Results for 'embryonic stem cells'

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  1. Ethics Surrounding Human Embryonic Stem Cell Research.Joseph Nkang Ogar - 2019 - International Social Mentality and Researcher Thinkers Journal 5 (22).
    Since their discovery in the early 1990s, Stem Cell has brought the prospect of radically improving treatments for a host of diseases such as Alzheimer's, Parkinson's disease, cancers and many among other diseases that currently render patients and scientists helpless to combat. With the advent of medical and scientific research, comes the inevitable emergence of ethical controversy that often accompanied major scientific and medical development. The use of Stem Cell is no different. Those who seek to curtail the (...)
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  2. Stem Cell Research on Embryonic Persons Is Just.Aaron Rizzieri - 2012 - Journal of Bioethical Inquiry 9 (2):195-203.
    I argue that embryonic stem cell research is fair to the embryo, even on the assumption that the embryo has attained full personhood and an attendant right to life at conception. This is because the only feasible alternatives open to the embryo are to exist briefly in an unconscious state and be killed or to not exist at all. Hence, one is neither depriving the embryo of an enduring life it would otherwise have had nor is one causing (...)
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  3. The global HLA banking of embryonic stem cells requires further scientific justification.Zubin Master & Bryn Williams-Jones - 2007 - American Journal of Bioethics 7 (8):45-46.
    There is a widely acknowledged shortage of and an increasing demand for transplantable human organs and tissues (e.g., kidney, heart, lung, liver, cornea) in developed and developing countries around the world. In response to this need, Lott and Savulescu (2007) propose the creation of a human embryonic stem (hESC) bank to facilitate the equitable and efficient dissemination of human leukocyte anti- gen (HLA) matched tissues and organs to patients in need of replacement. Although not an unreasonable proposal, the (...)
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  4. Stemming the tide of normalisation: An expanded feminist analysis of the ethics and social impact of embryonic stem cell research.Shelley Tremain - 2006 - Journal of Bioethical Inquiry 3 (1-2):33-42.
    Feminists have indicated the inadequacies of bioethical debates about human embryonic stem cell research, which have for the most part revolved around concerns about the moral status of the human embryo. Feminists have argued, for instance, that inquiry concerning the ethics and politics of human embryonic stem cell research should consider the relations of social power in which the research is embedded. My argument is that this feminist work on stem cells is itself inadequate, (...)
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  5. Biopower, Styles of Reasoning, and What's Still Missing from the Stem Cell Debates.Shelley Tremain - 2010 - Hypatia 25 (3):577 - 609.
    Until now, philosophical debate about human embryonic stem cell (hESC) research has largely been limited to its ethical dimensions and implications. Although the importance and urgency of these ethical debates should not be underestimated, the almost undivided attention that mainstream and feminist philosophers have paid to the ethical dimensions of hESC research suggests that the only philosophically interesting questions and concerns about it are by and large ethical in nature. My argument goes some distance to challenge the assumption (...)
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  6. Direct Reprogramming and Ethics in Stem Cell Research.W. Malcolm Byrnes - 2008 - The National Catholic Bioethics Quarterly 8 (2):277-290.
    The recent successful conversion of adult cells into induced pluripotent stem (iPS) cells through direct reprogramming opens a new chapter in the study of disease and the development of regenerative medicine. It also provides a historic opportunity to turn away from the ethically problematic use of embryonic stem cells isolated through the destruction of human embryos. Moreover, because iPS cells are patient specific, they render therapeutic cloning unnecessary. To maximize therapeutic benefit, adult (...) cell research will need to be pursued in parallel with studies using iPS cells. Among the four alternative methods presented by the President’s Council on Bioethics, direct reprogram- ming is the most ethically acceptable. Nonetheless, iPS cells are tainted by their association with the human embryonic stem cell lines, derived in the past, which will be required for their validation. This concern is one that can be resolved. Human iPS cells will serve to stem the tide of human embryonic stem cell research, changing it and diverting stem cell research in a more ethical direction. (shrink)
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  7. The Lady Vanishes: What’s Missing from the Stem Cell Debate.Donna L. Dickenson - 2006 - Journal of Bioethical Inquiry 3 (1):43-54.
