This paper attempts to answer whether the property of “efficacy” can be attributed to constitutive rules. In particular, according to Di Lucia, I will point out some problems that the “semantic conception of efficacy” has concerning constitutive and regulative rules. Then, the main goal of the paper will be to reflect on the possibility of the efficacy of constitutive rules by means of a complex case that the semantic conception seems to disregard: The case of the cheater. Does the action (...) of the cheater show the inefficacy of constitutive rules? Does she play the game while breaking the rule? Can the semantic conception of efficacy explain this situation, or do we need a more flexible concept of efficacy that takes nomotropism into account? These are some of the questions I will try to answer. (shrink)

We have ignored for a century that the incompleteness of Quantum Theory (QT) is inseparable from the incompleteness of Special Relativity (RT). In this article, I claim that the latter has been gravely incomplete vis à vis the former from 1927 until today. But completing RT in the light of QT is not as simple as merely postulating nonlocality and stochasticity as “elements of reality” (which is de facto done by most physicists and pragmatic philosophers); otherwise, RT would not still (...) be in a “peaceful” conflict with QT after a century. Vice versa, I contend that QT is incomplete vis à vis RT, though not for the reasons claimed in the iconic EPR paper. We then show how to complete the Ontology, Foundation, and Structure of both RT and QT and merge them into an internally consistent embracive theory I call QR/TOPI. This theory offers a more cogent and simpler avenue to integrate RT with QT than positing exotic causal structures like ‘retrocausality’, ‘future-input dependence’, ‘superdeterminism’ – not to mention the extravagant ‘Many-Worlds’, ‘Many-Minds’, ‘Parallel-Lives’, and other interpretations of QT like Many-Histories, QBism, etc. -/- QR/TOPI provides the “radical conceptual renewal” wished by John Bell so as to integrate probability and nonlocality into an upgraded RT and, reciprocally, to integrate Frame-Invariance into QT while at the same time, as demanded by 2022 Nobel laureate Anton Zeilinger, providing basic physical meaning to the resulting encompassing theory. The old outcast notion of absolute simultaneity is resurrected without any conflict with Einstein’s relative simultaneity, while Frame-Invariance is preserved via our Quantumlike Transformation (QLT), which is an extension of the Lorentz Transformation (LT): QLT includes what LT excludes: nonlocality. -/- Section 1 examines the philosophical foundations of Space and Time, focusing on RT, its plethora of empirical validations, and the tenets which make it incompatible with QT. Section 2 incorporates stochasticity into RT. Sections 3 through 5 gradually introduce QR/TOPI for mono-, bi-, and tri-quanton systems, with full consideration of Bell Theorem, nonlocality, teleportation, and their implications. Section 6 attempts to review the current status quo. Section 7 makes the case for the incompleteness of RT and QT. Section 8 explains how to complete and integrate both theories so as to formally develop QR/TOPI. Finally, in Section 9, via multiple experimental setups, I zero in on Zeilinger’s basic question: “what does this really mean in a basic way?”. (shrink)

Emotions are an integral part of human cognition and they guide not only our understanding of the world but also our actions within it. As such, whether we soothe or flame an emotion is not inconsequential. Recent work in conversational AI has focused on responding empathetically to users, validating and soothing their emotions without a real basis. This AI-aided emotional regulation can have negative consequences for users and society, tending towards a one-noted happiness defined as only the absence of "negative" (...) emotions. We argue that we must carefully consider whether and how to respond to users' emotions. (shrink)

En el marco del V Congreso Internacional «La actualidad de Michel Foucault» celebrado en la Universidad Complutense de Madrid entre el 6 y el 8 de marzo de 2018, sostuvimos una interesante conversación con Daniel Lorenzini, investigador del pensamiento ético y político de Michel Foucault y editor de varios de sus cursos y conferencias publicadas en los últimos años en Francia. Discutimos sobre el estado actual de los archivos de Foucault adquiridos por la Biblioteca Nacional de Francia (BnF), algunos de (...) los diversos proyectos editoriales que se derivan del trabajo de archivo y análisis de los manuscritos del filósofo, la reciente e inesperada publicación de Les aveux de la chair y su relación con el proyecto de la Historia de la sexualidad tal como fue planteado en 1976, la relación de Foucault con Nietzsche respecto a sus lecturas de la subjetivación y el vínculo, no siempre evidente, entre ética y política a la luz de sus investigaciones sobre el filósofo francés. (shrink)

This paper explores the ways in which Cordwainer Smith’s short story “Under Old Earth” problematizes emotions, who/what has them, and who/what is granted moral status. Most importantly, however, “Under Old Earth” questions the primacy of happiness in human society, especially where happiness is understood as the absence of other (negative) emotions. As such, “Under Old Earth” challenges the notion, widely held in contemporary ethics, that our moral obligation to one another is mediated through the goal of the attainment of happiness. (...) Through this challenge, Smith’s short story speaks directly to the current understanding of emotion in the field of AI, and complicates what the goal of affective computing should be. (shrink)

