Results for 'Post-trial access'

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  1. PostTrial Access to Antiretrovirals: Who Owes What to Whom?Joseph Millum - 2011 - Bioethics 25 (3):145-154.
    ABSTRACT Many recent articles argue that participants who seroconvert during HIV prevention trials deserve treatment when they develop AIDS, and there is a general consensus that the participants in HIV/aids treatment trials should have continuing posttrial access. As a result, the primary concern of many ethicists and activists has shifted from justifying an obligation to treat trial participants, to working out mechanisms through which treatment could be provided. In this paper I argue that this shift frequently (...)
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  2. Post-trial access to treatment: corporate best practices.Irene Schipper & Silvia Colona - 2015 - SOMO Centre for Research on Multinational Corporations.
    The paper Post-Trial Acces To Treatment (PTA) offers an insight into current corporate policies and corporate best practices relating to the provision of PTA in low and middle income countries based on company sources. In these countries there is a greater appeal for pharmaceutical companies to take responsibility for providing PTA. However, the practice of providing PTA is the exception rather than the rule.
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  3. MRCT Center Post-Trial Responsibilities Framework Continued Access to Investigational Medicines. Guidance Document. Version 1.0, December 2016.Carmen Aldinger, Barbara Bierer, Rebecca Li, Luann Van Campen, Mark Barnes, Eileen Bedell, Amanda Brown-Inz, Robin Gibbs, Deborah Henderson, Christopher Kabacinski, Laurie Letvak, Susan Manoff, Ignacio Mastroleo, Ellie Okada, Usharani Pingali, Wasana Prasitsuebsai, Hans Spiegel, Daniel Wang, Susan Briggs Watson & Marc Wilenzik - 2016 - The Multi-Regional Clinical Trials Center of the Brigham and Women’s Hospital and Harvard (MRCT Center).
    I. EXECUTIVE SUMMARY The MRCT Center Post-trial Responsibilities: Continued Access to an Investigational Medicine Framework outlines a case-based, principled, stakeholder approach to evaluate and guide ethical responsibilities to provide continued access to an investigational medicine at the conclusion of a patient’s participation in a clinical trial. The Post-trial Responsibilities (PTR) Framework includes this Guidance Document as well as the accompanying Toolkit. A 41-member international multi-stakeholder Workgroup convened by the Multi-Regional Clinical Trials Center of (...)
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  4. Posttrial obligations in the Declaration of Helsinki 2013: classification, reconstruction and interpretation.Ignacio Mastroleo - 2016 - Developing World Bioethics 16 (2):80-90.
    The general aim of this article is to give a critical interpretation of post-trial obligations towards individual research participants in the Declaration of Helsinki 2013. Transitioning research participants to the appropriate health care when a research study ends is a global problem. The publication of a new version of the Declaration of Helsinki is a great opportunity to discuss it. In my view, the Declaration of Helsinki 2013 identifies at least two clearly different types of post-trial (...)
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  5. Traducción de la Disposición 12792/2016 ANMAT: procedimiento para la solicitud de importación de la medicación/ tratamiento /materiales para el acceso post-estudio (selección, versión 1.0).Mastroleo Ignacio - manuscript
    Translation from Spanish to English of ANMAT’s procedure for import of post-trial access provisions. This is a regulatory mechanisim to comply with post-trial provisions requirement in Declaration of Helsinki, paragraph 34. The translation it is based on a selection of the text of ANMAT’s Provision 12792/2016. -/- .
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  6. EI principio de acceso posinvestigación en la revisión 2008 de la Declaración de Helsinki.Ignacio Mastroleo - 2008 - Perspectivas Bioéticas 13 (24-25):140-157.
    El objetivo del presente trabajo es analizar la nueva formulación del principio de acceso posinvestigación en la más reciente (2008) revisión de la Declaración de Helsinki. Se identifican los artículos relevantes de la Declaración y se presentan dos interpretaciones posibles del principio de acceso posinvestigación: una interpretación robusta y otra permisiva, inspiradas cada una por modelos de justicia distintos. Luego, se hace una evaluación crítica de dichas interpretaciones y se intenta avanzar argumentos en contra de la interpretación permisiva. [The objective (...)
