Part I Introduction The specific problem adressed in this thesis is: what is the rational use of theory and experiment in the process of scientific discovery, in theory and in the practice of drug research for Parkinson’s disease? The thesis aims to answer the following specific questions: what is: 1) the structure of a theory?; 2) the process of scientific reasoning?; 3) the route between theory and experiment? In the first part I further discuss issues about rationality in science as (...) introduction to part II, and I present an overview of my case-study of neuropharmacology, for which I interviewed researchers from the Groningen Pharmacy Department, as an introduction to part III. Part II Discovery In this part I discuss three theoretical models of scientific discovery according to studies in the fields of Logic, Cognition, and Computation. In those fields the structure of a theory is respectively explicated as: a set of sentences; a set of associated memory chunks; and as a computer program that can generate the observed data. Rationality in discovery is characterized by: finding axioms that imply observation sentences; heuristic search for a hypothesis, as part of problem solving, by applying memory chunks and production rules that represent skill; and finding the shortest program that generates the data, respectively. I further argue that reasoning in discovery includes logical fallacies, which are neccesary to introduce new hypotheses. I also argue that, while human subjects often make errors in hypothesis evaluation tasks from a logical perspective, these evaluations are rational given a probabilistic interpretation. Part III Neuropharmacology In this last part I discusses my case-study and a model of discovery in a practice of drug research for Parkinson’s disease. I discuss the dopamine theory of Parkinson’s disease and model its structure as a qualitative differential equation. Then I discuss the use and reasons for particular experiments to both test a drug and explore the function of the brain. I describe different kinds of problems in drug research leading to a discovery. Based on that description I distinguish three kinds of reasoning tasks in discovery, inference to: the best explanation, the best prediction and the best intervention. I further demonstrate how a part of reasoning in neuropharmacology can be computationally modeled as qualitative reasoning, and aided by a computer supported discovery system. (shrink)

Selectionist evolutionary theory has often been faulted for not making novel predictions that are surprising, risky, and correct. I argue that it in fact exhibits the theoretical virtue of predictive capacity in addition to two other virtues: explanatory unification and model fitting. Two case studies show the predictive capacity of selectionist evolutionary theory: parallel evolutionary change in E. coli, and the origin of eukaryotic cells through endosymbiosis.

The main aim of this paper is to revisit the curve fitting problem using the reliability of inductive inference as a primary criterion for the ‘fittest' curve. Viewed from this perspective, it is argued that a crucial concern with the current framework for addressing the curve fitting problem is, on the one hand, the undue influence of the mathematical approximation perspective, and on the other, the insufficient attention paid to the statistical modeling aspects of the problem. Using goodness-of-fit as the (...) primary criterion for ‘best', the mathematical approximation perspective undermines the reliability of inference objective by giving rise to selection rules which pay insufficient attention to ‘accounting for the regularities in the data'. A more appropriate framework is offered by the error-statistical approach, where (i) statistical adequacy provides the criterion for assessing when a curve captures the regularities in the data adequately, and (ii) the relevant error probabilities can be used to assess the reliability of inductive inference. Broadly speaking, the fittest curve (statistically adequate) is not determined by the smallness if its residuals, tempered by simplicity or other pragmatic criteria, but by the nonsystematic (e.g. white noise) nature of its residuals. The advocated error-statistical arguments are illustrated by comparing the Kepler and Ptolemaic models on empirical grounds. ‡I am grateful to Deborah Mayo and Clark Glymour for many valuable suggestions and comments on an earlier draft of the paper; estimating the Ptolemaic model was the result of Glymour's prompting and encouragement. †To contact the author, please write to: Department of Economics, Virginia Tech 3019 Pamplin Hall (0316), Blacksburg, VA 24061; e-mail: [email protected]. (shrink)

This paper describes the corner-stones of a means-ends approach to the philosophy of inductive inference. I begin with a fallibilist ideal of convergence to the truth in the long run, or in the 'limit of inquiry'. I determine which methods are optimal for attaining additional epistemic aims (notably fast and steady convergence to the truth). Means-ends vindications of (a version of) Occam's Razor and the natural generalizations in a Goodmanian Riddle of Induction illustrate the power of this approach. The paper (...) establishes a hierarchy of means-ends notions of empirical success, and discusses a number of issues, results and applications of means-ends epistemology. (shrink)

