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  1. Intervention, Causal Reasoning, and the Neurobiology of Mental Disorders: Pharmacological Drugs as Experimental Instruments.Jonathan Y. Tsou - 2012 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 43 (2):542-551.
    In psychiatry, pharmacological drugs play an important experimental role in attempts to identify the neurobiological causes of mental disorders. Besides being developed in applied contexts as potential treatments for patients with mental disorders, pharmacological drugs play a crucial role in research contexts as experimental instruments that facilitate the formulation and revision of neurobiological theories of psychopathology. This paper examines the various epistemic functions that pharmacological drugs serve in the discovery, refinement, testing, and elaboration of neurobiological theories of mental disorders. I (...)
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  • What Does History Matter to Philosophy of Science? The Concept of Replication and the Methodology of Experiments.Jutta Schickore - 2011 - Journal of the Philosophy of History 5 (3):513-532.
    Scientists and philosophers generally agree that the replication of experiments is a key ingredient of good and successful scientific practice. “One-offs“ are not significant; experiments must be replicable to be considered valid and important. But the term “replication“ has been used in a number of ways, and it is therefore quite difficult to appraise the meaning and significance of replications. I consider how history may help - and has helped - with this task. I propose that: 1) Studies of past (...)
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  • Testing universal gravitation in the laboratory, or the significance of research on the mean density of the earth and big G, 1798–1898: changing pursuits and long-term methodological–experimental continuity.Steffen Ducheyne - 2011 - Archive for History of Exact Sciences 65 (2):181-227.
    This article seeks to provide a historically well-informed analysis of an important post-Newtonian area of research in experimental physics between 1798 and 1898, namely the determination of the mean density of the earth and, by the end of the nineteenth century, the gravitational constant. Traditionally, research on these matters is seen as a case of “puzzle solving.” In this article, the author shows that such focus does not do justice to the evidential significance of eighteenth- and nineteenth-century experimental research on (...)
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  • Robustness, discordance, and relevance.Jacob Stegenga - 2009 - Philosophy of Science 76 (5):650-661.
    Robustness is a common platitude: hypotheses are better supported with evidence generated by multiple techniques that rely on different background assumptions. Robustness has been put to numerous epistemic tasks, including the demarcation of artifacts from real entities, countering the “experimenter’s regress,” and resolving evidential discordance. Despite the frequency of appeals to robustness, the notion itself has received scant critique. Arguments based on robustness can give incorrect conclusions. More worrying is that although robustness may be valuable in ideal evidential circumstances (i.e., (...)
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  • The epistemology of experiment. [REVIEW]Allan Franklin - 1984 - British Journal for the Philosophy of Science 35 (4):381-390.
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  • Robust evidence and secure evidence claims.Kent W. Staley - 2004 - Philosophy of Science 71 (4):467-488.
    Many philosophers have claimed that evidence for a theory is better when multiple independent tests yield the same result, i.e., when experimental results are robust. Little has been said about the grounds on which such a claim rests, however. The present essay presents an analysis of the evidential value of robustness that rests on the fallibility of assumptions about the reliability of testing procedures and a distinction between the strength of evidence and the security of an evidence claim. Robustness can (...)
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  • Popper, prior probabilities, and inductive inference.Colin Howson - 1987 - British Journal for the Philosophy of Science 38 (2):207-224.
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  • Philosophy of Psychiatry.Jonathan Y. Tsou - 2021 - Cambridge: Cambridge University Press.
    Jonathan Y. Tsou examines and defends positions on central issues in philosophy of psychiatry. The positions defended assume a naturalistic and realist perspective and are framed against skeptical perspectives on biological psychiatry. Issues addressed include the reality of mental disorders; mechanistic and disease explanations of abnormal behavior; definitions of mental disorder; natural and artificial kinds in psychiatry; biological essentialism and the projectability of psychiatric categories; looping effects and the stability of mental disorders; psychiatric classification; and the validity of the DSM's (...)
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  • Forty Years after Laboratory Life.Joyce C. Havstad - 2020 - Philosophy, Theory, and Practice in Biology 12.
    There is an ongoing and robust tradition of science and technology studies scholars conducting ethnographic laboratory studies. These laboratory studies—like all ethnographies—are each conducted at a particular time, are situated in a particular place, and are about a particular culture. Presumably, this contextual specificity means that such ethnographies have limited applicability beyond the narrow slice of time, place, and culture that they each subject to examination. But we do not always or even often treat them that way. It is beyond (...)
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  • The variety of evidence thesis and its independence of degrees of independence.Jürgen Landes - 2020 - Synthese 198 (11):1-31.