    Most opponents of somatic cell nuclear transfer and embryonic stem cell technologies base their arguments on the twin assertions that the embryo is either a human being or a potential human being, and that it is wrong to destroy a human being or potential human being in order to produce stem cell lines. Proponents’ justifications of stem cell research are more varied, but not enough to escape the charge of obsession with the status of the embryo. (...)
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  8. The philosophy of stem cells: Melinda Bonnie Fagan: Philosophy of stem cell biology: Knowledge in flesh and blood. Basingstoke and New York: Palgrave Macmillan, 2013, xx+274pp, £66.00 HB. [REVIEW]Stavros Ioannidis - 2015 - Metascience 24 (2):285-288.
    Melinda Fagan’s book on the philosophy of stem cell biology is a superb discussion of this exciting field of contemporary science, and the first book-length philosophical treatment of the subject. It contains a detailed and insightful examination of stem cell science, its structure, methods, and challenges.The book does not require any previous knowledge of stem cell biology—all the relevant scientific details and concepts, the central experimental procedures and results, as well as the historical development of the field, (...)
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  9. ANT-OAR Fails on All Counts: Method of Harvesting Stem Cells Riddled with Scientific and Ethical Flaws.W. Malcolm Byrnes & Jose Granados - 2006 - Science and Theology News (1):23-25.
    The altered nuclear transfer-oocyte assisted reprogramming (ANT-OAR) proposal has serious scientific and philosophical flaws, and it is not a morally acceptable means of obtaining embryonic stem cells. Note that this is the final preprint of an article that was published in the newspaper Science and Theology News in June 2006.
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  10. Comments on “Moral Complicity in Induced Pluripotent Stem Cell Research”.Byrnes W. Malcolm & J. Furton Edward - 2009 - Kennedy Institute of Ethics Journal 19 (2):202-205.
    In lieu of an abstract, here is a brief excerpt of the content:Comments on “Moral Complicity in Induced Pluripotent Stem Cell Research”W. Malcolm Byrnes, Ph.D. and Edward J. FurtonIn his article titled “Moral Complicity in Induced Pluripotent Stem Cell Research,” Mark T. Brown (2009) unfortunately mischaracterizes my ethical analysis of the use of induced pluripotent stem (iPS) cells for replacement therapies, or treatments (Byrnes 2008). In my paper, which Brown cites, I argue that, just as it (...)
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  11. Confessions of a" pro-life" Obama supporter.W. Malcolm Byrnes - 2009 - The National Catholic Bioethics Quarterly 9 (2):241-244.
    The author supported Barack Obama for president, and he agrees with Obama on most issues. However, he opposes the federal funding of human embryonic stem cell (hESC) research. Besides involving the destruction of human life, hESC research can (1) result in the exploitation of women, and (2) cause human reproduction to become a means to an end, i.e., human embryos will become commodities to be bought and sold. Recent scientific developments show the growing potential of induced pluripotent (...) (iPS) cells and the diminishing promise of their embryonic counterparts. When President Obama lifted restrictions on hESC research on March 9, 2009, he missed an opportunity to show moral leadership on a politically controversial issue. (shrink)
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  12. Who owns embryonic and fetal tissue?Donna Dickenson - 2002 - In Ethical Issues in Maternal-Fetal Medicine. Cambridge University Press. pp. 233-244.
    Until very recently the question of who owns embryonic or fetal tissue was of limited importance to clinicians, but advances in stem cell research have made such tissue commercially valuable. This chapter examines the legal and ethical basis of claims to property in embryonic or fetal tissue, taking a critical stance.
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  13. In dubio pro embryone. Neue Argumente zum moralischen Status menschlicher Embryonen.Gregor Damschen & Dieter Schönecker - 2003 - In Gregor Damschen & Dieter Schönecker (eds.), Der moralische Status menschlicher Embryonen. Pro und contra Spezies-, Kontinuums-, Identitäts- und Potentiali­tätsargument. Berlin & New York: de Gruyter. pp. 187-267.