Quality education needs quality teachers to achieve success. Thus, this study determined the factors related to the teachers’ performance in delivering the K to 12 Curriculum in the Narra del Sur district, Palawan, Philippines. A descriptive-correlational research design was employed, with a sample of 132 randomly selected public elementary teachers. The study used frequency counts and percentages, arithmetic mean and standard deviation, and Spearman’s rho to analyze and draw conclusions from the data. The findings revealed a correlation between the respondents’ (...) age and their utilization of teaching materials and ICT. The number of pupils taught was correlated with teachers’ commitment, while number of pupils taught, position, highest educational attainment, and length of service were related to the respondents’ performance. The main problem encountered by the respondents was excessive workloads, paperwork, and reports. To solve the problem teachers encountered in delivering the K to 12 Curriculum, the respondents preferred preparing a work plan and allocating time to daily and weekly tasks to avoid excessive workloads. These results may aid policymakers and curriculum developers in the Department of Education to make relevant enhancements to the factors that affect teachers’ performance in curriculum delivery. (shrink)

(ESP) Éste artículo tiene como objeto hacer una re-exposición de la teoría política de Baruch Espinosa (1632-1677) a la luz de su ontología –entendida ésta como una ontología materialista. Por lo tanto, se hará una interpretación materialista de la teoría política éste filósofo, desde un acercamiento al «Materialismo Filosófico» de Gustavo Bueno –específicamente, desde su filosofía política, como «materialismo político». Para esto, exploraremos brevemente ciertas ideas de su Tratado Político –teniendo en cuenta, desde luego, la Ética y el Tratado Teológico-Político. (...) Lidiaremos con ideas como «derecho natural», «Estado» o «Libertad», u otras ideas que irán saliendo a través de estas y que junto a la construcción de unas, dialécticamente criticará y destruirá otras –como «Pueblo», «Voluntad», «monarquía absoluta» etc. (ENG)("The Political Ontology of Spinoza") The aim of this article is the reexposition of Baruch Spinoza's (1632-1677) political theory, in the light of his ontology –understood as a materialist ontology. Therefore, we will make a materialist interpretation of the political theory of this philosopher, from an approach to Gustavo Bueno's «Philosophical Materialism» –specifically, from his political philosophy, as a «political materialism». For that goal, we will briefly explore certain ideas from his Political Treatise –of course, with the help of other works, like the Tractatus Theologico-Politicus and the Ethics. We will deal with ideas like «natural law», «State», «Freedom», and other ideas that may arise from those and in which construction, they dialectically criticize and destroy others –v.g., «People», «Will», «absolute monarchy» and so on. (shrink)

Most of us are either philosophically naïve scientists or scientifically naïve philosophers, so we misjudged Schrödinger’s “very burlesque” portrait of Quantum Theory (QT) as a profound conundrum. The clear signs of a strawman argument were ignored. The Ontic Probability Interpretation (TOPI) is a metatheory: a theory about the meaning of QT. Ironically, equating Reality with Actuality cannot explain actual data, justifying the century-long philosophical struggle. The actual is real but not everything real is actual. The ontic character of the Probable (...) has been elusive for so long because it cannot be grasped directly from experiment; it can only be inferred from physical setups that do not morph it into the Actual. In this Part III, Born’s Rule and the quantum formalism for the microworld are intuitively surmised from instances in our macroworld. The posited reality of the quanton’s probable states and properties is probed and proved. After almost a century, TOPI aims at setting the record straight: the so-called ‘Basis’ and ‘Measurement’ problems are ill-advised. About the first, all bases are legitimate regardless of state and milieu. As for the second, its premise is false: there is no need for a physical ‘collapse’ process that would convert many states into a single state. Under TOPI, a more sensible variant of the ‘measurement problem’ can be reformulated in non-anthropic terms as a real problem. Yet, as such, it is not part of QT per se and will be tackled in future papers. As for the mythical cat, the ontic state of a radioactive nucleus is not pure, so its evolution is not governed by Schrödinger’s equation – let alone the rest of his “hellish machine”. Einstein was right: “The Lord is subtle but not malicious”. However, ‘The Lord’ turned out to be much subtler than what Einstein and Schrödinger could have ever accepted. Part IV introduces QR/TOPI: a new theory that solves the century-old problem of integrating Special Relativity with Quantum Theory [1]. (shrink)

În prezent, în România, ca și în toate celelalte state euro-atlantice și în cadrul organizațiilor internaționale din care facem parte (NATO de exemplu), există o cerere puternică de analiști de informații „bine pregătiți”. Pentru a funcționa într-un mod eficient, structurile de informații au nevoie de analiști de informații eficienți, sau cu alte cuvinte, de analiști de informații bine pregătiți. Acesta este cazul comunității noastre naționale de informații, precum și al componentelor și structurilor sale. Necesitatea și importanța proiectului este în consecință (...) înrădăcinată în nevoia de analiști bine pregătiți și în misiunea lor centrală în domeniul informațiilor, și anume crearea de produse (informații de securitate) care să poată prezenta o înțelegere corectă și exactă a diferitelor procese, evenimente. și fenomene pentru factorii de decizie. Selecția celor vizați pentru a fi pregătiți necesită alcătuirea inițială a profilului unui analist de informații, selecția însăși necesitând orientarea către un profil psihologic compatibil cu misiunea pe care acesta va trebui să o îndeplinească și care posedă un nivel minim de analitică. abilitățile necesare, celelalte aspecte referitoare la instruirea analistului vor fi implementate într-un program numit pentru educația și formarea analiștilor de informații. (shrink)