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  7. Justicia global e investigación biomédica: La obligación post investigación hacia la comunidad anfitriona.Ignacio Mastroleo - 2007 - Perspectivas Bioéticas 12 (23):76-92.
    Este artículo considera el problema de justicia en la investigación biomédica en países en desarrollo. En particular se hace foco en la discusión de si el requisito de poner a disposición toda intervención probada efectiva puede ser considerado como una obligación post investigación de los patrocinadores hacia la comunidad anfitriona. Primero, se discuten las concepciones de la Comisión Nacional de Asesoramiento sobre Bioética (NBAC) de los Estados Unidos y de las guías éticas internacionales sobre la obligación post investigación (...)
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  8. Consideraciones sobre las obligaciones posinvestigación en la Declaración de Helsinki 2013.Ignacio Mastroleo - 2014 - Revista de Bioética y Derecho 31:51-65.
    El problema de la transición de los participantes desde una investigación hacia la atención de la salud apropiada es un problema global. La publicación de una nueva versión de la Declaración de Helsinki es una excelente oportunidad para repensar este problema. Según mi interpretación, la Declaración de Helsinki 2013 introduce dos tipos diferentes de obligaciones posinvestigación, a saber, (1) obligaciones de acceso a atención de la salud y (2) obligaciones de acceso a información. Los beneficiarios pretendidos de estas obligaciones son (...)
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  9. Introducción al problema de la continuidad del tratamiento beneficioso para los sujetos de investigación.Ignacio Mastroleo - 2015 - In Jorge Alberto Álvarez Díaz (ed.), Ensayos sobre ética de la salud. Universidad Autónoma Metropolitana - Unidad Xochimilco. pp. 67 - 99.
    ¿Qué ocurre con la continuidad del tratamiento de los sujetos de investigación después de que realizan la última visita del ensayo en el que participan? En algunos casos, la falta de continuidad de atención de la salud apropiada podría poner en peligro la salud de estas personas. Por lo tanto, es probable que los sujetos de investigación que al terminar su participación en un ensayo todavía se encuentran enfermos, necesiten continuar con el tratamiento en estudio u otra atención de la (...)
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  10. Atención después de la investigación: un marco para los comités de ética de investigación del National Health Service (NHS) (borrador versión 8.0).Neema Sofaer, Penny Lewis & Hugh Davies - 2012 - Perspectivas Bioéticas 17 (33):47-70.
    Resumen Ésta es la primera traducción al español de las guías “Atención después de la investigación: un marco para los comités de ética de investigación del National Health Service (NHS) (borrador versión 8.0)”. El documento afirma que existe una fuerte obligación moral de garantizar que los participantes enfermos de un estudio clínico hagan una transición después del estudio hacia una atención de la salud apropiada. Con “atención de la salud apropiada” se hace referencia al acceso para los participantes a la (...)
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  11. For the Common Good: Philosophical Foundations of Research Ethics.Alex John London - 2021 - New York, NY, USA: Oxford University Press.
    The foundations of research ethics are riven with fault lines emanating from a fear that if research is too closely connected to weighty social purposes an imperative to advance the common good through research will justify abrogating the rights and welfare of study participants. The result is an impoverished conception of the nature of research, an incomplete focus on actors who bear important moral responsibilities, and a system of ethics and oversight highly attuned to the dangers of research but largely (...)
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  12. La obligación de continuidad de tratamiento beneficioso hacia los sujetos de investigación.Ignacio Mastroleo - 2012 - Dissertation, Universidad de Buenos Aires
    Todos los días se prueban nuevos psicofármacos, tratamientos para el VIH/SIDA o el cáncer, entre otras enfermedades. Algunos de esos tratamientos son lo suficientemente exitosos como para cronificar enfermedades antes consideradas mortales, como los antirretrovirales para el VIH/SIDA o el imatinib para la leucemia mieloide a principios del 2000. No obstante, antes de que puedan ser comercializados o estar disponibles en los sistemas de salud pública, deben pasar por una serie de rigurosas pruebas de calidad, seguridad y eficacia. Estas pruebas (...)
