests potentially fruitful avenues of future research. A key element of the handbook’s broader analytical framework is its identification and examination of unnoticed philosophical assumptions in science and mathematics research. It reminds readers at a crucial juncture that there has been a long and rich tradition of historical and philosophical engagements with science and mathematics teaching, and that lessons can be learnt from these engagements for the resolution of current theoretical, curricular and pedagogical questions that face teachers and administrators. (shrink)

This paper proposes a classification of the intertheoretic relations in physics by bringing out the conditions for a relation of reduction which is eliminative, so that a theory reduced in terms of reductionism is superfluous in principle, and by distinguishing such a relation from another one based on comparison, which will be called neighbourhood of theories; the latter is a neighbouring relation between theories and is not able to support claims of eliminative reductionism. In the first part, it will be (...) argued that this differentiation between neighbourhood and eliminative reduction permits an adequate classification of the intertheoretic relations in physics. By means of this differentiation, the second part discusses reductionism and shows that there are indeed some historical examples of reduction in the aforementioned sense, but that modern physical theories are typically only neighbouring. (shrink)

Work on analogy has been done from a number of disciplinary perspectives throughout the history of Western thought. This work is a multidisciplinary guide to theorizing about analogy. It contains 1,406 references, primarily to journal articles and monographs, and primarily to English language material. classical through to contemporary sources are included. The work is classified into eight different sections (with a number of subsections). A brief introduction to each section is provided. Keywords and key expressions of importance to research on (...) analogy are discussed in the introductory material. Electronic resources for conducting research on analogy are listed as well. (shrink)

This chapter contains sections titled: Highlights of Past Literature Current Work Future Work.

This paper attempts to delineate a kind of realism, which incorporates some anti-realistic insights regarding the perspective, situated, and historical character of our forms of knowing and being in the world, and which resonates with the basic tenets of Christian theism. The first part of the paper analyzes the challenges anti-realism poses to Christian theism, particularly regarding the role, which the doctrine of creation played in securing the correspondence theory of truth as well as the fundamental experience of God as (...) the foundation of order and meaning. Using Heidegger’s hermeneutics in the second part, it is shown that epistemic pluralism can be made compatible with realism. Given that this form of hermeneutic realism still has problems with integrating the transcendence of God, as well as his/ her presence and action in the “world,” the notion of continuous co-creation as the basis for a pluralist realism that is amenable to Christian theism is explored in the final part. (shrink)