Ignited by Einstein and Bohr a century ago, the philosophical struggle about Reality is yet unfinished, with no signs of a swift resolution. Despite vast technological progress fueled by the iconic Einstein/Podolsky/Rosen paper (EPR) [1] [2] [3], the intricate link between ontic and epistemic aspects of Quantum Theory (QT) has greatly hindered our grip on Reality and further progress in physical theory. Fallacies concealed by tortuous logical negations made EPR comprehension much harder than it could have been had Einstein written (...) it himself in German. EPR is plagued with preconceptions about what a physical property is, the 'Uncertainty Principle', and the Principle of Locality. Numerous interpretations of QT vis à vis Reality exist and are keenly disputed [4] [5] [6] [7] [8] [9] [10] [11]. This is the first of a series of articles arguing for a novel physical interpretation I call ‘The Ontic Probability Interpretation’ (TOPI). A gradual explanation of TOPI is given intertwined with a meticulous logico-philosophical scrutiny of EPR, with Part I focusing on the meaning of Einstein’s ‘incompleteness’ claim for QT: a conceptual confusion, a preconception about Reality, and a flawed dichotomy are shown to be severe obstacles for the EPR argument to succeed. Part II completes the analysis, proving EPR claim of ‘incompleteness’ for QT is fallacious [12]. Part III further develops TOPI, while scrutinizing the mythical ‘Schrödinger’s Cat’, as well as the ‘Basis’ and ‘Measurement’ pseudo-problems [13]. Part IV introduces QR/TOPI: a new theory that solves the century-old problem of integrating Special Relativity with Quantum Theory [14]. (shrink)

After identifying in Part I [1] a conceptual confusion (TCC), a Reality preconception (TRP1), and a fallacious dichotomy (TFD), the famous EPR/EPRB [2] [3] [4] [5] [6] argument for correlated ‘particles’ is now studied in the light of the Ontic Probability Interpretation of Quantum Theory (QT/TOPI). Another Reality preconception (TRP2) is found, showing that EPR used and ignored QT predictions in a single paralogism. Employing TFD and TRP2, EPR unveiled a contradiction veiled in its premises. By removing nonlocality from QT’s (...) Ontology [1] by fiat, EPR preordained its incompleteness. The Petitio Principii fallacy was at work from the outset. Einstein surmised the proper solution to his incompleteness/nonlocality dilemma in 1949 [7], but never abandoned his philosophical stance [8]. It is concluded that there are no definitions of Reality: we have to accept that Reality may not conform to our prejudices and, if an otherwise successful theory predicts what we do not believe in, no gedankenexperiment will help because our biases may slither through. Only actual experiments could assist in solving Einstein’s dilemma, as has been proven in the last 50 years. Notwithstanding, EPR is one of the most influential papers in history and has immensely sparked both conceptual and technological progress. Part III of this series further develops QT/TOPI, while scrutinizing the mythical ‘Schrödinger’s Cat’, as well as the ‘Basis’ and ‘Measurement’ pseudo-problems [9]. Part IV introduces QR/TOPI: a new theory that solves the century-old problem of integrating Special Relativity with Quantum Theory [10]. (shrink)

Globalisation has brought immense changes to the national and international economic structure. The digital revolution and ICT expansion positively impacted the sharing economy development. In this regard, the most avant-garde countries in sharing economy seem to be the advanced countries. However, transitory countries such as Albania are making satisfactory progress as well. While being part of some global cases of sharing economy, Albania is also experiencing domestic incentives related with. The sectors involved in sharing economy are affiliated to different domains, (...) including agriculture, tourism, healthcare, transportation, etc. Albania strongly embraced technology because of its relatively young population and the flexible education system adopting to the market needs. The Albanian government is doing well on the promotion and usage of public platforms, which are supportive of the sharing concept. Although not specifically for the sharing economy, the government of Albania has released some useful strategic plans to embed the necessary instruments and infrastructure to digitalisation. However, there is more to do for sharing economy in specific terms. The collaboration of three actors, businesses-academia-government, would bring to the Albanian market new capacities and additional added values. (shrink)

For philosophy to criticize the concept of reality requires self-criticism. Throughout history many thinkers that have systematized a critique of both reality and philosophy. In this article we will analyze the Kantian and Hegelian systems by showing the failure in their respective critique to exercise sufficient self-criticism, resulting in unfinished critiques. Going a step further, Tanabe’s proposal was to plunge philosophy into a kind of «absolute disruption» that would drive thought beyond itself by means of an absolute critique in which (...) being and nothingness are seen to interpenetrate each other, thus opening up the possibility of positing absolute nothingness as «a foundation that is not a foundation.». (shrink)

