The machine conception of the organism (MCO) is one of the most pervasive notions in modern biology. However, it has not yet received much attention by philosophers of biology. The MCO has its origins in Cartesian natural philosophy, and it is based on the metaphorical redescription of the organism as a machine. In this paper I argue that although organisms and machines resemble each other in some basic respects, they are actually very different kinds of systems. I submit that the (...) most significant difference between organisms and machines is that the former are intrinsically purposive whereas the latter are extrinsically purposive. Using this distinction as a starting point, I discuss a wide range of dissimilarities between organisms and machines that collectively lay bare the inadequacy of the MCO as a general theory of living systems. To account for the MCO’s prevalence in biology, I distinguish between its theoretical, heuristic, and rhetorical functions. I explain why the MCO is valuable when it is employed heuristically but not theoretically, and finally I illustrate the serious problems that arise from the rhetorical appeal to the MCO. (shrink)

Our aim in the present paper is to approach the nature of life from the perspective of autonomy, showing that this perspective can be helpful for overcoming the traditional Cartesian gap between the physical and cognitive domains. We first argue that, although the phenomenon of life manifests itself as highly complex and multidimensional, requiring various levels of description, individual organisms constitute the core of this multifarious phenomenology. Thereafter, our discussion focuses on the nature of the organization of individual living entities, (...) proposing autonomy as the main concept to grasp it. In the second part of the article we show how autonomy is also fundamental to explaining major evolutionary transitions, in an attempt to rethink evolution from the point of view of the organizational structure of the entities/organisms involved. This gives further support to the idea of autonomy not only as a key to understanding life in general but also the complex expressions of it that we observe on our planet. Finally, we suggest a possible general principle that underlies those evolutionary transitions, which allow for the open-ended redefinition of autonomous systems: namely, the relative dynamic decoupling that must be articulated among distinct parts, modules or modes of operation in these systems. (shrink)

My goal in this paper is to provide characterizations of matter, form and constituency in a way that avoids what I take to be the three main drawbacks of other hylomorphic theories: (i) commitment to the universal-particular distinction; (ii) commitment to a primitive or problematic notion of inherence or constituency; (iii) inability to identify viable candidates for matter and form in nature, or to characterize them in terms of primitives widely regarded to be intelligible.

What precisely does aristotle mean when he asserts that something is (or comes to be) "for" "the" "sake" "of" something? I suggest that the answer to this question may be found by examining aristotle's position on the problem of reduction in biology, As it arises within his own scientific "and" "philosophical" context. I discuss the role of the concepts of "nature" and "potential" in aristotelian scientific explanation, And reformulate the reduction problem in that light. I answer the main question by (...) establishing that aristotle holds an "irreducibility" thesis in regard to the generation and development of a living organism, And that this thesis is the core of his conception of final causality. I conclude by arguing that aristotle's teleology is fundamentally "empirical" in character, And not an a priori doctrine brought "to" the study of nature. (shrink)

There is no broadly accepted definition of ‘life.’ Suggested definitions face problems, often in the form of robust counter-examples. Here we use insights from philosophical investigations into language to argue that defining ‘life’ currently poses a dilemma analogous to that faced by those hoping to define ‘water’ before the existence of molecular theory. In the absence of an analogous theory of the nature of living systems, interminable controversy over the definition of life is inescapable.

The distinction between the essential and the accidental characteristics of a thing should be understood not in modal terms (the received view) nor in definitional terms (Fine’s recent proposal) but as follows: an essential characteristic of a thing is one that is not explained by any other of that thing’s characteristics, and an accidental characteristic of a thing is one that is so explained. Various versions of this proposal can be formulated.

Aristotelian metaphysics is currently undergoing something of a renaissance. This volume brings together fourteen essays from leading philosophers who are sympathetic to this conception of metaphysics, which takes its cue from the idea that metaphysics is the first philosophy. The primary input from Aristotle is methodological, but many themes familiar from his metaphysics will be discussed, including ontological categories, the role and interpretation of the existential quantifier, essence, substance, natural kinds, powers, potential, and the development of life. The volume mounts (...) a strong challenge to the type of ontological deflationism which has recently gained a strong foothold in analytic metaphysics. It will be a useful resource for scholars and advanced students who are interested in the foundations and development of philosophy. (shrink)