    The intuitive Variety of Evidence Thesis states that, ceteris paribus, more varied evidence for a hypothesis confirms it more strongly than less varied evidence. Recent Bayesian analyses have raised serious doubts in its validity. Claveau suggests the existence of a novel type of counter-example to this thesis: a gradual increase in source independence can lead to a decrease in hypothesis confirmation. I show that Claveau’s measure of gradual source independence suffers from two unsuspected types of inconsistencies. I hence put forward (...)
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  • Pharmacological Interventions and the Neurobiological Basis of Mental Disorders.Jonathan Y. Tsou - 2017 - In Opris Ioan & F. Casanova Manuel (eds.), The Physics of the Mind and Brain Disorders: Integrated Neural Circuits Supporting the Emergence of Mind. Springer. pp. 613-628.
    In psychiatry, pharmacological research has played a crucial role in the formulation, revision, and refinement of neurobiological theories of psychopathology. Besides being utilized as potential treatments for various mental disorders, pharmacological drugs play an important epistemic role as experimental instruments that help scientists uncover the neurobiological underpinnings of mental disorders (Tsou, 2012). Interventions with psychiatric patients using pharmacological drugs provide researchers with information about the neurobiological causes of mental disorders that cannot be obtained in other ways. This important source of (...)
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  • It Probably is a Valid Experimental Result: a Bayesian Approach to the Epistemology of Experiment.Allan Franklin - 1988 - Studies in History and Philosophy of Science Part A 19 (4):419.
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  • Towards a Typology of Experimental Errors: an Epistemological View.Giora Hon - 1989 - Studies in History and Philosophy of Science Part A 20 (4):469.
    This paper is concerned with the problem of experimental error. The prevalent view that experimental errors can be dismissed as a tiresome but trivial blemish on the method of experimentation is criticized. It is stressed that the occurrence of errors in experiments constitutes a permanent feature of the attempt to test theories in the physical world, and this feature deserves proper attention. It is suggested that a classification of types of experimental error may be useful as a heuristic device in (...)
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  • Tools for Evaluating the Consequences of Prior Knowledge, but no Experiments. On the Role of Computer Simulations in Science.Eckhart Arnold - manuscript
    There is an ongoing debate on whether or to what degree computer simulations can be likened to experiments. Many philosophers are sceptical whether a strict separation between the two categories is possible and deny that the materiality of experiments makes a difference (Morrison 2009, Parker 2009, Winsberg 2010). Some also like to describe computer simulations as a “third way” between experimental and theoretical research (Rohrlich 1990, Axelrod 2003, Kueppers/Lenhard 2005). In this article I defend the view that computer simulations are (...)
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  • (4 other versions)An empiricist defence of singular causes.Nancy Cartwright - 2000 - Royal Institute of Philosophy Supplement 46:47-58.
    Empiricism has traditionally been concerned with two questions: What is the source of our concepts and ideas? and How should claims to empirical knowledge be judged? The empiricist answer to the first question is ‘From observation or experience.’ The concern in the second question is not to ground science in pure observation or in direct experience, but rather to ensure that claims to scientific knowledge are judged against the natural phenomena themselves. Questions about nature must be settled by nature — (...)
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  • Natural Kinds, Psychiatric Classification and the History of the DSM.Jonathan Y. Tsou - 2016 - History of Psychiatry 27 (4):406-424.
    This paper addresses philosophical issues concerning whether mental disorders are natural kinds and how the DSM should classify mental disorders. I argue that some mental disorders (e.g., schizophrenia, depression) are natural kinds in the sense that they are natural classes constituted by a set of stable biological mechanisms. I subsequently argue that a theoretical and causal approach to classification would provide a superior method for classifying natural kinds than the purely descriptive approach adopted by the DSM since DSM-III. My argument (...)
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  • Robustness and reality.Markus I. Eronen - 2015 - Synthese 192 (12):3961-3977.
    Robustness is often presented as a guideline for distinguishing the true or real from mere appearances or artifacts. Most of recent discussions of robustness have focused on the kind of derivational robustness analysis introduced by Levins, while the related but distinct idea of robustness as multiple accessibility, defended by Wimsatt, has received less attention. In this paper, I argue that the latter kind of robustness, when properly understood, can provide justification for ontological commitments. The idea is that we are justified (...)
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  • Experimenter’s regress argument, empiricism, and the calibration of the large hadron collider.Slobodan Perovic - 2017 - Synthese 194 (2):313-332.