(ESP) Recensión del libro "Los ingenieros de Franco. Ciencia, catolicismo y Guerra Fría en el Estado franquista". Barcelona: Crítica, 2017, 317 páginas. La investigación principal de Lino Camprubí, nos ofrece una historia de la transformación del territorio español desde el punto de vista de las ciencias y las tecnologías. Constituye un ejemplo de constatación de la imbricación entre ciencia, tecnología y economía política –sin olvidar la religión. El libro muestra cómo el régimen franquista utilizó la ciencia y tecnología a su (...) alcance para la (re)construcción del país, pero también cómo esos mismos ingenieros construyeron la España franquista. // (ENG) Review of the book "Los ingenieros de Franco. Ciencia, catolicismo y Guerra Fría en el Estado franquista". (Franco's Engineers. Science, Catholicism and Cold War in the Francoist State) Barcelona: Crítica, 2017, 317 pp. The main research of Lino Camprubí, offers a history of the transformation of the Spanish territory from the point of view of science and technology. It constitutes an example of the verification of the imbrication between science, technology and political economy -without forgetting religion. The book shows how the francoist regime used the science and technology at its disposal for the (re)construction of the country, but also how those same engineers built Franco's Spain. (shrink)

(ESP) Reseña de 'El arte de Innovar', del filósofo español Javier Echeverría. (ENG) Review of the book 'El arte de Innovar' ('The art of Innovating'), written by the spanish philosopher Javier Echeverría.

Anger, far from being only a personal emotion, often signals a breakdown in existing societal structures like the justice system. This does not mean we should uncritically submit to our angry impulses, but it does mean that anger can reveal larger issues in the world worthy of attention. If we banish anger from the socio-political landscape, we risk losing its insights. To defend that claim, I turn to a range of sources from ancient China and Greece—philosophy, poetry, drama, and political (...) theory—that depict and analyze anger in a variety of situations and people. My basic claim is not that anger is simply “good” or “bad” but rather that it helps reveal and clarify our values, often pointing us towards real situations deserving of our ethical scrutiny. I situate the project amidst ongoing debates in analytic philosophy of emotions and feminist philosophy, joining the conceptual precision and clarity of the former with the latter’s attention to lived experience. Such cross-cultural, multidisciplinary conceptual analysis of anger parochializes Aristotelian understandings of anger by introducing different types and functions of anger. What role does anger play, for example, in a minister rebuking the king in an ancient Chinese court? How do Greek sources depict female anger differently than male anger, and why? By using ancient and comparative sources, I show how deeply anger is shaped by particular cultural and social structures, whilst remaining recognizably anger. (shrink)

Large language models (LLMs) reflect societal norms and biases, especially about gender. While societal biases and stereotypes have been extensively researched in various NLP applications, there is a surprising gap for emotion analysis. However, emotion and gender are closely linked in societal discourse. E.g., women are often thought of as more empathetic, while men's anger is more socially accepted. To fill this gap, we present the first comprehensive study of gendered emotion attribution in five state-of-the-art LLMs (open- and closed-source). We (...) investigate whether emotions are gendered, and whether these variations are based on societal stereotypes. We prompt the models to adopt a gendered persona and attribute emotions to an event like 'When I had a serious argument with a dear person'. We then analyze the emotions generated by the models in relation to the gender-event pairs. We find that all models consistently exhibit gendered emotions, influenced by gender stereotypes. These findings are in line with established research in psychology and gender studies. Our study sheds light on the complex societal interplay between language, gender, and emotion. The reproduction of emotion stereotypes in LLMs allows us to use those models to study the topic in detail, but raises questions about the predictive use of those same LLMs for emotion applications. (shrink)

Emotions are a central aspect of communication. Consequently, emotion analysis (EA) is a rapidly growing field in natural language processing (NLP). However, there is no consensus on scope, direction, or methods. In this paper, we conduct a thorough review of 154 relevant NLP publications from the last decade. Based on this review, we address four different questions: (1) How are EA tasks defined in NLP? (2) What are the most prominent emotion frameworks and which emotions are modeled? (3) Is the (...) subjectivity of emotions considered in terms of demographics and cultural factors? and (4) What are the primary NLP applications for EA? We take stock of trends in EA and tasks, emotion frameworks used, existing datasets, methods, and applications. We then discuss four lacunae: (1) the absence of demographic and cultural aspects does not account for the variation in how emotions are perceived, but instead assumes they are universally experienced in the same manner; (2) the poor fit of emotion categories from the two main emotion theories to the task; (3) the lack of standardized EA terminology hinders gap identification, comparison, and future goals; and (4) the absence of interdisciplinary research isolates EA from insights in other fields. Our work will enable more focused research into EA and a more holistic approach to modeling emotions in NLP. (shrink)