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  13. Care after research: a framework for NHS RECs.Neema Sofaer, Penney Lewis & Hugh Davies - 2012 - Health Research Authority.
    Care after research is for participants after they have finished the study. Often it is NHS-provided healthcare for the medical condition that the study addresses. Sometimes it includes the study intervention, whether funded and supplied by the study sponsor, NHS or other party. The NHS has the primary responsibility for care after research. However, researchers are responsible at least for explaining and justifying what will happen to participants once they have finished. RECs are responsible for considering the arrangements. There are (...)
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  14. Guías para los comités de ética de investigación del Reino Unido sobre atención de la salud después de la investigación: un comentario crítico sobre la traducción al español del borrador versión 8.0.Ignacio Mastroleo - 2012 - Perspectivas Bioéticas 17 (33):71-81.
    Este trabajo es un comentario sobre la primera traducción al español de las guías del Reino Unido “Atención después de la investigación: un marco para los comités de ética de investigación del NHS (borrador versión 8.0)”. El comentario se divide en tres partes. En la primera parte, se busca resumir la información básica necesaria para mejorar la lectura comprensiva de la traducción de las guías. En la segunda parte, se analiza una selección de la normativa argentina que trata sobre atención (...)
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  15. Pandemic Ethics: 8 Big Questions of COVID-19.Ben Bramble - 2020 - Sydney: Bartleby Books.
    A clear and provocative introduction to the ethics of COVID-19, suitable for university-level students, academics, and policymakers, as well as the general reader. It is also an original contribution to the emerging literature on this important topic. The author has made it available Open Access, so that it can be downloaded and read for free by all those who are interested in these issues. Key features include: -/- A neat organisation of the ethical issues raised by the pandemic. An (...)
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  16. International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC). A new collaborative global platform for global clinical trials targeting post-COVID19 patients.Maria Izabel Cavalcante Siqueira - 2022 - Manual Therapy, Posturology and Rehabilitation Journal 20:1-6.
    Background: In response to the pandemic caused by COVID-19, World Health Organization (WHO), together with International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC), developed research protocols facilitating global collaboration and accelerating the understanding of the disease, to identify the potential symptoms and persistent sequelae in infected individuals, which can be used in different areas of health, that is, in primary care, at a hospital or outpatient level, both public and private. Objective: To describe the International Severe Acute Respiratory and (...)
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  17. A taxonomy of multinational ethical and methodological standards for clinical trials of therapeutic interventions.C. M. Ashton, N. P. Wray, A. F. Jarman, J. M. Kolman, D. M. Wenner & B. A. Brody - 2011 - Journal of Medical Ethics 37 (6):368-373.
    Background If trials of therapeutic interventions are to serve society's interests, they must be of high methodological quality and must satisfy moral commitments to human subjects. The authors set out to develop a clinical - trials compendium in which standards for the ethical treatment of human subjects are integrated with standards for research methods. Methods The authors rank-ordered the world's nations and chose the 31 with >700 active trials as of 24 July 2008. Governmental and other authoritative entities of the (...)
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  18. Bubbles and Chambers: Post-Truth and Belief Formation in Digital Social-Epistemic Environments.Massimiliano Badino - 2022
    It is often claimed that epistemic bubbles and echo chambers foster post-truth by filtering our access to information and manipulating our epistemic attitude. In this paper, I try to add a further level of analysis by adding the issue of belief formation. Building on cognitive psychology work, I argue for a dual-system theory according to which beliefs derive from a default system and a critical system. One produces beliefs in a quasi-automatic, effortless way, the other in a slow, (...)
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  19. Perceptual Consciousness and Cognitive Access from the Perspective of Capacity-Unlimited Working Memory.Steven Gross - forthcoming - Philosophical Transactions of the Royal Society B.