R. Laudan and L. Laudan (1989) have put forth a new model intended to solve the problem of disagreement, the problem of consensus, and the problem of innovation in science. In support of this model they cite the history of the acceptance of continental drift, or plate tectonics. In this discussion, I claim that this episode does not constitute an instance of their model. The historical evidence does not support this model. Indeed, closer examination seems to weaken it. I also (...) sketch an alternative model. (shrink)

Psychological-epistemic accounts take scientific progress to consist in the development of some psychological-epistemic attitude. Disagreements over what the relevant attitude is – true belief, knowledge, or understanding – divide proponents of thesemantic,epistemic,andnoeticaccounts of scientific progress, respectively. Proponents of all such accounts face a common challenge. On the face of it, only individuals have psychological attitudes. However, as I argue in what follows, increases in individual true belief, knowledge, and understanding are neither necessary nor sufficient for scientific progress. Rather than being (...) fatal to the semantic, epistemic, and noetic accounts, this objection shows that these accounts are most plausible when they take the psychological states relevant to scientific progress to be states of communities, rather than individuals. I draw on recent work in social epistemology to develop two ways in which communities can be the bearers of irreducible psychological-epistemic states. Each way yields a strategy by which proponents of one of the psychological-epistemic accounts might attempt to account for the social dimensions of scientific progress. While I present serious reasons for concern about the first strategy, I argue that the second strategy, at least, offers a promising path forward for a psychological-epistemic account of scientific progress. (shrink)

Issues of methodology are central to the philosophy of moral progress. However, the idea that effective moral methodology, as well as being instrumental to progress, might also constitute progress has not been adequately explored. This paper will critically assess the merits of this idea – what I call ‘pure proceduralism about moral progress’ – taking Philip Kitcher's recent theory of ‘democratic contractualism’ (2021) as a test case. An epistemology of pure procedural moral progress will be sketched: namely, a naturalised epistemology (...) of paradigmatic instances of moral progress. Assuming an ideal procedure exists and has been at least approximately instantiated (an empirical claim), we learn about its form by studying paradigms of historical moral progress. From this epistemological method will be derived theoretical constraints on what can count as a theory of moral progress per se: it must capture the core semantic constraints on the term ‘moral progress,’ those features without which we would not recognise a change as moral progress. While this poses a tougher challenge for pure proceduralism than for more traditional approaches to moral methodology, it will be concluded that the potential of pure proceduralism as a viable metaethics of moral progress remains an exciting open question. (shrink)

This paper aims to develop an account of the pursuitworthiness of models based on a view of models as epistemic tools. This paper is motivated by the historical question of why, in the 1960s, when many scientists hardly found QSAR models attractive, some pharmaceutical scientists pursued Quantitative Structure–Activity Relationship (QSAR) models despite the lack of potential for theoretical development or empirical success. This paper addresses this question by focusing on how models perform their heuristic functions as epistemic tools rather than (...) as potential theories. I argue that models perform their heuristic function by “constructing” phenomena from data in the sense that they allow the model users who interact with the medium of the models to recognise the phenomena as such. The constructed phenomena assist model users in identifying which conditional hypotheses that are focused on low-level regularities concerning entities such as chemical compounds are more “testworthy,” a concept that links the costs associated with hypothesis testing with the fertility of the hypothesis. (shrink)

Intellectual courage requires acting to promote epistemic goods despite significant risk of harm. Courage is distinguished from recklessness and cowardice because the expected epistemic benefit of a courageous action outweighs (in some sense) the threatened harm. Sometimes, however, inquirers pursue theories that are not best supported by their current evidence. For these inquirers, the expected epistemic benefit of their actions cannot be explained by appeal to their evidence alone. The probability of pursuing the true theory cannot contribute enough to the (...) expected epistemic benefit for the action to count as courageous rather than reckless. Thus, there must be some other epistemic consideration which favors their action, besides evidence for their theory. I argue that the proper account of intellectual courage requires recognition of inquisitive reasons: a distinct category of epistemic reasons which concern successful inquiry. This category includes reasons to think a theory itself is promising, e.g., that the theory suggests potentially fruitful new research. It also includes social epistemic reasons, e.g., that pursuing a theory will improve the distribution of cognitive labor. Inquisitive reasons help explain why researchers who pursue improbable theories count as intellectually courageous, rather than reckless. The expected epistemic benefit of an action is partially determined by the inquisitive reasons in its favor. On my account, intellectually courageous inquiry requires acting in a way that is sensitive to inquisitive reasons. (shrink)