this book concerns the debates on the functions of "imagination" (phantasia, imaginatio) in the arousal of passions in the Aristotelian and post-Aristotelian traditions till the XVIIth Century. The simple fact that often a mental representation is followed by pleasure or sorrow and that these emotions can cause actions, became progressively part of a wider theory of animal and human behaviour. In the case of human behaviour, the "force of imagination" became a kind of general justification of all kind of anomic (...) and irregular behaviour and beliefs, including true paranormal conditions of the body. The book recapitulates the main evolution of this way of seeing passions - from Aristotle to Avicenna and his Latin followers - till the age of the authors who see the inner work of "imagination" as a constant danger for human reason, and imagination itself as faculty to control with care for its propension to be the "advocate" of the "inferior part of the soul", such as Gianfrancesco Pico, Juan Luis Vivés, Pierre Charron, Blaise Pascal and a large part of the French Augustinian Moral Philosophers. (shrink)

Explanations in behavioural neuroscience are often said to be mechanistic in the sense that they explain an organism’s behaviour by describing the activities and organisation of the organism’s parts that are “constitutively relevant” to organism behaviour. Much has been said about the constitutive relevance of working parts (in debates about the so-called “mutual manipulability criterion”), but relatively little has been said about the constitutive relevance of the organising relations between working parts. Some New Mechanists seem to endorse a simple causal-linking (...) account: organising relations are constitutively relevant to organism behaviour if and only if (and because) they are causal relations that link the working parts that are constitutively relevant to organism behaviour. In this paper, I argue that the causal-linking account is inadequate because it neglects the constitutive relevance of anatomical relations that organise the working parts of a behaving organism. I demonstrate this by considering a case study where the anatomical organisation of the barn owl (Tyto alba) is constitutively relevant to their mechanism for sound localization. The anatomical organisation of this mechanism is best understood as the back-and-forth flow of task information across 7 “levels of anatomy” (a notion that I distinguish from levels of mechanism). A further implication, I conclude, is that at least some of the interlevel structure of neuroscientific explanation is accounted for by levels of anatomy, not levels of mechanism. (shrink)

Este artículo tiene como propósito corroborar la cosmovisión de Octavio Paz, a partir de la inacción de la sociedad cotidiana, que es notoria en un fragmento del poema “Máscaras del alba” de La estación violenta (1958). Su crítica contra el sistema por la ausencia de compromiso social y político revela dos conceptos que fundamenta Mijaíl Bajtín en Estética de la creación verbal: su intencionalidad como autor y la expresión concomitante en función del género discursivo empleado. Para comprobar estas dos (...) premisas, incluiré como instrumento metodológico los campos figurativos o las provincias figurales que aborda Stefano Arduini, que comprenden los tropos de la metáfora, la metonimia, la sinécdoque, la metonimia, la elipsis, la antítesis y la repetición, además de sus variaciones. (shrink)

Este artículo tiene como objetivo confrontar la cosmovisión de Octavio Paz, desde la configuración ominosa que le atribuye al hombre y la sugerencia inferida por conllevar su tránsito óptimo de una suspensión o un truncamiento al dinamismo o la concretización de proyectos y utopías. Esa interpretación literaria se desarrolla de «Máscaras del alba» y «Repaso nocturno» de su poemario La estación violenta (1958). Para demostrar esa condensación autoral y comprender su intención, añado la epistemología de Stefano Arduini en función (...) de los campos figurativos que son de utilidad como sistema organizativo de los tropos y que se rigen de pensamientos metafórico, sinecdóquico, metonímico, elíptico, antitético y repetitivo, según cada caso. Esta taxonomía ha sido estudiada por el crítico Camilo Fernández Cozman, quien incorpora para un análisis más fructuoso la intervención de los interlocutores que participan en el discurso lírico. (shrink)

La crisi delle relazioni internazionali all'alba del XXI secolo e l'intreccio di politica e guerra per la salvaguardia dei poteri globali.

