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  1. ‘Genetic Coding’ Reconsidered: An Analysis of Actual Usage.Ulrich E. Stegmann - 2016 - British Journal for the Philosophy of Science 67 (3):707-730.
    This article reconsiders the theoretical role of the genetic code. By drawing on published and unpublished sources from the 1950s, I analyse how the code metaphor was actually employed by the scientists who first promoted its use. The analysis shows that the term ‘code’ picked out mechanism sketches, consisting of more or less detailed descriptions of ordinary molecular components, processes, and structural properties of the mechanism of protein synthesis. The sketches provided how-possibly explanations for the ordering of amino acids by (...)
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  • Recent Work in The Philosophy of Biology.Christopher J. Austin - 2017 - Analysis 77 (2):anx032.
    The biological sciences have always proven a fertile ground for philosophical analysis, one from which has grown a rich tradition stemming from Aristotle and flowering with Darwin. And although contemporary philosophy is increasingly becoming conceptually entwined with the study of the empirical sciences with the data of the latter now being regularly utilised in the establishment and defence of the frameworks of the former, a practice especially prominent in the philosophy of physics, the development of that tradition hasn’t received the (...)
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  • ‘Genetic Coding’ Reconsidered: An Analysis of Actual Usage.Ulrich E. Stegmann - 2016 - British Journal for the Philosophy of Science 67 (3):707-730.
    This article reconsiders the theoretical role of the genetic code. By drawing on published and unpublished sources from the 1950s, I analyse how the code metaphor was actually employed by the scientists who first promoted its use. The analysis shows that the term ‘code’ picked out mechanism sketches, consisting of more or less detailed descriptions of ordinary molecular components, processes, and structural properties of the mechanism of protein synthesis. The sketches provided how-possibly explanations for the ordering of amino acids by (...)
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  • Información biológica: ¿La teoría de la información ataca de nuevo?María Ferreira Ruiz - 2019 - Manuscrito 42 (1):169-209.
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  • Foundations of a Probabilistic Theory of Causal Strength.Jan Sprenger - 2018 - Philosophical Review 127 (3):371-398.
    This paper develops axiomatic foundations for a probabilistic-interventionist theory of causal strength. Transferring methods from Bayesian confirmation theory, I proceed in three steps: I develop a framework for defining and comparing measures of causal strength; I argue that no single measure can satisfy all natural constraints; I prove two representation theorems for popular measures of causal strength: Pearl's causal effect measure and Eells' difference measure. In other words, I demonstrate these two measures can be derived from a set of plausible (...)
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  • Discussion Note: Which Kind of Causal Specificity Matters Biologically?Marcel Weber - unknown
    Griffiths et al. have proposed a quantitative measure of causal specificity and used it to assess various attempts to single out genetic causes as being causally more specific than other cellular mechanisms, for example, alternative splicing. Focusing in particular on developmental processes, they have identified a number of important challenges for this project. In this discussion note, I would like to show how these challenges can be met.
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  • Reference, Truth, and Biological Kinds.Marcel Weber - 2014 - In: J. Dutant, D. Fassio and A. Meylan (Eds.) Liber Amicorum Pascal Engel.
    This paper examines causal theories of reference with respect to how plausible an account they give of non-physical natural kind terms such as ‘gene’ as well as of the truth of the associated theoretical claims. I first show that reference fixism for ‘gene’ fails. By this, I mean the claim that the reference of ‘gene’ was stable over longer historical periods, for example, since the classical period of transmission genetics. Second, I show that the theory of partial reference does not (...)
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  • Causal Control and Genetic Causation.Ulrich Stegmann - 2014 - Noûs 48 (3):450-465.
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  • Collaborative Explanation and Biological Mechanisms.Melinda Bonnie Fagan - 2015 - Studies in History and Philosophy of Science Part A 52:67-78.
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  • Epistemology of Causal Inference in Pharmacology.Jürgen Landes, Barbara Osimani & Roland Poellinger - 2018 - European Journal for Philosophy of Science 8 (1):3-49.
    Philosophical discussions on causal inference in medicine are stuck in dyadic camps, each defending one kind of evidence or method rather than another as best support for causal hypotheses. Whereas Evidence Based Medicine advocates the use of Randomised Controlled Trials and systematic reviews of RCTs as gold standard, philosophers of science emphasise the importance of mechanisms and their distinctive informational contribution to causal inference and assessment. Some have suggested the adoption of a pluralistic approach to causal inference, and an inductive (...)
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  • Variation of Information as a Measure of One-to-One Causal Specificity.Pierrick Bourrat - 2019 - European Journal for Philosophy of Science 9 (1):11.
    The interventionist account provides us with several notions permitting the qualification of causal relationships. In recent years, there has been a push toward formalizing these notions using information theory. In this paper, I discuss one of them, namely causal specificity. The notion of causal specificity is ambiguous as it can refer to at least two different concepts. After having presented these, I show that current attempts to formalize causal specificity in information theoretic terms have mostly focused on one of these (...)
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  • Causation in Biology: Stability, Specificity, and the Choice of Levels of Explanation.James Woodward - 2010 - Biology and Philosophy 25 (3):287-318.
    This paper attempts to elucidate three characteristics of causal relationships that are important in biological contexts. Stability has to do with whether a causal relationship continues to hold under changes in background conditions. Proportionality has to do with whether changes in the state of the cause “line up” in the right way with changes in the state of the effect and with whether the cause and effect are characterized in a way that contains irrelevant detail. Specificity is connected both to (...)
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  • Dissecting Developmental Biology.Karola Stotz & Paul Griffiths - 2015 - Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences 53:134-138.
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