    When in doubt, for the embryo. New arguments on the moral status of human embryos. - In the first part of our essay we distinguish the philosophical from the legal and political level of the embryo debate and describe our indirect justification strategy. It consists in renouncing a determination of the dignity-giving φ-properties and instead starting from premises that are undoubted by all discussion partners. In the second part we reconstruct and criticize the species, continuum, identity and potentiality arguments. The (...)
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  14. The Flawed Scientific Basis of the Altered Nuclear Transfer-Oocyte Assisted Reprogramming (ANT-OAR) Proposal.W. Malcolm Byrnes - 2007 - Stem Cell Reviews and Reports 1 (3):60-65.
    First put forth in June 2005, the altered nuclear transfer-oocyte assisted reprogramming (ANT-OAR) proposal has been promoted as an ethically-acceptable alternative to the embryo-destructive methods now used to obtain embryonic stem cells. According to its proponents, the goal of ANT-OAR is to use the cloning process to create a pluripotent stem cell. This would be achieved through overexpression of the transcription factor Nanog (or a hypothetical substitute) both in the enucleated egg cell and in the somatic (...)
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  15. Multiplex parenting: IVG and the generations to come.César Palacios-González, John Harris & Giuseppe Testa - 2014 - Journal of Medical Ethics 40 (11):752-758.
    Recent breakthroughs in stem cell differentiation and reprogramming suggest that functional human gametes could soon be created in vitro. While the ethical debate on the uses of in vitro generated gametes (IVG) was originally constrained by the fact that they could be derived only from embryonic stem cell lines, the advent of somatic cell reprogramming, with the possibility to easily derive human induced pluripotent stem cells from any individual, affords now a major leap in the (...)
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  16. Why human "altered nuclear transfer" is unethical: a holistic systems view.W. Malcolm Byrnes - 2005 - The National Catholic Bioethics Quarterly 5 (2):271-279.
    A remarkable event occurred at the December 3, 2004, meeting of the U. S. President’s Council on Bioethics. Council member William Hurlbut, a physician and Consulting Professor in the Program in Human Biology at Stanford University, formally unveiled a proposal that he claimed would solve the ethical problems surrounding the extraction of stem cells from human embryos. The proposal would involve the creation of genetically defective embryos that “never rise to the level of integrated organismal existence essential to (...)
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  17. Metaphysical and Moral Status of Cryopreserved Embryos.Jason T. Eberl - 2012 - The Linacre Quarterly 79 (3):304-315.
    Those who oppose human embryonic stem cell research argue for a clear position on the metaphysical and moral status of human embryos. This position does not differ whether the embryo is present inside its mother’s reproductive tract or in a cryopreservation tank. It is worth examining, however, whether an embryo in “suspended animation” has the same status as one actively developing in utero. I will explore this question from the perspective of Thomas Aquinas’s metaphysical account of human nature. (...)
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  18. “More on respect for embryos and potentiality: Does respect for embryos entail respect for in vitro embryos?”.Stephen S. Hanson - 2006 - Theoretical Medicine and Bioethics 27 (3):215-226.
    It is commonly assumed that persons who hold abortions to be generally impermissible must, for the same reasons, be opposed to embryonic stem cell research [ESR]. Yet a settled position against abortion does not necessarily direct one to reject that research. The difference in potentiality between the embryos used in ESR and embryos discussed in the abortion debate can make ESR acceptable even if one holds that abortion is impermissible. With regard to their potentiality, in vitro embryos are (...)
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  19. Pemanfaatan Sel Punca Embrionik dalam Pengembangan Bioteknologi Menurut Pandangan Hukum Islam.Moch Najib Yuliantoro - 2017 - In Yuliantoro Moch Najib (ed.), 9 Studi Kasus Hukum Islam Kontemporer. Pondok Pesantren Universitas Islam Indonesia. pp. 2-20.
    Pemanfaatan sel punca embrionik (Embryonic Stem Cells/ESCs) telah menjadi isu global dalam bidang bioteknologi modern yang selalu memicu perdebatan mendalam dari berbagai ilmuwan, filosof, agamawan, ahli hukum dan praktisi politik. Penelitian ini membahas gambaran umum dan manfaat sel punca embrionik, serta menganalisisnya berdasarkan pandangan hukum Islam. Metode yang digunakan adalah studi pustaka multidisiplin dari teks-teks ilmu medis, etika dan hukum Islam. Hasil penelitian ini menunjukkan bahwa meskipun masih terdapat perbedaan pandangan dari para ahli hukum Islam tentang kapan (...)