The one thing upon which we can all agree is that just over ten years ago a major revolution occurred in the science of geology. Geologists switched from accepting a static earth-picture, to endorsing a vision of an earth with its surface constantly in motion. (Cox [4]; Hallam [12]; Marvin [28]; Wilson [56]). It is true that early in this century the German geologist Alfred Wegener argued that the continents as we today find them have “drifted” to their positions from (...) other positions widely different. However, other than amongst a number of scientists drawn almost exclusively from the Southern Hemisphere, his ideas fell on deaf — or more precisely, contemptuous — ears. Then in the mid 1960’s, almost literally overnight, the geological community swung around and embraced the hypothesis of continental drift, or what we shall see is perhaps more accurately called “plate tectonics”. (shrink)

Philosophers of science have in recent years become increasingly interested in the notion of interdisciplinarity. One important form interdisciplinarity can take is that of a dynamic exchange of problems and solutions between disciplines—what has recently been called problem-feeding. On this model problems arising within specific disciplines are sometimes solved more effectively by, or in collaboration with, other disciplines. In this paper we explore this model as a framework for thinking about, and actively structuring, interdisciplinary research. We point to the applicability (...) of the problem-feeding model, and to some of the prerequisites of problem-feeding interdisciplinarity, highlighting in particular the harmonisation of goals and the establishment of mutual trust between disciplines. (shrink)

Predictive processing (PP) and embodied cognition (EC) have emerged as two influential approaches within cognitive science in recent years. Not only have PP and EC been heralded as “revolutions” and “paradigm shifts” but they have motivated a number of new and interesting areas of research. This has prompted some to wonder how compatible the two views might be. This paper looks to weigh in on the issue of PP-EC compatibility. After outlining two recent proposals, I argue that further clarity can (...) be achieved on the issue by considering a model of scientific progress. Specifically, I suggest that Larry Laudan’s “problem solving model” can provide important insights into a number of outstanding challenges that face existing accounts of PP-EC compatibility. I conclude by outlining additional implications of the problem solving model for PP and EC more generally. (shrink)

The predictive processing account of action, cognition, and perception is one of the most influential approaches to unifying research in cognitive science. However, its promises of grand unification will remain unfulfilled unless the account becomes theoretically robust. In this paper, we focus on empirical commitments of PP, since they are necessary both for its theoretical status to be established and for explanations of individual phenomena to be falsifiable. First, we argue that PP is a varied research tradition, which may employ (...) various kinds of scientific representations, differing in the scope of empirical commitments they entail. Two major perspectives on PP qua cognitive theory may then be distinguished: generalized vs. hierarchical. The first one fails to provide empirical detail, and the latter constrains possible physical implementations. However, we show that even hierarchical PP is insufficiently restrictive to disallow incorrect models and may be adjusted to explain any neurocognitive phenomenon–including non-existent or impossible ones–through flexible adjustments. This renders PP a universal modeling tool with an unrestricted number of degrees of freedom. Therefore, in contrast with declarations of its proponents, it should not be understood as a unifying theoretical perspective, but as a computational framework, possibly informing further theory development in cognitive science. (shrink)

This article aims to defend a novel account of pluralism in economics. First, it argues that what justifies pluralism is its epistemological benefits. Second, it acknowledges that pluralism has limits, and defends reasonable pluralism, or the view that we should only accept those theories and methods that can be justified by their communities with reasons that other communities can accept. Clearly, reasonable pluralism is an ideal, which requires economists of different persuasions to respect certain norms of communication while evaluating each (...) other’s theories. The article ends with a discussion of the conditions under which reasonable communication becomes possible. (shrink)

Theories of different and independent types of intelligence constitute a Lakatosian research program, as they all claim that human intelligence has a multidimensional structure, consisting of independent cognitive abilities, and that human intelligence is not characterized by any general ability that is of greater practical importance, or that has greater predictive validity, than other, more specialized cognitive abilities. This paper argues that the independent intelligences research program is degenerating, since it has not led to novel, empirically corroborated predictions. However, despite (...) its flaws, the program provides an illustrative example of some of the philosophical problems that inhere in Lakatos’s so-called “methodology”. Indeed, Lakatos’s conceptions of the negative heuristic, the positive heuristic, and the relationship between scientific appraisal and advice are all vulnerable to objections. The upshot is that theories of independent intelligences indeed teach us more about philosophy of science than about the nature of human intelligence. (shrink)

The demarcation between science and pseudoscience is a long-standing problem in philosophy of science. Although philosophers have been hesitant to engage in this project since Larry Laudan announce...