    Theories of consciousness divide over whether perceptual consciousness is rich or sparse in specific representational content and whether it requires cognitive access. These two issues are often treated in tandem because of a shared assumption that the representational capacity of cognitive access is fairly limited. Recent research on working memory challenges this shared assumption. This paper argues that abandoning the assumption undermines post-cue-based “overflow” arguments, according to which perceptual conscious is rich and does not require cognitive (...). Abandoning it also dissociates the rich/sparse debate from the access question. The paper then explores attempts to reformulate overflow theses in ways that don’t require the assumption of limited capacity. Finally, it discusses the problem of relating seemingly non-probabilistic perceptual consciousness to the probabilistic representations posited by the models that challenge conceptions of cognitive access as capacity-limited. (shrink)
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  20. Values for a Post-Pandemic Future.Matthew James Dennis, Georgy Ishmaev, Steven Umbrello & Jeroen van den Hoven (eds.) - 2022 - Cham: Springer.
    This Open Access book shows how value sensitive design (VSD), responsible innovation, and comprehensive engineering can guide the rapid development of technological responses to the COVID-19 crisis. Responding to the ethical challenges of data-driven technologies and other tools requires thinking about values in the context of a pandemic as well as in a post-COVID world. Instilling values must be prioritized from the beginning, not only in the emergency response to the pandemic, but in how to proceed with new (...)
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  21. Accessing Online Data for Youth Mental Health Research: Meeting the Ethical Challenges.Elvira Perez Vallejos, Ansgar Koene, Christopher James Carter, Daniel Hunt, Christopher Woodard, Lachlan Urquhart, Aislinn Bergin & Ramona Statache - 2019 - Philosophy and Technology 32 (1):87-110.
    This article addresses the general ethical issues of accessing online personal data for research purposes. The authors discuss the practical aspects of online research with a specific case study that illustrates the ethical challenges encountered when accessing data from Kooth, an online youth web-counselling service. This paper firstly highlights the relevance of a process-based approach to ethics when accessing highly sensitive data and then discusses the ethical considerations and potential challenges regarding the accessing of public data from Digital Mental Health (...)
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  22. Does Perceptual Consciousness Overflow Cognitive Access? The Challenge from Probabilistic, Hierarchical Processes.Steven Gross & Jonathan Flombaum - 2017 - Mind and Language 32 (3):358-391.
    Does perceptual consciousness require cognitive access? Ned Block argues that it does not. Central to his case are visual memory experiments that employ post-stimulus cueing—in particular, Sperling's classic partial report studies, change-detection work by Lamme and colleagues, and a recent paper by Bronfman and colleagues that exploits our perception of ‘gist’ properties. We argue contra Block that these experiments do not support his claim. Our reinterpretations differ from previous critics' in challenging as well a longstanding and common view (...)
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  23. Against Compassion: Post-traumatic Stories in Arendt, Benjamin, Melville, and Coleridge.Andrea Timár - 2023 - Arendt Studies 6:223-246.
    The paper suggests that Samuel Taylor Coleridge’s arguments against sympathy after the French Revolution, Walter Benjamin’s claims against empathy following the traumatic shock of Modernity and the First World War, and Hannah Arendt’s critical take on compassion. after the Holocaust are similar responses to singular historical crises. Reconsidering Arendt’s On Revolution (1963) and its evocation of Hermann Melville’s novella Billy Budd (1891), I show first that the novella bears the traces of an essay by Samuel Taylor Coleridge, “The Appeal to (...)
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  24. Eternity in Kant and Post-Kantian European Thought.Alistair Welchman - 2016 - In Yitzhak Y. Melamed (ed.), Eternity a History. New York, New York: Oxford University Press USA. pp. 179-225.
    The story of eternity is not as simple as a secularization narrative implies. Instead it follows something like the trajectory of reversal in Kant’s practical proof for the existence of god. In that proof, god emerges not as an object of theoretical investigation, but as a postulate required by our practical engagement with the world; so, similarly, the eternal is not just secularized out of existence, but becomes understood as an entailment of, and somehow imbricated in, the conditions of our (...)
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  25. Husserl, the Differend and Kafka's 'The Trial'.William Conklin - 1996 - Analecta Husserliana 49:115-125.