Stuart Kauffman here presents a brilliant new paradigm for evolutionary biology, one that extends the basic concepts of Darwinian evolution to accommodate recent findings and perspectives from the fields of biology, physics, chemistry and mathematics. The book drives to the heart of the exciting debate on the origins of life and maintenance of order in complex biological systems. It focuses on the concept of self-organization: the spontaneous emergence of order widely observed throughout nature. Kauffman here argues that self-organization plays an (...) important role in the emergence of life itself and may play as fundamental a role in shaping life's subsequent evolution as does the Darwinian process of natural selection. Yet until now no systematic effort has been made to incorporate the concept of self-organization into evolutionary theory. The construction requirements which permit complex systems to adapt remain poorly understood, as is the extent to which selection itself can yield systems able to adapt more successfully. This book explores these themes. It shows how complex systems, contrary to expectations, can spontaneously exhibit stunning degrees of order, and how this order, in turn, is essential for understanding the emergence and development of life on Earth. Topics include the new biotechnology of applied molecular evolution, with its important implications for developing new drugs and vaccines; the balance between order and chaos observed in many naturally occurring systems; new insights concerning the predictive power of statistical mechanics in biology; and other major issues. Indeed, the approaches investigated here may prove to be the new center around which biologicalscience itself will evolve. The work is written for all those interested in the cutting edge of research in the life sciences. (shrink)

Of course, as scholars have long known, this example has serious limitations. For one thing, a substantial form, as the scholastics understood it, is much more dynamic than a mere shape. For example, the substantial form of an oak tree somehow explains how and why an oak tree can do everything that it does. So the substantial form of an oak tree could not be something as simple or crude as its shape. Nevertheless, the example of the bronze statue does (...) have the virtue of illustrating one of the chief advantages of hylomorphism as a philosophy of the human person. Although we can talk about the bronze and the shape of the statue, respectively, it still seems correct to say that the statue is exactly one thing, not two things. Likewise, although we can talk about the matter and the form of a human being, the hylomorphist insists that a human being is exactly one thing, not two things accidentally conjoined. (shrink)

I have learned a lot from Evan Thompson’s book — his scholarship is formidable, and his taste for relatively overlooked thinkers is admirable — but I keep stumbling over the strain induced by his selfassigned task of demonstrating that his heroes — Varela and Maturana, Merleau-Ponty and (now) Husserl, Oyama and Moss and others — have shattered the comfortable assumptions of orthodoxy, and outlined radical new approaches to the puzzles of life and mind. The irony is that Thompson is such (...) a clear and conscientious expositor that he makes it much easier for me to see that the ideas he expounds, while often truly excellent, are not really all that revolutionary, but, at best, valuable correctives to the sorts of oversimplifications that tend to get turned into mantras by sheer repetition in the textbooks and popular accounts of these topics in the media. Philosophers have a delicate task: squeezing the tacit assumptions and unnoticed implications out of every ill-considered dogma without lapsing into nitpicking or caricature. Thompson does better than most; he is not a gotcha!-monger or sea lawyer, but he does set up a few strawmen (strawpersons?) which I will duly expose as such, while showing that his revolutionaries are not really so revolutionary after all. Reformers are the bane of would-be rebels, of course, taking the wind out of their sails just as they get started, and in the cases I will discuss, reform-minded critics — myself among them — have already pointed out the caveats that pre-empt these assaults on orthodoxy. Might these caveats and concessions be mere lip service? Have the reformers underestimated the seriousness of the challenges, papering over the cracks that will in due course bring down their edifice? (shrink)

In several disciplines within science—evolutionary biology, molecular biology, astrobiology, synthetic biology, artificial life—and outside science—primarily ethics—efforts to define life have recently multiplied. However, no consensus has emerged. In this article, I argue that this is no accident. I propose a dilemma showing that the project of defining life is either impossible or pointless. The notion of life at stake in this project is either the folk concept of life or a scientific concept. In the former case, empirical evidence shows that (...) life cannot be defined. In the latter case, I argue that, although defining life may be possible, it is pointless. I conclude that scientists, philosophers, and ethicists should discard the project of defining life. (shrink)

Compiling twenty articles on the nature of life and on the objective of the natural sciences, this remarkable book complements Robert Rosen's groundbreaking Life Itself--a work that influenced a wide range of philosophers, biologists, linguists, and social scientists. In Essays on Life Itself, Rosen takes to task the central objective of the natural sciences, calling into question the attempt to create objectivity in a subjective world and forcing us to reconsider where science can lead us in the years to come.

In this accessible and fascinating book, Michel Morange draws on recent advances in molecular genetics, evolutionary biology, astrobiology, and other disciplines to find today’s answers to the question of life.

Classical neo-Darwinian explanations do not fully account for changes in biological forms, and new theories have emerged, primarily in maths and physics, that offer new approaches to the problem of the origin of life and phenomena of order in evolution. This volume focuses on the role of closure at various hierarchical levels as the catalyst between self-organization and selection. Participants addressed special areas of the closure problem such as autopoiesis and autocatalysis and function and selection, and semiosis. Presentations on physical (...) and mathematical modelling are included. The book seeks to clarify the role closure plays in explaining the emergence, development and evolution of structurally stable systems at the thermodynamic, chemical and biochemical, biological, psychological and cultural levels. (shrink)

This highly readable theory of life and its origins offers a non-technical discussion of a chemical perspective on the fundamental organisation of living systems. Essays on the biological and philosophical significance of Ganti's work of thirty years indicate not only its enduring theoretical significance, but also the continuing relevance and heuristic power of Ganti's insights.