Contemporary debate surrounding the nature of scientific progress has focused upon the precise role played by justification, with two realist accounts having dominated proceedings. Recently, however, a third realist account has been put forward, one which offers no role for justification at all. According to Finnur Dellsén’s (Stud Hist Philos Sci Part A 56:72–83, 2016) noetic account, science progresses when understanding increases, that is, when scientists grasp how to correctly explain or predict more aspects of the world that they could (...) before. In this paper, we argue that the noetic account is severely undermotivated. Dellsén provides three examples intended to show that understanding can increase absent the justification required for true belief to constitute knowledge. However, we demonstrate that a lack of clarity in each case allows for two contrasting interpretations, neither of which serves its intended purpose. On the first, the agent involved lacks both knowledge and understanding; and, on the second, the agent involved successfully gains both knowledge and understanding. While neither interpretation supports Dellsén’s claim that understanding can be prised apart from knowledge, we argue that, in general, agents in such cases ought to be attributed neither knowledge nor understanding. Given that the separability of knowledge and understanding is a necessary component of the noetic account, we conclude that there is little support for the idea that science progresses through increasing understanding rather than the accumulation of knowledge. (shrink)

This paper presents the results of an empirical study following up on Mizrahi (2021). Using the same methods of text mining and corpus analysis used by Mizrahi (2021), we test empirically a philosophical account of scientific progress that Mizrahi (2021) left out of his empirical study, namely, the so-called functional-internalist account of scientific progress according to which the aim or goal or scientific research is to solve problems. In general, our results do not lend much empirical evidence in support of (...) the problem-solving model of scientific progress over the other philosophical accounts of scientific progress (namely, the epistemic, noetic, and semantic accounts of scientific progress) tested in Mizrahi (2021) and in this follow-up study. Of all the subjects in the JSTOR database we have tested in this study, however, Mathematics is an interesting exception as far as the problem-solving model of scientific progress is concerned. For, in Mathematics alone, we have found that there is significantly more talk of the aims and/or goals of research in terms of solutions than in terms of truth, knowledge, or understanding. (shrink)

What is scientific progress? This paper advances an interpretation of this question, and an account that serves to answer it. Roughly, the question is here understood to concern what type of cognitive change with respect to a topic X constitutes a scientific improvement with respect to X. The answer explored in the paper is that the requisite type of cognitive change occurs when scientific results are made publicly available so as to make it possible for anyone to increase their understanding (...) of X. This account is briefly compared to two rival accounts of scientific progress, based respectively on increasing truthlikeness and accumulating knowledge, and is argued to be preferable to both. (shrink)

Is there progress in philosophy? If so, how much? Philosophers have recently argued for a wide range of answers to these questions, from the view that there is no progress whatsoever to the view that philosophy has provided answers to all the big philosophical questions. However, these views are difficult to compare and evaluate, because they rest on very different assumptions about the conditions under which philosophy would make progress. This paper looks to the comparatively mature debate about scientific progress (...) for inspiration on how to formulate four distinct accounts of philosophical progress, in terms of truthlikeness, problem-solving, knowledge, and understanding. Equally importantly, the paper outlines a common framework for how to understand and evaluate these accounts. We distill a series of lessons from this exercise, to help pave the way for a more fruitful discussion about philosophical progress in the future. (shrink)

Psychological-epistemic accounts take scientific progress to consist in the development of some psychological-epistemic attitude. Disagreements over what the relevant attitude is – true belief, knowledge, or understanding – divide proponents of thesemantic,epistemic,andnoeticaccounts of scientific progress, respectively. Proponents of all such accounts face a common challenge. On the face of it, only individuals have psychological attitudes. However, as I argue in what follows, increases in individual true belief, knowledge, and understanding are neither necessary nor sufficient for scientific progress. Rather than being (...) fatal to the semantic, epistemic, and noetic accounts, this objection shows that these accounts are most plausible when they take the psychological states relevant to scientific progress to be states of communities, rather than individuals. I draw on recent work in social epistemology to develop two ways in which communities can be the bearers of irreducible psychological-epistemic states. Each way yields a strategy by which proponents of one of the psychological-epistemic accounts might attempt to account for the social dimensions of scientific progress. While I present serious reasons for concern about the first strategy, I argue that the second strategy, at least, offers a promising path forward for a psychological-epistemic account of scientific progress. (shrink)