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  20. Thomistic Principles and Bioethics.Jason T. Eberl - 2006 - New York: Routledge.
    Alongside a revival of interest in Thomism in philosophy, scholars have realised its relevance when addressing certain contemporary issues in bioethics. This book offers a rigorous interpretation of Aquinas's metaphysics and ethical thought, and highlights its significance to questions in bioethics. Jason T. Eberl applies Aquinas’s views on the seminal topics of human nature and morality to key questions in bioethics at the margins of human life – questions which are currently contested in the academia, politics and the media such (...)
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  21. The epistemic costs of compromise in bioethics.Katrien Devolder & Thomas Douglas - 2017 - Bioethics 32 (2):111-118.
    Bioethicists sometimes defend compromise positions, particularly when they enter debates on applied topics that have traditionally been highly polarised, such as those regarding abortion, euthanasia and embryonic stem cell research. However, defending compromise positions is often regarded with a degree of disdain. Many are intuitively attracted to the view that it is almost always problematic to defend compromise positions, in the sense that we have a significant moral reason not to do so. In this paper, we consider whether (...)
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  22. Making matters of fraud: Sociomaterial technology in the case of Hwang and Schatten.Buhm Soon Park - 2020 - History of Science 58 (4):393-416.
    This paper revisits the “Hwang case,” which shook Korean society and the world of stem cell research in 2005 with the fraudulent claim of creating patient-specific embryonic stem cells. My goal is to overcome a human-centered, Korea-oriented narrative, by illustrating how materials can have an integral role in the construction and judgment of fraud. To this end, I pay attention to Woo Suk Hwang’s lab at Seoul National University as a whole, including human and nonhuman agents, (...)
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  23. Habermas and the Question of Bioethics.Hille Haker - 2019 - European Journal for Philosophy of Religion 11 (4):61-86.
    In The Future of Human Nature, Jürgen Habermas raises the question of whether the embryonic genetic diagnosis and genetic modification threatens the foundations of the species ethics that underlies current understandings of morality. While morality, in the normative sense, is based on moral interactions enabling communicative action, justification, and reciprocal respect, the reification involved in the new technologies may preclude individuals to uphold a sense of the undisposability of human life and the inviolability of human beings that is necessary (...)
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  24. Finding a consensus between philosophy of applied and social sciences: A case of biology of human rights.Ammar Younas - 2020 - JournalNX 6 (2):62 - 75.
    This paper is an attempt to provide an adequate theoretical framework to understand the biological basis of human rights. We argue that the skepticism about human rights is increasing especially among the most rational, innovative and productive community of intellectuals belonging to the applied sciences. By using examples of embryonic stem cell research, a clash between applied scientists and legal scientists cum human rights activists has been highlighted. After an extensive literature review, this paper concludes that the advances (...)
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  25. Social Darwinism, Eugenics, And Natural Selection.Mavaddat Javid - manuscript
    The eugenics movement was not the anomaly of just one country. In its day, it enamoured industrialized nations throughout the Western world. In the end, the eugenics movement ultimately did not recover from the stigma it sustained as a result of the Second World War. However, with the advancement of genetic engineering and the researches into embryonic stem cells, discussions about eugenics are becoming relevant once more, and it will be the responsibility of the informed (and not (...)
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  26. Stem Cell Lineages: Between Cell and Organism.Melinda Bonnie Fagan - 2017 - Philosophy, Theory, and Practice in Biology 9 (6).
    Ontologies of living things are increasingly grounded on the concepts and practices of current life science. Biological development is a process, undergone by living things, which begins with a single cell and (in an important class of cases) ends with formation of a multicellular organism. The process of development is thus prima facie central for ideas about biological individuality and organismality. However, recent accounts of these concepts do not engage developmental biology. This paper aims to fill the gap, proposing the (...)
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  27. Stem Cell Research and Same Sex Reproduction.Thomas Douglas, Catherine Harding, Hannah Bourne & Julian Savulescu - 2012 - In Muireann Quigley, Sarah Chan & John Harris (eds.), Stem Cells: New Frontiers in Science and Ethics. World Scientific.