La presente compilación de textos es la segunda obra colectiva fruto del trabajo del grupo de investigadores que forman parte del proyecto La Alianza Bolivariana para las Américas (ALBA), sus políticas públicas y los valores fundacionales de la integración latinoamericana y caribeña, radicado en la Universidad Central «Marta Abreu» de Las Villas, Cuba. La temática abordada en esta obra (la evaluación de políticas públicas en América Latina) es continuidad lógica del primer libro de nuestro grupo de investigación, intitulado Políticas (...) públicas. Teoría y práctica en el escenario latinoamericano, publicado en 2018 bajo el sello de la Editorial Feijóo. En aquella obra se expuso una crítica constructiva al manejo de las políticas públicas por parte de los gobiernos progresistas instalados en el poder en América Latina en los tres primeros lustros del actual siglo. Consideramos constructiva la crítica realizada en aquel texto, pues la misma partió de un cuestionamiento a la teoría sobre política pública, a sus preceptos teóricos, al escaso arsenal sobre evaluación producido por los teóricos clásicos de esta materia, y particularmente a las interpretaciones y formas de aplicación de la política pública en todo el subcontinente americano, aun cuando el interés fundamental del proyecto eran los países del ALBA. Aunque el proyecto integracionista ALBA constituye nuestro objeto de estudio declarado, para los investigadores del grupo está claro que cualquier proceso de integración regional en América Latina solo se sostendrá si está cobijado por la unidad de los pueblos latinoamericanos y caribeños en torno a la defensa de su soberanía, identidad cultural y desarrollo autóctono. Respecto a ello, el memorable líder cubano Fidel Castro, en la Cumbre Iberoamericana de Salvador de Bahía, argumentó que: «La cuestión no estriba en que cada país de nuestra área trate de salvarse por sí mismo, porque es un sueño imposible en un mundo dominado hoy por gigantes industriales y políticos. Tenemos necesidad de crear entre todos un gigante, para poder realmente desarrollarnos y disfrutar de paz, independencia y seguridad». En vista de ello, casi desde el inicio del proceso investigativo nos inclinamos a ampliar nuestras indagaciones al resto de América Latina, lo que condujo a que en este texto (y muy probablemente en las entregas futuras sobre el tema de las políticas públicas en América Latina), aparecieran trabajos que no abordaban a los países que integran o integraron el ALBA-TCP, sino a otros países del subcontinente. La evaluación de políticas públicas en América Latina fue abordada desde varios ángulos y con distintos grados de profundidad, lo que generó diversos tipos de resultados. Algunos de estos no alcanzaron el nivel de coherencia requerido para su publicación inmediata, pero de igual forma fueron muy valiosos para el aprendizaje colectivo realizado en los talleres de discusión del proyecto, por lo que damos gracias a todos los esfuerzos e intentos realizados. Dado el escaso desarrollo sobre la cuestión de la evaluación de políticas públicas y especialmente el escaso desarrollo de este acápite en América Latina, no era posible pretender lograr evaluaciones rigurosas en un primer momento. Para el grupo de investigadores era esencial ganar en cultura de evaluación y hacer conciencia sobre este aspecto, que es el objetivo central de este libro. En vista de ello, el asunto de la evaluación de políticas públicas en América Latina se abordó desde el ámbito teórico general, enfatizando en su necesidad y rigurosidad, y desde experiencias concretas de evaluación en diversos países. En varios casos, estas experiencias no podemos identificarlas con evaluaciones propiamente dichas, sino con valoraciones o acercamientos a la evaluación, que contribuyen igualmente a elevar la cultura en este aspecto y a la conciencia de la necesidad de evaluación. (shrink)