    Kafka’s The Trial describes how K slowly loses his familiar language. He does speak a language but his language becomes monologic towards others and the language of others becomes monologic towards K. There seems to be no other person who, in a private and professional life, can respond to K’s words and gestures in a manner which K can understand. The others embody their own meanings into K’s words. Such meanings only possess value within the discourses of self-styled legal (...)
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  26. Compassionate Exclusivism: Relational Atonement and Post-Mortem Salvation.Aaron Brian Davis - 2021 - Journal of Analytic Theology 9:158-179.
    Faithful persons tend to relate to their religious beliefs as truth claims, particularly inasmuch as their beliefs have soteriological implications for those of different religions. For Christians the particular claims which matter most in this regard are those made by Jesus of Nazareth and his claims are primarily relational in nature. I propose a model in which we understand divine grace from Jesus as being mediated through relational knowledge of him on a compassionately exclusivist basis, including post-mortem. Supporting this (...)
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  27. Van Gordon, W., Shonin, E., Dunn, T., Garcia-Campayo, J., & Griffiths, M. D. (2017). Meditation Awareness Training for the treatment of fibromyalgia: A randomised controlled trial. British Journal of Health Psychology, 22, 186-206.William Van Gordon, Edo Shonin, Thomas Dunn, Javier Garcia-Campayo & Mark Griffiths - 2017 - British Journal of Health Psychology 22:186-206.
    Objectives. The purpose of this study was to conduct the first randomized controlled trial (RCT) to evaluate the effectiveness of a second-generation mindfulness-based intervention (SG-MBI) for treating fibromyalgia syndrome (FMS). Compared to first generation mindfulness-based interventions, SG-MBIs are more acknowledging of the spiritual aspect of mindfulness. Design. A RCT employing intent-to-treat analysis. Methods. Adults with FMS received an 8-week SG-MBI known as meditation awareness training (MAT; n = 74) or an active control intervention known as cognitive behaviour theory for (...)
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  28. INFORMATION COMMUNICATION TECHNOLOGY IN THE ERA OF POST-TRUTH CHALLENGE: BEYOND LOGIC AND EPISTEMOLOGY.Alloy Ihuah - manuscript
    Human actions and decisions are most of the times not only grounded on emotional reactions, they are irrationally debasing. While such emotions and heuristics were perhaps suitable for dealing with life in the Stone Age, they are woefully inadequate in the Silicon Age. The substitution of traditional news agencies and communication platforms in Nigeria with social media networks has not only increased human capacities, it has aided the common good and further eased communication and increased the human knowledge base. For (...)
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  29. Digital Literacy and Digital Competence of Selected Filipino Teachers: Basis for a Post-Pandemic Pedagogy.Jhessie Abella & Elmer Dela Rosa - 2023 - Ijorer : International Journal of Recent Educational Research 4 (5):548-569.
    Objective: The study seeks to provide a thorough description of the teachers' digital literacy (DL) and digital competence (DC) and shine a light on the variables that influence the development of their digital literacies and competence. Method: Comprehensive data collection and analysis from 274 participants were completed. Descriptive and inferential statistics were conducted to accomplish the objectives of this study. Results: It came to light that teachers with less than ten years of experience have higher levels of digital literacy. Pre-service (...)
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  30. ImmPort, toward repurposing of open access immunological assay data for translational and clinical research.Sanchita Bhattacharya, Patrick Dunn, Cristel Thomas, Barry Smith, Henry Schaefer, Jieming Chen, Zicheng Hu, Kelly Zalocusky, Ravi Shankar & Shai Shen-Orr - 2018 - Scientific Data 5:180015.
    Immunology researchers are beginning to explore the possibilities of reproducibility, reuse and secondary analyses of immunology data. Open-access datasets are being applied in the validation of the methods used in the original studies, leveraging studies for meta-analysis, or generating new hypotheses. To promote these goals, the ImmPort data repository was created for the broader research community to explore the wide spectrum of clinical and basic research data and associated findings. The ImmPort ecosystem consists of four components–Private Data, Shared Data, (...)