    H. Collins has challenged the empiricist understanding of experimentation by identifying what he thinks constitutes the experimenter’s regress: an instrument is deemed good because it produces good results, and vice versa. The calibration of an instrument cannot alone validate the results: the regressive circling is broken by an agreement essentially external to experimental procedures. In response, A. Franklin has argued that calibration is a key reasonable strategy physicists use to validate production of results independently of their interpretation. The physicists’ arguments (...)
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  • The Methodological Strategy of Robustness in the Context of Experimental WIMP Research.Robert Hudson - 2009 - Foundations of Physics 39 (2):174-193.
    According to the methodological principle called ‘robustness’, empirical evidence is more reliable when it is generated using multiple, independent (experimental) routes that converge on the same result. As it happens, robustness as a methodological strategy is quite popular amongst philosophers. However, despite its popularity, my goal here is to criticize the value of this principle on historical grounds. My historical reasons take into consideration some recent history of astroparticle physics concerning the search for WIMPs (weakly interacting massive particles), one of (...)
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  • Robustness, Reliability, and Overdetermination (1981).William C. Wimsatt - 2012 - In Lena Soler (ed.), Characterizing the robustness of science: after the practice turn in philosophy of science. New York: Springer Verlag. pp. 61-78.
    The use of multiple means of determination to “triangulate” on the existence and character of a common phenomenon, object, or result has had a long tradition in science but has seldom been a matter of primary focus. As with many traditions, it is traceable to Aristotle, who valued having multiple explanations of a phenomenon, and it may also be involved in his distinction between special objects of sense and common sensibles. It is implicit though not emphasized in the distinction between (...)
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  • Variety of Evidence.Jürgen Landes - 2020 - Erkenntnis 85 (1):183-223.
    Varied evidence confirms more strongly than less varied evidence, ceteris paribus. This epistemological Variety of Evidence Thesis enjoys widespread intuitive support. We put forward a novel explication of one notion of varied evidence and the Variety of Evidence Thesis within Bayesian models of scientific inference by appealing to measures of entropy. Our explication of the Variety of Evidence Thesis holds in many of our models which also pronounce on disconfirmatory and discordant evidence. We argue that our models pronounce rightly. Against (...)
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  • Two Senses of Experimental Robustness: Result Robustness and Procedure Robustness.Koray Karaca - 2022 - British Journal for the Philosophy of Science 73 (1):279-298.
    In the philosophical literature concerning scientific experimentation, the notion of robustness has been solely discussed in relation to experimental results. In this paper, I propose a novel sense of experimental robustness that applies to experimental procedures. I call the foregoing sense of robustness procedure robustness and characterize it as the capacity of an experimental procedure to maintain its intended function invariant during the experimental process despite possible variations in its inputs. I argue that PR is a precondition for what I (...)
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  • Robustness, evidence, and uncertainty: an exploration of policy applications of robustness analysis.Nicolas Wüthrich - unknown
    Policy-makers face an uncertain world. One way of getting a handle on decision-making in such an environment is to rely on evidence. Despite the recent increase in post-fact figures in politics, evidence-based policymaking takes centre stage in policy-setting institutions. Often, however, policy-makers face large volumes of evidence from different sources. Robustness analysis can, prima facie, handle this evidential diversity. Roughly, a hypothesis is supported by robust evidence if the different evidential sources are in agreement. In this thesis, I strengthen the (...)
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  • Using Multiple Means of Determination.Jutta Schickore & Klodian Coko - 2013 - International Studies in the Philosophy of Science 27 (3):295-313.
    This article examines a metaphilosophical issue, namely existing disagreements in philosophy of science about the significance of using multiple means of determination in scientific practice. We argue that this disagreement can, in part, be resolved by separating different questions that can be asked about the use of multiple means of determination, including the following: what can be concluded from the convergence of data or the convergence of claims about phenomena? Are the conclusions drawn from the convergence of data and of (...)
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  • The resolution of discordant results.Allan Franklin - 1995 - Perspectives on Science 3 (3):346-420.
    Experiments often disagree. How then can scientific knowledge be based on experimental evidence? In this paper I will examine four episodes from the history of recent physics: the suggestion of a Fifth Force, a modification of Newton’s law of gravitation; early attempts to detect gravitational radiation ; the claim that a 17-keV neutrino exists; and experiments on atomic-parity violation and on the scattering of polarized electrons and their relation to the Weinberg-Salam unified theory of electroweak interactions. In each of these (...)
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  • The Elusive Basis of Inferential Robustness.James Justus - 2012 - Philosophy of Science 79 (5):795-807.
