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  1. Aristotle on Epigenesis.Devin Henry - 2018
    It has become somewhat of a platitude to call Aristotle the first epigenesist insofar as he thought form and structure emerged gradually from an unorganized, amorphous embryo. But modern biology now recognizes two senses of “epigenesis”. The first is this more familiar idea about the gradual emergence of form and structure, which is traditionally opposed to the idea of preformationism. But modern biologists also use “epigenesis” to emphasize the context-dependency of the process itself. Used in this sense development is not (...)
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  2. Self-empowerment of life through RNA networks, cells and viruses. [REVIEW]Witzany Guenther - 2023 - F1000Research 12 (138):1-27.
    Our understanding of the key players in evolution and of the development of all organisms in all domains of life has been aided by current knowledge about RNA stem-loop groups, their proposed interaction motifs in an early RNA world and their regulative roles in all steps and substeps of nearly all cellular processes, such as replication, transcription, translation, repair, immunity and epigenetic marking. Cooperative evolution was enabled by promiscuous interactions between single-stranded regions in the loops of naturally forming stem-loop structures (...)
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  3. Many Paths to Anticipatory Behavior: Anticipatory Model Acquisition Across Phylogenetic and Ontogenetic Timescales.Matthew Sims - 2023 - Biological Theory 1 (2):114-133.
    Under the assumption that anticipatory models are required for anticipatory behavior, an important question arises about the different manners in which organisms acquire anticipatory models. This article aims to articulate four different non-exhaustive ways that anticipatory models might possibly be acquired over both phylogenetic and ontogenetic timescales and explore the relationships among them. To articulate these different model-acquisition mechanisms, four schematics will be introduced, each of which represents a particular acquisition structure that can be used for the purposes of comparison, (...)
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  4. Rethinking hereditary relations: the reconstitutor as the evolutionary unit of heredity.Sophie J. Veigl, Javier Suárez & Adrian Stencel - 2022 - Synthese 200 (5):1-42.
    This paper introduces the reconstitutor as a comprehensive unit of heredity within the context of evolutionary research. A reconstitutor is the structure resulting from a set of relationships between different elements or processes that are actively involved in the recreation of a specific phenotypic variant in each generation regardless of the biomolecular basis of the elements or whether they stand in a continuous line of ancestry. Firstly, we justify the necessity of introducing the reconstitutor by showing the limitations of other (...)
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  5. Thinking embodiment with genetics: epigenetics and postgenomic biology in embodied cognition and enactivism.Maurizio Meloni & Jack Reynolds - 2020 - Synthese 198 (11):10685-10708.
    The role of the body in cognition is acknowledged across a variety of disciplines, even if the precise nature and scope of that contribution remain contentious. As a result, most philosophers working on embodiment—e.g. those in embodied cognition, enactivism, and ‘4e’ cognition—interact with the life sciences as part of their interdisciplinary agenda. Despite this, a detailed engagement with emerging findings in epigenetics and post-genomic biology has been missing from proponents of this embodied turn. Surveying this research provides an opportunity to (...)
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  6. Anthropocene: The philosophy of Biotechnology.Valentin Cheshko, Glazko Valery & Ivanitskaya Lida - 2018 - Moscow, Russia: Kurs INFRA-M.
    The theory of evolution of complex, including the humans system and algorithm for its constructing are a synthesis of evolutionary epistemology, philosophical anthropology and concrete scientific empirical basis in modern science,. In other words, natural philosophy is regaining the status bar element theoretical science in the era of technology-driven evolution. The co-evolutionary concept of 3-modal stable evolutionary strategy of Homo sapiens is developed. The concept based on the principle of evolutionary complementarity of anthropogenesis: value of evolutionary risk and evolutionary path (...)
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  7. Hierarchy Theory of Evolution and the Extended Evolutionary Synthesis: Some Epistemic Bridges, Some Conceptual Rifts.Alejandro Fábregas-Tejeda & Francisco Vergara-Silva - 2018 - Evolutionary Biology 45 (2):127-139.
    Contemporary evolutionary biology comprises a plural landscape of multiple co-existent conceptual frameworks and strenuous voices that disagree on the nature and scope of evolutionary theory. Since the mid-eighties, some of these conceptual frameworks have denounced the ontologies of the Modern Synthesis and of the updated Standard Theory of Evolution as unfinished or even flawed. In this paper, we analyze and compare two of those conceptual frameworks, namely Niles Eldredge’s Hierarchy Theory of Evolution (with its extended ontology of evolutionary entities) and (...)
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  8. Biopolitical Barriers to a Potterian Bioethics: The (Potentially) Missed Opportunity of Epigenetics.Charles Dupras, Bryn Williams-Jones & Vardit Ravitsky - 2017 - American Journal of Bioethics 17 (9):15-17.
    Lee (2017) calls for greater attention to the shared epistemological and normative grounds of both public health ethics and environmental ethics, and to Potter’s original conception of bioethics, which, as she rightly observes, has been largely disregarded in contemporary North American bioethics scholarship and practice. In a previous publication we also argued in favor of reviving the Potterian approach to bioethics; we built a case grounded in “the relatively new field of molecular epigenetics [that] provides novel information that should serve (...)