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  31. Knowledge Sharing in Higher Institution: A Nigeria Post-Secondary Technical Institution Case Study.Emmanuel Ukpe - 2023 - Information and Knowledge Management 13 (1-7).
    In the ever-changing landscape of education, the integration of Information and Communication Technologies (ICT) has emerged as a transformative force, reshaping traditional teaching methods and enhancing learning experiences. This study delves into the complexities of ICT adoption in Nigerian higher education, focusing on post-secondary technical education programs or National Diploma and Higher National Diploma (ND/HND) awarding institutions. The significance of this study lies in addressing challenges faced by developing nations like Nigeria, where harnessing ICT-driven education could resolve pressing issues (...)
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  32. Embracing Change with All Four Arms: Post-Humanist Defense of Genetic Engineering.J. Hughes - 1996 - Eubios Journal of Asian and International Bioethics 6 (4):94-101.
    This paper sets out to defend human genetic engineering with a new bioethical approach, post-humanism, combined with a radical democratic political framework. Arguments for the restriction of human genetic engineering, and specifically germ-line enhancement, are reviewed. Arguments are divided into those which are fundamental matters of faith, or "bio-Luddite" arguments, and those which can be addressed through public policy, or "gene-angst" arguments.The four bio-Luddite concerns addressed are: Medicine Makes People Sick; There are Sacred Limits of the Natural Order; Technologies (...)
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  33. Individualism: Allowed Access.Alex V. Halapsis - 2018 - Politology Bulletin 80:35-45.
    The purpose of the article is to identified the origin and essence of Western individualism. Methods of research. I used the methodology of post-nonclassical metaphysics of history, as well as the methods of epistemological polytheism and comparative. Results. The first sprouts of individualism can be detected in Greek poleis. It is the crisis of the polis system in Ancient Greece that predetermined the disappointment of the Greeks in the old collectivist ideals. Roman collectivism quite naturally got along with ideas (...)
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  34. Macro-reasoning and cognitive gaps: understanding post-Soviet Russians’ communication styles.Elena Fell - 2017 - ESSACHESS 10 (1(19)):91-110.
    Russians and Westerners access, process and communicate information in different ways. Whilst Westerners favour detailed analysis of subject matter, Russians tend to focus on certain components that are, in their view, significant. This disparity makes it difficult to achieve constructive dialogues between Western and Russian stakeholders contributing to cross-cultural communication problems. The author claims that the difference in the ways Russians and Westerners negotiate information is a significant cultural difference between Russia and West rather than an irritating (and in (...)
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  35. Toward a Post-Kantian Constructivism.Jack Samuel - 2023 - Ergo: An Open Access Journal of Philosophy 9 (53):1449–1484.
    The conventional wisdom regarding the aims and shortcomings of Kantian constructivism is mistaken. The aim of metaethical constructivism is not to provide a naturalistic account of the objectivity of normative facts by deriving substantive morality from a conception of agency so thin as to be uncontroversial (a task at which it is generally regarded to have failed). Its aim is to explain the “grip” that normative facts have on us—to avoid what I call the problem of normative alienation. So understood, (...)
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  36. Government Surveillance and Why Defining Privacy Matters in a Post‐Snowden World.Kevin Macnish - 2016 - Journal of Applied Philosophy (2).
    There is a long-running debate as to whether privacy is a matter of control or access. This has become more important following revelations made by Edward Snowden in 2013 regarding the collection of vast swathes of data from the Internet by signals intelligence agencies such as NSA and GCHQ. The nature of this collection is such that if the control account is correct then there has been a significant invasion of people's privacy. If, though, the access account is (...)
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  37. Self-treatment of psychosis and complex post-traumatic stress disorder with LSD and DMT—A retrospective case study.Mika Turkia - 2022 - Psychiatry Research Case Reports 1 (2):100029.
    This article describes a case of a teenager with early complex trauma due to chronic domestic violence. Cannabis use triggered auditory hallucinations, after which the teenager was diagnosed with an acute schizophrenia-like psychotic disorder. Antipsychotic medication did not fully resolve symptoms. Eventually the teenager chose to self-medicate with LSD in order to resolve a suicidal condition. The teenager carried out six unsupervised LSD sessions, followed by an extended period of almost daily use of inhaled low-dose DMT. Psychotic symptoms were mostly (...)