    Recent advances in stem cell research suggest that in the future it may be possible to create eggs and sperm from human stem cells through a process that we term in vitro gametogenesis (IVG). IVG would allow treatment of some currently untreatable forms of infertility. It may also allow same-sex couples to have genetically-related children. For example, cells taken from one man could potentially be used to create an egg, which could then be fertilised using naturally (...)
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  28. Stem Cells and the Microenvironment: Reciprocity with Asymmetry in Regenerative Medicine.Militello Guglielmo & Bertolaso Marta - 2022 - Acta Biotheoretica 70 (4):1-27.
    Much of the current research in regenerative medicine concentrates on stem-cell therapy that exploits the regenerative capacities of stem cells when injected into different types of human tissues. Although new therapeutic paths have been opened up by induced pluripotent cells and human mesenchymal cells, the rate of success is still low and mainly due to the difficulties of managing cell proliferation and differentiation, giving rise to non-controlled stem cell differentiation that ultimately leads to cancer. (...)
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  29. Stem Cells Dependently Arising and Empty.Sun Kyeong Yu - 2020 - In Buddhism and Culture (Buddhist magazine in Korea). Seoul, South Korea:
    Stem Cells Dependently Arising and Empty” May 2021, Buddhism and Culture (a Korean-language Buddhist magazine sponsored by the Foundation for the Promotion of Korean Buddhism), Korea.
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  30. Human stem-cell-derived embryo models: When bioethical normativity meets biological ontology.Adrian Villalba - 2024 - Developmental Biology 508.
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  31. Stem cells: biopsy on frozen embryos.Peter Schwartz - 2007 - Hastings Center Report 37 (1):7.
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  32. A Critical Examination of the Question of Personhood in Stem Cell Research.Diana-Abasi Ibanga - 2016 - IOSR Journal of HumanitieS and Social Science 21 (8):6-13.
    Stem cell research programme has been celebrated world over as the most promising medical research in the 21st century. However, the method of stem cell research involves the use and unavoidable destruction of human embryo. As a result of this, many theologians, scholars and analysts have condemned the research programme. Their argument is that the embryo use in stem cell research is human person; hence it is immoral. This paper therefore aims at analyzing and examining the issue (...)
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  33. Ethical issues of using umbilical cord blood stem cell therapy of John Stuart Mill perspective.Pattamawadee Sankheangaew - 2021 - Journal of Philosophy 1.
    This academic paper on Ethical issues of using umbilical cord blood stem cell therapy of John Stuart Mill perspective aim to investigate the new approaches in the treatment of diseases by using umbilical cord blood stem cells. And also to study ethical issues from the use of umbilical cord blood stem cells in the treatment of diseases considered by Mill’s utilitarianism. 21st century, the medical industry was interested in organ transplantation from stem cells (...)
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  34. 'Trust us... we're doctors': Science, media, and ethics in the Hwang stem cell controversy.Robert Sparrow - 2006 - Journal of Communication Research 43 (1):5-24.
    When doubts were first raised about the veracity of the dramatic advances in stem cell research announced by Professor Hwang Woo-Suk, a significant minority response was to question the qualifications of journalists to investigate the matter. In this paper I examine the contemporary relationships between science, scientists, the public, and the media. In the modern context the progress of science often relies on the media to mobilise public support for research and also for the purpose of communication within the (...)
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  35. Good science and good ethics: why we should discourage payment for eggs in stem cell researchonation.Donna Dickenson - 2009 - Nature Reviews Genetics 10 (11):743.
    Payment for eggs used in stem cell research puts women at unacceptable risk and encourages exploitative commodification of the female body. Thanks to the development of induced pluripotent stem cells, however, we no longer face a choice between good science and good ethics.
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  36. Remark on Regenerative Medicine and Potential Utilization of Low-Intensity Laser Photobiomodulation to Activate Human Stem Cells.Victor Christianto, Florentin Smarandache & Robert N. Boyd - 2023 - Bio-Science Research Bulletin 39 (2):52-55.