We model scientific theories as Bayesian networks. Nodes carry credences and function as abstract representations of propositions within the structure. Directed links carry conditional probabilities and represent connections between those propositions. Updating is Bayesian across the network as a whole. The impact of evidence at one point within a scientific theory can have a very different impact on the network than does evidence of the same strength at a different point. A Bayesian model allows us to envisage and analyze the (...) differential impact of evidence and credence change at different points within a single network and across different theoretical structures. (shrink)

This paper articulates and defends three interconnected claims: first, that the debate on the role of values for science misses a crucial dimension, the institutional one; second, that institutions occupy the intermediate level between scientific activities and values and that they are to be systematically integrated into the analysis; third, that the appraisal of the institutions of science with respect to values should be undertaken within the premises of a comparative approach rather than an ideal approach. Hence, I defend the (...) view that the issue be framed in reference to the following question: "What kind of institutional rules should be in place in order for the scientific process to unfold in such a way that the values that we deem more important come to the fore?" Addressing this concern is equivalent to conducting a debate on institutions and their role for science. (shrink)

In this paper, I offer an explication of the notion of local explanation. In the literature, local explanations are considered as metaphysically and methodologically satisfactory: local explanations reveal the contingency of science and provide a methodologically sound historiography of science. However, the lack of explication of the notion of local explanation makes these claims difficult to assess. The explication provided in this paper connects the degree of locality of an explanans to the degree of contingency of the explanandum. Moreover, the (...) explication is shown to be compatible with the methodological need for a general consideration in the historiography of science. In this way, the explication satisfies the need to explicate an important notion, connects local explanations and contingency, and enables us to see how local explanations and general considerations can be connected. However, the explication also sheds critical light on many claims and expectations that are associated with local explanations and their satisfactoriness. (shrink)

A recent issue of Topics in Cognitive Science featured 11 thoughtful commentaries responding to our article “What happened to cognitive science?” (Núñez et al., 2019). Here, we identify several themes that arose in those commentaries and respond to each. Crucial to understanding our original article is the fundamental distinction between multidisciplinary and interdisciplinary endeavors: Cognitive science began (and has stayed) as multidisciplinary but has failed to move on to form a cohesive interdisciplinary field. We clarify and elaborate our original argument (...) and reiterate the importance of a data‐driven evaluation of the current status of the field, which exhibits a marked disciplinary imbalance, a lack of a coherent conceptual core, and a striking absence of a consistent curriculum in the institutions that grant degrees in this domain. Half a century after the creation of cognitive science, it may now be a good time to revisit goals and visions for how to best approach the ever‐fascinating scientific study of the mind(s). (shrink)

Predictive processing (PP) has been repeatedly presented as a unificatory account of perception, action, and cognition. In this paper, we argue that this is premature: As a unifying theory, PP fails to deliver general, simple, homogeneous, and systematic explanations. By examining its current trajectory of development, we conclude that PP remains only loosely connected both to its computational framework and to its hypothetical biological underpinnings, which makes its fundamentals unclear. Instead of offering explanations that refer to the same set of (...) principles, we observe systematic equivocations in PP‐based models, or outright contradictions with its avowed principles. To make matters worse, PP‐based models are seldom empirically validated, and they are frequently offered as mere just‐so stories. The large number of PP‐based models is thus not evidence of theoretical progress in unifying perception, action, and cognition. On the contrary, we maintain that the gap between theory and its biological and computational bases contributes to the arrested development of PP as a unificatory theory. Thus, we urge the defenders of PP to focus on its critical problems instead of offering mere re‐descriptions of known phenomena, and to validate their models against possible alternative explanations that stem from different theoretical assumptions. Otherwise, PP will ultimately fail as a unified theory of cognition. (shrink)

I argue that recognizing a distinct doxastic attitude called endorsement, along with the epistemic norms governing it, solves the self-undermining problem for conciliationism about disagreement. I provide a novel account of how the self-undermining problem works by pointing out the auxiliary assumptions the objection relies on. These assumptions include commitment to certain epistemic principles linking belief in a theory to following prescriptions of that theory. I then argue that we have independent reason to recognize the attitude of endorsement. Endorsement is (...) the attitude of resilient and committed advocacy which is appropriate for researchers to have toward their own theory. Recognizing the importance of endorsement, and of its resiliency, gives us reason to deny the epistemic principles that serve as auxiliary assumptions in the self-undermining objection. This defuses the objection, and provides additional support for the theory of endorsement. (shrink)