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  9. Genetic, epigenetic and exogenetic information in development and evolution.Paul Edmund Griffiths - 2017 - Interface Focus 7 (5).
    The idea that development is the expression of information accumulated during evolution and that heredity is the transmission of this information is surprisingly hard to cash out in strict, scientific terms. This paper seeks to do so using the sense of information introduced by Francis Crick in his sequence hypothesis and central dogma of molecular biology. It focuses on Crick's idea of precise determination. This is analysed using an information-theoretic measure of causal specificity. This allows us to reconstruct some of (...)
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  10. Review of Are We Hardwired by Clark and Grunstein (2000).Michael Starks - 2017 - Philosophy, Human Nature and the Collapse of Civilization Michael Starks 3rd Ed. (2017).
    This is an excellent review of gene/environment interactions on behavior and, in spite of being a bit dated, is an easy and worthwhile read. They start with twin studies which show the overwhelming impact of genetics on behavior. They note the increasingly well known studies of Judith Harris which extend and summarize the facts that shared home environment has almost no effect on behavior and that adopted children grow up to be as different from their stepbrothers and sisters as people (...)
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  11. Eine neue Sicht der Evolution: Ist es nur der Zufall, der sie leitet?Paul Gottlob Layer - 2016 - BRIEFE Zur Orientierung Im Konflikt Mensch - Erde, Evangelische Akademie Sachsen-Anhalt E.V 121 (4):16-24.
    Nach neodarwinistischem Verständnis der Evolution entstehen neue Organismen letztlich durch rein zufällige Mutationsprozesse auf genetischer Ebene. Ihre Überlebenschancen werden dann durch die jeweilig herrschende Umwelt begünstigt oder unterdrückt. Die Evolution ist demnach nur vom reinen Zufall geleitet. Neuere Einsichten aus Entwicklungsbiologie (EvoDevo) und Epigenetik haben unsere Sicht der Evolutionsabläufe jedoch deutlich erweitert. Dabei kommt der Umwelt eine lenkende Rolle zu, der reine Zufall verliert an Bedeutung. Damit lässt sich naturwissenschaftliches Verständnis wieder besser mit herkömmlichen Schöpfungsbildern versöhnen.
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  12. Wie Epigenetik unser Weltbild ins Lot bringen kann.Paul Gottlob Layer - 2016 - BRIEFE Zur Orientierung Im Konflikt Mensch - Erde, Evangelische Akademie Sachsen-Anhalt E.V 121 (4):25-33.
    Seit der Aufklärung versucht der Mensch, Gott abzuschaffen. Dabei fällt der Zufälligkeit, und damit auch der Ziellosigkeit in der darwinistischen Sicht der Evolution besonderes Gewicht zu. Diese weithin akzeptierten Dogmen stehen diametral gegen jahrtausendealte Vorstellungen, die letztlich in allen Kulturen und Religionen hervorgebracht wurden, daß die Natur eine Schöpfung Gottes sei, in der der Mensch das höchste, Gott-ebenbildliche Wesen sei. Nach Erkenntnissen der klassischen Genetik schienen Gene an die Stelle von Gott getreten zu sein: sie haben absolute Gewalt und beherrschen (...)
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  13. Metaanalysis of psychoanalysis.Andrej Poleev - 2016 - Enzymes.
    The perspective revolution of Sigmund Freud: An update.
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  14. Developmental Systems Theory.Paul Griffiths & Adam Hochman - 2015 - eLS:1-7.
    Developmental systems theory (DST) is a wholeheartedly epigenetic approach to development, inheritance and evolution. The developmental system of an organism is the entire matrix of resources that are needed to reproduce the life cycle. The range of developmental resources that are properly described as being inherited, and which are subject to natural selection, is far wider than has traditionally been allowed. Evolution acts on this extended set of developmental resources. From a developmental systems perspective, development does not proceed according to (...)
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  15. Development of Cultural Consciousness: From the Perspective of a Social Constructivist.Gregory M. Nixon - 2015 - International Journal of Education and Social Science 2 (10):119-136.
    In this condensed survey, I look to recent perspectives on evolution suggesting that cultural change likely alters the genome. Since theories of development are nested within assumptions about evolution (evo-devo), I next review some oft-cited developmental theories and other psychological theories of the 20th century to see if any match the emerging perspectives in evolutionary theory. I seek theories based neither in nature (genetics) nor nurture (the environment) but in the creative play of human communication responding to necessity. This survey (...)
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  16. Les nouvelles biotechnologies en questions. Préface de Jean Audouze. Paris, Éditions Salvator , 2013, 127 p. [REVIEW]Philippe Gagnon - 2014 - Laval Théologique et Philosophique 70 (1):205-208.
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  17. Social Epigenetics and Equality of Opportunity.Michele Loi, Lorenzo Del Savio & Elia Stupka - 2013 - Public Health Ethics 6 (2):142-153.