    Recently, a friend of one of these writers told her story of using one of a healthcare product to activate her stem cells as part of regenerative medicine. Regenerative medicine is a field of medicine that seeks to repair or replace damaged or diseased tissues and organs. This can be done through a variety of methods, including stem cell therapy, tissue engineering, and gene therapy. This is a short review article on this rapid field called regenerative medicine, (...)
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  37. Skepticism About the “Convertibility” of Induced Pluripotent Stem Cells.Thomas V. Cunningham - 2013 - American Journal of Bioethics 13 (1):40-42.
    No abstract available. First paragraph: In this issue’s target article, Stier and Schoene-Siefert purport to ‘depotentialize’ the argument from potentiality based on their claim that any human cell may be “converted” into a morally significant entity, and consequently, the argument from potentiality finally succumbs to a reductio ad absurdum. I aim to convey two reasons for skepticism about the innocuousness of the notion of cell convertibility, and hence, the cogency of their argument.
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  38. Somatic Cell Therapy: A Genetic Rescue for a Tattered Immune System?Bryn Williams-Jones - 2012 - BioéthiqueOnline 1:4.
    The case of Andrew Gobea, the first child to receive experimental gene therapy for SCID, and a reflection on the associated ethical implications of gene therapy research.
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  39. Struggle within: evolution and ecology of somatic cell populations.Bartlomiej Swiatczak - 2021 - Cellular and Molecular Life Sciences 78 (21):6797-6806.
    The extent to which normal (nonmalignant) cells of the body can evolve through mutation and selection during the lifetime of the organism has been a major unresolved issue in evolutionary and developmental studies. On the one hand, stable multicellular individuality seems to depend on genetic homogeneity and suppression of evolutionary conflicts at the cellular level. On the other hand, the example of clonal selection of lymphocytes indicates that certain forms of somatic mutation and selection are concordant with the organism-level (...)
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  40. Embryo loss and double effect.Ezio Di Nucci - 2013 - Journal of Medical Ethics 39 (8):537-540.
    I defend the argument that if embryo loss in stem cell research is morally problematic, then embryo loss in in vivo conception is similarly morally problematic. According to a recent challenge to this argument, we can distinguish between in vivo embryo loss and the in vitro embryo loss of stem cell research by appealing to the doctrine of double effect. I argue that this challenge fails to show that in vivo embryo loss is a mere unintended side effect (...)
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  41. The threatened trade in human ova.Donna Dickenson - 2004 - Nature Reviews Genetics 5 (3):157.
    It is well known that there is a shortage of human ova for in vitro fertilization (IVF) purposes, but little attention has been paid to the way in which the demand for ova in stem-cell technologies is likely to exacerbate that shortfall and create a trade in human eggs. Because the 'Dolly' technology relies on enucleated ova in large quantities, allowing for considerable wastage, there is a serious threat that commercial and research demands for human eggs will grow exponentially (...)
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  42. Respecting Diversity, Respecting Complexity.Judith Andre - 2002 - Law Review of Michigan State University-Detroit College of Law 2002 (4):911-916.
    A discussion of the ethics of stem cell research, and attempts to regulate it.
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  43. Sentimentalism and Metaphysical Beliefs.Noriaki Iwasa - 2010 - Prolegomena 9 (2):271-286.
    This essay first introduces the moral sense theories of Francis Hutcheson, David Hume, and Adam Smith, and clarifies important differences between them. It then examines whether moral judgment based on the moral sense or moral sentiments varies according to one's metaphysical beliefs. For this, the essay mainly applies those theories to such issues as stem cell research, abortion, and active euthanasia. In all three theories, false religious beliefs can distort moral judgment. In Hutcheson's theory, answers to stem cell (...)
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  44. Disappearing women, vanishing ladies and property in embryos.Donna Dickenson - 2017 - International Journal of Law and the Biosciences 4:1-6.
    Guidelines on embryo storage prioritise 'respect for the embryo' above the wishes of the women whose labour and tissue have gone into creating the embryo in the first place, effectively making women and the female body disappear. In this article I draw a parallel between this phenomenon relating to embryo storage and other instances of a similar phenomenon that I have called 'the lady vanishes', particularly in stem cell and 'mitochondrial transfer' research. I suggest that a modified property regime (...)