We report the results of a study that investigated the views of researchers working in seven scientific disciplines and in history and philosophy of science in regard to four hypothesized dimensions of scientific realism. Among other things, we found that natural scientists tended to express more strongly realist views than social scientists, that history and philosophy of science scholars tended to express more antirealist views than natural scientists, that van Fraassen’s characterization of scientific realism failed to cluster with more standard (...) characterizations, and that those who endorsed the pessimistic induction were no more or less likely to endorse antirealism. (shrink)

Recent work takes both philosophical and scientific progress to consist in acquiring factive epistemic states such as knowledge. However, much of this work leaves unclear what entity is the subject of these epistemic states. Furthermore, by focusing only on states like knowledge, we overlook progress in intermediate cases between ignorance and knowledge—for example, many now celebrated theories were initially so controversial that they were not known. -/- This paper develops an improved framework for thinking about intellectual progress. Firstly, I argue (...) that we should think of progress relative to the epistemic position of an intellectual community rather than individual inquirers. Secondly, I show how focusing on the extended process of inquiry (rather than the mere presence or absence of states like knowledge) provides a better evaluation of different types of progress. This includes progress through formulating worthwhile questions, acquiring new evidence, and increasing credence on the right answers to these questions. I close by considering the ramifications for philosophical progress, suggesting that my account supports rejecting the most negative views while allowing us to articulate different varieties of optimism and pessimism. (shrink)

To identify and conceptualize research problems in science, philosophers and often scientists rely on classical accounts of problems that focus on intellectual problems defined in relation to theories. Recently, philosophers have begun to study the structures and functions of research problems not defined in relation to theories. Furthermore, scientists have long pursued research problems often labeled as practical or applied. As yet, no account of problems specifies the description of both so-called intellectual problems and so-called applied problems. This article proposes (...) a new conceptual framework of problems that accounts both for intellectual aspects of problems and for their practical or applied aspects. I illustrate the account with an example of a recent research project from evolutionary biology, and I indicate further routes by that to develop the account, especially in connection to empirical studies of science. (shrink)

Scientists, philosophers, and other researchers commonly assert their theories. This is surprising, as there are good reasons for skepticism about theories in cutting-edge research. I propose a new account of assertion in research contexts that vindicates these assertions. This account appeals to a distinct propositional attitude called endorsement, which is the rational attitude of committed advocacy researchers have to their theories. The account also appeals to a theory of conversational pragmatics known as the Question Under Discussion model, or QUD. Hence, (...) I call the theory the EQUD model. Motivating this account is a recognition that the speech act of assertion has two roles to play in research contexts. The first is the advocacy role, in which researchers assert a theory in order to advocate for it. The second is the evidential role, which is used to add to the common stock of information available to a field of inquiry. The EQUD model provides an account of warranted assertion for both these roles in research contexts. This success provides support for the theory of endorsement. It also provides support for information updating accounts of assertion. (shrink)

The “Cosmological Constant Problem” is widely considered a crisis in contemporary theoretical physics. Unfortunately, the search for its resolution is hampered by open disagreement about what is, strictly, the problem. This disagreement stems from the observation that the CCP is not a problem within any of our current theories, and nearly all of the details of those future theories for which the CCP could be made a problem are up for grabs. Given this state of affairs, I discuss how one (...) ought to make sense of the role of the CCP in physics and generalize some lessons from it. (shrink)

This article develops and defends a new functional approach to scientific progress. I begin with a review of the problems of the traditional functional approach. Then I propose a new functional account of scientific progress, in which scientific progress is defined in terms of usefulness of problem defining and problem solving. I illustrate and defend my account by applying it to the history of genetics. Finally, I highlight the advantages of my new functional approach over the epistemic and semantic approaches (...) and dismiss some potential objections to my approach. (shrink)

We offer a new account of the role of values in theory choice that captures a temporal dimension to the values themselves. We argue that non-epistemic values sometimes serve as “inquiry tickets,” justifying scientists’ pursuit of certain questions in the short run, while the answers to those questions mitigate transient underdetermination in the long run. Our account of inquiry tickets shows that the role of non-epistemic values need not be restricted to belief or acceptance in order to be relevant to (...) hypothesis choice: the relevance of non-epistemic values to a particular cognitive attitude with respect to h vary over time. (shrink)