    Robustness concepts are often invoked to manage two obstacles confronting models of ecological systems: complexity and uncertainty. The intuitive idea is that any result derived from many idealized but credible models is thereby made more reliable or is better confirmed. An appropriate basis for this inference has proven elusive. Here, several representations of robustness analysis are vetted, paying particular attention to complex models of ecosystems and the global climate. The claim that robustness is itself confirmatory because robustness analysis employs a (...)
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  • The role of replication in psychological science.Samuel C. Fletcher - 2021 - European Journal for Philosophy of Science 11 (1):1-19.
    The replication or reproducibility crisis in psychological science has renewed attention to philosophical aspects of its methodology. I provide herein a new, functional account of the role of replication in a scientific discipline: to undercut the underdetermination of scientific hypotheses from data, typically by hypotheses that connect data with phenomena. These include hypotheses that concern sampling error, experimental control, and operationalization. How a scientific hypothesis could be underdetermined in one of these ways depends on a scientific discipline’s epistemic goals, theoretical (...)
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  • “It might be this, it should be that…” uncertainty and doubt in day-to-day research practice.Jutta Schickore & Nora Hangel - 2019 - European Journal for Philosophy of Science 9 (2):1-21.
    This paper examines how scientists conceptualize their research methodologies. Do scientists raise concerns about vague criteria and genuine uncertainties in experimental practice? If so, what sorts of issues do they identify as problematic? Do scientists acknowledge the presence of value judgments in scientific research, and do they reflect on the relation between epistemic and non-epistemic criteria for decisionmaking? We present findings from an analysis of qualitative interviews with 63 scientific researchers who talk about their views on good research practice. We (...)
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  • When a Crisis Becomes an Opportunity: The Role of Replications in Making Better Theories.Jane Suilin Lavelle - 2022 - British Journal for the Philosophy of Science 73 (4):965-986.
    While it is widely acknowledged that psychology is in the throes of a replication ‘crisis’, relatively little attention has been paid to the role theory plays in our evaluation of replications as ‘failed’ or ‘successful’. This paper applies well-known arguments in philosophy of science about the interplay between theory and experiment to a contemporary case study of infants’ understanding of false belief (Onishi and Baillargeon [2005]), and attempts to replicate it. It argues that the lack of consensus about over-arching theories (...)
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  • Variety of evidence and the elimination of hypotheses.Jürgen Landes - 2020 - European Journal for Philosophy of Science 10 (2):1-17.
    Varied evidence for a hypothesis confirms it more strongly than less varied evidence, ceteris paribus. This epistemological Variety of Evidence Thesis enjoys long-standing widespread intuitive support. Recent literature has raised serious doubts that the correlational approach of explicating the thesis can vindicate it. By contrast, the eliminative approach due to Horwich vindicates the Variety of Evidence Thesis but only within a relatively narrow domain. I investigate the prospects of extending the eliminative approach to a larger domain by considering a larger (...)
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  • Homepage Eckhart Arnold.Eckhart Arnold (ed.) - 2001 - Munich: Preprint.
    This is my personal homepage. Find my philosophical papers under "Philosophy".
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  • Experimental Skills and Experiment Appraisal.Xiang Chen - 1994 - In Peter Achinstein & Laura J. Snyder (eds.), Scientific methods: conceptual and historical problems. Malabar, Fla.: Krieger Pub. Co.. pp. 45--66.
    Traditional philosophy of science believes that scientists can achieve agreement on every experimental result provided it can be replicated in an appropriate way, that is, reproducible with the same experimen­tal arrangement and procedure. By analyzing the role of skills in experiment appraisal, I explain why in fact scientists do not always have consensus on experimental results despite their replication attempts. Based on a detailed analysis of a historical case, I argue that experiment replications inevitably involve a processor skill­ transference, which (...)
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  • Bayesianism and diverse evidence.Andrew Wayne - 1995 - Philosophy of Science 62 (1):111-121.
    A common methodological adage holds that diverse evidence better confirms a hypothesis than does the same amount of similar evidence. Proponents of Bayesian approaches to scientific reasoning such as Horwich, Howson and Urbach, and Earman claim to offer both a precise rendering of this maxim in probabilistic terms and an explanation of why the maxim should be part of the methodological canon of good science. This paper contends that these claims are mistaken and that, at best, Bayesian accounts of diverse (...)
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  • Explaining simulated phenomena. A defense of the epistemic power of computer simulations.Juan M. Durán - 2013 - Dissertation, University of Stuttgart
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  • Evidential diversity and premise probability in young children's inductive judgment.Yafen Lo, Ashley Sides, Joseph Rozelle & Daniel Osherson - 2002 - Cognitive Science 26 (2):181-206.