RELAÇÃO E EFEITOS BIOQUÍMICO-NUTRICIONAIS SOBRE AS ALTERAÇÕES DO CORPO LÚTEO EM VACAS -/- Emanuel Isaque Cordeiro da Silva Departamento de Agropecuária – IFPE Campus Belo Jardim [email protected] ou [email protected] WhatsApp: (82)98143-8399 -/- •__7. ALTERAÇÕES DO CORPO LÚTEO -/- A estrutura funcional desenvolve-se a partir da cavidade folicular após a ovulação. O corpo lúteo é constituído pelas células da teca interna (pequenas e ativas na primeira fase do seu desenvolvimento) e células da granulosa (grandes e ativas na segunda metade do seu (...) desenvolvimento). As principais características de cada tipo de célula podem resumir-se da seguinte forma: As células pequenas são mais sensíveis à ação da LH porque possui uma quantidade maior de receptores biologicamente ativos para esta hormona e a resposta é mediada pelo sistema AMPc-adelinato ciclase. As grandes células lúteas têm menos receptores para a LH (a maior quantidade são para a PGF2α e a PGE2), e são as responsáveis pela produção da oxitocina luteal (BAH, et al. 2006; CAMPO, 2003). Contrariamente às pequenas células lúteas, a produção de progesterona (P4) é parcialmente controlada pelo sistema Ca+2 - Fosfatil inositol-quinase C (CAMPO, 2003). A regulação da função do corpo lúteo é um mecanismo complexo. Nela intervêm fatores tróficos e líticos que estão presentes em forma simultânea durante todo o ciclo estral, e portanto a estimulação ou inibição da síntese e secreção de P4 depende do balanço entre estes fatores. (CAMPO, 2003). Dentro dos fatores tróficos, os nutrientes desempenham um papel relevante sobre a luteólise e as funções luteotrópicas, entre estas pode-se citar a ação das seguintes: -/- 7.1 Vitaminas Deficiência em betacarotenos. Vitamina A é um termo genérico que designa qualquer composto com atividade de retinol, o trans-retinol, é o composto base, sua forma aldeído e ácido são chamados de retinol e ácido retinóico, respectivamente. Por outro lado, a forma ativa da Vitamina A participa no mecanismo da visão, como 11-cis-retinal. Adicionalmente, o betacaroteno, considerado uma provitamina A é a única forma em que esta encontra nas plantas. Em sentido nutricional, a família da Vitamina A compreende todos os compostos que possuem atividade de retinol, incluindo cerca de cinquenta carotenoides que possuem atividade de provitamina A, aceitando-se que o mais ativo é o trans-betacaroteno (TORRES, et al. 2002). As vitaminas que são necessárias para o crescimento e a produção, também são essenciais para a reprodução. As recomendações atuais de vitamina A são de 75.000 UI/dia durante a lactação e 80.000 UI/dia (nota: 1 mg de Vitamina A = 400 UI) durante o período seco nas vacas leiteiras. A suplementação com vitamina A tem pouco risco de toxicidade, enquanto a sua deficiência pode retardar o aparecimento do primeiro cio/estro, induzir cios/estros silenciosos, aumentar o número de quistos ováricos, reduzir os índices de concepção, causar abortos, mortes embrionárias e ocasionar o nascimento de bezerros debilitados e fracos, uma vez que não irão nascer com os índices e requerimentos ideais de nutrientes passados da mãe para o feto pela placenta, e que, já que a mãe possui deficiência nutricional, o colostro não terá o efeito completo para passar a imunidade essencial ao neonato. Embora os mecanismos de ação não sejam claros, foram notificadas maiores secreções de esteroides ováricos quando as concentrações de β-carotenos no fluido folicular foram elevadas; logo, foram observadas maiores concentrações elevadas de β- estradiol e vitamina A nos folículos que terminaram em ovulação do que naqueles que terminaram em atresia. Para evitar as perdas reprodutivas por deficiência de vitamina A, pode-se optar pela administração oral ou injetável desta ao animal, mediante dois métodos: o primeiro consiste em adicionar 1 a 2,5 kg de premix vitamínico em 1 tonelada de grãos o que supre de 4 a 6.000 UI o que é desejável; o segundo é a administração via injetável em quantidades vide bula do fármaco. 7.2 Minerais O excesso de fósforo é absorvido principalmente no intestino delgado dos mamíferos através de um mecanismo de transporte ativo dependente do sódio, que é estimulado pela pró-hormona 1,25- hidroxivitamina D3. Os ruminantes são capazes de absorver o fósforo dietético em proporção direta às quantidades presentes na ração. Estima-se que aproximadamente 1% do corpo animal é composto de fósforo, do qual 85% está presente nos dentes e no tecido ósseo. Os tecidos moles são capazes de conter entre 0,15-0,20% de fósforo sob a forma de fosfoproteínas, nucleoproteínas, fosfolipídios, fosfato creatinina, adenosintrifosfato, glicose-6-fosfato, etc. Ao nível do plasma sanguíneo, o fósforo apresenta valores de 12,09 mg/dl. Os valores plasmáticos de fósforo são regulados principalmente pelo rim, sendo observado um aumento na excreção urinária do elemento inorgânico quando este excede a capacidade de transporte (REBOLLAR & MATEOS, 1999). O fósforo faz parte dos fosfolipídios, que são importantes no transporte de lipídios e seu metabolismo, como componente das membranas celulares. O fosfato faz parte do RNA e do DNA, componentes celulares vitais, e são essenciais para a síntese proteica. O fosfato faz parte de sistemas enzimáticos como a cocarboxilase e NAD, portanto está envolvido em todos os processos de síntese e regulação energética, dado que o corpo lúteo requer altas quantidades de energia para a síntese celular e hormonal, um excesso de fósforo pode bloquear a capacidade renal da sua regulação gerando um desequilíbrio catiônico que descompensa a relação Na:K, já que deverão ser excretados íons fosfato para regular o equilíbrio ácido-básico, desta forma, os