We present two case studies from contemporary biology in which we observe conflicts between established and emerging approaches. The first case study discusses the relation between molecular biology and systems biology regarding the explanation of cellular processes, while the second deals with phylogenetic systematics and the challenge posed by recent network approaches to established ideas of evolutionary processes. We show that the emergence of new fields is in both cases driven by the development of high-throughput data generation technologies and the (...) transfer of modeling techniques from other fields. New and emerging views are characterized by different philosophies of nature, i.e. by different ontological and methodological assumptions and epistemic values and virtues. This results in a kind of conflict we call “epistemic competition” that manifests in two ways: On the one hand, opponents engage in mutual critique and defense of their fundamental assumptions. On the other hand, they compete for the acceptance and integration of the knowledge they provide by a broader scientific community. Despite an initial rhetoric of replacement, the views as well as the respective audiences come to be seen as more clearly distinct during the course of the debate. Hence, we observe—contrary to many other accounts of scientific change—that conflict results in the formation of new niches of research, leading to co-existence and perceived complementarity of approaches. Our model thus contributes to the understanding of the pluralization of the scientific landscape. (shrink)

In this paper, I offer an analysis of the radical disagreement over the adequacy of string theory. The prominence of string theory despite its notorious lack of empirical support is sometimes explained as a troubling case of science gone awry, driven largely by sociological mechanisms such as groupthink (e.g. Smolin 2006). Others, such as Dawid (2013), explain the controversy by positing a methodological revolution of sorts, according to which string theorists have quietly turned to nonempirical methods of theory assessment given (...) the technological inability to directly test the theory. The appropriate response, according to Dawid, is to acknowledge this development and widen the canons of acceptable scientific methods. As I’ll argue, however, the current situation in fundamental physics does not require either of these responses. Rather, as I’ll suggest, much of the controversy stems from a failure to properly distinguish the “context of justification” from the “context of pursuit”. Both those who accuse string theorists of betraying the scientific method and those who advocate an enlarged conception of scientific methodology objectionably conflate epistemic justification with judgements of pursuit-worthiness. Once we get clear about this distinction and about the different norms governing the two contexts, the current situation in fundamental physics becomes much less puzzling. After defending this diagnosis of the controversy, I’ll show how the argument patterns that have been posited by Dawid as constituting an emergent methodological revolution in science are better off if reworked as arguments belonging to the context of pursuit. (shrink)

While some form of evaluation has always been employed in science (e.g. peer review, hiring), formal systems of evaluation of research and researchers have recently come to play a more prominent role in many countries because of the adoption of new models of governance. According to such models, the quality of the output of both researchers and their institutions is measured, and issues such as eligibility for tenure or the allocation of public funding to research institutions crucially depends on the (...) outcomes of such measures. However, concerns have been raised over the risk that such evaluation may be threatening epistemic pluralism by penalizing the existent heterodox schools of thought and discouraging the pursuit of new ones. It has been proposed that this may happen because of epistemic bias favouring mainstream research programmes. In this paper, I claim that (1) epistemic pluralism is desirable and should be preserved; (2) formal evaluation exercises may threaten epistemic pluralism because they may be affected by some form of epistemic bias; therefore, (3) to preserve epistemic pluralism, we need some strategy to actively dampen epistemic bias. (shrink)

In this paper, I argue that computationalism is a progressive research tradition. Its metaphysical assumptions are that nervous systems are computational, and that information processing is necessary for cognition to occur. First, the primary reasons why information processing should explain cognition are reviewed. Then I argue that early formulations of these reasons are outdated. However, by relying on the mechanistic account of physical computation, they can be recast in a compelling way. Next, I contrast two computational models of working memory (...) to show how modeling has progressed over the years. The methodological assumptions of new modeling work are best understood in the mechanistic framework, which is evidenced by the way in which models are empirically validated. Moreover, the methodological and theoretical progress in computational neuroscience vindicates the new mechanistic approach to explanation, which, at the same time, justifies the best practices of computational modeling. Overall, computational modeling is deservedly successful in cognitive science. Its successes are related to deep conceptual connections between cognition and computation. Computationalism is not only here to stay, it becomes stronger every year. (shrink)