    A familiar adage in the philosophy of science is that general hypotheses are better supported by varied evidence than by uniform evidence. Several studies suggest that young children do not respect this principle, and thus suffer from a defect in their inductive methodology. We argue that the diversity principle does not have the normative status that psychologists attribute to it, and should be replaced by a simple rule of probability. We then report experiments designed to detect conformity to the latter (...)
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  • Bayesian conditionalization and probability kinematics.Colin Howson & Allan Franklin - 1994 - British Journal for the Philosophy of Science 45 (2):451-466.
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  • Variation and the accuracy of predictions.Michael Kruse - 1997 - British Journal for the Philosophy of Science 48 (2):181-193.
    I present a justification for the intution that more-varied data are more valuable than the same number of less-varied data by showing that the more-varied data help to improve the accuracy of our predictions.
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  • Stronger evidence.Peter Achinstein - 1994 - Philosophy of Science 61 (3):329-350.
    According to a standard account of evidence, one piece of information is stronger evidence for an hypothesis than is another iff the probability of the hypothesis on the one is greater than it is on the other. This condition, I argue, is neither necessary nor sufficient because various factors can strengthen the evidence for an hypothesis without increasing (and even decreasing) its probability. Contrary to what probabilists claim, I show that this obtains even if a probability function can take these (...)
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  • "When" do Scientists Prefer to Vary their Experiments?H. M. Collins - 1984 - Studies in History and Philosophy of Science Part A 15 (2):169.
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  • Credentialing scientific claims.Frederick Suppe - 1993 - Perspectives on Science 1 (2):153-203.
    This article seeks rapprochement between the sociology of knowledge and philosophy of science by attempting to capture the best social constructionist insights within a strongly realistic philosophy of science. Key to doing so are separating the grounds for the individual scientist coming to know that P from those grounds for socially credentialing the claim that P within the relevant scientific subcommunity and showing how truth considerations can enter into the analysis of knowledge without interfering with social constructionist treatments of credentialing (...)
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  • Newton and Kepler, a Bayesian Approach.Allan Franklin - 1984 - Studies in History and Philosophy of Science Part A 16 (4):379.
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  • The Machine Speaks Falsely.Allan Franklin - 2010 - Spontaneous Generations 4 (1):71-84.
    How can one determine if an experimental apparatus is giving an incorrect result, if it is speaking falsely? An interesting example of this occurred in the experimental investigation, in the early twentieth century, of the energy spectrum of electrons emitted in β decay. Meitner and her collaborators (1911), using photographic detection, found that all the electrons emitted by a single radioactive element were monoenergetic. Chadwick (1914), on the other hand, using either an ionization chamber or a Geiger counter, found a (...)
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  • Economics and the laboratory: some philosophical and methodological problems facing experimental economics.Francesco Guala - 1999 - Dissertation, London School of Economics and Political Science
    Laboratory experimentation was once considered impossible or irrelevant in economics. Recently, however, economic science has gone through a real ‘laboratory revolution’, and experimental economics is now a most lively subfield of the discipline. The methodological advantages and disadvantages of controlled experimentation constitute the main subject of this thesis. After a survey of the literature on experiments in philosophy and economics, the problem of testing normative theories of rationality is tackled. This philosophical issue was at the centre of a famous controversy (...)
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  • H. Hertz: 'The electrostatic and electromagnetic properties of the cathode rays are either "nil" or very feeble.' A Case-study of an Experimental Error.Giora Hon - 1987 - Studies in History and Philosophy of Science Part A 18 (3):367.
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  • Varieties of Error and Varieties of Evidence in Scientific Inference.Barbara Osimani & Jürgen Landes - 2023 - British Journal for the Philosophy of Science 74 (1):117-170.
    According to the variety of evidence thesis items of evidence from independent lines of investigation are more confirmatory, ceteris paribus, than, for example, replications of analogous studies. This thesis is known to fail (Bovens and Hartmann; Claveau). However, the results obtained by Bovens and Hartmann only concern instruments whose evidence is either fully random or perfectly reliable; instead, for Claveau, unreliability is modelled as deterministic bias. In both cases, the unreliable instrument delivers totally irrelevant information. We present a model that (...)
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  • Can a theory-Laden observation test the theory?A. Franklin, M. Anderson, D. Brock, S. Coleman, J. Downing, A. Gruvander, J. Lilly, J. Neal, D. Peterson, M. Price, R. Rice, L. Smith, S. Speirer & D. Toering - 1989 - British Journal for the Philosophy of Science 40 (2):229-231.
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  • Experimental questions.Allan Franklin - 1993 - Perspectives on Science 1 (1):127-46.
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