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  45. Self-empowerment of life through RNA networks, cells and viruses.Villarreal Luis & Witzany Guenther - 2023 - F1000 Research 12 (138).
    Our understanding of the key players in evolution and of the development of all organisms in all domains of life has been aided by current knowledge about RNA stem-loop groups, their proposed interaction motifs in an early RNA world and their regulative roles in all steps and substeps of nearly all cellular processes, such as replication, transcription, translation, repair, immunity and epigenetic marking. Cooperative evolution was enabled by promiscuous interactions between single-stranded regions in the loops of naturally forming (...)-loop structures in RNAs. It was also shown that cooperative RNA stem-loops outcompete selfish ones and provide foundational self-constructive groups (ribosome, editosome, spliceosome, etc.). Self-empowerment from abiotic matter to biological behavior does not just occur at the beginning of biological evolution; it is also essential for all levels of socially interacting RNAs, cells and viruses. (shrink)
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  46.  96
    Re-defining the human embryo: A legal perspective on the creation of embryos in research.Íñigo De Miguel Beriain, Jon Rueda & Adrian Villalba - 2024 - EMBO Reports.
    The notion of the human embryo is not immutable. Various scientific and technological breakthroughs in reproductive biology have compelled us to revisit the definition of the human embryo during the past 2 decades. Somatic cell nuclear transfer, oocyte haploidisation and, more recently, human stem cell-derived embryo models have challenged this scientific term, which has both ethical and legal repercussions. Here, we offer a legal perspective to identify a universally accepted definition of ‘embryo’ which could help to ease and unify (...)
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  47. Bioethics: All That Matters.Donna Dickenson - 2012 - London: Hodder.
    Should we do whatever science lets us do? This short introduction in the 'All That Matters' series shows how developments in biotechnology, such as genetics, stem cell research and artificial reproduction, arouse both our greatest hopes and our greatest fears. Many people invest the new biotechnology with all the aspirations and faith once accorded to religious salvation. But does everyone benefit equally from scientific progress? This book argues that although we've entered new scientific territory, there is no need to (...)
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  48. Self-empowerment of life through RNA networks, cells and viruses. [REVIEW]Witzany Guenther - 2023 - F1000Research 12 (138):1-27.
    Our understanding of the key players in evolution and of the development of all organisms in all domains of life has been aided by current knowledge about RNA stem-loop groups, their proposed interaction motifs in an early RNA world and their regulative roles in all steps and substeps of nearly all cellular processes, such as replication, transcription, translation, repair, immunity and epigenetic marking. Cooperative evolution was enabled by promiscuous interactions between single-stranded regions in the loops of naturally forming (...)-loop structures in RNAs. It was also shown that cooperative RNA stem-loops outcompete selfish ones and provide foundational self-constructive groups (ribosome, editosome, spliceosome, etc.). Self-empowerment from abiotic matter to biological behavior does not just occur at the beginning of biological evolution; it is also essential for all levels of socially interacting RNAs, cells and viruses. (shrink)
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  49.  68
    Artificial Gametes and Human Reproduction in the 21st Century: An Ethical Analysis.A. Villalba - 2024 - Reproductive Sciences.
    Artificial gametes, derived from stem cells, have the potential to enable in vitro fertilization of embryos. Currently, artificial gametes are only being generated in laboratory animals; however, considerable efforts are underway to develop artificial gametes using human cell sources. These artificial gametes are being proposed as a means to address infertility through assisted reproductive technologies. Nonetheless, the availability of artificial gametes obtained from adult organisms can potentially expand the possibilities of reproduction. Various groups, such as same-sex couples, post-menopausal (...)
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  50. The ethics of cellular reprogramming.Anna Smajdor & Adrian Villalba - forthcoming - Cellular Reprogramming 25.
    Louise Brown's birth in 1978 heralded a new era not just in reproductive technology, but in the relationship between science, cells, and society. For the first time, human embryos could be created, selected, studied, manipulated, frozen, altered, or destroyed, outside the human body. But with this possibility came a plethora of ethical questions. Is it acceptable to destroy a human embryo for the purpose of research? Or to create an embryo with the specific purpose of destroying it for research? (...)
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