    Recent epidemiological reports of associations between socioeconomic status and epigenetic markers that predict vulnerability to diseases are bringing to light substantial biological effects of social inequalities. Here, we start the discussion of the moral consequences of these findings. We firstly highlight their explanatory importance in the context of the research program on the Developmental Origins of Health and Disease (DOHaD) and the social determinants of health. In the second section, we review some theories of the moral status of health inequalities. (...)
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  18. The Species Problem: A Philosophical Analysis. By Richard A. Richards. (Cambridge UP, 2010. Pp. x + 236. Price £50.00.).Catherine Kendig - 2012 - Philosophical Quarterly 62 (247):405-408.
    Book review of Richard A. Richards' The Species Problem: A Philosophical Analysis.
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  19. EvoDevo: die molekulare Entwicklungsbiologie als Schlüssel zum Verständnis der Evolutionstheorie.Paul Gottlob Layer - 2009 - Zeitschrift Für Pädagogik Und Theologie 61 (4):322-333.
    Darwin´s Erkenntnis über die Abstammung der Arten durch Mutation und Selektion sind in aller Munde, dass aber darüber im Detail noch viel Unklarheit herrscht, ist weniger bekannt. Es sind Fortschritte der Entwicklungsbiologie, die erst seit wenigen Jahren uns molekulare Erklärungsmuster an die Hand geben, mit denen die Entstehung neuer Arten besser verständlich wird. Es handelt sich um die Aufklärung der Wirkungsweise von Genen und ihren molekularen Produkten, die während der embryonalen Entwicklung von Tier und Mensch dafür sorgen, daß der Organismus (...)
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  20. Epigenetics, Evolution, and Us.W. Malcolm Byrnes - 2003 - The National Catholic Bioethics Quarterly 3 (3):489-500.
    This essay moves along broad lines from molecular biology to evolutionary biology and ecology to theology. Its objectives are to: 1) present some recent scientific findings in the emerging field of epigenetics that indicate that it is “the genome in context,” not genes per se, that are important in biological development and evolution; 2) show that this weakens the gene-centric neo-Darwinist explanation of evolution which, in fact, shares a certain preformationist orientation with intelligent design theory; 3) argue that the evidence (...)
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  21. Epigenetic is back!Massimo Pigliucci - 2003 - Cell Cycle 2 (1):34-35.
    Back in 1942, C.H. Waddington proposed a new mechanism of evolutionary change, which he termed “genetic assimilation”.1,2 The idea was that certain environmental or genetic factors can disrupt the normally canalized (i.e., stable) course of development of living organisms. This disruption may then generate phenotypic variation that could allow a population to persist in a novel or stressful environment until new mutations would eventually let natural selection fix (“assimilate”) the advantageous phenotypic variants.
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  22. Buffer zone.Massimo Pigliucci - 2002 - Nature 417 (598):599.
    Living organisms are caught between a hammer and an anvil, evolutionarily speaking. On the one hand, they need to buffer the influences of genetic mutations and environmental stresses if they are to develop normally and maintain a coherent and functional form. On the other, stabiliz- ing one’s development too much may mean not being able to respond at all to changes in the environment and starting down the primrose path to extinction. On page 618 of this issue, Queitsch et al.1 (...)
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  23. August Weismann on Germ-Plasm Variation.Rasmus Grønfeldt Winther - 2001 - Journal of the History of Biology 34 (3):517-555.
    August Weismann is famous for having argued against the inheritance of acquired characters. However, an analysis of his work indicates that Weismann always held that changes in external conditions, acting during development, were the necessary causes of variation in the hereditary material. For much of his career he held that acquired germ-plasm variation was inherited. An irony, which is in tension with much of the standard twentieth-century history of biology, thus exists – Weismann was not a Weismannian. I distinguish three (...)
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  24. Darwin on Variation and Heredity.Rasmus Grønfeldt Winther - 2000 - Journal of the History of Biology 33 (3):425-455.
    Darwin's ideas on variation, heredity, and development differ significantly from twentieth-century views. First, Darwin held that environmental changes, acting either on the reproductive organs or the body, were necessary to generate variation. Second, heredity was a developmental, not a transmissional, process; variation was a change in the developmental process of change. An analysis of Darwin's elaboration and modification of these two positions from his early notebooks (1836-1844) to the last edition of the /Variation of Animals and Plants Under Domestication/ (1875) (...)
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  25. Herbert Spencer's Epigenetic Epistemology.C. U. M. Smith - 1983 - Studies in History and Philosophy of Science Part A 14 (1):1.
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  26. An evolutionary metaphysics of human enhancement technologies.Valentin Cheshko - manuscript
    The monograph is an English, expanded and revised version of the book Cheshko, V. T., Ivanitskaya, L.V., & Glazko, V.I. (2018). Anthropocene. Philosophy of Biotechnology. Moscow, Course. The manuscript was completed by me on November 15, 2019. It is a study devoted to the development of the concept of a stable evolutionary human strategy as a unique phenomenon of global evolution. The name “An Evolutionary Metaphysics (Cheshko, 2012; Glazko et al., 2016). With equal rights, this study could be entitled “Biotechnology (...)
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