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  38. SOCIAL MEDIA AND RELIGIOSITY A (POST)PHENOMENOLOGICAL ACCOUNT.Ehsan Arzroomchilar - 2022 - Journal for the Study of Religions and Ideologies 21 (63).
    As access to the internet continues to grow, so do concerns about its effects on individuals. This digital revolution is not without its religious implications, and it appears that opinions are divided on how religiosity is being affected. On the one hand, it is possible that the emergence of virtual Islam could lead to an increase in extremism. On the other hand, with more exposure to diverse perspectives, religious tolerance may be bolstered. This article examines the potential effects of (...)
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  39. The Province of Conceptual Reason: Hegel's Post-Kantian Rationalism.William Clark Wolf - unknown
    In this dissertation, I seek to explain G.W.F. Hegel’s view that human accessible conceptual content can provide knowledge about the nature or essence of things. I call this view “Conceptual Transparency.” It finds its historical antecedent in the views of eighteenth century German rationalists, which were strongly criticized by Immanuel Kant. I argue that Hegel explains Conceptual Transparency in such a way that preserves many implications of German rationalism, but in a form that is largely compatible with Kant’s criticisms of (...)
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  40. Electrical analysis of logical complexity: Brain Informatics Open Access an exploratory eeg study of logically valid/ invalid deducive inference.Salto Francisco, Requena Carmen, Rodríguez Víctor, Poza Jesús & Hornero Roberto - 2023 - Brain Informatics 10 (13):1-15.
    Abstract Introduction Logically valid deductive arguments are clear examples of abstract recursive computational proce‐ dures on propositions or on probabilities. However, it is not known if the cortical time‐consuming inferential pro‐ cesses in which logical arguments are eventually realized in the brain are in fact physically different from other kinds of inferential processes. Methods In order to determine whether an electrical EEG discernible pattern of logical deduction exists or not, a new experimental paradigm is proposed contrasting logically valid and invalid (...)
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  41. Occipital and left temporal instantaneous amplitude and frequency oscillations correlated with access and phenomenal consciousness.Vitor Manuel Dinis Pereira - manuscript
    Given the hard problem of consciousness, there are no brain electrophysiological correlates of the subjective experience (the felt quality of redness or the redness of red, the experience of dark and light, the quality of depth in a visual field, the sound of a clarinet, the smell of mothball, bodily sensations from pains to orgasms, mental images that are conjured up internally, the felt quality of emotion, the experience of a stream of conscious thought, or the phenomenology of thought). However, (...)
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  42. Public Policy Experiments without Equipoise: When is Randomization Fair?Douglas MacKay & Emma Cohn - 2023 - Ethics and Human Research 45 (1):15-28.
    Government agencies and nonprofit organizations have increasingly turned to randomized controlled trials (RCTs) to evaluate public policy interventions. Random assignment is widely understood to be fair when there is equipoise; however, some scholars and practitioners argue that random assignment is also permissible when an intervention is reasonably expected to be superior to other trial arms. For example, some argue that random assignment to such an intervention is fair when the intervention is scarce, for it is sometimes fair to use (...)
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  43. Effectiveness of Enhanced Basic Education Information System (EBEIS)/ Learner Information System (LIS)Data and School Management.Alven Lopez & Rufino Lorejo - 2023 - International Journal of Interdisciplinary Organizational Studies 18 (1):689-707.
    Accessing reliable and accurate information is essential to the proliferation of information through various channels. This can help individuals make informed decisions and avoid misinformation or disinformation. In such a case, creating an online information system should be prioritized to provide available data and information for planning, budgeting, and allocating resources and operational targets. This study assessed the level of satisfaction with the usability of EBEIS/LIS data and school management by the Department of Education among public secondary schools of the (...)
