Resident microbiota do not just shape host immunity, they can also contribute to host protection against pathogens and infectious diseases. Previous reviews of the protective roles of the microbiota have focused exclusively on colonization resistance localized within a microenvironment. This review shows that the protection against pathogens also involves the mitigation of pathogenic impact without eliminating the pathogens (i.e., “disease tolerance”) and the containment of microorganisms to prevent pathogenic spread. Protective microorganisms can have an impact beyond their niche, interfering with (...) the entry, establishment, growth, and spread of pathogenic microorganisms. More fundamentally, we propose a series of conceptual clarifications in support of the idea of a “co-immunity,” where an organism is protected by both its own immune system and components of its microbiota. -/- . (shrink)

The critique of the dogmatism of a-priorism from the Popperians suffered from the fact that Popper, too, was moving towards a certain dogmatic derivation. According to the a-priorists, in wanting to protect himself from any would-be-critics who would argue against the dogmatism of his approach, Popper left his philosophical foundation free to the critics. In fighting against German essentialism, he found himself in a position that necessitated the abandonment of either his presupposed anti-essentialism, or his critique of the positivists. Popper's (...) success stems less from his ability to rally the anti-historicist positivists towards the search for scientific foundations, than the fact that he was one of the greatest, if not the greatest, theoreticians of the scientific method, and critic of ideological simplicity. (shrink)

A new book by Klaus Schwab and Thierry Malleret, "COVID-19: The Great Reset", is reviewed. COVID-19 not only exacerbates social, economic, environmental, cultural and technological trends that already existed pre-pandemic, but also come with emergent and novel ones that may need to be pushed in certain directions to ensure that the fragilities of the pre-pandemic world do not manifest themselves in the future. This book is intended to provide a map of the various arguments and trends of how COVID-19 (...) has ‘reset’ most, if not all, sectors. Building robust and resilient systems of governance and living while avoiding the pitfalls of returning to how things were requires imagining how to direct these resets to more sustainable and green futures. The authors suggest radical, yet ambiguous ways to achieve these goals that may ultimately undermine them. (shrink)

Proceeding on the Automatic Deduction System developped at the Philosophy Faculty of the UNAM at Mexico City. (Deduktor Mexican Group of Logics work under the direction of the professor Hugo Padilla Chacón). Conference presented at the mexican City of Guadalajara at the Universidad de Guadalajara, Jalisco, by invitation of the latinoamerican association of philosophy SOPHIA. Early stage of the deductional systems at 2-valued logic. This work embodies the implementation of the first whole and standalone arithmetization of bivalent Logic, the theoretical (...) framework of Hugo Padilla Chacón published in 1984. (shrink)

Proceeding of the first public presentation of the work of the mexican logical group "Deduktor" under the direction of the mexican professor Hugo Padilla Chacón. This work was in fact the first whole and stand alone arithmetization of logics.

Proceeding of the work in trivalent logic developped under the direction of the professor Hugo Padilla Chacón at the 90's at the National Autonome University of México. Program in RLisp.

This is an English translation of my essay: Alfred Gierer Wissenschaft, Religion und die deutungsoffenen Grundfragen der Biologie. Mpi for the History of Science, preprint 388, 1-21, also in philpapers. Range and limits of science are given by the universal validity of physical laws, and by intrinsic limitations, especially in self-referential contexts. In particular, neurobiology should not be expected to provide a full understanding of consciousness and the mind. Science cannot provide, by itself, an unambiguous interpretation of the natural order (...) at the philosophical, cultural and religious level. The diversity of interpretations, however appears as a positive factor of cultural dynamics. Historically, the revival of the philosophy of nature in the middle ages included remarkable biological thoughts such as those of Eriugena and Thierry of Chartres. In this essay, emphasis is placed on basic issues of modern biology – the distinction of man and animal, the evolution of human mental capabilities, the physics of the universe as precondition for biological evolution, and the intricasies of the brain-mind-relation. They are open to agnostic as well as religious interpretations, the individual choice being mainly a matter of wisdom and not just of knowledge. -/-. (shrink)

From a behaviorist perspective, the desire to upload “minds” is already being realized on a mass, hyper-industrial scale thanks to the convergence of cognitive computing and Big Data. The accusation is that the “mind” is not an entity that exists intracranially. Instead, it is conceived as a process of individuation, which occurs in different modes and numbers. Some narratives of mind-uploading and technics in popular culture are explored: Transcendence (2014, dir. Wally Pfister) and Player Piano by Kurt Vonnegut. The discussed (...) issues consider Bernard Stiegler’s phenomenological notion of originary default and Thierry Bardini’s analysis of junk. Several questions are raised regarding miscalculations, accidents, in addition to Nicolas Agar’s discussion on the end of humanity, and Daniel Dennett’s Multiple Drafts theory within the context of exteriorization, which is considered as constitutive of interiority. (shrink)

The full text of this essay is available in an English translation (also in philpapers) under: Alfred Gierer, Science, religion, and basic biological issues that are open to interpretation. Der Artikel bildet das Schlusskapitel des Buches " Alfred Gierer: Wissenschaftliches Denken, das Rätsel Bewusstsein und pro-religiöse Ideen", Königshausen&Neumann, Würzburg 2019. Reichweite und Grenzen naturwissenschaftlicher Erklärungen ergeben sich zum einen aus der universellen Gültigkeit physikalischer Gesetze, zum anderen aus prinzipiellen, intrinsischen Grenzen der Bestimmbarkeit und Berechenbarkeit, zumal bei selbstbezüglichen Fragestellungen. In diesem (...) Essay geht es um deutungsoffene Grundfragen in Zusammenhang mit der Beziehung von Wissenschaft und Religion: Der Unterscheidung von Tier und Mensch, der Entstehung der mentalen Fähigkeiten der biologischen Spezies „Mensch“, den naturgesetzlichen Voraussetzungen eines „lebensfreundlichen“ physikalischen Universums, und der Reichweite wie den Grenzen einer naturwissenschaftlichen Erklärung von menschlichem Bewusstsein. Naturwissenschaft kann auf der philosophischen, kulturellen und religiösen Ebene die Mehrdeutigkeit der Welt nicht auflösen. Agnostische und religiöse Grundauffassungen werden auf Dauer ko-existieren, und die Wahl ist nicht nur eine Frage des Wissens, sondern besonders auch der Weisheit und der Lebenskunst. (shrink)