This article highlights a use of analogies in science that so far has received relatively little systematic discussion: providing reasons for pursuing a model or theory. Using the development of the liquid drop model as a test case, I critically assess two extant pursuit worthiness accounts: that analogies justify pursuit by supporting plausibility arguments and that analogies can serve as a guide to potential theoretical unification. Neither of these fit the liquid drop model case. Instead, I develop an alternative account, (...) based on the idea that analogies facilitate the transfer of a well-understood modelling strategy to a new domain. 1Introduction2Case Study: The Development of the Liquid Drop Model3Plausibility Accounts 3.1Bartha on plausibility and analogical inference3.2Plausibility and the drop analogy4Analogies as a Guide to Unification5Generative Accounts 5.1Analogy-based modelling strategies5.2Did analogies play a merely generative role?6A New Pursuit Worthiness Account of Analogies 6.1Transferring understanding-with through analogies6.2Understanding-with and the liquid drop model7Conclusion. (shrink)

Scientists are constantly making observations, carrying out experiments, and analyzing empirical data. Meanwhile, scientific theories are routinely being adopted, revised, discarded, and replaced. But when are such changes to the content of science improvements on what came before? This is the question of scientific progress. One answer is that progress occurs when scientific theories ‘get closer to the truth’, i.e. increase their degree of truthlikeness. A second answer is that progress consists in increasing theories’ effectiveness for solving scientific problems. A (...) third answer is that progress occurs when the stock of scientific knowledge accumulates. A fourth and final answer is that scientific progress consists in increasing scientific understanding, i.e. the capacity to correctly explain and reliably predict relevant phenomena. This paper compares and contrasts these four accounts of scientific progress, considers some of the most prominent arguments for and against each account, and briefly explores connections to different forms of scientific realism. (shrink)

Sample (2015) argues that scientists ought not to believe that their theories are true because they cannot fulfill the epistemic obligation to take the diachronic perspective on their theories. I reply that Sample’s argument imposes an inordinately heavy epistemic obligation on scientists, and that it spells doom not only for scientific theories but also for observational beliefs and philosophical ideas that Samples endorses. I also delineate what I take to be a reasonable epistemic obligation for scientists. In sum, philosophers ought (...) to impose on scientists only an epistemic standard that they are willing to impose on themselves. (shrink)

I present a recent historical case from cosmology—the story of inflationary cosmology—and on its basis argue that solving explanatory problems is a reliable method for making progress in science. In particular, I claim that the success of inflationary theory at solving its predecessor’s explanatory problems justified the theory epistemically, even in advance of the development of novel predictions from the theory and the later confirmation of those predictions.

It is valuable for inquiry to have researchers who are committed advocates of their own theories. However, in light of pervasive disagreement, such a commitment is not well explained by the idea that researchers believe their theories. Instead, this commitment, the rational attitude to take toward one’s favored theory during the course of inquiry, is what I call endorsement. Endorsement is a doxastic attitude, but one which is governed by a different type of epistemic rationality. This inclusive epistemic rationality is (...) sensitive to reasons beyond those to think the particular proposition in question is true. Instead, it includes extrinsic epistemic reasons, which concern the health of inquiry more generally. Such extrinsic reasons include the distribution of cognitive labor that a researcher will contribute to by endorsing a particular theory. Recognizing endorsement and inclusive epistemic rationality thus allows us to smooth a tension between individual rationality and collective rationality. It does so by showing how it can be epistemically rational to endorse a theory on the basis of the way this endorsement will benefit collective inquiry. I provide a decision theoretic treatment for inclusive epistemic rationality and endorsement which illustrates how this can be accomplished. (shrink)

We introduce a novel point of view on the “models as mediators” framework in order to emphasize certain important epistemological questions about models in science which have so far been little investigated. To illustrate how this perspective can help answer these kinds of questions, we explore the use of simplified models in high energy physics research beyond the Standard Model. We show in detail how the construction of simplified models is grounded in the need to mitigate pressing epistemic problems concerning (...) the uncertainty inherent in the present theoretical and experimental contexts. (shrink)

Human need and related concepts such as basic needs have long been part of the implicit conceptual foundation for social work theory, practice, and research. However, while the published literature in social work has long stressed social justice, and has incorporated discussion of human rights, human need has long been both a neglected and contested concept. In recent years, the explicit use of human needs theory has begun to have a significant influence on the literature in social work.