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  44. Rising of Retracted Research Works and Challenges in Information Systems: Need New Features for Information Retrieval and Interactions.Peiling Wang - 2023 - In CHIIR '23: Proceedings of the 2023 Conference on Human Information Interaction and Retrieval. New York, USA: ACM. pp. 69-82.
    This perspective paper analyzes the rising threat of retracted scientific works and the challenges of preventing the continued spreading and use of the retracted science; further, a framework is proposed for research and actions to effectively manage retractions in the information ecosystem. The precipitous increase in retractions of scientific publications is real and the complexity of retracting publications challenges current IR systems and people's information behaviors. Retracting published, especially peer-reviewed, papers in prestigious venues is a complex phenomenon involving various entities (...)
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  45. Hollow Hunt for Harms.Jacob Stegenga - 2016 - Perspectives on Science 24 (5):481-504.
    Harms of medical interventions are systematically underestimated in clinical research. Numerous factors—conceptual, methodological, and social—contribute to this underestimation. I articulate the depth of such underestimation by describing these factors at the various stages of clinical research. Before any evidence is gathered, the ways harms are operationalized in clinical research contributes to their underestimation. Medical interventions are first tested in phase 1 ‘first in human’ trials, but evidence from these trials is rarely published, despite the fact that such trials provide the (...)
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  46. _Attention what is it like [Dataset].Vitor Manuel Dinis Pereira - manuscript
    R Core Team. (2016). R: A language and environment for statistical computing. R Foundation for Statistical Computing. Supplement to Occipital and left temporal instantaneous amplitude and frequency oscillations correlated with access and phenomenal consciousness. Occipital and left temporal instantaneous amplitude and frequency oscillations correlated with access and phenomenal consciousness move from the features of the ERP characterized in Occipital and Left Temporal EEG Correlates of Phenomenal Consciousness (Pereira, 2015) towards the instantaneous amplitude and frequency of event-related changes correlated (...)
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  47. Flaming Misogyny or Blindly Zealous Enforcement? The Bizarre Case of R v George.Lucinda Vandervort - 2019 - Manitoba Law Journal 42 (3):1-38.
    This article examines the distinction between judicial reasoning flawed by errors on questions of law, properly addressed on appeal, and errors that constitute judicial misconduct and are grounds for removal from the bench. Examples analysed are from the transcripts and reasons for decision in R v George SKQB (2015), appealed to the Saskatchewan Court of Appeal (2016) and the Supreme Court of Canada (2017), and from the sentencing decision rendered by the same judge more than a decade earlier in R (...)
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  48. Why Experimental Balance is Still a Reason to Randomize.David Teira & Marco Martinez - forthcoming - The British Journal for the Philosophy of Science.
    Experimental balance is usually understood as the control for the value of the conditions, other than the one under study, which are liable to affect the result of a test. We will discuss three different approaches to balance. ‘Millean balance’ requires to identify and equalize ex ante the value of these conditions in order to conduct solid causal inferences. ‘Fisherian balance’ measures ex post the influence of uncontrolled conditions through the analysis of variance. In ‘efficiency balance’ the value of (...)
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  49. Gandhi's Philosophy of Nonviolence: Essential Selections.Brian C. Barnett - manuscript
    A concise open-access textbook intended for an undergraduate audience, which brings together essential selections from Gandhi on nonviolence with supplementary materials, including: a preface; boxes providing examples, historical notes, extended explanations, and related philosophical work; overviews of post-Gandhian developments in nonviolence; diagrams, tables, and photos; discussion questions; reading and viewing suggestions; and a glossary.
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  50. Mad Speculation and Absolute Inhumanism: Lovecraft, Ligotti, and the Weirding of Philosophy.Ben Woodard - 2011 - Continent 1 (1):3-13.
    continent. 1.1 : 3-13. / 0/ – Introduction I want to propose, as a trajectory into the philosophically weird, an absurd theoretical claim and pursue it, or perhaps more accurately, construct it as I point to it, collecting the ground work behind me like the Perpetual Train from China Mieville's Iron Council which puts down track as it moves reclaiming it along the way. The strange trajectory is the following: Kant's critical philosophy and much of continental philosophy which has followed, (...)
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