processos celulares em tecidos de alta sensibilidade como o ovário serão afetados em sua função. A situação para prevenção de problemas relacionados ao fósforo (P) já foi tratada em assuntos anteriores, porém, sempre vale frisar para o leitor fiel que me lê que as exigências de P presentes na matéria seca (MS) variam entre 0,17 e 0,59% de P por kg/MS para bovinos de corte e em 0,32 a 0,44% por kg/MS para o gado leiteiro. Dessa forma, dados obtidos por pesquisas, ditam que para a mantença de uma vaca ou quaisquer outra categoria bovina o ideal é o consumo de 1.43 g/100 kg de peso vivo (PV), garantindo assim a prevenção de possíveis afecções reprodutivas como as alterações do corpo lúteo. Gramíneas, forragens, leguminosas e os concentrados fornecem muito bem os requerimentos de fósforo para os animais, todavia deve-se estar atento as relações e dependências do P com outros elementos como o Ca e a relação Na:K (10-15:1 idealmente). 7.3 Compostos estrogênicos Os fitoestrogênios afetam repetidamente a estabilidade do corpo lúteo. Os compostos estrogênicos encontrados principalmente em leguminosas pertencem principalmente a três grupos: isoflavanos, isoflavonas, presentes no gênero Trifolium e praticamente restritos às leguminosas, e cumestanos, que foram estudados na alfafa (Medicago sativa) e na Melilotus alba. Todas as isoflavonas sofrem algum grau de transformação no rúmen, sendo o Isoflavonoide formononetina, na realidade um pró-estrógeno, o único que se ativa no ecossistema ruminal ao ser convertido em equol, enquanto que as demais são degradadas a produtos inativos (RAMOS, et al. 1998). Por fim, a alta concentração no sangue do equol retarda a retroalimentação sobre a hipófise mediante a qual se reduzem os níveis de FSH para dar lugar à onda ovulatória de LH, se esta não ocorrer, o corpo lúteo obviamente não se formará. O conhecimento acerca dos estrogênios na alimentação animal é defasado nos livros sobre o tema, no entanto, o criador pode ficar tranquilo no que tange o tema na prática da sua fazenda e dos seus animais, uma vez que tal elemento é muito bem fornecido naturalmente por meio dos alimentos volumosos presentes no seu pasto. -/- Apoio -/- Realização -/- REFERÊNCIAS BIBLIOGRÁFICAS BAH, Mamadou M. et al. Role of intraluteal prostaglandin F2α, progesterone and oxytocin in basal and pulsatile progesterone release from developing bovine corpus luteum. Prostaglandins & other lipid mediators, v. 79, n. 3-4, p. 218-229, 2006. BERCHIELLI, Telma Teresinha; PIRES, Alexandre Vaz; OLIVEIRA, SG de. Nutrição de ruminantes. Jaboticabal: funep, 2006. BINDARI, Yugal Raj et al. Effects of nutrition on reproduction-A review. Adv. Appl. Sci. Res, v. 4, n. 1, p. 421-429, 2013. BOLAND, M. P. Efectos nutricionales en la reproducción del ganado. XXXI Jornadas Uruguayas de Buiatría, 2003. CAMPO, E. Comportamiento reproductivo del ganado Bovino y Bufalino. 2003. Universidad Agraria de la Habana. Havana, 2003. DEHNING, R. Interrelaciones entre nutrición y fertilidad. In: Curso Manejo de la Fertilidad Bovina18-23 May 1987Medellín (Colombia). CICADEP, Bogotá (Colombia) Universidad de La Salle, Medellín (Colombia) Instituto Colombiano Agropecurio, Bogotá (Colombia) Sociedad Alemana de Cooperación Técnica-GTZ (Alemania), 1987. DE LUCA, Leonardo J. Nutrición y fertilidad en el ganado lechero. XXXVI Jornadas Uruguayas de Buiatría, 2008. FRAZER, Grant S. Bovine theriogenology. Veterinary Clinics: Food Animal Practice, v. 21, n. 2, p. xiii-xiv, 2005. GORDON, Ian. Controlled reproduction in farm animals series. Nova Iorque: CAB International, 1996. HURLEY, W. L.; DOANE, R. M. Recent developments in the roles of vitamins and minerals in reproduction. Journal of Dairy Science, v. 72, n. 3, p. 784-804, 1989. KUMAR, Sudhir et al. Importance of micro minerals in reproductive performance of livestock. Veterinary world, v. 4, n. 5, p. 230, 2011. MAAS, John. Relationship between nutrition and reproduction in beef cattle. The Veterinary Clinics of North America. Food Animal Practice, v. 3, n. 3, p. 633-646, 1987. PASA, Camila. Relação reprodução animal e os minerais. Biodiversidade, v. 9, n. 1, 2011. RAMOS, Graciano et al. Los compuestos secundarios de las plantas en la nutrición de los herbívoros. Archivos de Zootecnia. 47: 597-620, 1998. REBOLLAR, Paloma García; MATEOS, Gonzalo González. El fósforo en nutrición animal. Necesidades, valoración de materias primas y mejora de la disponibilidad. CURSO DE ESPECIALIZACIÓN FEDNA. Avances en nutrición y alimentaciín animal, XV, p. 19-64, 1999. SHORT, Robert E.; ADAMS, D. C. Nutritional and hormonal interrelationships in beef cattle reproduction. Canadian Journal of Animal Science, v. 68, n. 1, p. 29-39, 1988. TEIXEIRA, J. C.; TEIXEIRA, LFAC. Alimentação de bovinos leiteiros. FAEPE, Lavras, 1997. TEIXEIRA, J. C. Nutrição de ruminantes. Lavras: FAEPE, 1992. TORRES, M. et al. Aspectos Farmacológicos relevantes de las Vitaminas Antioxidantes (E, A y C). Archivos Venezolanos de Farmacología y Terapéutica, v. 21, n. 1, p. 22-27, 2002. YASOTHAI, R. Importance of minerals on reproduction in dairy cattle. International Journal of Science, Environment and Technology, v. 3, n. 6, p. 2051-2057, 2014. -/- Emanuel Isaque Cordeiro da Silva Belo Jardim, 29 de março de 2020. (shrink)

Kafka, il potere, la legge e noi. Il potere della legge e la legge del potere smascherati dalle opere e dalla vita di Kafka che diventano messaggero di verità e libertà. Proprio dal fondo più cupo dell'inferno in cui è stata inghiottita l'umanità, rinasce la speranza e la possibilità del vivere e amare. Kafka ci conduce sempre su quel finire della sera che ci accompagna alla nuova alba, dove tutto è sempre e nuovamente possibile.